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Items: 33

1.

CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer.

Hwang JH, Seo JH, Beshiri ML, Wankowicz S, Liu D, Cheung A, Li J, Qiu X, Hong AL, Botta G, Golumb L, Richter C, So J, Sandoval GJ, Giacomelli AO, Ly SH, Han C, Dai C, Pakula H, Sheahan A, Piccioni F, Gjoerup O, Loda M, Sowalsky AG, Ellis L, Long H, Root DE, Kelly K, Van Allen EM, Freedman ML, Choudhury AD, Hahn WC.

Cell Rep. 2019 Nov 19;29(8):2355-2370.e6. doi: 10.1016/j.celrep.2019.10.068.

2.

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition.

Hong AL, Tseng YY, Wala JA, Kim WJ, Kynnap BD, Doshi MB, Kugener G, Sandoval GJ, Howard TP, Li J, Yang X, Tillgren M, Ghandi M, Sayeed A, Deasy R, Ward A, McSteen B, Labella KM, Keskula P, Tracy A, Connor C, Clinton CM, Church AJ, Crompton BD, Janeway KA, Van Hare B, Sandak D, Gjoerup O, Bandopadhayay P, Clemons PA, Schreiber SL, Root DE, Gokhale PC, Chi SN, Mullen EA, Roberts CW, Kadoch C, Beroukhim R, Ligon KL, Boehm JS, Hahn WC.

Elife. 2019 Mar 12;8. pii: e44161. doi: 10.7554/eLife.44161.

3.

An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer.

Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, Ge JY, Root DE, Zhao JJ, Brooks AN, Weinberg RA, Hahn WC.

Elife. 2018 Jul 30;7. pii: e37184. doi: 10.7554/eLife.37184.

4.

Analysis of JC virus DNA replication using a quantitative and high-throughput assay.

Shin J, Phelan PJ, Chhum P, Bashkenova N, Yim S, Parker R, Gagnon D, Gjoerup O, Archambault J, Bullock PA.

Virology. 2014 Nov;468-470:113-125. doi: 10.1016/j.virol.2014.07.042. Epub 2014 Aug 24.

5.

Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase.

Forero A, Giacobbi NS, McCormick KD, Gjoerup OV, Bakkenist CJ, Pipas JM, Sarkar SN.

J Immunol. 2014 Jun 15;192(12):5933-42. doi: 10.4049/jimmunol.1303470. Epub 2014 May 5.

6.

Viral interference with DNA repair by targeting of the single-stranded DNA binding protein RPA.

Banerjee P, DeJesus R, Gjoerup O, Schaffhausen BS.

PLoS Pathog. 2013 Oct;9(10):e1003725. doi: 10.1371/journal.ppat.1003725. Epub 2013 Oct 24.

7.

Replication stress and mitotic dysfunction in cells expressing simian virus 40 large T antigen.

Hu L, Filippakis H, Huang H, Yen TJ, Gjoerup OV.

J Virol. 2013 Dec;87(24):13179-92. doi: 10.1128/JVI.02224-13. Epub 2013 Sep 25.

8.

Formation of covalently modified folding intermediates of simian virus 40 Vp1 in large T antigen-expressing cells.

Watanabe M, Phamduong E, Huang CH, Itoh N, Bernal J, Nakanishi A, Rundell K, Gjoerup O, Kasamatsu H.

J Virol. 2013 May;87(9):5053-64. doi: 10.1128/JVI.00955-12. Epub 2013 Feb 20.

9.

Functional connection between Rad51 and PML in homology-directed repair.

Boichuk S, Hu L, Makielski K, Pandolfi PP, Gjoerup OV.

PLoS One. 2011;6(10):e25814. doi: 10.1371/journal.pone.0025814. Epub 2011 Oct 5.

10.

DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin.

Kucharski TJ, Gamache I, Gjoerup O, Teodoro JG.

J Virol. 2011 Dec;85(23):12638-49. doi: 10.1128/JVI.05009-11. Epub 2011 Sep 21.

11.

Cellular and viral factors regulating Merkel cell polyomavirus replication.

Feng H, Kwun HJ, Liu X, Gjoerup O, Stolz DB, Chang Y, Moore PS.

PLoS One. 2011;6(7):e22468. doi: 10.1371/journal.pone.0022468. Epub 2011 Jul 22.

12.

Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus.

Liu X, Hein J, Richardson SC, Basse PH, Toptan T, Moore PS, Gjoerup OV, Chang Y.

J Biol Chem. 2011 May 13;286(19):17079-90. doi: 10.1074/jbc.M110.192856. Epub 2011 Mar 16.

13.

Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen.

Boichuk S, Hu L, Hein J, Gjoerup OV.

J Virol. 2010 Aug;84(16):8007-20. doi: 10.1128/JVI.00334-10. Epub 2010 Jun 2.

14.

Update on human polyomaviruses and cancer.

Gjoerup O, Chang Y.

Adv Cancer Res. 2010;106:1-51. doi: 10.1016/S0065-230X(10)06001-X. Review.

PMID:
20399955
15.

SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis.

Cheng H, Liu P, Wang ZC, Zou L, Santiago S, Garbitt V, Gjoerup OV, Iglehart JD, Miron A, Richardson AL, Hahn WC, Zhao JJ.

Sci Signal. 2009 Jul 21;2(80):ra35. doi: 10.1126/scisignal.2000369.

16.

Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors.

Shuda M, Arora R, Kwun HJ, Feng H, Sarid R, Fernández-Figueras MT, Tolstov Y, Gjoerup O, Mansukhani MM, Swerdlow SH, Chaudhary PM, Kirkwood JM, Nalesnik MA, Kant JA, Weiss LM, Moore PS, Chang Y.

Int J Cancer. 2009 Sep 15;125(6):1243-9. doi: 10.1002/ijc.24510.

17.

Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding.

Hein J, Boichuk S, Wu J, Cheng Y, Freire R, Jat PS, Roberts TM, Gjoerup OV.

J Virol. 2009 Jan;83(1):117-27. doi: 10.1128/JVI.01515-08. Epub 2008 Oct 15.

18.

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus.

Shuda M, Feng H, Kwun HJ, Rosen ST, Gjoerup O, Moore PS, Chang Y.

Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16272-7. doi: 10.1073/pnas.0806526105. Epub 2008 Sep 23.

19.

Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner.

Andrabi S, Gjoerup OV, Kean JA, Roberts TM, Schaffhausen B.

Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19011-6. Epub 2007 Nov 15.

20.

Bub1: escapades in a cellular world.

Williams GL, Roberts TM, Gjoerup OV.

Cell Cycle. 2007 Jul 15;6(14):1699-704. Epub 2007 May 25. Review.

PMID:
17643075
21.

Preparation of monoclonal antibodies against the spindle checkpoint kinase Bub1.

Lock RL, Szeto TH, Entwistle A, Gjoerup OV, Jat PS.

Hybridoma (Larchmt). 2007 Jun;26(3):140-7.

PMID:
17600495
22.

Surveillance mechanism linking Bub1 loss to the p53 pathway.

Gjoerup OV, Wu J, Chandler-Militello D, Williams GL, Zhao J, Schaffhausen B, Jat PS, Roberts TM.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8334-9. Epub 2007 May 8.

23.

The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation.

Zhao JJ, Cheng H, Jia S, Wang L, Gjoerup OV, Mikami A, Roberts TM.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16296-300. Epub 2006 Oct 23.

24.

Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase.

Kaur R, Liu X, Gjoerup O, Zhang A, Yuan X, Balk SP, Schneider MC, Lu ML.

J Biol Chem. 2005 Feb 4;280(5):3323-30. Epub 2004 Nov 18.

25.

The serine/threonine kinase cyclin G-associated kinase regulates epidermal growth factor receptor signaling.

Zhang L, Gjoerup O, Roberts TM.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10296-301. Epub 2004 Jul 6.

26.

Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1.

Cotsiki M, Lock RL, Cheng Y, Williams GL, Zhao J, Perera D, Freire R, Entwistle A, Golemis EA, Roberts TM, Jat PS, Gjoerup OV.

Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):947-52. Epub 2004 Jan 19.

27.

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase.

Zhao JJ, Gjoerup OV, Subramanian RR, Cheng Y, Chen W, Roberts TM, Hahn WC.

Cancer Cell. 2003 May;3(5):483-95.

28.

Tangled webs: evidence of cross-talk between c-Raf-1 and Akt.

Jun T, Gjoerup O, Roberts TM.

Sci STKE. 1999 Dec 21;1999(13):PE1. Review.

PMID:
11865188
29.

Induction of p53-independent apoptosis by simian virus 40 small t antigen.

Gjoerup O, Zaveri D, Roberts TM.

J Virol. 2001 Oct;75(19):9142-55.

30.

Simian virus 40 large tumor antigen modulates the Raf signaling pathway.

Grammatikakis N, Jaronczyk K, Siganou A, Vultur A, Brownell HL, Benzaquen M, Rausch C, Lapointe R, Gjoerup O, Roberts TM, Raptis L.

J Biol Chem. 2001 Jul 27;276(30):27840-5. Epub 2001 May 29.

31.
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33.

Characterization of an immortalizing N-terminal domain of polyomavirus large T antigen.

Holman PS, Gjoerup OV, Davin T, Schaffhausen BS.

J Virol. 1994 Feb;68(2):668-73.

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