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Items: 1 to 50 of 62

1.

Retrodifferentiation of Human Tumor Hepatocytes to Stem Cells Leads to Metabolic Reprogramming and Chemoresistance.

Fekir K, Dubois-Pot-Schneider H, Désert R, Daniel Y, Glaise D, Rauch C, Morel F, Fromenty B, Musso O, Cabillic F, Corlu A.

Cancer Res. 2019 Apr 15;79(8):1869-1883. doi: 10.1158/0008-5472.CAN-18-2110. Epub 2019 Mar 5.

PMID:
30837223
2.

Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate-treated hepatocyte and stellate cell.

Dornas W, Glaise D, Bodin A, Sharanek A, Burban A, Le Guillou D, Robert S, Dutertre S, Aninat C, Corlu A, Lagente V.

J Cell Physiol. 2018 Jan;234(1):122-133. doi: 10.1002/jcp.27175. Epub 2018 Sep 7.

PMID:
30191979
3.

TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors.

Ancey PB, Ecsedi S, Lambert MP, Talukdar FR, Cros MP, Glaise D, Narvaez DM, Chauvet V, Herceg Z, Corlu A, Hernandez-Vargas H.

Stem Cell Reports. 2017 Jul 11;9(1):264-278. doi: 10.1016/j.stemcr.2017.05.023. Epub 2017 Jun 22.

4.

Evaluation of genotoxicity using automated detection of γH2AX in metabolically competent HepaRG cells.

Quesnot N, Rondel K, Audebert M, Martinais S, Glaise D, Morel F, Loyer P, Robin MA.

Mutagenesis. 2016 Jan;31(1):43-50. doi: 10.1093/mutage/gev059. Epub 2015 Aug 17.

PMID:
26282955
5.

Inflammatory cytokines promote the retrodifferentiation of tumor-derived hepatocyte-like cells to progenitor cells.

Dubois-Pot-Schneider H, Fekir K, Coulouarn C, Glaise D, Aninat C, Jarnouen K, Le Guével R, Kubo T, Ishida S, Morel F, Corlu A.

Hepatology. 2014 Dec;60(6):2077-90. doi: 10.1002/hep.27353. Epub 2014 Oct 29.

PMID:
25098666
6.

Highly efficient SiRNA and gene transfer into hepatocyte-like HepaRG cells and primary human hepatocytes: new means for drug metabolism and toxicity studies.

Laurent V, Glaise D, Nübel T, Gilot D, Corlu A, Loyer P.

Methods Mol Biol. 2013;987:295-314. doi: 10.1007/978-1-62703-321-3_25.

PMID:
23475687
7.

Hepatocyte-stellate cell cross-talk in the liver engenders a permissive inflammatory microenvironment that drives progression in hepatocellular carcinoma.

Coulouarn C, Corlu A, Glaise D, Guénon I, Thorgeirsson SS, Clément B.

Cancer Res. 2012 May 15;72(10):2533-42. doi: 10.1158/0008-5472.CAN-11-3317. Epub 2012 Mar 14.

8.

CYP4F3B expression is associated with differentiation of HepaRG human hepatocytes and unaffected by fatty acid overload.

Madec S, Cerec V, Plée-Gautier E, Antoun J, Glaise D, Salaun JP, Guguen-Guillouzo C, Corlu A.

Drug Metab Dispos. 2011 Oct;39(10):1987-96. doi: 10.1124/dmd.110.036848. Epub 2011 Jul 21.

PMID:
21778351
9.

Automated detection of hepatotoxic compounds in human hepatocytes using HepaRG cells and image-based analysis of mitochondrial dysfunction with JC-1 dye.

Pernelle K, Le Guevel R, Glaise D, Stasio CG, Le Charpentier T, Bouaita B, Corlu A, Guguen-Guillouzo C.

Toxicol Appl Pharmacol. 2011 Aug 1;254(3):256-66. doi: 10.1016/j.taap.2011.04.018. Epub 2011 May 4.

PMID:
21569786
10.

The application of 3D micropatterning of agarose substrate for cell culture and in situ comet assays.

Mercey E, Obeïd P, Glaise D, Calvo-Muñoz ML, Guguen-Guillouzo C, Fouqué B.

Biomaterials. 2010 Apr;31(12):3156-65. doi: 10.1016/j.biomaterials.2010.01.020. Epub 2010 Feb 10.

PMID:
20149429
11.

Drug-metabolising enzymes are down-regulated by hypoxia in differentiated human hepatoma HepaRG cells: HIF-1alpha involvement in CYP3A4 repression.

Legendre C, Hori T, Loyer P, Aninat C, Ishida S, Glaise D, Lucas-Clerc C, Boudjema K, Guguen-Guillouzo C, Corlu A, Morel F.

Eur J Cancer. 2009 Nov;45(16):2882-92. doi: 10.1016/j.ejca.2009.07.010. Epub 2009 Aug 18.

PMID:
19695866
12.

Cytotoxic evaluation of sarcodifurines A and B, two novel dihydrofuroquinolines from Sarcomelicope follicularis (Rutaceae).

Chosson E, Guguen-Guillouzo C, Glaise D, Picot L, Seguin E, Besson T.

J Enzyme Inhib Med Chem. 2008 Oct;23(5):704-7. doi: 10.1080/14756360802208111 .

PMID:
18608759
13.

Long-term functional stability of human HepaRG hepatocytes and use for chronic toxicity and genotoxicity studies.

Jossé R, Aninat C, Glaise D, Dumont J, Fessard V, Morel F, Poul JM, Guguen-Guillouzo C, Guillouzo A.

Drug Metab Dispos. 2008 Jun;36(6):1111-8. doi: 10.1124/dmd.107.019901. Epub 2008 Mar 17.

PMID:
18347083
14.

Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor.

Cerec V, Glaise D, Garnier D, Morosan S, Turlin B, Drenou B, Gripon P, Kremsdorf D, Guguen-Guillouzo C, Corlu A.

Hepatology. 2007 Apr;45(4):957-67.

PMID:
17393521
15.

The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.

Guillouzo A, Corlu A, Aninat C, Glaise D, Morel F, Guguen-Guillouzo C.

Chem Biol Interact. 2007 May 20;168(1):66-73. Epub 2006 Dec 16. Review.

PMID:
17241619
16.

Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis.

Zindy PJ, L'Helgoualc'h A, Bonnier D, Le Béchec A, Bourd-Boitin K, Zhang CX, Musso O, Glaise D, Troadec MB, Loréal O, Turlin B, Léger J, Clément B, Théret N.

Hepatology. 2006 Nov;44(5):1296-307.

PMID:
17058241
17.

Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line.

Le Vee M, Jigorel E, Glaise D, Gripon P, Guguen-Guillouzo C, Fardel O.

Eur J Pharm Sci. 2006 May;28(1-2):109-17. Epub 2006 Feb 20.

PMID:
16488578
18.

Hepatocyte iron loading capacity is associated with differentiation and repression of motility in the HepaRG cell line.

Troadec MB, Glaise D, Lamirault G, Le Cunff M, Guérin E, Le Meur N, Détivaud L, Zindy P, Leroyer P, Guisle I, Duval H, Gripon P, Théret N, Boudjema K, Guguen-Guillouzo C, Brissot P, Léger JJ, Loréal O.

Genomics. 2006 Jan;87(1):93-103. Epub 2005 Dec 1.

19.

Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.

Aninat C, Piton A, Glaise D, Le Charpentier T, Langouët S, Morel F, Guguen-Guillouzo C, Guillouzo A.

Drug Metab Dispos. 2006 Jan;34(1):75-83. Epub 2005 Oct 4.

PMID:
16204462
20.

TNFalpha-mediated extracellular matrix remodeling is required for multiple division cycles in rat hepatocytes.

Sérandour AL, Loyer P, Garnier D, Courselaud B, Théret N, Glaise D, Guguen-Guillouzo C, Corlu A.

Hepatology. 2005 Mar;41(3):478-86.

PMID:
15723438
21.

Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth.

Ilyin GP, Glaise D, Gilot D, Baffet G, Guguen-Guillouzo C.

Am J Physiol Gastrointest Liver Physiol. 2003 Jul;285(1):G115-27. Epub 2003 Mar 19.

22.

Infection of a human hepatoma cell line by hepatitis B virus.

Gripon P, Rumin S, Urban S, Le Seyec J, Glaise D, Cannie I, Guyomard C, Lucas J, Trepo C, Guguen-Guillouzo C.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15655-60. Epub 2002 Nov 13.

23.

A new subfamily of structurally related human F-box proteins.

Ilyin GP, Sérandour AL, Pigeon C, Rialland M, Glaise D, Guguen-Guillouzo C.

Gene. 2002 Aug 21;296(1-2):11-20.

PMID:
12383498
24.

Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S-transferase regulation.

Gilot D, Loyer P, Corlu A, Glaise D, Lagadic-Gossmann D, Atfi A, Morel F, Ichijo H, Guguen-Guillouzo C.

J Biol Chem. 2002 Dec 20;277(51):49220-9. Epub 2002 Oct 4.

25.

Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations.

Rescan C, Coutant A, Talarmin H, Theret N, Glaise D, Guguen-Guillouzo C, Baffet G.

Mol Biol Cell. 2001 Mar;12(3):725-38.

26.

Expression and induction of a large set of drug-metabolizing enzymes by the highly differentiated human hepatoma cell line BC2.

Gómez-Lechón MJ, Donato T, Jover R, Rodriguez C, Ponsoda X, Glaise D, Castell JV, Guguen-Guillouzo C.

Eur J Biochem. 2001 Mar;268(5):1448-59.

27.

Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines.

Rakba N, Loyer P, Gilot D, Delcros JG, Glaise D, Baret P, Pierre JL, Brissot P, Lescoat G.

Carcinogenesis. 2000 May;21(5):943-51.

PMID:
10783316
28.

Identification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeats.

Ilyin GP, Rialland M, Glaise D, Guguen-Guillouzo C.

FEBS Lett. 1999 Oct 1;459(1):75-9.

29.

Primary cultures of heart cells from the scallop Pecten maximus (mollusca-bivalvia).

Le Marrec-Croq F, Glaise D, Guguen-Guillouzo C, Chesne C, Guillouzo A, Boulo V, Dorange G.

In Vitro Cell Dev Biol Anim. 1999 May;35(5):289-95.

PMID:
10475275
30.
31.

Skp2 induction and phosphorylation is associated with the late G1 phase of proliferating rat hepatocytes.

Bilodeau M, Talarmin H, Ilyin G, Rescan C, Glaise D, Cariou S, Loyer P, Guguen-Guillouzo C, Baffet G.

FEBS Lett. 1999 Jun 11;452(3):247-53.

32.

Cell cycle gene regulation in reversibly differentiated new human hepatoma cell lines.

Glaise D, Ilyin GP, Loyer P, Cariou S, Bilodeau M, Lucas J, Puisieux A, Ozturk M, Guguen-Guillouzo C.

Cell Growth Differ. 1998 Feb;9(2):165-76.

33.

Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP2B in rat liver and rat hepatocytes in culture.

Langouët S, Mahéo K, Berthou F, Morel F, Lagadic-Gossman D, Glaise D, Coles B, Ketterer B, Guillouzo A.

Carcinogenesis. 1997 Jul;18(7):1343-9.

PMID:
9230277
34.

Regulation of the major detoxication functions by phenobarbital and 3-methylcholanthrene in co-cultures of rat hepatocytes and liver epithelial cells.

Lerche C, Fautrel A, Shaw PM, Glaise D, Ballet F, Guillouzo A, Corcos L.

Eur J Biochem. 1997 Feb 15;244(1):98-106.

35.

trans-Acting factors, detoxication enzymes and hepatitis B virus replication in a novel set of human hepatoma cell lines.

Le Jossic C, Glaise D, Corcos L, Diot C, Dezier JF, Fautrel A, Guguen-Guillouzo C.

Eur J Biochem. 1996 Jun 1;238(2):400-9.

36.

Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1.

Loyer P, Cariou S, Glaise D, Bilodeau M, Baffet G, Guguen-Guillouzo C.

J Biol Chem. 1996 May 10;271(19):11484-92.

37.

Progression through G1 and S phases of adult rat hepatocytes.

Loyer P, Ilyin G, Cariou S, Glaise D, Corlu A, Guguen-Guillouzo C.

Prog Cell Cycle Res. 1996;2:37-47. Review.

PMID:
9552381
38.

Evidence for a role of insulin in hepatocytic differentiation of human hepatoma BC1 cells.

Kang-Park S, Capeau J, Munier A, Caron M, Glaise D, Guguen-Guillouzo C, Cherqui G, Lascols O.

Endocrine. 1995 Sep;3(9):653-60. doi: 10.1007/BF02746341.

PMID:
21153223
39.

Expression of helix-loop-helix factor Id-1 is dependent on the hepatocyte proliferation and differentiation status in rat liver and in primary culture.

Le Jossic C, Ilyin GP, Loyer P, Glaise D, Cariou S, Guguen-Guillouzo C.

Cancer Res. 1994 Dec 1;54(23):6065-8.

40.

Expression and activation of cdks (1 and 2) and cyclins in the cell cycle progression during liver regeneration.

Loyer P, Glaise D, Cariou S, Baffet G, Meijer L, Guguen-Guillouzo C.

J Biol Chem. 1994 Jan 28;269(4):2491-500.

41.

Constitutive expression of functional P-glycoprotein in rat hepatoma cells.

Fardel O, Loyer P, Lecureur V, Glaise D, Guillouzo A.

Eur J Biochem. 1994 Jan 15;219(1-2):521-8.

42.

A plasma membrane protein is involved in cell contact-mediated regulation of tissue-specific genes in adult hepatocytes.

Corlu A, Kneip B, Lhadi C, Leray G, Glaise D, Baffet G, Bourel D, Guguen-Guillouzo C.

J Cell Biol. 1991 Oct;115(2):505-15.

43.

Metabolism of doxorubicin, daunorubicin and epirubicin in human and rat hepatoma cells.

Le Bot MA, Glaise D, Kernaleguen D, Ratanasavanh D, Carlhant D, Riche C, Guillouzo A.

Pharmacol Res. 1991 Oct;24(3):243-52.

PMID:
1659695
44.

Distinct effects of cell-cell communication and corticosteroids on the synthesis and distribution of cytokeratins in cultured rat hepatocytes.

Baffet G, Loyer P, Glaise D, Corlu A, Etienne PL, Guguen-Guillouzo C.

J Cell Sci. 1991 Jul;99 ( Pt 3):609-15.

45.

Expression of laminin and its receptor LBP-32 in human and rat hepatoma cells.

Rescan PY, Clement B, Yamada Y, Glaise D, Segui-Real B, Guguen-Guillouzo C, Guillouzo A.

Hepatology. 1991 Feb;13(2):289-96.

PMID:
1847349
46.

Glutathione transferase isoenzymes in cultured rat hepatocytes.

Vandenberghe Y, Glaise D, Meyer DJ, Guillouzo A, Ketterer B.

Biochem Pharmacol. 1988 Jun 15;37(12):2482-5. No abstract available.

PMID:
3390211
47.

Influence of medium composition and culture conditions on glutathione S-transferase activity in adult rat hepatocytes during culture.

Vandenberghe Y, Ratanasavanh D, Glaise D, Guillouzo A.

In Vitro Cell Dev Biol. 1988 Apr;24(4):281-8.

PMID:
2966795
48.

Transient expression of c-fos and constant expression of c-myc in freshly isolated and cultured normal adult rat hepatocytes.

Etienne PL, Baffet G, Desvergne B, Boisnard-Rissel M, Glaise D, Guguen-Guillouzo C.

Oncogene Res. 1988;3(3):255-62.

PMID:
3144696
49.

Isolation and characterization of complementary DNA clones for genes overexpressed in chemically induced rat hepatomas.

Corral M, Defer N, Paris B, Raymondjean M, Corcos D, Tichonicky L, Kruh J, Glaise D, Kneip B, Guguen-Guillouzo C.

Cancer Res. 1986 Oct;46(10):5119-24.

50.

Dependence of hepatocyte-specific gene expression on cell-cell interactions in primary culture.

Fraslin JM, Kneip B, Vaulont S, Glaise D, Munnich A, Guguen-Guillouzo C.

EMBO J. 1985 Oct;4(10):2487-91.

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