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Constraints to counting bioluminescence producing cells by a commonly used transgene promoter and its implications for experimental design.

Mosaad EO, Futrega K, Seim I, Gloss B, Chambers KF, Clements JA, Doran MR.

Sci Rep. 2019 Aug 5;9(1):11334. doi: 10.1038/s41598-019-46916-z.


Mouse Model of Mutated in Colorectal Cancer Gene Deletion Reveals Novel Pathways in Inflammation and Cancer.

Currey N, Jahan Z, Caldon CE, Tran PN, Benthani F, De Lacavalerie P, Roden DL, Gloss BS, Campos C, Bean EG, Bullman A, Reibe-Pal S, Dinger ME, Febbraio MA, Clarke SJ, Dahlstrom JE, Kohonen-Corish MRJ.

Cell Mol Gastroenterol Hepatol. 2019;7(4):819-839. doi: 10.1016/j.jcmgh.2019.01.009. Epub 2019 Mar 2.


CA2 neuronal activity controls hippocampal low gamma and ripple oscillations.

Alexander GM, Brown LY, Farris S, Lustberg D, Pantazis C, Gloss B, Plummer NW, Jensen P, Dudek SM.

Elife. 2018 Nov 2;7. pii: e38052. doi: 10.7554/eLife.38052.


Realizing the significance of noncoding functionality in clinical genomics.

Gloss BS, Dinger ME.

Exp Mol Med. 2018 Aug 7;50(8):97. doi: 10.1038/s12276-018-0087-0. Review.


Identification of OAF and PVRL1 as candidate genes for an ocular anomaly characterized by Peters anomaly type 2 and ectopia lentis.

David D, Anand D, Araújo C, Gloss B, Fino J, Dinger M, Lindahl P, Pöyhönen M, Hannele L, Lavinha J.

Exp Eye Res. 2018 Mar;168:161-170. doi: 10.1016/j.exer.2017.12.012. Epub 2018 Jan 2.


Intergenic disease-associated regions are abundant in novel transcripts.

Bartonicek N, Clark MB, Quek XC, Torpy JR, Pritchard AL, Maag JLV, Gloss BS, Crawford J, Taft RJ, Hayward NK, Montgomery GW, Mattick JS, Mercer TR, Dinger ME.

Genome Biol. 2017 Dec 28;18(1):241. doi: 10.1186/s13059-017-1363-3.


Machine learning annotation of human branchpoints.

Signal B, Gloss BS, Dinger ME, Mercer TR.

Bioinformatics. 2018 Mar 15;34(6):920-927. doi: 10.1093/bioinformatics/btx688.


Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage.

Betts JA, Moradi Marjaneh M, Al-Ejeh F, Lim YC, Shi W, Sivakumaran H, Tropée R, Patch AM, Clark MB, Bartonicek N, Wiegmans AP, Hillman KM, Kaufmann S, Bain AL, Gloss BS, Crawford J, Kazakoff S, Wani S, Wen SW, Day B, Möller A, Cloonan N, Pearson J, Brown MA, Mercer TR, Waddell N, Khanna KK, Dray E, Dinger ME, Edwards SL, French JD.

Am J Hum Genet. 2017 Aug 3;101(2):255-266. doi: 10.1016/j.ajhg.2017.07.007.


High resolution temporal transcriptomics of mouse embryoid body development reveals complex expression dynamics of coding and noncoding loci.

Gloss BS, Signal B, Cheetham SW, Gruhl F, Kaczorowski DC, Perkins AC, Dinger ME.

Sci Rep. 2017 Jul 27;7(1):6731. doi: 10.1038/s41598-017-06110-5.


Computational Approaches for Functional Prediction and Characterisation of Long Noncoding RNAs.

Signal B, Gloss BS, Dinger ME.

Trends Genet. 2016 Oct;32(10):620-637. doi: 10.1016/j.tig.2016.08.004. Epub 2016 Sep 1. Review.


Unexpected features of the dark proteome.

Perdigão N, Heinrich J, Stolte C, Sabir KS, Buckley MJ, Tabor B, Signal B, Gloss BS, Hammang CJ, Rost B, Schafferhans A, O'Donoghue SI.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15898-903. doi: 10.1073/pnas.1508380112. Epub 2015 Nov 17.


Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer.

Moran-Jones K, Gloss BS, Murali R, Chang DK, Colvin EK, Jones MD, Yuen S, Howell VM, Brown LM, Wong CW, Spong SM, Scarlett CJ, Hacker NF, Ghosh S, Mok SC, Birrer MJ, Samimi G.

Oncotarget. 2015 Dec 29;6(42):44551-62. doi: 10.18632/oncotarget.6082.


The specificity of long noncoding RNA expression.

Gloss BS, Dinger ME.

Biochim Biophys Acta. 2016 Jan;1859(1):16-22. doi: 10.1016/j.bbagrm.2015.08.005. Epub 2015 Aug 19. Review.


Beyond Gene Inactivation: Evolution of Tools for Analysis of Serotonergic Circuitry.

Hainer C, Mosienko V, Koutsikou S, Crook JJ, Gloss B, Kasparov S, Lumb BM, Alenina N.

ACS Chem Neurosci. 2015 Jul 15;6(7):1116-29. doi: 10.1021/acschemneuro.5b00045. Epub 2015 Jul 6. Review.


Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells.

Rogers S, Gloss BS, Lee CS, Sergio CM, Dinger ME, Musgrove EA, Burgess A, Caldon CE.

Cell Div. 2015 Feb 19;10:1. doi: 10.1186/s13008-015-0007-9. eCollection 2015.


lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs.

Quek XC, Thomson DW, Maag JL, Bartonicek N, Signal B, Clark MB, Gloss BS, Dinger ME.

Nucleic Acids Res. 2015 Jan;43(Database issue):D168-73. doi: 10.1093/nar/gku988. Epub 2014 Oct 20.


A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo.

Martin NP, Marron Fernandez de Velasco E, Mizuno F, Scappini EL, Gloss B, Erxleben C, Williams JG, Stapleton HM, Gentile S, Armstrong DL.

Endocrinology. 2014 Sep;155(9):3713-24. doi: 10.1210/en.2013-2058. Epub 2014 Jun 16.


Methylation-capture and Next-Generation Sequencing of free circulating DNA from human plasma.

Warton K, Lin V, Navin T, Armstrong NJ, Kaplan W, Ying K, Gloss B, Mangs H, Nair SS, Hacker NF, Sutherland RL, Clark SJ, Samimi G.

BMC Genomics. 2014 Jun 15;15:476. doi: 10.1186/1471-2164-15-476.


Optogenetic mapping of cerebellar inhibitory circuitry reveals spatially biased coordination of interneurons via electrical synapses.

Kim J, Lee S, Tsuda S, Zhang X, Asrican B, Gloss B, Feng G, Augustine GJ.

Cell Rep. 2014 Jun 12;7(5):1601-1613. doi: 10.1016/j.celrep.2014.04.047. Epub 2014 May 22.


Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations.

Leddy HA, McNulty AL, Lee SH, Rothfusz NE, Gloss B, Kirby ML, Hutson MR, Cohn DH, Guilak F, Liedtke W.

FASEB J. 2014 Jun;28(6):2525-37. doi: 10.1096/fj.13-245936. Epub 2014 Feb 27.


IL-21 contributes to fatal inflammatory disease in the absence of Foxp3+ T regulatory cells.

Vogelzang A, McGuire HM, Liu SM, Gloss B, Mercado K, Earls P, Dinger ME, Batten M, Sprent J, King C.

J Immunol. 2014 Feb 15;192(4):1404-14. doi: 10.4049/jimmunol.1302285. Epub 2014 Jan 20.


ZNF300P1 encodes a lincRNA that regulates cell polarity and is epigenetically silenced in type II epithelial ovarian cancer.

Gloss B, Moran-Jones K, Lin V, Gonzalez M, Scurry J, Hacker NF, Sutherland RL, Clark SJ, Samimi G.

Mol Cancer. 2014 Jan 6;13:3. doi: 10.1186/1476-4598-13-3.


Next-generation transgenic mice for optogenetic analysis of neural circuits.

Asrican B, Augustine GJ, Berglund K, Chen S, Chow N, Deisseroth K, Feng G, Gloss B, Hira R, Hoffmann C, Kasai H, Katarya M, Kim J, Kudolo J, Lee LM, Lo SQ, Mancuso J, Matsuzaki M, Nakajima R, Qiu L, Tan G, Tang Y, Ting JT, Tsuda S, Wen L, Zhang X, Zhao S.

Front Neural Circuits. 2013 Nov 26;7:160. doi: 10.3389/fncir.2013.00160. eCollection 2013.


Epigenetic biomarkers in epithelial ovarian cancer.

Gloss BS, Samimi G.

Cancer Lett. 2014 Jan 28;342(2):257-63. doi: 10.1016/j.canlet.2011.12.036. Epub 2012 Jan 12. Review.


Integrative genome-wide expression and promoter DNA methylation profiling identifies a potential novel panel of ovarian cancer epigenetic biomarkers.

Gloss BS, Patterson KI, Barton CA, Gonzalez M, Scurry JP, Hacker NF, Sutherland RL, O'Brien PM, Clark SJ.

Cancer Lett. 2012 May 1;318(1):76-85. doi: 10.1016/j.canlet.2011.12.003. Epub 2011 Dec 9.


Prognostic and diagnostic significance of DNA methylation patterns in high grade serous ovarian cancer.

Montavon C, Gloss BS, Warton K, Barton CA, Statham AL, Scurry JP, Tabor B, Nguyen TV, Qu W, Samimi G, Hacker NF, Sutherland RL, Clark SJ, O'Brien PM.

Gynecol Oncol. 2012 Mar;124(3):582-8. doi: 10.1016/j.ygyno.2011.11.026. Epub 2011 Nov 22.


Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function.

Zhao S, Ting JT, Atallah HE, Qiu L, Tan J, Gloss B, Augustine GJ, Deisseroth K, Luo M, Graybiel AM, Feng G.

Nat Methods. 2011 Sep;8(9):745-52.


An Improved BAC Transgenic Fluorescent Reporter Line for Sensitive and Specific Identification of Striatonigral Medium Spiny Neurons.

Ade KK, Wan Y, Chen M, Gloss B, Calakos N.

Front Syst Neurosci. 2011 Jun 8;5:32. doi: 10.3389/fnsys.2011.00032. eCollection 2011.


MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome.

Byrne JA, Maleki S, Hardy JR, Gloss BS, Murali R, Scurry JP, Fanayan S, Emmanuel C, Hacker NF, Sutherland RL, Defazio A, O'Brien PM.

BMC Cancer. 2010 Sep 17;10:497. doi: 10.1186/1471-2407-10-497.


Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival.

Barton CA, Gloss BS, Qu W, Statham AL, Hacker NF, Sutherland RL, Clark SJ, O'Brien PM.

Br J Cancer. 2010 Jan 5;102(1):87-96. doi: 10.1038/sj.bjc.6605429. Epub 2009 Nov 24.


Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.

Milone MC, Fish JD, Carpenito C, Carroll RG, Binder GK, Teachey D, Samanta M, Lakhal M, Gloss B, Danet-Desnoyers G, Campana D, Riley JL, Grupp SA, June CH.

Mol Ther. 2009 Aug;17(8):1453-64. doi: 10.1038/mt.2009.83. Epub 2009 Apr 21. Erratum in: Mol Ther. 2015 Jul;23(7):1278.


Improved expression of halorhodopsin for light-induced silencing of neuronal activity.

Zhao S, Cunha C, Zhang F, Liu Q, Gloss B, Deisseroth K, Augustine GJ, Feng G.

Brain Cell Biol. 2008 Aug;36(1-4):141-54. doi: 10.1007/s11068-008-9034-7. Epub 2008 Oct 17.


The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro.

O'Brien PM, Davies MJ, Scurry JP, Smith AN, Barton CA, Henderson MJ, Saunders DN, Gloss BS, Patterson KI, Clancy JL, Heinzelmann-Schwarz VA, Murali R, Scolyer RA, Zeng Y, Williams ED, Scurr L, Defazio A, Quinn DI, Watts CK, Hacker NF, Henshall SM, Sutherland RL.

Br J Cancer. 2008 Mar 25;98(6):1085-93. doi: 10.1038/sj.bjc.6604281. Epub 2008 Mar 18. Erratum in: Br J Cancer. 2008 Jun 3;98(11):1880. Murali, Rajmohan [added].


Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia.

Shuen JA, Chen M, Gloss B, Calakos N.

J Neurosci. 2008 Mar 12;28(11):2681-5. doi: 10.1523/JNEUROSCI.5492-07.2008. No abstract available.


In vivo gene delivery of HSP70i by adenovirus and adeno-associated virus preserves contractile function in mouse heart following ischemia-reperfusion.

Belke DD, Gloss B, Hollander JM, Swanson EA, Duplain H, Dillmann WH.

Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2905-10. Epub 2006 Aug 18.


Analysis of the regulation of viral transcription.

Gloss B, Kalantari M, Bernard HU.

Methods Mol Med. 2005;119:261-78.


Different configurations of specific thyroid hormone response elements mediate opposite effects of thyroid hormone and GC-1 on gene expression.

Gloss B, Giannocco G, Swanson EA, Moriscot AS, Chiellini G, Scanlan T, Baxter JD, Dillmann WH.

Endocrinology. 2005 Nov;146(11):4926-33. Epub 2005 Aug 4.


Doxycycline inducible expression of SERCA2a improves calcium handling and reverts cardiac dysfunction in pressure overload-induced cardiac hypertrophy.

Suarez J, Gloss B, Belke DD, Hu Y, Scott B, Dieterle T, Kim YK, Valencik ML, McDonald JA, Dillmann WH.

Am J Physiol Heart Circ Physiol. 2004 Nov;287(5):H2164-72. Epub 2004 Jul 15.


Cardiac expression and function of thyroid hormone receptor beta and its PV mutant.

Swanson EA, Gloss B, Belke DD, Kaneshige M, Cheng SY, Dillmann WH.

Endocrinology. 2003 Nov;144(11):4820-5. Epub 2003 Aug 7.


In vivo adenoviral transfer of sorcin reverses cardiac contractile abnormalities of diabetic cardiomyopathy.

Suarez J, Belke DD, Gloss B, Dieterle T, McDonough PM, Kim YK, Brunton LL, Dillmann WH.

Am J Physiol Heart Circ Physiol. 2004 Jan;286(1):H68-75. Epub 2003 Sep 4.


The role of thyroid hormone receptors in the heart.

Dillmann WH, Gloss BR.

Methods Mol Biol. 2002;202:55-70. Review. No abstract available.


Using genetically engineered mice to study myocardial ischemia-reperfusion injury.

Das DK, Dillmann W, Ho YS, Lin KM, Gloss BR.

Methods Enzymol. 2002;353:346-65. No abstract available.


Cardiac ion channel expression and contractile function in mice with deletion of thyroid hormone receptor alpha or beta.

Gloss B, Trost S, Bluhm W, Swanson E, Clark R, Winkfein R, Janzen K, Giles W, Chassande O, Samarut J, Dillmann W.

Endocrinology. 2001 Feb;142(2):544-50.


The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity.

Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann WH.

Endocrinology. 2000 Sep;141(9):3057-64.


Thyroid hormone-induced stimulation of the sarcoplasmic reticulum Ca(2+) ATPase gene is inhibited by LIF and IL-6.

Gloss B, Villegas S, Villarreal FJ, Moriscot A, Dillmann WH.

Am J Physiol Endocrinol Metab. 2000 Apr;278(4):E738-43.


Altered cardiac phenotype in transgenic mice carrying the delta337 threonine thyroid hormone receptor beta mutant derived from the S family.

Gloss B, Sayen MR, Trost SU, Bluhm WF, Meyer M, Swanson EA, Usala SJ, Dillmann WH.

Endocrinology. 1999 Feb;140(2):897-902.


A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors.

Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin SC, Heyman RA, Rose DW, Glass CK, Rosenfeld MG.

Cell. 1996 May 3;85(3):403-14.


Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor.

Hörlein AJ, Näär AM, Heinzel T, Torchia J, Gloss B, Kurokawa R, Ryan A, Kamei Y, Söderström M, Glass CK, et al.

Nature. 1995 Oct 5;377(6548):397-404.


P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1.

Bach I, Rhodes SJ, Pearse RV 2nd, Heinzel T, Gloss B, Scully KM, Sawchenko PE, Rosenfeld MG.

Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2720-4.

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