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Items: 25


Benzoxazoles, Phthalazinones, and Arylurea-Based Compounds with IMP Dehydrogenase-Independent Antibacterial Activity against Francisella tularensis.

Gorla SK, Zhang Y, Rabideau MM, Qin A, Chacko S, House AL, Johnson CR, Mandapati K, Bernstein HM, McKenney ES, Boshoff H, Zhang M, Glomski IJ, Goldberg JB, Cuny GD, Mann BJ, Hedstrom L.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00939-17. doi: 10.1128/AAC.00939-17. Print 2017 Oct.


Repurposing cryptosporidium inosine 5'-monophosphate dehydrogenase inhibitors as potential antibacterial agents.

Mandapati K, Gorla SK, House AL, McKenney ES, Zhang M, Rao SN, Gollapalli DR, Mann BJ, Goldberg JB, Cuny GD, Glomski IJ, Hedstrom L.

ACS Med Chem Lett. 2014 Jun 10;5(8):846-50. doi: 10.1021/ml500203p. eCollection 2014 Aug 14. Erratum in: ACS Med Chem Lett. 2014 Oct 9;5(10):1174.


In trans complementation of lethal factor reveal roles in colonization and dissemination in a murine mouse model.

Lowe DE, Ya J, Glomski IJ.

PLoS One. 2014 Apr 24;9(4):e95950. doi: 10.1371/journal.pone.0095950. eCollection 2014.


Circulating lethal toxin decreases the ability of neutrophils to respond to Bacillus anthracis.

Weiner ZP, Ernst SM, Boyer AE, Gallegos-Candela M, Barr JR, Glomski IJ.

Cell Microbiol. 2014 Apr;16(4):504-18. doi: 10.1111/cmi.12232. Epub 2013 Nov 6.


Bacillus anthracis has two independent bottlenecks that are dependent on the portal of entry in an intranasal model of inhalational infection.

Lowe DE, Ernst SM, Zito C, Ya J, Glomski IJ.

Infect Immun. 2013 Dec;81(12):4408-20. doi: 10.1128/IAI.00484-13. Epub 2013 Sep 16.


In vivo germination of Bacillus anthracis spores during murine cutaneous infection.

Corre JP, Piris-Gimenez A, Moya-Nilges M, Jouvion G, Fouet A, Glomski IJ, Mock M, Sirard JC, Goossens PL.

J Infect Dis. 2013 Feb 1;207(3):450-7. doi: 10.1093/infdis/jis686. Epub 2012 Nov 12.


Germination and amplification of anthrax spores by soil-dwelling amoebas.

Dey R, Hoffman PS, Glomski IJ.

Appl Environ Microbiol. 2012 Nov;78(22):8075-81. doi: 10.1128/AEM.02034-12. Epub 2012 Sep 14.


Cellular and physiological effects of anthrax exotoxin and its relevance to disease.

Lowe DE, Glomski IJ.

Front Cell Infect Microbiol. 2012 Jun 1;2:76. doi: 10.3389/fcimb.2012.00076. eCollection 2012. Review.


Debridement increases survival in a mouse model of subcutaneous anthrax.

Weiner ZP, Boyer AE, Gallegos-Candela M, Cardani AN, Barr JR, Glomski IJ.

PLoS One. 2012;7(2):e30201. doi: 10.1371/journal.pone.0030201. Epub 2012 Feb 29.


Updating perspectives on the initiation of Bacillus anthracis growth and dissemination through its host.

Weiner ZP, Glomski IJ.

Infect Immun. 2012 May;80(5):1626-33. doi: 10.1128/IAI.06061-11. Epub 2012 Feb 21. Review.


Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis.

Crawford MA, Lowe DE, Fisher DJ, Stibitz S, Plaut RD, Beaber JW, Zemansky J, Mehrad B, Glomski IJ, Strieter RM, Hughes MA.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17159-64. doi: 10.1073/pnas.1108495108. Epub 2011 Sep 26.


Noninvasive imaging technologies reveal edema toxin as a key virulence factor in anthrax.

Dumetz F, Jouvion G, Khun H, Glomski IJ, Corre JP, Rougeaux C, Tang WJ, Mock M, Huerre M, Goossens PL.

Am J Pathol. 2011 Jun;178(6):2523-35. doi: 10.1016/j.ajpath.2011.02.027.


Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis.

Klimecka MM, Chruszcz M, Font J, Skarina T, Shumilin I, Onopryienko O, Porebski PJ, Cymborowski M, Zimmerman MD, Hasseman J, Glomski IJ, Lebioda L, Savchenko A, Edwards A, Minor W.

J Mol Biol. 2011 Jul 15;410(3):411-23. doi: 10.1016/j.jmb.2011.04.076. Epub 2011 May 13.


Immunological alterations mediated by adenosine during host-microbial interactions.

Drygiannakis I, Ernst PB, Lowe D, Glomski IJ.

Immunol Res. 2011 May;50(1):69-77. doi: 10.1007/s12026-011-8207-0. Review.


Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection.

Crawford MA, Burdick MD, Glomski IJ, Boyer AE, Barr JR, Mehrad B, Strieter RM, Hughes MA.

PLoS Pathog. 2010 Nov 18;6(11):e1001199. doi: 10.1371/journal.ppat.1001199.


Comparative analysis of the virulence of invertebrate and mammalian pathogenic bacteria in the oral insect infection model Galleria mellonella.

Fedhila S, Buisson C, Dussurget O, Serror P, Glomski IJ, Liehl P, Lereclus D, Nielsen-LeRoux C.

J Invertebr Pathol. 2010 Jan;103(1):24-9. doi: 10.1016/j.jip.2009.09.005. Epub 2009 Oct 1.


Inhaled non-capsulated Bacillus anthracis in A/J mice: nasopharynx and alveolar space as dual portals of entry, delayed dissemination, and specific organ targeting.

Glomski IJ, Dumetz F, Jouvion G, Huerre MR, Mock M, Goossens PL.

Microbes Infect. 2008 Oct;10(12-13):1398-404. doi: 10.1016/j.micinf.2008.07.042. Epub 2008 Aug 13.


Primary involvement of pharynx and peyer's patch in inhalational and intestinal anthrax.

Glomski IJ, Piris-Gimenez A, Huerre M, Mock M, Goossens PL.

PLoS Pathog. 2007 Jun;3(6):e76.


Murine splenocytes produce inflammatory cytokines in a MyD88-dependent response to Bacillus anthracis spores.

Glomski IJ, Fritz JH, Keppler SJ, Balloy V, Chignard M, Mock M, Goossens PL.

Cell Microbiol. 2007 Feb;9(2):502-13. Epub 2006 Sep 18.


Regulated translation of listeriolysin O controls virulence of Listeria monocytogenes.

Schnupf P, Hofmann J, Norseen J, Glomski IJ, Schwartzstein H, Decatur AL.

Mol Microbiol. 2006 Aug;61(4):999-1012. Epub 2006 Jul 12.


The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity.

Portnoy DA, Auerbuch V, Glomski IJ.

J Cell Biol. 2002 Aug 5;158(3):409-14. Epub 2002 Aug 5. Review.


The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells.

Glomski IJ, Gedde MM, Tsang AW, Swanson JA, Portnoy DA.

J Cell Biol. 2002 Mar 18;156(6):1029-38. Epub 2002 Mar 18.

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