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Items: 35


Kinetics of immune cell reconstitution predict survival in allogeneic bone marrow and G-CSF-mobilized stem cell transplantation.

Waller EK, Logan BR, Fei M, Lee SJ, Confer D, Howard A, Chandrakasan S, Anasetti C, Fernando SM, Giver CR.

Blood Adv. 2019 Aug 13;3(15):2250-2263. doi: 10.1182/bloodadvances.2018029892.


Indoles derived from intestinal microbiota act via type I interferon signaling to limit graft-versus-host disease.

Swimm A, Giver CR, DeFilipp Z, Rangaraju S, Sharma A, Ulezko Antonova A, Sonowal R, Capaldo C, Powell D, Qayed M, Kalman D, Waller EK.

Blood. 2018 Dec 6;132(23):2506-2519. doi: 10.1182/blood-2018-03-838193. Epub 2018 Sep 26.


A Prospective Trial of Extracorporeal Photopheresis for Chronic Graft-versus-Host Disease Reveals Significant Disease Response and No Association with Frequency of Regulatory T Cells.

Gandelman JS, Song DJ, Chen H, Engelhardt BG, Chen YB, Clark WB, Giver CR, Waller EK, Jung DK, Jagasia M.

Biol Blood Marrow Transplant. 2018 Dec;24(12):2373-2380. doi: 10.1016/j.bbmt.2018.06.035. Epub 2018 Jul 5.


Peritransplantation Red Blood Cell Transfusion Is Associated with Increased Risk of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.

Hosoba S, Waller EK, Shenvi N, Graiser M, Easley KA, Al-Kadhimi Z, Andoh A, Antun AG, Barclay S, Josephson CD, Koff JL, Khoury HJ, Langston AA, Zimring JC, Roback JD, Giver CR.

Biol Blood Marrow Transplant. 2018 May;24(5):973-982. doi: 10.1016/j.bbmt.2018.01.003. Epub 2018 Jan 4.


Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells.

Furlan SN, Watkins B, Tkachev V, Cooley S, Panoskaltsis-Mortari A, Betz K, Brown M, Hunt DJ, Schell JB, Zeleski K, Yu A, Giver CR, Waller EK, Miller JS, Blazar BR, Kean LS.

Blood. 2016 Nov 24;128(21):2568-2579. Epub 2016 Oct 6.


Modulation of Immune Checkpoints and Graft-versus-Leukemia in Allogeneic Transplants by Antagonizing Vasoactive Intestinal Peptide Signaling.

Li JM, Petersen CT, Li JX, Panjwani R, Chandra DJ, Giver CR, Blazar BR, Waller EK.

Cancer Res. 2016 Dec 1;76(23):6802-6815. Epub 2016 Sep 26.


Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.

Furlan SN, Watkins B, Tkachev V, Flynn R, Cooley S, Ramakrishnan S, Singh K, Giver C, Hamby K, Stempora L, Garrett A, Chen J, Betz KM, Ziegler CG, Tharp GK, Bosinger SE, Promislow DE, Miller JS, Waller EK, Blazar BR, Kean LS.

Sci Transl Med. 2015 Nov 25;7(315):315ra191. doi: 10.1126/scitranslmed.aad3231.


Low doses of imatinib induce myelopoiesis and enhance host anti-microbial immunity.

Napier RJ, Norris BA, Swimm A, Giver CR, Harris WA, Laval J, Napier BA, Patel G, Crump R, Peng Z, Bornmann W, Pulendran B, Buller RM, Weiss DS, Tirouvanziam R, Waller EK, Kalman D.

PLoS Pathog. 2015 Mar 30;11(3):e1004770. doi: 10.1371/journal.ppat.1004770. eCollection 2015 Mar.


CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis.

Kaliyaperumal S, Watkins B, Sharma P, Furlan S, Ramakrishnan S, Giver C, Garcia A, Courtney C, Knight H, Strobert E, Elder E, Crenshaw T, Blazar BR, Waller EK, Westmoreland S, Kean LS.

Blood. 2014 Mar 20;123(12):1967-9. doi: 10.1182/blood-2014-01-547612. No abstract available.


Host bone marrow-derived IL-12 enhances donor T cell engraftment in a mouse model of bone marrow transplantation.

Darlak KA, Wang Y, Li JM, Harris WA, Giver CR, Huang C, Waller EK.

J Hematol Oncol. 2014 Feb 28;7:16. doi: 10.1186/1756-8722-7-16.


Properties of immature myeloid progenitors with nitric-oxide-dependent immunosuppressive activity isolated from bone marrow of tumor-free mice.

Forghani P, Harris W, Giver CR, Mirshafiey A, Galipeau J, Waller EK.

PLoS One. 2013 Jul 2;8(7):e64837. doi: 10.1371/journal.pone.0064837. Print 2013.


IFN-γ and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity.

Lu Y, Giver CR, Sharma A, Li JM, Darlak KA, Owens LM, Roback JD, Galipeau J, Waller EK.

Blood. 2012 Jan 26;119(4):1075-85. doi: 10.1182/blood-2010-12-322891. Epub 2011 Nov 30.


Recovery and rebound of platelet counts in mice after thrombocytopenia induced by combination bortezomib + romidepsin.

Giver CR, Jaye DL, Waller EK, Lonial S.

Exp Hematol. 2012 Feb;40(2):95-6. doi: 10.1016/j.exphem.2011.11.002. Epub 2011 Nov 18. No abstract available.


Absence of vasoactive intestinal peptide expression in hematopoietic cells enhances Th1 polarization and antiviral immunity in mice.

Li JM, Southerland L, Hossain MS, Giver CR, Wang Y, Darlak K, Harris W, Waschek J, Waller EK.

J Immunol. 2011 Jul 15;187(2):1057-65. doi: 10.4049/jimmunol.1100686. Epub 2011 Jun 15.


Rapid recovery from panobinostat (LBH589)-induced thrombocytopenia in mice involves a rebound effect of bone marrow megakaryocytes.

Giver CR, Jaye DL, Waller EK, Kaufman JL, Lonial S.

Leukemia. 2011 Feb;25(2):362-5. doi: 10.1038/leu.2010.262. Epub 2010 Nov 26. No abstract available.


Receiver operating characteristic curve analysis of circulating blood dendritic cell precursors and T cells predicts response to extracorporeal photopheresis in patients with chronic graft-versus-host disease.

Akhtari M, Giver CR, Ali Z, Flowers CR, Gleason CL, Hillyer CD, Kaufman J, Khoury HJ, Langston AA, Lechowicz MJ, Lonial S, Renfroe HM, Roback JD, Tighiouart M, Vaughn L, Waller EK.

Transfusion. 2010 Nov;50(11):2424-31. doi: 10.1111/j.1537-2995.2010.02712.x.


Separating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.

Li JM, Giver CR, Lu Y, Hossain MS, Akhtari M, Waller EK.

Immunotherapy. 2009 Jul;1(4):599-621. Review.


Activation, immune polarization, and graft-versus-leukemia activity of donor T cells are regulated by specific subsets of donor bone marrow antigen-presenting cells in allogeneic hemopoietic stem cell transplantation.

Li JM, Southerland LT, Lu Y, Darlak KA, Giver CR, McMillin DW, Harris WA, Jaye DL, Waller EK.

J Immunol. 2009 Dec 15;183(12):7799-809. doi: 10.4049/jimmunol.0900155.


Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma.

Lonial S, Waller EK, Richardson PG, Jagannath S, Orlowski RZ, Giver CR, Jaye DL, Francis D, Giusti S, Torre C, Barlogie B, Berenson JR, Singhal S, Schenkein DP, Esseltine DL, Anderson J, Xiao H, Heffner LT, Anderson KC; SUMMIT/CREST Investigators.

Blood. 2005 Dec 1;106(12):3777-84. Epub 2005 Aug 11.


Facilitating T-cell immune reconstitution after haploidentical transplantation in adults.

Waller EK, Giver CR, Rosenthal H, Somani J, Langston AA, Lonial S, Roback JD, Li JM, Hossain MS, Redei I.

Blood Cells Mol Dis. 2004 Nov-Dec;33(3):233-7.


Reconstructing immunity after allogeneic transplantation.

Giver CR, Li JM, Hossain MS, Lonial S, Waller EK.

Immunol Res. 2004;29(1-3):269-82. Review.


Ex vivo fludarabine exposure inhibits graft-versus-host activity of allogeneic T cells while preserving graft-versus-leukemia effects.

Giver CR, Montes RO, Mittelstaedt S, Li JM, Jaye DL, Lonial S, Boyer MW, Waller EK.

Biol Blood Marrow Transplant. 2003 Oct;9(10):616-32.


Genomic instability in human lymphoid cells exposed to 1 GeV/amu Fe ions.

Grosovsky A, Bethel H, Parks K, Ritter L, Giver C, Gauny S, Wiese C, Kronenberg A.

Phys Med. 2001;17 Suppl 1:238-40.


Dermal benzene and trichloroethylene induce aneuploidy in immature hematopoietic subpopulations in vivo.

Giver CR, Wong R, Moore DH 2nd, Pallavicini MG.

Environ Mol Mutagen. 2001;37(3):185-94.


Persistence of aneuploid immature/primitive hemopoietic sub-populations in mice 8 months after benzene exposure in vivo.

Giver CR, Wong R, Moore DH 2nd, Pallavicini MG.

Mutat Res. 2001 Apr 5;491(1-2):127-38.


Radiation-induced translocations in mice: persistence, chromosome specificity, and influence of genetic background.

Giver CR, Moore DH 2nd, Pallavicini MG.

Radiat Res. 2000 Sep;154(3):283-92.


Radiation specific patterns of loss of heterozygosity on chromosome 17q.

Giver CR, Grosovsky AJ.

Mutat Res. 2000 May 30;450(1-2):201-9.


Clonal analysis of delayed karyotypic abnormalities and gene mutations in radiation-induced genetic instability.

Grosovsky AJ, Parks KK, Giver CR, Nelson SL.

Mol Cell Biol. 1996 Nov;16(11):6252-62.


Mutational spectrum of X-ray induced TK- human cell mutants.

Giver CR, Nelson SL Jr, Cha MY, Pongsaensook P, Grosovsky AJ.

Carcinogenesis. 1995 Feb;16(2):267-75.


Extensive loss of heterozygosity accounts for differential mutation rate on chromosome 17q in human lymphoblasts.

Dobo KL, Giver CR, Eastmond DA, Rumbos HS, Grosovsky AJ.

Mutagenesis. 1995 Jan;10(1):53-8.


Spectrum of X-ray-induced mutations in the human hprt gene.

Nelson SL, Giver CR, Grosovsky AJ.

Carcinogenesis. 1994 Mar;15(3):495-502.


DNA-sequence specificity of mutations at the human thymidine kinase locus.

Grosovsky AJ, Walter BN, Giver CR.

Mutat Res. 1993 Oct;289(2):231-43.


Spectrum of spontaneous HPRT- mutations in TK6 human lymphoblasts.

Giver CR, Nelson SL, Grosovsky AJ.

Environ Mol Mutagen. 1993;22(3):138-46.


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