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Items: 1 to 50 of 113

1.

Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity.

Chun E, Lavoie S, Fonseca-Pereira D, Bae S, Michaud M, Hoveyda HR, Fraser GL, Gallini Comeau CA, Glickman JN, Fuller MH, Layden BT, Garrett WS.

Immunity. 2019 Nov 19;51(5):871-884.e6. doi: 10.1016/j.immuni.2019.09.014. Epub 2019 Oct 15.

PMID:
31628054
2.

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response.

Grootjans J, Krupka N, Hosomi S, Matute JD, Hanley T, Saveljeva S, Gensollen T, Heijmans J, Li H, Limenitakis JP, Ganal-Vonarburg SC, Suo S, Luoma AM, Shimodaira Y, Duan J, Shih DQ, Conner ME, Glickman JN, Fuhler GM, Palm NW, de Zoete MR, van der Woude CJ, Yuan GC, Wucherpfennig KW, Targan SR, Rosenstiel P, Flavell RA, McCoy KD, Macpherson AJ, Kaser A, Blumberg RS.

Science. 2019 Mar 1;363(6430):993-998. doi: 10.1126/science.aat7186.

3.

The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response.

Lavoie S, Conway KL, Lassen KG, Jijon HB, Pan H, Chun E, Michaud M, Lang JK, Gallini Comeau CA, Dreyfuss JM, Glickman JN, Vlamakis H, Ananthakrishnan A, Kostic A, Garrett WS, Xavier RJ.

Elife. 2019 Jan 22;8. pii: e39982. doi: 10.7554/eLife.39982.

4.

SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance.

Wasserman I, Lee LH, Ogino S, Marco MR, Wu C, Chen X, Datta J, Sadot E, Szeglin B, Guillem JG, Paty PB, Weiser MR, Nash GM, Saltz L, Barlas A, Manova-Todorova K, Uppada SPB, Elghouayel AE, Ntiamoah P, Glickman JN, Hamada T, Kosumi K, Inamura K, Chan AT, Nishihara R, Cercek A, Ganesh K, Kemeny NE, Dhawan P, Yaeger R, Sawyers CL, Garcia-Aguilar J, Giannakis M, Shia J, Smith JJ.

Clin Cancer Res. 2019 Mar 15;25(6):1948-1956. doi: 10.1158/1078-0432.CCR-18-1726. Epub 2018 Dec 26.

PMID:
30587545
5.

TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PD-L1) expression status and tumor-infiltrating lymphocytes in colorectal carcinomas.

Hamada T, Soong TR, Masugi Y, Kosumi K, Nowak JA, da Silva A, Mu XJ, Twombly TS, Koh H, Yang J, Song M, Liu L, Gu M, Shi Y, Nosho K, Morikawa T, Inamura K, Shukla SA, Wu CJ, Garraway LA, Zhang X, Wu K, Meyerhardt JA, Chan AT, Glickman JN, Rodig SJ, Freeman GJ, Fuchs CS, Nishihara R, Giannakis M, Ogino S.

Oncoimmunology. 2018 Mar 19;7(7):e1442999. doi: 10.1080/2162402X.2018.1442999. eCollection 2018.

6.

Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation.

Hosomi S, Grootjans J, Tschurtschenthaler M, Krupka N, Matute JD, Flak MB, Martinez-Naves E, Gomez Del Moral M, Glickman JN, Ohira M, Lanier LL, Kaser A, Blumberg R.

J Exp Med. 2017 Oct 2;214(10):2985-2997. doi: 10.1084/jem.20162041. Epub 2017 Jul 26.

7.

QseC inhibition as an antivirulence approach for colitis-associated bacteria.

Rooks MG, Veiga P, Reeves AZ, Lavoie S, Yasuda K, Asano Y, Yoshihara K, Michaud M, Wardwell-Scott L, Gallini CA, Glickman JN, Sudo N, Huttenhower C, Lesser CF, Garrett WS.

Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):142-147. doi: 10.1073/pnas.1612836114. Epub 2016 Dec 15.

8.

Crohn's disease Activity: Abdominal Computed Tomography Histopathology Correlation.

Paquet N, Glickman JN, Erturk SM, Ros PR, Heverhagen JT, Patak MA.

Eur J Radiol Open. 2016 Apr 11;3:74-78. eCollection 2016.

9.

Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS.

Nature. 2016 Aug 18;536(7616):359. doi: 10.1038/nature17421. Epub 2016 Mar 16. No abstract available.

10.

An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease.

Zhang S, Ermann J, Succi MD, Zhou A, Hamilton MJ, Cao B, Korzenik JR, Glickman JN, Vemula PK, Glimcher LH, Traverso G, Langer R, Karp JM.

Sci Transl Med. 2015 Aug 12;7(300):300ra128. doi: 10.1126/scitranslmed.aaa5657.

11.

CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function.

Chun E, Lavoie S, Michaud M, Gallini CA, Kim J, Soucy G, Odze R, Glickman JN, Garrett WS.

Cell Rep. 2015 Jul 14;12(2):244-57. doi: 10.1016/j.celrep.2015.06.024. Epub 2015 Jul 2.

12.

Host lysozyme-mediated lysis of Lactococcus lactis facilitates delivery of colitis-attenuating superoxide dismutase to inflamed colons.

Ballal SA, Veiga P, Fenn K, Michaud M, Kim JH, Gallini CA, Glickman JN, Quéré G, Garault P, Béal C, Derrien M, Courtin P, Kulakauskas S, Chapot-Chartier MP, van Hylckama Vlieg J, Garrett WS.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7803-8. doi: 10.1073/pnas.1501897112. Epub 2015 Jun 8.

13.

Helicobacter infections with rare bacteria or minimal gastritis: Expecting the unexpected.

Glickman JN, Noffsinger A, Nevin DT, Ray M, Lash RH, Genta RM.

Dig Liver Dis. 2015 Jul;47(7):549-55. doi: 10.1016/j.dld.2015.04.005. Epub 2015 Apr 30.

PMID:
26003395
14.

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS.

Nature. 2015 Jan 15;517(7534):386-90. doi: 10.1038/nature13848. Epub 2014 Oct 26. Erratum in: Nature. 2016 Aug 18;536(7616):359.

15.

Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice.

Ermann J, Staton T, Glickman JN, de Waal Malefyt R, Glimcher LH.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2559-66. doi: 10.1073/pnas.1408540111. Epub 2014 Jun 9.

16.

Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission.

Rooks MG, Veiga P, Wardwell-Scott LH, Tickle T, Segata N, Michaud M, Gallini CA, Beal C, van Hylckama-Vlieg JE, Ballal SA, Morgan XC, Glickman JN, Gevers D, Huttenhower C, Garrett WS.

ISME J. 2014 Jul;8(7):1403-17. doi: 10.1038/ismej.2014.3. Epub 2014 Feb 6.

17.

Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer.

Baker K, Rath T, Flak MB, Arthur JC, Chen Z, Glickman JN, Zlobec I, Karamitopoulou E, Stachler MD, Odze RD, Lencer WI, Jobin C, Blumberg RS.

Immunity. 2013 Dec 12;39(6):1095-107. doi: 10.1016/j.immuni.2013.11.003. Epub 2013 Nov 27.

18.

Paneth cells as a site of origin for intestinal inflammation.

Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS.

Nature. 2013 Nov 14;503(7475):272-6. doi: 10.1038/nature12599. Epub 2013 Oct 2.

19.

Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment.

Kostic AD, Chun E, Robertson L, Glickman JN, Gallini CA, Michaud M, Clancy TE, Chung DC, Lochhead P, Hold GL, El-Omar EM, Brenner D, Fuchs CS, Meyerson M, Garrett WS.

Cell Host Microbe. 2013 Aug 14;14(2):207-15. doi: 10.1016/j.chom.2013.07.007.

20.

The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis.

Smith PM, Howitt MR, Panikov N, Michaud M, Gallini CA, Bohlooly-Y M, Glickman JN, Garrett WS.

Science. 2013 Aug 2;341(6145):569-73. doi: 10.1126/science.1241165. Epub 2013 Jul 4.

21.

Microbial exposure during early life has persistent effects on natural killer T cell function.

Olszak T, An D, Zeissig S, Vera MP, Richter J, Franke A, Glickman JN, Siebert R, Baron RM, Kasper DL, Blumberg RS.

Science. 2012 Apr 27;336(6080):489-93. doi: 10.1126/science.1219328. Epub 2012 Mar 22.

22.

Imaging features of bone metastases in patients with gastrointestinal stromal tumors.

Jati A, Tatlı S, Morgan JA, Glickman JN, Demetri GD, Van den Abbele A, Silverman SG.

Diagn Interv Radiol. 2012 Jul-Aug;18(4):391-6. doi: 10.4261/1305-3825.DIR.5179-11.1. Epub 2012 Mar 9.

23.

Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus.

Ermann J, Garrett WS, Kuchroo J, Rourida K, Glickman JN, Bleich A, Glimcher LH.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7137-41. doi: 10.1073/pnas.1104234108. Epub 2011 Apr 11.

24.

Essential role for mast cell tryptase in acute experimental colitis.

Hamilton MJ, Sinnamon MJ, Lyng GD, Glickman JN, Wang X, Xing W, Krilis SA, Blumberg RS, Adachi R, Lee DM, Stevens RL.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):290-5. doi: 10.1073/pnas.1005758108. Epub 2010 Dec 20.

25.

Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes.

Veiga P, Gallini CA, Beal C, Michaud M, Delaney ML, DuBois A, Khlebnikov A, van Hylckama Vlieg JE, Punit S, Glickman JN, Onderdonk A, Glimcher LH, Garrett WS.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18132-7. doi: 10.1073/pnas.1011737107. Epub 2010 Oct 4. Erratum in: Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21943.

26.

Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis.

Garrett WS, Gallini CA, Yatsunenko T, Michaud M, DuBois A, Delaney ML, Punit S, Karlsson M, Bry L, Glickman JN, Gordon JI, Onderdonk AB, Glimcher LH.

Cell Host Microbe. 2010 Sep 16;8(3):292-300. doi: 10.1016/j.chom.2010.08.004.

27.

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

Mueller SN, Vanguri VK, Ha SJ, West EE, Keir ME, Glickman JN, Sharpe AH, Ahmed R.

J Clin Invest. 2010 Jul;120(7):2508-15. doi: 10.1172/JCI40040. Epub 2010 Jun 14.

28.

Pathophysiological preconditions promoting mixed "black" pigment plus cholesterol gallstones in a DeltaF508 mouse model of cystic fibrosis.

Freudenberg F, Leonard MR, Liu SA, Glickman JN, Carey MC.

Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G205-14. doi: 10.1152/ajpgi.00341.2009. Epub 2010 Apr 29.

29.

Clinical predictors of hepatic fibrosis in chronic advanced heart failure.

Gelow JM, Desai AS, Hochberg CP, Glickman JN, Givertz MM, Fang JC.

Circ Heart Fail. 2010 Jan;3(1):59-64. doi: 10.1161/CIRCHEARTFAILURE.109.872556. Epub 2009 Oct 14.

PMID:
19828874
30.

Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.

Ogino S, Nosho K, Irahara N, Meyerhardt JA, Baba Y, Shima K, Glickman JN, Ferrone CR, Mino-Kenudson M, Tanaka N, Dranoff G, Giovannucci EL, Fuchs CS.

Clin Cancer Res. 2009 Oct 15;15(20):6412-20. doi: 10.1158/1078-0432.CCR-09-1438. Epub 2009 Oct 13.

31.

Variability of histopathological changes in childhood celiac disease.

Weir DC, Glickman JN, Roiff T, Valim C, Leichtner AM.

Am J Gastroenterol. 2010 Jan;105(1):207-12. doi: 10.1038/ajg.2009.557. Epub 2009 Oct 6.

PMID:
19809405
32.

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells.

Garrett WS, Punit S, Gallini CA, Michaud M, Zhang D, Sigrist KS, Lord GM, Glickman JN, Glimcher LH.

Cancer Cell. 2009 Sep 8;16(3):208-19. doi: 10.1016/j.ccr.2009.07.015.

33.

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP.

Nat Med. 2009 Aug;15(8):940-5. doi: 10.1038/nm.1994. Epub 2009 Jul 26.

34.

Renal cell carcinoma: t1 and t2 signal intensity characteristics of papillary and clear cell types correlated with pathology.

Oliva MR, Glickman JN, Zou KH, Teo SY, Mortelé KJ, Rocha MS, Silverman SG.

AJR Am J Roentgenol. 2009 Jun;192(6):1524-30. doi: 10.2214/AJR.08.1727.

PMID:
19457814
35.

Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma.

Gordon GJ, Dong L, Yeap BY, Richards WG, Glickman JN, Edenfield H, Mani M, Colquitt R, Maulik G, Van Oss B, Sugarbaker DJ, Bueno R.

J Natl Cancer Inst. 2009 May 6;101(9):678-86. doi: 10.1093/jnci/djp061. Epub 2009 Apr 28.

36.

Matrix metalloproteinases in the urine and tissue of patients with juvenile polyps: potential biomarkers for the presence of polyps.

Manfredi MA, Fox VL, Zurakowski D, Kutok JL, Glickman JN, Moses MA.

J Pediatr Gastroenterol Nutr. 2009 Apr;48(4):405-11.

37.

Multilayered epithelium in mucosal biopsy specimens from the gastroesophageal junction region is a histologic marker of gastroesophageal reflux disease.

Glickman JN, Spechler SJ, Souza RF, Lunsford T, Lee E, Odze RD.

Am J Surg Pathol. 2009 Jun;33(6):818-25. doi: 10.1097/PAS.0b013e3181984697.

PMID:
19295405
38.

An unusual mixed tumor of the pancreas: sonographic and MDCT features.

Mortelé KJ, Peters HE, Odze RD, Glickman JN, Jajoo K, Banks PA.

JOP. 2009 Mar 9;10(2):204-8.

39.

Clinical significance of colonic intraepithelial lymphocytosis in a pediatric population.

Najarian RM, Hait EJ, Leichtner AM, Glickman JN, Antonioli DA, Goldsmith JD.

Mod Pathol. 2009 Jan;22(1):13-20. doi: 10.1038/modpathol.2008.139. Epub 2008 Sep 5.

40.

Acute appendicitis is characterized by a uniform and highly selective pattern of inflammatory gene expression.

Murphy CG, Glickman JN, Tomczak K, Wang YY, Beggs AH, Shannon MW, Horwitz BH.

Mucosal Immunol. 2008 Jul;1(4):297-308. doi: 10.1038/mi.2008.13.

41.

Pancreatic intraductal papillary mucinous neoplasms: role of CT in predicting pathologic subtypes.

Gupta R, Mortelé KJ, Tatli S, Girshman J, Glickman JN, Levy AD, Erturk SM, Heffess CS, Banks PA, Silverman SG.

AJR Am J Roentgenol. 2008 Nov;191(5):1458-64. doi: 10.2214/AJR.07.3302. Erratum in: AJR Am J Roentgenol. 2008 Dec;191(6):1876.

PMID:
18941085
42.

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A, Gupta S, Moore J, Wrobel MJ, Lerner J, Reich M, Chan JA, Glickman JN, Ikeda K, Hashimoto M, Watanabe G, Daidone MG, Roayaie S, Schwartz M, Thung S, Salvesen HB, Gabriel S, Mazzaferro V, Bruix J, Friedman SL, Kumada H, Llovet JM, Golub TR.

N Engl J Med. 2008 Nov 6;359(19):1995-2004. doi: 10.1056/NEJMoa0804525. Epub 2008 Oct 15.

43.

Allogeneic transplantation successfully corrects immune defects, but not susceptibility to colitis, in a patient with nuclear factor-kappaB essential modulator deficiency.

Pai SY, Levy O, Jabara HH, Glickman JN, Stoler-Barak L, Sachs J, Nurko S, Orange JS, Geha RS.

J Allergy Clin Immunol. 2008 Dec;122(6):1113-1118.e1. doi: 10.1016/j.jaci.2008.08.026. Epub 2008 Oct 11.

44.

Reduction of inflammation and chronic tissue damage by omega-3 fatty acids in fat-1 transgenic mice with pancreatitis.

Weylandt KH, Nadolny A, Kahlke L, Köhnke T, Schmöcker C, Wang J, Lauwers GY, Glickman JN, Kang JX.

Biochim Biophys Acta. 2008 Nov;1782(11):634-41. doi: 10.1016/j.bbadis.2008.08.011. Epub 2008 Sep 12.

45.

Does rectal sparing ever occur in ulcerative colitis?

Glickman JN, Odze RD.

Inflamm Bowel Dis. 2008 Oct;14 Suppl 2:S166-7. doi: 10.1002/ibd.20592. No abstract available. Erratum in: Inflamm Bowel Dis. 2009 Sep;15(9):1438-47.

PMID:
18816786
46.

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.

Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, Blumberg RS.

Cell. 2008 Sep 5;134(5):743-56. doi: 10.1016/j.cell.2008.07.021.

47.

Cholangiocyte bile salt transporters in cholesterol gallstone-susceptible and resistant inbred mouse strains.

Liu JJ, Glickman JN, Masyuk AI, Larusso NF.

J Gastroenterol Hepatol. 2008 Oct;23(10):1596-602. doi: 10.1111/j.1440-1746.2008.05500.x. Epub 2008 Aug 20.

48.

Pathophysiological basis of liver disease in cystic fibrosis employing a DeltaF508 mouse model.

Freudenberg F, Broderick AL, Yu BB, Leonard MR, Glickman JN, Carey MC.

Am J Physiol Gastrointest Liver Physiol. 2008 Jun;294(6):G1411-20. doi: 10.1152/ajpgi.00181.2007. Epub 2008 Apr 24.

49.

Resolving the three-dimensional myoarchitecture of bovine esophageal wall with diffusion spectrum imaging and tractography.

Gilbert RJ, Gaige TA, Wang R, Benner T, Dai G, Glickman JN, Wedeen VJ.

Cell Tissue Res. 2008 Jun;332(3):461-8. doi: 10.1007/s00441-008-0601-0. Epub 2008 Apr 10.

PMID:
18401597
50.

Ulcerative colitis surveillance: activity does matter.

Glickman JN.

Inflamm Bowel Dis. 2008 Oct;14(10):1453-4. doi: 10.1002/ibd.20468. No abstract available.

PMID:
18393374

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