Sort by
Items per page

Send to

Choose Destination

Search results

Items: 21


Translating Systems Medicine Into Clinical Practice: Examples From Pulmonary Medicine With Genetic Disorders, Infections, Inflammations, Cancer Genesis, and Treatment Implication of Molecular Alterations in Non-small-cell Lung Cancers and Personalized Medicine.

Pinsolle J, McLeer-Florin A, Giaj Levra M, de Fraipont F, Emprou C, Gobbini E, Toffart AC.

Front Med (Lausanne). 2019 Oct 29;6:233. doi: 10.3389/fmed.2019.00233. eCollection 2019. Review.


Current opinions in immune checkpoint inhibitors rechallenge in solid cancers.

Gobbini E, Charles J, Toffart AC, Leccia MT, Moro-Sibilot D, Giaj Levra M.

Crit Rev Oncol Hematol. 2019 Dec;144:102816. doi: 10.1016/j.critrevonc.2019.102816. Epub 2019 Oct 5. Review.


Real-world outcomes according to treatment strategies in ALK-rearranged non-small-cell lung cancer (NSCLC) patients: an Italian retrospective study.

Gobbini E, Chiari R, Pizzutillo P, Bordi P, Ghilardi L, Pilotto S, Osman G, Cappuzzo F, Cecere F, Riccardi F, Scotti V, Martelli O, Borra G, Maiello E, Rossi A, Graziano P, Gregorc V, Casartelli C, Sergi C, Del Conte A, Delmonte A, Bareggi C, Cortinovis D, Rizzo P, Tabbò F, Rossi G, Bria E, Galetta D, Tiseo M, Di Maio M, Novello S.

Clin Transl Oncol. 2019 Oct 19. doi: 10.1007/s12094-019-02222-8. [Epub ahead of print]


Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization to High-Dimensional Analyses.

Hubert M, Gobbini E, Bendriss-Vermare N, Caux C, Valladeau-Guilemond J.

Cancers (Basel). 2019 Jul 30;11(8). pii: E1082. doi: 10.3390/cancers11081082. Review.


Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity.

Gobbini E, Vertemara J, Longhese MP.

Mol Cell Oncol. 2018 Aug 24;5(5):e1511208. doi: 10.1080/23723556.2018.1511208. eCollection 2018.


Is there a room for immune checkpoint inhibitors in early stage non-small cell lung cancer?

Gobbini E, Giaj Levra M.

J Thorac Dis. 2018 May;10(Suppl 13):S1427-S1437. doi: 10.21037/jtd.2018.01.81. Review.


The MRX complex regulates Exo1 resection activity by altering DNA end structure.

Gobbini E, Cassani C, Vertemara J, Wang W, Mambretti F, Casari E, Sung P, Tisi R, Zampella G, Longhese MP.

EMBO J. 2018 Aug 15;37(16). pii: e98588. doi: 10.15252/embj.201798588. Epub 2018 Jun 19.


Time trends of overall survival among metastatic breast cancer patients in the real-life ESME cohort.

Gobbini E, Ezzalfani M, Dieras V, Bachelot T, Brain E, Debled M, Jacot W, Mouret-Reynier MA, Goncalves A, Dalenc F, Patsouris A, Ferrero JM, Levy C, Lorgis V, Vanlemmens L, Lefeuvre-Plesse C, Mathoulin-Pelissier S, Petit T, Uwer L, Jouannaud C, Leheurteur M, Lacroix-Triki M, Cleaud AL, Robain M, Courtinard C, Cailliot C, Perol D, Delaloge S.

Eur J Cancer. 2018 Jun;96:17-24. doi: 10.1016/j.ejca.2018.03.015. Epub 2018 Apr 13.


Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance.

Cassani C, Gobbini E, Vertemara J, Wang W, Marsella A, Sung P, Tisi R, Zampella G, Longhese MP.

Nucleic Acids Res. 2018 Apr 6;46(6):2990-3008. doi: 10.1093/nar/gky086.


Effect of Contract Research Organization Bureaucracy in Clinical Trial Management: A Model From Lung Cancer.

Gobbini E, Pilotto S, Pasello G, Polo V, Di Maio M, Arizio F, Galetta D, Petrillo P, Chiari R, Matocci R, Di Costanzo A, Di Stefano TS, Aglietta M, Cagnazzo C, Sperduti I, Bria E, Novello S.

Clin Lung Cancer. 2018 Mar;19(2):191-198. doi: 10.1016/j.cllc.2017.10.012. Epub 2017 Oct 28.


Molecular profiling in Italian patients with advanced non-small-cell lung cancer: An observational prospective study.

Gobbini E, Galetta D, Tiseo M, Graziano P, Rossi A, Bria E, Di Maio M, Rossi G, Gregorc V, Riccardi F, Scotti V, Ceribelli A, Buffoni L, Delmonte A, Franchina T, Migliorino MR, Cortinovis D, Pisconti S, Bordi P, Catino A, Maiello E, Arizio F, Novello S; other Co-Authors.

Lung Cancer. 2017 Sep;111:30-37. doi: 10.1016/j.lungcan.2017.06.009. Epub 2017 Jun 16.


Functions and regulation of the MRX complex at DNA double-strand breaks.

Gobbini E, Cassani C, Villa M, Bonetti D, Longhese MP.

Microb Cell. 2016 Jul 27;3(8):329-337. doi: 10.15698/mic2016.08.517. Review.


Intercalated Chemotherapy and Epidermal Growth Factor Receptor Inhibitors for Patients With Advanced Non-Small-cell Lung Cancer: A Systematic Review and Meta-analysis.

La Salvia A, Rossi A, Galetta D, Gobbini E, De Luca E, Novello S, Di Maio M.

Clin Lung Cancer. 2017 Jan;18(1):23-33.e1. doi: 10.1016/j.cllc.2016.08.006. Epub 2016 Oct 28. Review.


Coupling end resection with the checkpoint response at DNA double-strand breaks.

Villa M, Cassani C, Gobbini E, Bonetti D, Longhese MP.

Cell Mol Life Sci. 2016 Oct;73(19):3655-63. doi: 10.1007/s00018-016-2262-6. Epub 2016 May 3. Review.


Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks.

Cassani C, Gobbini E, Wang W, Niu H, Clerici M, Sung P, Longhese MP.

PLoS Biol. 2016 Feb 22;14(2):e1002387. doi: 10.1371/journal.pbio.1002387. eCollection 2016 Feb.


Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity.

Gobbini E, Villa M, Gnugnoli M, Menin L, Clerici M, Longhese MP.

PLoS Genet. 2015 Nov 19;11(11):e1005685. doi: 10.1371/journal.pgen.1005685. eCollection 2015 Nov.


EGFR mutant allelic-specific imbalance assessment in routine samples of non-small cell lung cancer.

Malapelle U, Vatrano S, Russo S, Bellevicine C, de Luca C, Sgariglia R, Rocco D, de Pietro L, Riccardi F, Gobbini E, Righi L, Troncone G.

J Clin Pathol. 2015 Sep;68(9):739-41. doi: 10.1136/jclinpath-2015-203101. Epub 2015 Jun 5.


Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection.

Bonetti D, Villa M, Gobbini E, Cassani C, Tedeschi G, Longhese MP.

EMBO Rep. 2015 Mar;16(3):351-61. doi: 10.15252/embr.201439764. Epub 2015 Jan 30.


Telomere uncapping at the crossroad between cell cycle arrest and carcinogenesis.

Gobbini E, Trovesi C, Cassani C, Longhese MP.

Mol Cell Oncol. 2014 Jul 28;1(1):e29901. doi: 10.4161/mco.29901. eCollection 2014. Review.


Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks.

Gobbini E, Cesena D, Galbiati A, Lockhart A, Longhese MP.

DNA Repair (Amst). 2013 Oct;12(10):791-9. doi: 10.1016/j.dnarep.2013.07.009. Epub 2013 Aug 13. Review.


G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint.

Manfrini N, Gobbini E, Baldo V, Trovesi C, Lucchini G, Longhese MP.

Mol Cell Biol. 2012 Dec;32(24):4971-85. doi: 10.1128/MCB.00956-12. Epub 2012 Oct 8.

Supplemental Content

Loading ...
Support Center