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Items: 47

1.

Genetic Mutations in a Patient with Chronic Myeloid Leukemia Showing Blast Crisis 10 Years After Presentation.

Sklarz LM, Wittke C, Krohn S, GROßE-Thie C, Junghanss C, Murua Escobar H, Glaeser H.

Anticancer Res. 2018 Jul;38(7):3961-3966. doi: 10.21873/anticanres.12682.

PMID:
29970518
2.

Analysis of amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter organic anion transporting polypeptide 1B1 (OATP1B1).

Gruetz M, Sticht H, Glaeser H, Fromm MF, König J.

Biochim Biophys Acta. 2016 Nov;1858(11):2894-2902. doi: 10.1016/j.bbamem.2016.08.018. Epub 2016 Sep 1.

3.

The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.

Misaka S, Knop J, Singer K, Hoier E, Keiser M, Müller F, Glaeser H, König J, Fromm MF.

Mol Pharm. 2016 Feb 1;13(2):512-9. doi: 10.1021/acs.molpharmaceut.5b00733. Epub 2016 Jan 19.

PMID:
26702643
4.

Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.

Knop J, Misaka S, Singer K, Hoier E, Müller F, Glaeser H, König J, Fromm MF.

PLoS One. 2015 Oct 1;10(10):e0139370. doi: 10.1371/journal.pone.0139370. eCollection 2015.

5.

Interplay between the prostaglandin transporter OATP2A1 and prostaglandin E2-mediated cellular effects.

Bujok K, Glaeser H, Schuh W, Rau TT, Schmidt I, Fromm MF, Mandery K.

Cell Signal. 2015 Mar;27(3):663-72. doi: 10.1016/j.cellsig.2014.11.027. Epub 2014 Nov 26.

PMID:
25433165
6.

Organic anion transporting polypeptides and organic cation transporter 1 contribute to the cellular uptake of the flavonoid quercetin.

Glaeser H, Bujok K, Schmidt I, Fromm MF, Mandery K.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Sep;387(9):883-91. doi: 10.1007/s00210-014-1000-6. Epub 2014 Jun 20.

PMID:
24947867
7.

Response to "the effect of green tea with exceptionally high catechin content on nadolol plasma concentration".

Misaka S, Yatabe J, Müller F, Takano K, Glaeser H, Yatabe MS, Onoue S, Werba JP, Watanabe H, Yamada S, Fromm MF, Kimura J.

Clin Pharmacol Ther. 2014 Jun;95(6):589. doi: 10.1038/clpt.2014.61. Epub 2014 Mar 12. No abstract available.

PMID:
24739447
8.

Green tea ingestion greatly reduces plasma concentrations of nadolol in healthy subjects.

Misaka S, Yatabe J, Müller F, Takano K, Kawabe K, Glaeser H, Yatabe MS, Onoue S, Werba JP, Watanabe H, Yamada S, Fromm MF, Kimura J.

Clin Pharmacol Ther. 2014 Apr;95(4):432-8. doi: 10.1038/clpt.2013.241. Epub 2014 Jan 13.

PMID:
24419562
9.

Inhibition of hepatic uptake transporters by flavonoids.

Mandery K, Balk B, Bujok K, Schmidt I, Fromm MF, Glaeser H.

Eur J Pharm Sci. 2012 May 12;46(1-2):79-85. doi: 10.1016/j.ejps.2012.02.014. Epub 2012 Feb 28.

PMID:
22394605
10.

Interaction of innovative small molecule drugs used for cancer therapy with drug transporters.

Mandery K, Glaeser H, Fromm MF.

Br J Pharmacol. 2012 Jan;165(2):345-62. doi: 10.1111/j.1476-5381.2011.01618.x. Review.

11.

Functional and structural relevance of conserved positively charged lysine residues in organic anion transporting polypeptide 1B3.

Mandery K, Sticht H, Bujok K, Schmidt I, Fahrmayr C, Balk B, Fromm MF, Glaeser H.

Mol Pharmacol. 2011 Sep;80(3):400-6. doi: 10.1124/mol.111.071282. Epub 2011 Jun 3.

PMID:
21642393
12.

Molecular mechanism of renal tubular secretion of the antimalarial drug chloroquine.

Müller F, König J, Glaeser H, Schmidt I, Zolk O, Fromm MF, Maas R.

Antimicrob Agents Chemother. 2011 Jul;55(7):3091-8. doi: 10.1128/AAC.01835-10. Epub 2011 Apr 25.

13.

Role of organic anion-transporting polypeptides for cellular mesalazine (5-aminosalicylic acid) uptake.

König J, Glaeser H, Keiser M, Mandery K, Klotz U, Fromm MF.

Drug Metab Dispos. 2011 Jun;39(6):1097-102. doi: 10.1124/dmd.110.034991. Epub 2011 Mar 23.

PMID:
21430235
14.

Importance of P-glycoprotein for drug-drug interactions.

Glaeser H.

Handb Exp Pharmacol. 2011;(201):285-97. doi: 10.1007/978-3-642-14541-4_7. Review.

PMID:
21103973
15.

Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1.

Mandery K, Bujok K, Schmidt I, Keiser M, Siegmund W, Balk B, König J, Fromm MF, Glaeser H.

Biochem Pharmacol. 2010 Dec 1;80(11):1746-53. doi: 10.1016/j.bcp.2010.08.008. Epub 2010 Aug 24.

PMID:
20797388
16.

Relevance of conserved lysine and arginine residues in transmembrane helices for the transport activity of organic anion transporting polypeptide 1B3.

Glaeser H, Mandery K, Sticht H, Fromm MF, König J.

Br J Pharmacol. 2010 Feb 1;159(3):698-708. doi: 10.1111/j.1476-5381.2009.00568.x. Epub 2010 Jan 22.

17.

The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost.

Kraft ME, Glaeser H, Mandery K, König J, Auge D, Fromm MF, Schlötzer-Schrehardt U, Welge-Lüssen U, Kruse FE, Zolk O.

Invest Ophthalmol Vis Sci. 2010 May;51(5):2504-11. doi: 10.1167/iovs.09-4290. Epub 2009 Dec 17.

PMID:
20019365
18.

Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability.

Ho RH, Leake BF, Kilkenny DM, Meyer Zu Schwabedissen HE, Glaeser H, Kroetz DL, Kim RB.

Pharmacogenet Genomics. 2010 Jan;20(1):45-57. doi: 10.1097/FPC.0b013e3283349eb0.

19.

Influence of cyclooxygenase inhibitors on the function of the prostaglandin transporter organic anion-transporting polypeptide 2A1 expressed in human gastroduodenal mucosa.

Mandery K, Bujok K, Schmidt I, Wex T, Treiber G, Malfertheiner P, Rau TT, Amann KU, Brune K, Fromm MF, Glaeser H.

J Pharmacol Exp Ther. 2010 Feb;332(2):345-51. doi: 10.1124/jpet.109.154518. Epub 2009 Oct 20.

PMID:
19843975
20.

Interaction of beta-blockers with the renal uptake transporter OCT2.

Bachmakov I, Glaeser H, Endress B, Mörl F, König J, Fromm MF.

Diabetes Obes Metab. 2009 Nov;11(11):1080-3. doi: 10.1111/j.1463-1326.2009.01076.x. Epub 2009 Sep 9.

PMID:
19740083
21.

Overexpression of OATP1B3 confers apoptotic resistance in colon cancer.

Lee W, Belkhiri A, Lockhart AC, Merchant N, Glaeser H, Harris EI, Washington MK, Brunt EM, Zaika A, Kim RB, El-Rifai W.

Cancer Res. 2008 Dec 15;68(24):10315-23. doi: 10.1158/0008-5472.CAN-08-1984.

22.

Animal models and intestinal drug transport.

Glaeser H, Fromm MF.

Expert Opin Drug Metab Toxicol. 2008 Apr;4(4):347-61. doi: 10.1517/17425255.4.4.347 . Review.

PMID:
18433341
23.

The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members.

Seithel A, Glaeser H, Fromm MF, König J.

Expert Opin Drug Metab Toxicol. 2008 Jan;4(1):51-64. doi: 10.1517/17425255.4.1.51 . Review.

PMID:
18370858
24.

Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

Bachmakov I, Glaeser H, Fromm MF, König J.

Diabetes. 2008 Jun;57(6):1463-9. doi: 10.2337/db07-1515. Epub 2008 Feb 26.

25.

Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux.

Igel S, Drescher S, Mürdter T, Hofmann U, Heinkele G, Tegude H, Glaeser H, Brenner SS, Somogyi AA, Omari T, Schäfer C, Eichelbaum M, Fromm MF.

Clin Pharmacokinet. 2007;46(9):777-85.

PMID:
17713975
26.

Variability in human hepatic MRP4 expression: influence of cholestasis and genotype.

Gradhand U, Lang T, Schaeffeler E, Glaeser H, Tegude H, Klein K, Fritz P, Jedlitschky G, Kroemer HK, Bachmakov I, Anwald B, Kerb R, Zanger UM, Eichelbaum M, Schwab M, Fromm MF.

Pharmacogenomics J. 2008 Feb;8(1):42-52. Epub 2007 Apr 3.

PMID:
17404579
27.

Induction of intestinal P-glycoprotein by St John's wort reduces the oral bioavailability of talinolol.

Schwarz UI, Hanso H, Oertel R, Miehlke S, Kuhlisch E, Glaeser H, Hitzl M, Dresser GK, Kim RB, Kirch W.

Clin Pharmacol Ther. 2007 May;81(5):669-78. Epub 2007 Mar 28.

PMID:
17392718
28.

Intestinal drug transporter expression and the impact of grapefruit juice in humans.

Glaeser H, Bailey DG, Dresser GK, Gregor JC, Schwarz UI, McGrath JS, Jolicoeur E, Lee W, Leake BF, Tirona RG, Kim RB.

Clin Pharmacol Ther. 2007 Mar;81(3):362-70. Epub 2007 Jan 10.

PMID:
17215845
29.

Inability to upregulate cytochrome P450 4A and 2C causes salt sensitivity in young Sprague-Dawley rats.

Sankaralingam S, Desai KM, Glaeser H, Kim RB, Wilson TW.

Am J Hypertens. 2006 Nov;19(11):1174-80.

PMID:
17070431
30.

Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB.

Gastroenterology. 2006 May;130(6):1793-806. Epub 2006 Mar 6.

PMID:
16697742
31.

Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.

Becquemont L, Glaeser H, Drescher S, Hitzl M, Simon N, Murdter TE, Heinkele G, Hofmann U, Schaefer C, Burk O, Verstuyft C, Eichelbaum M, Fromm MF.

Clin Pharmacol Ther. 2006 May;79(5):449-60. Epub 2006 Apr 11.

PMID:
16678547
32.

Differential in vivo sensitivity to inhibition of P-glycoprotein located in lymphocytes, testes, and the blood-brain barrier.

Choo EF, Kurnik D, Muszkat M, Ohkubo T, Shay SD, Higginbotham JN, Glaeser H, Kim RB, Wood AJ, Wilkinson GR.

J Pharmacol Exp Ther. 2006 Jun;317(3):1012-8. Epub 2006 Mar 14.

PMID:
16537797
33.

Transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1alpha,25-dihydroxyvitamin D3 via the vitamin D receptor.

Chen X, Chen F, Liu S, Glaeser H, Dawson PA, Hofmann AF, Kim RB, Shneider BL, Pang KS.

Mol Pharmacol. 2006 Jun;69(6):1913-23. Epub 2006 Feb 15.

PMID:
16481392
34.

Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes.

Glaeser H, Drescher S, Eichelbaum M, Fromm MF.

Br J Clin Pharmacol. 2005 Feb;59(2):199-206.

35.

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry.

Lee W, Glaeser H, Smith LH, Roberts RL, Moeckel GW, Gervasini G, Leake BF, Kim RB.

J Biol Chem. 2005 Mar 11;280(10):9610-7. Epub 2005 Jan 4.

36.

Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humans.

Glaeser H, Drescher S, Hofmann U, Heinkele G, Somogyi AA, Eichelbaum M, Fromm MF.

Clin Pharmacol Ther. 2004 Sep;76(3):230-8.

PMID:
15371984
37.

Detection of pathogenic micro-organisms--a contribution to discussion.

Glaeser H.

Dtsch Tierarztl Wochenschr. 2004 May;111(5):193-5.

PMID:
15233337
38.

P-glycoprotein-mediated intestinal and biliary digoxin transport in humans.

Drescher S, Glaeser H, Mürdter T, Hitzl M, Eichelbaum M, Fromm MF.

Clin Pharmacol Ther. 2003 Mar;73(3):223-31.

PMID:
12621387
39.

Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4.

Bhardwaj RK, Glaeser H, Becquemont L, Klotz U, Gupta SK, Fromm MF.

J Pharmacol Exp Ther. 2002 Aug;302(2):645-50.

PMID:
12130727
40.

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

Burk O, Tegude H, Koch I, Hustert E, Wolbold R, Glaeser H, Klein K, Fromm MF, Nuessler AK, Neuhaus P, Zanger UM, Eichelbaum M, Wojnowski L.

J Biol Chem. 2002 Jul 5;277(27):24280-8. Epub 2002 Apr 8.

41.

Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters.

Glaeser H, Drescher S, van der Kuip H, Behrens C, Geick A, Burk O, Dent J, Somogyi A, Von Richter O, Griese EU, Eichelbaum M, Fromm MF.

Clin Pharmacol Ther. 2002 Mar;71(3):131-40.

PMID:
11907487
42.

[Adenosine-dependent death of Hydrogenomonas eutropha (Alcaligenes eutrophus) H 16 (author's transl)].

Kaltwasser H, Glaeser H.

Zentralbl Bakteriol Parasitenkd Infektionskr Hyg. 1976;131(8):678-91. German.

PMID:
828363
43.

[NADP- and NAD-specific isocitrate dehydrogenase in Hydrogenomonas eutropha strain H 16].

Glaeser H, Schlegel HG.

Arch Mikrobiol. 1972;86(4):327-37. German. No abstract available.

PMID:
4404355
44.

[Synthesis of enzymes of the tricarboxylic acid cycle in Hydrogenomonas eutropha strain H 16].

Glaeser H, Schlegel HG.

Arch Mikrobiol. 1972;86(4):315-25. German. No abstract available.

PMID:
4404354
45.

[DIPLOZOON NAGIBINAE N. SP., A NEW DIPLOZOON SPECIES (MONOGENOIDEA) OF ABRAMIS BALLERUS (L.)].

GLAESER HJ.

Z Parasitenkd. 1965 Apr 27;25:485-90. German. No abstract available.

PMID:
14305890
46.

[ON DATA ON THE GENUS DACTYLOGYRUS DIESING 1850 (MONOGENOIDEA)].

GLAESER HJ.

Z Parasitenkd. 1965 Apr 27;25:459-84. German. No abstract available.

PMID:
14305889
47.

[TAXONOMY OF THE GENUS DIPLOZOON NORDMANN, 1832].

GLAESER HJ, GLAESER B.

Z Parasitenkd. 1964 Nov 17;25:164-92. German. No abstract available.

PMID:
14332986

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