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Items: 21


MBNL1 overexpression is not sufficient to rescue the phenotypes in a mouse model of RNA toxicity.

Yadava RS, Kim YK, Mandal M, Mahadevan K, Gladman JT, Yu Q, Mahadevan MS.

Hum Mol Genet. 2019 Apr 1. pii: ddz065. doi: 10.1093/hmg/ddz065. [Epub ahead of print]


Reverse Dissection and DiceCT Reveal Otherwise Hidden Data in the Evolution of the Primate Face.

Burrows AM, Omstead KM, Deutsch AR, Gladman JT, Hartstone-Rose A.

J Vis Exp. 2019 Jan 7;(143). doi: 10.3791/58394.


Inferring locomotor behaviours in Miocene New World monkeys using finite element analysis, geometric morphometrics and machine-learning classification techniques applied to talar morphology.

Püschel TA, Marcé-Nogué J, Gladman JT, Bobe R, Sellers WI.

J R Soc Interface. 2018 Sep 26;15(146). pii: 20180520. doi: 10.1098/rsif.2018.0520.


Alzheimer's Disease-Related Dementias Summit 2016: National research priorities.

Corriveau RA, Koroshetz WJ, Gladman JT, Jeon S, Babcock D, Bennett DA, Carmichael ST, Dickinson SL, Dickson DW, Emr M, Fillit H, Greenberg SM, Hutton ML, Knopman DS, Manly JJ, Marder KS, Moy CS, Phelps CH, Scott PA, Seeley WW, Sieber BA, Silverberg NB, Sutherland ML, Taylor A, Torborg CL, Waddy SP, Gubitz AK, Holtzman DM.

Neurology. 2017 Dec 5;89(23):2381-2391. doi: 10.1212/WNL.0000000000004717. Epub 2017 Nov 8. Review.


The evolution of the platyrrhine talus: A comparative analysis of the phenetic affinities of the Miocene platyrrhines with their modern relatives.

Püschel TA, Gladman JT, Bobe R, Sellers WI.

J Hum Evol. 2017 Oct;111:179-201. doi: 10.1016/j.jhevol.2017.07.015. Epub 2017 Aug 29.


The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline.

Corriveau RA, Bosetti F, Emr M, Gladman JT, Koenig JI, Moy CS, Pahigiannis K, Waddy SP, Koroshetz W.

Cell Mol Neurobiol. 2016 Mar;36(2):281-8. doi: 10.1007/s10571-016-0334-7. Epub 2016 Apr 19. Review.


TWEAK Regulates Muscle Functions in a Mouse Model of RNA Toxicity.

Yadava RS, Foff EP, Yu Q, Gladman JT, Zheng TS, Mahadevan MS.

PLoS One. 2016 Feb 22;11(2):e0150192. doi: 10.1371/journal.pone.0150192. eCollection 2016. Erratum in: PLoS One. 2018 Feb 8;13(2):e0192816.


Predicting euarchontan body mass: A comparison of tarsal and dental variables.

Yapuncich GS, Gladman JT, Boyer DM.

Am J Phys Anthropol. 2015 Jul;157(3):472-506. doi: 10.1002/ajpa.22735. Epub 2015 Mar 27.


A new fully automated approach for aligning and comparing shapes.

Boyer DM, Puente J, Gladman JT, Glynn C, Mukherjee S, Yapuncich GS, Daubechies I.

Anat Rec (Hoboken). 2015 Jan;298(1):249-76. doi: 10.1002/ar.23084.


TWEAK/Fn14, a pathway and novel therapeutic target in myotonic dystrophy.

Yadava RS, Foff EP, Yu Q, Gladman JT, Kim YK, Bhatt KS, Thornton CA, Zheng TS, Mahadevan MS.

Hum Mol Genet. 2015 Apr 1;24(7):2035-48. doi: 10.1093/hmg/ddu617. Epub 2014 Dec 11.


NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.

Gladman JT, Yadava RS, Mandal M, Yu Q, Kim YK, Mahadevan MS.

Hum Mol Genet. 2015 Jan 1;24(1):251-64. doi: 10.1093/hmg/ddu443. Epub 2014 Aug 28.


Development of an AP-FRET based analysis for characterizing RNA-protein interactions in myotonic dystrophy (DM1).

Rehman S, Gladman JT, Periasamy A, Sun Y, Mahadevan MS.

PLoS One. 2014 Apr 29;9(4):e95957. doi: 10.1371/journal.pone.0095957. eCollection 2014.


Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).

Gladman JT, Mandal M, Srinivasan V, Mahadevan MS.

PLoS One. 2013 Sep 5;8(9):e72907. doi: 10.1371/journal.pone.0072907. eCollection 2013.


Stress-induced isoforms of MDM2 and MDM4 correlate with high-grade disease and an altered splicing network in pediatric rhabdomyosarcoma.

Jacob AG, O'Brien D, Singh RK, Comiskey DF Jr, Littleton RM, Mohammad F, Gladman JT, Widmann MC, Jeyaraj SC, Bolinger C, Anderson JR, Barkauskas DA, Boris-Lawrie K, Chandler DS.

Neoplasia. 2013 Sep;15(9):1049-63.


Evolution and allometry of calcaneal elongation in living and extinct primates.

Boyer DM, Seiffert ER, Gladman JT, Bloch JI.

PLoS One. 2013 Jul 3;8(7):e67792. doi: 10.1371/journal.pone.0067792. Print 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/77784e61-3a43-4615-85bd-b6b4369568fd.


A calcaneus attributable to the primitive late Eocene anthropoid Proteopithecus sylviae: phenetic affinities and phylogenetic implications.

Gladman JT, Boyer DM, Simons EL, Seiffert ER.

Am J Phys Anthropol. 2013 Jul;151(3):372-97. doi: 10.1002/ajpa.22266.


Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype.

Pierson CR, Dulin-Smith AN, Durban AN, Marshall ML, Marshall JT, Snyder AD, Naiyer N, Gladman JT, Chandler DS, Lawlor MW, Buj-Bello A, Dowling JJ, Beggs AH.

Hum Mol Genet. 2012 Feb 15;21(4):811-25. doi: 10.1093/hmg/ddr512. Epub 2011 Nov 7.


Generation of a tamoxifen inducible SMN mouse for temporal SMN replacement.

Bebee TW, Gladman JT, Chandler DS.

Genesis. 2011 Dec;49(12):927-34. doi: 10.1002/dvg.20764. Epub 2011 Aug 24.


A humanized Smn gene containing the SMN2 nucleotide alteration in exon 7 mimics SMN2 splicing and the SMA disease phenotype.

Gladman JT, Bebee TW, Edwards C, Wang X, Sahenk Z, Rich MM, Chandler DS.

Hum Mol Genet. 2010 Nov 1;19(21):4239-52. doi: 10.1093/hmg/ddq343. Epub 2010 Aug 12.


Splicing of the Survival Motor Neuron genes and implications for treatment of SMA

Bebee TW, Gladman JT, Chandler DS.

Front Biosci (Landmark Ed). 2010 Jun 1;15:1191-1204. Review.


Intron 7 conserved sequence elements regulate the splicing of the SMN genes.

Gladman JT, Chandler DS.

Hum Genet. 2009 Dec;126(6):833-41. doi: 10.1007/s00439-009-0733-7.

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