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Items: 27

1.

Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5).

Pearson AJ, Fullwood P, Toro Tapia G, Prise I, Smith MP, Xu Q, Jordan A, Giurisato E, Whitmarsh AJ, Francavilla C, Tournier C.

Int J Mol Sci. 2020 Jan 31;21(3). pii: E929. doi: 10.3390/ijms21030929.

2.

Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome.

Gatta LB, Melocchi L, Bugatti M, Missale F, Lonardi S, Zanetti B, Cristinelli L, Belotti S, Simeone C, Ronca R, Grillo E, Licini S, Bresciani D, Tardanico R, Chan SR, Giurisato E, Calza S, Vermi W.

Cancers (Basel). 2019 Aug 21;11(9). pii: E1219. doi: 10.3390/cancers11091219.

3.

Defective spermatogenesis and testosterone levels in kinase suppressor of Ras1 (KSR1)-deficient mice.

Moretti E, Collodel G, Belmonte G, Noto D, Giurisato E.

Reprod Fertil Dev. 2019 Apr 15. doi: 10.1071/RD18386. [Epub ahead of print]

PMID:
30981290
4.

Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition.

Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, Finegan KG, Wang W, Wang J, Gray NS, Vermi W, Xia Z, Tournier C.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2801-E2810. doi: 10.1073/pnas.1707929115. Epub 2018 Mar 5.

5.

Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5.

Gilbert AS, Seoane PI, Sephton-Clark P, Bojarczuk A, Hotham R, Giurisato E, Sarhan AR, Hillen A, Velde GV, Gray NS, Alessi DR, Cunningham DL, Tournier C, Johnston SA, May RC.

Sci Adv. 2017 Aug 16;3(8):e1700898. doi: 10.1126/sciadv.1700898. eCollection 2017 Aug.

6.

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.

Young HL, Rowling EJ, Bugatti M, Giurisato E, Luheshi N, Arozarena I, Acosta JC, Kamarashev J, Frederick DT, Cooper ZA, Reuben A, Gil J, Flaherty KT, Wargo JA, Vermi W, Smith MP, Wellbrock C, Hurlstone A.

J Exp Med. 2017 Jun 5;214(6):1691-1710. doi: 10.1084/jem.20160855. Epub 2017 Apr 27.

7.

Can tumor cells proliferate without ERK5?

Giurisato E, Tournier C.

Cell Cycle. 2016;15(5):619-20. doi: 10.1080/15384101.2016.1143272. No abstract available.

8.

Correction: Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.

Gambini L, Rizzi L, Pedretti A, Taglialatela-Scafati O, Carucci M, Pancotti A, Galli C, Read M, Giurisato E, Romeo S, Russo I.

PLoS One. 2016 Jan 4;11(1):e0146627. doi: 10.1371/journal.pone.0146627. eCollection 2016. No abstract available.

9.

Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.

Gambini L, Rizzi L, Pedretti A, Taglialatela-Scafati O, Carucci M, Pancotti A, Galli C, Read M, Giurisato E, Romeo S, Russo I.

PLoS One. 2015 Nov 13;10(11):e0142509. doi: 10.1371/journal.pone.0142509. eCollection 2015. Erratum in: PLoS One. 2016;11(1):e0146627.

10.

Ultrastructural study of spermatogenesis in KSR2 deficient mice.

Moretti E, Collodel G, Mazzi L, Russo I, Giurisato E.

Transgenic Res. 2015 Aug;24(4):741-51. doi: 10.1007/s11248-015-9886-4. Epub 2015 Jun 9.

PMID:
26055731
11.

The KSR2-calcineurin complex regulates STIM1-ORAI1 dynamics and store-operated calcium entry (SOCE).

Giurisato E, Gamberucci A, Ulivieri C, Marruganti S, Rossi E, Giacomello E, Randazzo D, Sorrentino V.

Mol Biol Cell. 2014 Jun;25(11):1769-81. doi: 10.1091/mbc.E13-05-0292. Epub 2014 Mar 26.

12.

Ligand-dependent activation of EGFR in follicular dendritic cells sarcoma is sustained by local production of cognate ligands.

Vermi W, Giurisato E, Lonardi S, Balzarini P, Rossi E, Medicina D, Bosisio D, Sozzani S, Pellegrini W, Doglioni C, Marchetti A, Rossi G, Pileri S, Facchetti F.

Clin Cancer Res. 2013 Sep 15;19(18):5027-38. doi: 10.1158/1078-0432.CCR-13-1275. Epub 2013 Jul 25.

13.

KSR1 modulates the sensitivity of mitogen-activated protein kinase pathway activation in T cells without altering fundamental system outputs.

Lin J, Harding A, Giurisato E, Shaw AS.

Mol Cell Biol. 2009 Apr;29(8):2082-91. doi: 10.1128/MCB.01634-08. Epub 2009 Feb 2.

14.

The mitogen-activated protein kinase scaffold KSR1 is required for recruitment of extracellular signal-regulated kinase to the immunological synapse.

Giurisato E, Lin J, Harding A, Cerutti E, Cella M, Lewis RE, Colonna M, Shaw AS.

Mol Cell Biol. 2009 Mar;29(6):1554-64. doi: 10.1128/MCB.01421-08. Epub 2009 Jan 12.

15.

The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality.

Cemerski S, Das J, Giurisato E, Markiewicz MA, Allen PM, Chakraborty AK, Shaw AS.

Immunity. 2008 Sep 19;29(3):414-22. doi: 10.1016/j.immuni.2008.06.014. Epub 2008 Aug 28.

16.

Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse.

Giurisato E, Cella M, Takai T, Kurosaki T, Feng Y, Longmore GD, Colonna M, Shaw AS.

Mol Cell Biol. 2007 Dec;27(24):8583-99. Epub 2007 Oct 8.

17.

The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse.

Cemerski S, Das J, Locasale J, Arnold P, Giurisato E, Markiewicz MA, Fremont D, Allen PM, Chakraborty AK, Shaw AS.

Immunity. 2007 Mar;26(3):345-55. Epub 2007 Mar 8.

18.
19.

Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics.

Graham DB, Cella M, Giurisato E, Fujikawa K, Miletic AV, Kloeppel T, Brim K, Takai T, Shaw AS, Colonna M, Swat W.

J Immunol. 2006 Aug 15;177(4):2349-55.

20.

Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155).

Fuchs A, Cella M, Giurisato E, Shaw AS, Colonna M.

J Immunol. 2004 Apr 1;172(7):3994-8.

21.

Physiological T cell activation starts and propagates in lipid rafts.

Pizzo P, Giurisato E, Bigsten A, Tassi M, Tavano R, Shaw A, Viola A.

Immunol Lett. 2004 Jan 30;91(1):3-9.

PMID:
14757363
22.

Macrophage-secreted myogenic factors: a promising tool for greatly enhancing the proliferative capacity of myoblasts in vitro and in vivo.

Cantini M, Giurisato E, Radu C, Tiozzo S, Pampinella F, Senigaglia D, Zaniolo G, Mazzoleni F, Vitiello L.

Neurol Sci. 2002 Oct;23(4):189-94.

PMID:
12536288
23.

T cell receptor can be recruited to a subset of plasma membrane rafts, independently of cell signaling and attendantly to raft clustering.

Giurisato E, McIntosh DP, Tassi M, Gamberucci A, Benedetti A.

J Biol Chem. 2003 Feb 28;278(9):6771-8. Epub 2002 Dec 22.

24.

Lipid rafts and T cell receptor signaling: a critical re-evaluation.

Pizzo P, Giurisato E, Tassi M, Benedetti A, Pozzan T, Viola A.

Eur J Immunol. 2002 Nov;32(11):3082-91.

25.

Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products.

Gamberucci A, Giurisato E, Pizzo P, Tassi M, Giunti R, McIntosh DP, Benedetti A.

Biochem J. 2002 May 15;364(Pt 1):245-54. Erratum in: Biochem J 2002 Sep 15;366(Pt 3):999.

26.

Inhibition of fasL sustains phagocytic cells and delays myogenesis in regenerating muscle fibers.

Sandri M, Sandri C, Brun B, Giurisato E, Cantini M, Rossini K, Destro C, Arslan P, Carraro U.

J Leukoc Biol. 2001 Mar;69(3):482-9.

PMID:
11261797
27.

Dystrophin deficient myotubes undergo apoptosis in mouse primary muscle cell culture after DNA damage.

Sandri M, Massimino ML, Cantini M, Giurisato E, Sandri C, Arslan P, Carraro U.

Neurosci Lett. 1998 Aug 14;252(2):123-6.

PMID:
9756337

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