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Items: 50

1.

Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors.

Urbani L, Camilli C, Phylactopoulos DE, Crowley C, Natarajan D, Scottoni F, Maghsoudlou P, McCann CJ, Pellegata AF, Urciuolo A, Deguchi K, Khalaf S, Aruta SF, Signorelli MC, Kiely D, Hannon E, Trevisan M, Wong RR, Baradez MO, Moulding D, Virasami A, Gjinovci A, Loukogeorgakis S, Mantero S, Thapar N, Sebire N, Eaton S, Lowdell M, Cossu G, Bonfanti P, De Coppi P.

Nat Commun. 2018 Oct 16;9(1):4286. doi: 10.1038/s41467-018-06385-w.

2.

Decellularised skeletal muscles allow functional muscle regeneration by promoting host cell migration.

Urciuolo A, Urbani L, Perin S, Maghsoudlou P, Scottoni F, Gjinovci A, Collins-Hooper H, Loukogeorgakis S, Tyraskis A, Torelli S, Germinario E, Fallas MEA, Julia-Vilella C, Eaton S, Blaauw B, Patel K, De Coppi P.

Sci Rep. 2018 May 30;8(1):8398. doi: 10.1038/s41598-018-26371-y.

3.

Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells.

Lorvellec M, Scottoni F, Crowley C, Fiadeiro R, Maghsoudlou P, Pellegata AF, Mazzacuva F, Gjinovci A, Lyne AM, Zulini J, Little D, Mosaku O, Kelly D, De Coppi P, Gissen P.

PLoS One. 2017 Dec 20;12(12):e0189586. doi: 10.1371/journal.pone.0189586. eCollection 2017.

4.

Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis.

Banushi B, Forneris F, Straatman-Iwanowska A, Strange A, Lyne AM, Rogerson C, Burden JJ, Heywood WE, Hanley J, Doykov I, Straatman KR, Smith H, Bem D, Kriston-Vizi J, Ariceta G, Risteli M, Wang C, Ardill RE, Zaniew M, Latka-Grot J, Waddington SN, Howe SJ, Ferraro F, Gjinovci A, Lawrence S, Marsh M, Girolami M, Bozec L, Mills K, Gissen P.

Nat Commun. 2016 Jul 20;7:12111. doi: 10.1038/ncomms12111.

5.

Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development.

Supale S, Thorel F, Merkwirth C, Gjinovci A, Herrera PL, Scorrano L, Meda P, Langer T, Maechler P.

Diabetes. 2013 Oct;62(10):3488-99. doi: 10.2337/db13-0152. Epub 2013 Jul 17.

6.

Specific silencing of the REST target genes in insulin-secreting cells uncovers their participation in beta cell survival.

Martin D, Allagnat F, Gesina E, Caille D, Gjinovci A, Waeber G, Meda P, Haefliger JA.

PLoS One. 2012;7(9):e45844. doi: 10.1371/journal.pone.0045844. Epub 2012 Sep 20.

7.

High-resolution magnetic resonance imaging quantitatively detects individual pancreatic islets.

Lamprianou S, Immonen R, Nabuurs C, Gjinovci A, Vinet L, Montet XC, Gruetter R, Meda P.

Diabetes. 2011 Nov;60(11):2853-60. doi: 10.2337/db11-0726. Epub 2011 Sep 16.

8.

In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.

Hu He KH, Lorenzo PI, Brun T, Jimenez Moreno CM, Aeberhard D, Vallejo Ortega J, Cornu M, Thorel F, Gjinovci A, Thorens B, Herrera PL, Meda P, Wollheim CB, Gauthier BR.

Diabetes. 2011 Jun;60(6):1705-15. doi: 10.2337/db10-1102. Epub 2011 Apr 26.

9.

Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells.

Feldmann N, del Rio RM, Gjinovci A, Tamarit-Rodriguez J, Wollheim CB, Wiederkehr A.

Mol Cell Endocrinol. 2011 May 16;338(1-2):46-57. doi: 10.1016/j.mce.2011.02.019. Epub 2011 Mar 1.

PMID:
21371522
10.

A role for pancreatic beta-cell secretory hyperresponsiveness in catch-up growth hyperinsulinemia: Relevance to thrifty catch-up fat phenotype and risks for type 2 diabetes.

Casimir M, de Andrade PB, Gjinovci A, Montani JP, Maechler P, Dulloo AG.

Nutr Metab (Lond). 2011 Jan 18;8(1):2. doi: 10.1186/1743-7075-8-2.

11.

Comparison of tigecycline and vancomycin for treatment of experimental foreign-body infection due to methicillin-resistant Staphylococcus aureus.

Vaudaux P, Fleury B, Gjinovci A, Huggler E, Tangomo-Bento M, Lew DP.

Antimicrob Agents Chemother. 2009 Jul;53(7):3150-2. doi: 10.1128/AAC.01612-08. Epub 2009 Apr 13.

12.

The Lou/C rat: a model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue.

Veyrat-Durebex C, Montet X, Vinciguerra M, Gjinovci A, Meda P, Foti M, Rohner-Jeanrenaud F.

Am J Physiol Endocrinol Metab. 2009 May;296(5):E1120-32. doi: 10.1152/ajpendo.90592.2008. Epub 2009 Feb 10.

13.

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

Carobbio S, Frigerio F, Rubi B, Vetterli L, Bloksgaard M, Gjinovci A, Pournourmohammadi S, Herrera PL, Reith W, Mandrup S, Maechler P.

J Biol Chem. 2009 Jan 9;284(2):921-9. doi: 10.1074/jbc.M806295200. Epub 2008 Nov 17.

14.

Dietary phytoestrogens activate AMP-activated protein kinase with improvement in lipid and glucose metabolism.

Cederroth CR, Vinciguerra M, Gjinovci A, Kühne F, Klein M, Cederroth M, Caille D, Suter M, Neumann D, James RW, Doerge DR, Wallimann T, Meda P, Foti M, Rohner-Jeanrenaud F, Vassalli JD, Nef S.

Diabetes. 2008 May;57(5):1176-85. doi: 10.2337/db07-0630. Epub 2008 Apr 16.

15.
16.

The Fas pathway is involved in pancreatic beta cell secretory function.

Schumann DM, Maedler K, Franklin I, Konrad D, Størling J, Böni-Schnetzler M, Gjinovci A, Kurrer MO, Gauthier BR, Bosco D, Andres A, Berney T, Greter M, Becher B, Chervonsky AV, Halban PA, Mandrup-Poulsen T, Wollheim CB, Donath MY.

Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2861-6. Epub 2007 Feb 13.

17.

Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

Produit-Zengaffinen N, Davis-Lameloise N, Perreten H, Bécard D, Gjinovci A, Keller PA, Wollheim CB, Herrera P, Muzzin P, Assimacopoulos-Jeannet F.

Diabetologia. 2007 Jan;50(1):84-93. Epub 2006 Nov 28.

PMID:
17131143
18.

Characterization of two distinct liver progenitor cell subpopulations of hematopoietic and hepatic origins.

Corcelle V, Stieger B, Gjinovci A, Wollheim CB, Gauthier BR.

Exp Cell Res. 2006 Sep 10;312(15):2826-36. Epub 2006 May 19.

PMID:
16781709
19.

Intensive therapy with ceftobiprole medocaril of experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.

Vaudaux P, Gjinovci A, Bento M, Li D, Schrenzel J, Lew DP.

Antimicrob Agents Chemother. 2005 Sep;49(9):3789-93.

20.

Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release.

Franklin I, Gromada J, Gjinovci A, Theander S, Wollheim CB.

Diabetes. 2005 Jun;54(6):1808-15.

21.

Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.

Ravier MA, Güldenagel M, Charollais A, Gjinovci A, Caille D, Söhl G, Wollheim CB, Willecke K, Henquin JC, Meda P.

Diabetes. 2005 Jun;54(6):1798-807.

22.

Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors.

Preitner F, Ibberson M, Franklin I, Binnert C, Pende M, Gjinovci A, Hansotia T, Drucker DJ, Wollheim C, Burcelin R, Thorens B.

J Clin Invest. 2004 Feb;113(4):635-45.

23.

Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice.

Schulla V, Renström E, Feil R, Feil S, Franklin I, Gjinovci A, Jing XJ, Laux D, Lundquist I, Magnuson MA, Obermüller S, Olofsson CS, Salehi A, Wendt A, Klugbauer N, Wollheim CB, Rorsman P, Hofmann F.

EMBO J. 2003 Aug 1;22(15):3844-54.

24.

Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells.

Ishihara H, Maechler P, Gjinovci A, Herrera PL, Wollheim CB.

Nat Cell Biol. 2003 Apr;5(4):330-5.

PMID:
12640462
25.

Discrimination between signaling pathways in regulation of specific gene expression by insulin and growth hormone in hepatocytes.

Ribaux P, Gjinovci A, Sadowski HB, Iynedjian PB.

Endocrinology. 2002 Oct;143(10):3766-72.

PMID:
12239086
26.

Implication of glutamate in the kinetics of insulin secretion in rat and mouse perfused pancreas.

Maechler P, Gjinovci A, Wollheim CB.

Diabetes. 2002 Feb;51 Suppl 1:S99-102.

27.

Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice.

Hagenfeldt-Johansson KA, Herrera PL, Wang H, Gjinovci A, Ishihara H, Wollheim CB.

Endocrinology. 2001 Dec;142(12):5311-20.

PMID:
11713231
28.
29.

Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance.

Charollais A, Gjinovci A, Huarte J, Bauquis J, Nadal A, Martín F, Andreu E, Sánchez-Andrés JV, Calabrese A, Bosco D, Soria B, Wollheim CB, Herrera PL, Meda P.

J Clin Invest. 2000 Jul;106(2):235-43.

30.

Short-term insulin-induced glycogen formation in primary hepatocytes as a screening bioassay for insulin action.

Vu L, Pralong WF, Cerini F, Gjinovci A, Stöcklin R, Rose K, Offord RE, Kippen AD.

Anal Biochem. 1998 Aug 15;262(1):17-22.

PMID:
9735143
31.

Liver-specific enhancer of the glucokinase gene.

Iynedjian PB, Marie S, Wang H, Gjinovci A, Nazaryan K.

J Biol Chem. 1996 Nov 15;271(46):29113-20.

32.

Glucokinase and cytosolic phosphoenolpyruvate carboxykinase (GTP) in the human liver. Regulation of gene expression in cultured hepatocytes.

Iynedjian PB, Marie S, Gjinovci A, Genin B, Deng SP, Buhler L, Morel P, Mentha G.

J Clin Invest. 1995 May;95(5):1966-73.

33.

In vivo phosphorylation of the Na,K-ATPase alpha subunit in sciatic nerves of control and diabetic rats: effects of protein kinase modulators.

Borghini I, Geering K, Gjinovci A, Wollheim CB, Pralong WF.

Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6211-5.

34.

Alpha, beta I, beta II, delta, and epsilon protein kinase C isoforms and compound activity in the sciatic nerve of normal and diabetic rats.

Borghini I, Ania-Lahuerta A, Regazzi R, Ferrari G, Gjinovci A, Wollheim CB, Pralong WF.

J Neurochem. 1994 Feb;62(2):686-96.

PMID:
8294931
35.

Glucagon-like peptide-I-(7-37) suppresses hyperglycemia in rats.

Hendrick GK, Gjinovci A, Baxter LA, Mojsov S, Wollheim CB, Habener JF, Weir GC.

Metabolism. 1993 Jan;42(1):1-6.

PMID:
8446036
36.
37.

Unimpaired effect of insulin on glucokinase gene expression in hepatocytes challenged with amylin.

Nouspikel T, Gjinovci A, Li S, Iynedjian PB.

FEBS Lett. 1992 Apr 13;301(1):115-8.

38.

Inverse relationship between glucose metabolism and glucose-induced insulin secretion in rat insulinoma cells.

Trautmann ME, Blondel B, Gjinovci A, Wollheim CB.

Horm Res. 1990;34(2):75-82.

PMID:
2097293
39.

Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats.

Iynedjian PB, Gjinovci A, Renold AE.

J Biol Chem. 1988 Jan 15;263(2):740-4.

40.

Direct stimulation of enzyme secretion from rat exocrine pancreas by neurotensin and its naturally occurring fragments.

Trimble ER, Shaw C, Bruzzone R, Gjinovci A, Buchanan KD.

Gastroenterology. 1987 Mar;92(3):699-703.

PMID:
2434384
41.

Regulation of pancreatic exocrine function: a role for cell-to-cell communication?

Bruzzone R, Trimble ER, Gjinovci A, Traub O, Willecke K, Meda P.

Pancreas. 1987;2(3):262-71.

PMID:
3628228
42.

Differences in pancreatic enzyme release from ventral and dorsal areas of the rat pancreas.

Bruzzone R, Trimble ER, Gjinovci A, Renold AE.

Am J Physiol. 1986 Jul;251(1 Pt 1):G56-63.

PMID:
2425638
43.

Activity of the insulo-acinar axis in the isolated perfused rat pancreas.

Trimble ER, Bruzzone R, Gjinovci A, Renold AE.

Endocrinology. 1985 Sep;117(3):1246-52.

PMID:
2410239
44.

A new, rapid, method for preparation of dispersed pancreatic acini.

Bruzzone R, Halban PA, Gjinovci A, Trimble ER.

Biochem J. 1985 Mar 1;226(2):621-4.

45.

Glucose-insulin interactions on exocrine secretion from the perfused rat pancreas.

Bruzzone R, Trimble ER, Gjinovci A, Renold AE.

Gastroenterology. 1984 Dec;87(6):1305-12.

PMID:
6208076
46.

Increased insulin responsiveness in vivo and in vitro consequent to induced hyperinsulinemia in the rat.

Trimble ER, Weir GC, Gjinovci A, Assimacopoulos-Jeannet F, Benzi R, Renold AE.

Diabetes. 1984 May;33(5):444-9.

PMID:
6144606
47.

Changes in content and secretion of pancreatic enzymes in the obese Zucker rat.

Bruzzone R, Trimble ER, Gjinovci A, Renold AE.

Biochem J. 1984 Apr 1;219(1):333-6.

48.

Stimulation of insulin release by glucose in a transplantable rat islet cell tumor.

Masiello P, Wollheim CB, Janjic D, Gjinovci A, Blondel B, Praz GA, Renold AE.

Endocrinology. 1982 Dec;111(6):2091-6.

PMID:
6183110
49.

Biologic activity and pharmacokinetics of biosynthetic human insulin in the rat.

Halban PA, Berger M, Gjinovci A, Renold AE.

Diabetes Care. 1981 Mar-Apr;4(2):238-43.

PMID:
7011735
50.

Increased clearance and degradation of [3H]insulin in streptozotocin diabetic rats.

Philippe J, Halban PA, Gjinovci A, Duckworth WC, Estreicher J, Renold AE.

J Clin Invest. 1981 Mar;67(3):673-80.

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