Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35


Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections.

Beneke T, Demay F, Hookway E, Ashman N, Jeffery H, Smith J, Valli J, Becvar T, Myskova J, Lestinova T, Shafiq S, Sadlova J, Volf P, Wheeler RJ, Gluenz E.

PLoS Pathog. 2019 Jun 26;15(6):e1007828. doi: 10.1371/journal.ppat.1007828. eCollection 2019 Jun.


LeishGEdit: A Method for Rapid Gene Knockout and Tagging Using CRISPR-Cas9.

Beneke T, Gluenz E.

Methods Mol Biol. 2019;1971:189-210. doi: 10.1007/978-1-4939-9210-2_9.


Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping.

Costa FC, Francisco AF, Jayawardhana S, Calderano SG, Lewis MD, Olmo F, Beneke T, Gluenz E, Sunter J, Dean S, Kelly JM, Taylor MC.

PLoS Negl Trop Dis. 2018 Apr 2;12(4):e0006388. doi: 10.1371/journal.pntd.0006388. eCollection 2018 Apr.


Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei.

Ooi CP, Smith TK, Gluenz E, Wand NV, Vaughan S, Rudenko G.

Traffic. 2018 Jun;19(6):391-405. doi: 10.1111/tra.12561. Epub 2018 Apr 6.


Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit.

Martel D, Beneke T, Gluenz E, Späth GF, Rachidi N.

Biomed Res Int. 2017;2017:4635605. doi: 10.1155/2017/4635605. Epub 2017 Nov 29.


A CRISPR Cas9 high-throughput genome editing toolkit for kinetoplastids.

Beneke T, Madden R, Makin L, Valli J, Sunter J, Gluenz E.

R Soc Open Sci. 2017 May 3;4(5):170095. doi: 10.1098/rsos.170095. eCollection 2017 May.


KHARON Is an Essential Cytoskeletal Protein Involved in the Trafficking of Flagellar Membrane Proteins and Cell Division in African Trypanosomes.

Sanchez MA, Tran KD, Valli J, Hobbs S, Johnson E, Gluenz E, Landfear SM.

J Biol Chem. 2016 Sep 16;291(38):19760-73. doi: 10.1074/jbc.M116.739235. Epub 2016 Aug 3.


Basal body multipotency and axonemal remodelling are two pathways to a 9+0 flagellum.

Wheeler RJ, Gluenz E, Gull K.

Nat Commun. 2015 Dec 15;6:8964. doi: 10.1038/ncomms9964.


Comparative Life Cycle Transcriptomics Revises Leishmania mexicana Genome Annotation and Links a Chromosome Duplication with Parasitism of Vertebrates.

Fiebig M, Kelly S, Gluenz E.

PLoS Pathog. 2015 Oct 9;11(10):e1005186. doi: 10.1371/journal.ppat.1005186. eCollection 2015 Oct.


Kharon1 null mutants of Leishmania mexicana are avirulent in mice and exhibit a cytokinesis defect within macrophages.

Tran KD, Vieira DP, Sanchez MA, Valli J, Gluenz E, Landfear SM.

PLoS One. 2015 Aug 12;10(8):e0134432. doi: 10.1371/journal.pone.0134432. eCollection 2015.


cAMP signalling in trypanosomatids: role in pathogenesis and as a drug target.

Makin L, Gluenz E.

Trends Parasitol. 2015 Aug;31(8):373-9. doi: 10.1016/ Epub 2015 May 21. Review.


Scanning and three-dimensional electron microscopy methods for the study of Trypanosoma brucei and Leishmania mexicana flagella.

Gluenz E, Wheeler RJ, Hughes L, Vaughan S.

Methods Cell Biol. 2015;127:509-42. doi: 10.1016/bs.mcb.2014.12.011. Epub 2015 Mar 7.


A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids.

Dean S, Sunter J, Wheeler RJ, Hodkinson I, Gluenz E, Gull K.

Open Biol. 2015 Jan;5(1):140197. doi: 10.1098/rsob.140197.


SLaP mapper: a webserver for identifying and quantifying spliced-leader addition and polyadenylation site usage in kinetoplastid genomes.

Fiebig M, Gluenz E, Carrington M, Kelly S.

Mol Biochem Parasitol. 2014 Sep;196(2):71-4. doi: 10.1016/j.molbiopara.2014.07.012. Epub 2014 Aug 8.


The limits on trypanosomatid morphological diversity.

Wheeler RJ, Gluenz E, Gull K.

PLoS One. 2013 Nov 19;8(11):e79581. doi: 10.1371/journal.pone.0079581. eCollection 2013.


Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1.

Povelones ML, Tiengwe C, Gluenz E, Gull K, Englund PT, Jensen RE.

Mol Microbiol. 2013 Feb;87(4):713-29. doi: 10.1111/mmi.12089. Epub 2013 Jan 21.


Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei.

Povelones ML, Gluenz E, Dembek M, Gull K, Rudenko G.

PLoS Pathog. 2012;8(11):e1003010. doi: 10.1371/journal.ppat.1003010. Epub 2012 Nov 1.


Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis.

Wheeler RJ, Gull K, Gluenz E.

BMC Biol. 2012 Jan 3;10:1. doi: 10.1186/1741-7007-10-1.


An expanded family of proteins with BPI/LBP/PLUNC-like domains in trypanosome parasites: an association with pathogenicity?

Gluenz E, Barker AR, Gull K.

Biochem Soc Trans. 2011 Aug;39(4):966-70. doi: 10.1042/BST0390966. Review.


The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology.

Wheeler RJ, Gluenz E, Gull K.

Mol Microbiol. 2011 Feb;79(3):647-62. doi: 10.1111/j.1365-2958.2010.07479.x. Epub 2010 Dec 13.


Depletion of mitochondrial acyl carrier protein in bloodstream-form Trypanosoma brucei causes a kinetoplast segregation defect.

Clayton AM, Guler JL, Povelones ML, Gluenz E, Gull K, Smith TK, Jensen RE, Englund PT.

Eukaryot Cell. 2011 Mar;10(3):286-92. doi: 10.1128/EC.00290-10. Epub 2011 Jan 14.


The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis.

Gluenz E, Povelones ML, Englund PT, Gull K.

Mol Cell Biol. 2011 Mar;31(5):1012-21. doi: 10.1128/MCB.01176-10. Epub 2010 Dec 20.


The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear roles.

Wickstead B, Carrington JT, Gluenz E, Gull K.

PLoS One. 2010 Nov 23;5(11):e15020. doi: 10.1371/journal.pone.0015020.


Ultrastructural investigation methods for Trypanosoma brucei.

Höög JL, Gluenz E, Vaughan S, Gull K.

Methods Cell Biol. 2010;96:175-96. doi: 10.1016/S0091-679X(10)96008-1.


Flagellum assembly and function during the Leishmania life cycle.

Gluenz E, Ginger ML, McKean PG.

Curr Opin Microbiol. 2010 Aug;13(4):473-9. doi: 10.1016/j.mib.2010.05.008. Epub 2010 Jun 11. Review.


Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans.

Gluenz E, Höög JL, Smith AE, Dawe HR, Shaw MK, Gull K.

FASEB J. 2010 Sep;24(9):3117-21. doi: 10.1096/fj.09-151381. Epub 2010 Apr 6.


Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation.

Smith TK, Vasileva N, Gluenz E, Terry S, Portman N, Kramer S, Carrington M, Michaeli S, Gull K, Rudenko G.

PLoS One. 2009 Oct 26;4(10):e7532. doi: 10.1371/journal.pone.0007532.


The heart of darkness: growth and form of Trypanosoma brucei in the tsetse fly.

Sharma R, Gluenz E, Peacock L, Gibson W, Gull K, Carrington M.

Trends Parasitol. 2009 Nov;25(11):517-24. doi: 10.1016/ Epub 2009 Sep 9. Review.


Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei.

Signorell A, Gluenz E, Rettig J, Schneider A, Shaw MK, Gull K, Bütikofer P.

Mol Microbiol. 2009 May;72(4):1068-79. doi: 10.1111/j.1365-2958.2009.06713.x. Epub 2009 Apr 28.


A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology.

Lindsay ME, Gluenz E, Gull K, Englund PT.

Mol Microbiol. 2008 Dec;70(6):1465-76. doi: 10.1111/j.1365-2958.2008.06493.x. Epub 2008 Oct 22.


Bioinformatic insights to the ESAG5 and GRESAG5 gene families in kinetoplastid parasites.

Barker AR, Wickstead B, Gluenz E, Gull K.

Mol Biochem Parasitol. 2008 Dec;162(2):112-22. doi: 10.1016/j.molbiopara.2008.08.003. Epub 2008 Aug 19.


Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages.

Gluenz E, Sharma R, Carrington M, Gull K.

Mol Microbiol. 2008 Aug;69(3):666-80. doi: 10.1111/j.1365-2958.2008.06320.x. Epub 2008 Jun 28.


Asymmetric cell division as a route to reduction in cell length and change in cell morphology in trypanosomes.

Sharma R, Peacock L, Gluenz E, Gull K, Gibson W, Carrington M.

Protist. 2008 Jan;159(1):137-51. Epub 2007 Oct 10.


Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast.

Gluenz E, Shaw MK, Gull K.

Mol Microbiol. 2007 Jun;64(6):1529-39. Epub 2007 May 18.

Supplemental Content

Loading ...
Support Center