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Items: 39


Structural characterization of a protein adsorbed on aluminum hydroxide adjuvant in vaccine formulation.

Cerofolini L, Giuntini S, Ravera E, Luchinat C, Berti F, Fragai M.

NPJ Vaccines. 2019 May 28;4:20. doi: 10.1038/s41541-019-0115-7. eCollection 2019.


Real-Time Insights into Biological Events: In-Cell Processes and Protein-Ligand Interactions.

Cerofolini L, Giuntini S, Barbieri L, Pennestri M, Codina A, Fragai M, Banci L, Luchinat E, Ravera E.

Biophys J. 2019 Jan 22;116(2):239-247. doi: 10.1016/j.bpj.2018.11.3132. Epub 2018 Dec 6.


Metal centers in biomolecular solid-state NMR.

Malanho Silva J, Cerofolini L, Giuntini S, Calderone V, Geraldes CFGC, Macedo AL, Parigi G, Fragai M, Ravera E, Luchinat C.

J Struct Biol. 2019 Apr 1;206(1):99-109. doi: 10.1016/j.jsb.2018.11.013. Epub 2018 Nov 28.


Non-crystallographic symmetry in proteins: Jahn-Teller-like and Butterfly-like effects?

Silva JM, Giuntini S, Cerofolini L, Geraldes CFGC, Macedo AL, Ravera E, Fragai M, Luchinat C, Calderone V.

J Biol Inorg Chem. 2019 Feb;24(1):91-101. doi: 10.1007/s00775-018-1630-0. Epub 2018 Nov 23.


Characterization of PEGylated Asparaginase: New Opportunities from NMR Analysis of Large PEGylated Therapeutics.

Cerofolini L, Giuntini S, Carlon A, Ravera E, Calderone V, Fragai M, Parigi G, Luchinat C.

Chemistry. 2019 Feb 6;25(8):1984-1991. doi: 10.1002/chem.201804488. Epub 2019 Jan 9.


Correction for Giuntini et al., "Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis against Enterotoxigenic Escherichia coli Infection".

Giuntini S, Stoppato M, Sedic M, Ejemel M, Pondish JR, Wisheart D, Schiller ZA, Thomas WD Jr, Barry EM, Cavacini LA, Klempner MS, Wang Y.

Infect Immun. 2018 Nov 20;86(12). pii: e00713-18. doi: 10.1128/IAI.00713-18. Print 2018 Dec. No abstract available.


A small heterobifunctional ligand provides stable and water dispersible core-shell CdSe/ZnS quantum dots (QDs).

Salerno G, Scarano S, Mamusa M, Consumi M, Giuntini S, Macagnano A, Nativi S, Fragai M, Minunni M, Berti D, Magnani A, Nativi C, Richichi B.

Nanoscale. 2018 Nov 1;10(42):19720-19732. doi: 10.1039/c8nr05566a.


Protein Glycosylation through Sulfur Fluoride Exchange (SuFEx) Chemistry: The Key Role of a Fluorosulfate Thiolactoside.

Marra A, Dong J, Ma T, Giuntini S, Crescenzo E, Cerofolini L, Martinucci M, Luchinat C, Fragai M, Nativi C, Dondoni A.

Chemistry. 2018 Dec 17;24(71):18981-18987. doi: 10.1002/chem.201803912. Epub 2018 Nov 26.


Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis against Enterotoxigenic Escherichia coli Infection.

Giuntini S, Stoppato M, Sedic M, Ejemel M, Pondish JR, Wisheart D, Schiller ZA, Thomas WD Jr, Barry EM, Cavacini LA, Klempner MS, Wang Y.

Infect Immun. 2018 Jul 23;86(8). pii: e00355-18. doi: 10.1128/IAI.00355-18. Print 2018 Aug. Erratum in: Infect Immun. 2018 Nov 20;86(12):.


Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.

Merlino F, Daniele S, La Pietra V, Di Maro S, Di Leva FS, Brancaccio D, Tomassi S, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Reichart F, Cavallini C, Costa B, Piccarducci R, Taliani S, Da Settimo F, Martini C, Kessler H, Novellino E, Marinelli L.

J Med Chem. 2018 Jun 14;61(11):4791-4809. doi: 10.1021/acs.jmedchem.8b00004. Epub 2018 Jun 4.


Engineering l-asparaginase for spontaneous formation of calcium phosphate bioinspired microreactors.

Louka A, Matlahov I, Giuntini S, Cerofolini L, Cavallo A, Pillozzi S, Ravera E, Fragai M, Arcangeli A, Ramamoorthy A, Goobes G, Luchinat C.

Phys Chem Chem Phys. 2018 May 9;20(18):12719-12726. doi: 10.1039/c8cp00419f.


Atomic structural details of a protein grafted onto gold nanoparticles.

Giuntini S, Cerofolini L, Ravera E, Fragai M, Luchinat C.

Sci Rep. 2017 Dec 20;7(1):17934. doi: 10.1038/s41598-017-18109-z.


Long-range paramagnetic NMR data can provide a closer look on metal coordination in metalloproteins.

Cerofolini L, Staderini T, Giuntini S, Ravera E, Fragai M, Parigi G, Pierattelli R, Luchinat C.

J Biol Inorg Chem. 2018 Jan;23(1):71-80. doi: 10.1007/s00775-017-1511-y. Epub 2017 Dec 7.


Characterization of the Conjugation Pattern in Large Polysaccharide-Protein Conjugates by NMR Spectroscopy.

Giuntini S, Balducci E, Cerofolini L, Ravera E, Fragai M, Berti F, Luchinat C.

Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14997-15001. doi: 10.1002/anie.201709274. Epub 2017 Oct 19.


Regulation of HuR structure and function by dihydrotanshinone-I.

Lal P, Cerofolini L, D'Agostino VG, Zucal C, Fuccio C, Bonomo I, Dassi E, Giuntini S, Di Maio D, Vishwakarma V, Preet R, Williams SN, Fairlamb MS, Munk R, Lehrmann E, Abdelmohsen K, Elezgarai SR, Luchinat C, Novellino E, Quattrone A, Biasini E, Manzoni L, Gorospe M, Dixon DA, Seneci P, Marinelli L, Fragai M, Provenzani A.

Nucleic Acids Res. 2017 Sep 19;45(16):9514-9527. doi: 10.1093/nar/gkx623.


Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity.

Giustiniano M, Daniele S, Pelliccia S, La Pietra V, Pietrobono D, Brancaccio D, Cosconati S, Messere A, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Taliani S, La Regina G, Da Settimo F, Silvestri R, Martini C, Novellino E, Marinelli L.

J Med Chem. 2017 Oct 12;60(19):8115-8130. doi: 10.1021/acs.jmedchem.7b00912. Epub 2017 Sep 30.


High-Resolution Solid-State NMR Characterization of Ligand Binding to a Protein Immobilized in a Silica Matrix.

Cerofolini L, Giuntini S, Louka A, Ravera E, Fragai M, Luchinat C.

J Phys Chem B. 2017 Aug 31;121(34):8094-8101. doi: 10.1021/acs.jpcb.7b05679. Epub 2017 Aug 16.


The role of anti-NHba antibody in bactericidal activity elicited by the meningococcal serogroup B vaccine, MenB-4C.

Partridge E, Lujan E, Giuntini S, Vu DM, Granoff DM.

Vaccine. 2017 Jul 24;35(33):4236-4244. doi: 10.1016/j.vaccine.2017.06.020. Epub 2017 Jun 23.


Breadth and Duration of Meningococcal Serum Bactericidal Activity in Health Care Workers and Microbiologists Immunized with the MenB-FHbp Vaccine.

Lujan E, Partridge E, Giuntini S, Ram S, Granoff DM.

Clin Vaccine Immunol. 2017 Aug 4;24(8). pii: e00121-17. doi: 10.1128/CVI.00121-17. Print 2017 Aug.


Serum Bactericidal Antibody Responses of Adults Immunized with the MenB-4C Vaccine against Genetically Diverse Serogroup B Meningococci.

Giuntini S, Lujan E, Gibani MM, Dold C, Rollier CS, Pollard AJ, Granoff DM.

Clin Vaccine Immunol. 2017 Jan 5;24(1). pii: e00430-16. doi: 10.1128/CVI.00430-16. Print 2017 Jan.


Enhanced protective antibody to a mutant meningococcal factor H-binding protein with low-factor H binding.

Granoff DM, Giuntini S, Gowans FA, Lujan E, Sharkey K, Beernink PT.

JCI Insight. 2016 Sep 8;1(14):e88907. doi: 10.1172/jci.insight.88907.


Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity.

Giuntini S, Granoff DM, Beernink PT, Ihle O, Bratlie D, Michaelsen TE.

Clin Vaccine Immunol. 2016 Aug 5;23(8):698-706. doi: 10.1128/CVI.00193-16. Print 2016 Aug.


Solid-State NMR of PEGylated Proteins.

Ravera E, Ciambellotti S, Cerofolini L, Martelli T, Kozyreva T, Bernacchioni C, Giuntini S, Fragai M, Turano P, Luchinat C.

Angew Chem Int Ed Engl. 2016 Feb 12;55(7):2446-9. doi: 10.1002/anie.201510148. Epub 2016 Jan 12.


Effect of complement Factor H on anti-FHbp serum bactericidal antibody responses of infant rhesus macaques boosted with a licensed meningococcal serogroup B vaccine.

Giuntini S, Beernink PT, Granoff DM.

Vaccine. 2015 Dec 16;33(51):7168-7175. doi: 10.1016/j.vaccine.2015.10.135. Epub 2015 Nov 10.


Susceptibility of Meningococcal Strains Responsible for Two Serogroup B Outbreaks on U.S. University Campuses to Serum Bactericidal Activity Elicited by the MenB-4C Vaccine.

Rossi R, Beernink PT, Giuntini S, Granoff DM.

Clin Vaccine Immunol. 2015 Dec;22(12):1227-34. doi: 10.1128/CVI.00474-15. Epub 2015 Sep 30.


Functional Analysis of the Human Antibody Response to Meningococcal Factor H Binding Protein.

Beernink PT, Giuntini S, Costa I, Lucas AH, Granoff DM.

MBio. 2015 Jun 23;6(3):e00842. doi: 10.1128/mBio.00842-15.


Binding of Complement Factor H (FH) Decreases Protective Anti-FH Binding Protein Antibody Responses of Infant Rhesus Macaques Immunized With a Meningococcal Serogroup B Vaccine.

Granoff DM, Costa I, Konar M, Giuntini S, Van Rompay KK, Beernink PT.

J Infect Dis. 2015 Sep 1;212(5):784-92. doi: 10.1093/infdis/jiv081. Epub 2015 Feb 12.


Binding of complement factor H to PorB3 and NspA enhances resistance of Neisseria meningitidis to anti-factor H binding protein bactericidal activity.

Giuntini S, Pajon R, Ram S, Granoff DM.

Infect Immun. 2015 Apr;83(4):1536-45. doi: 10.1128/IAI.02984-14. Epub 2015 Feb 2.


Multiparameter Flow Cytometry to Detect Hematogones and to Assess B-lymphocyte clonality in Bone Marrow Samples from Patients with Non-Hodgkin Lymphomas.

Carulli G, Ottaviano V, Guerri V, Giuntini S, Sammuri P, Ciancia EM, Azzarà A.

Hematol Rep. 2014 Jun 26;6(2):5381. doi: 10.4081/hr.2014.5381. eCollection 2014 Apr 22.


fH-dependent complement evasion by disease-causing meningococcal strains with absent fHbp genes or frameshift mutations.

Giuntini S, Vu DM, Granoff DM.

Vaccine. 2013 Aug 28;31(38):4192-9. doi: 10.1016/j.vaccine.2013.06.009. Epub 2013 Jun 17.


Multiparameter immunophenotyping by flow cytometry as a diagnostic tool in multiple myeloma and monoclonal gammopathy of undetermined significance.

Carulli G, Ottaviano V, Cannizzo E, Giuntini S, Manetti C, Ciancia EM, Azzarà A.

Clin Ter. 2012;163(5):387-92.


B-cell acute lymphoblastic leukemia with t(4;11)(q21;q23) in a young woman: evolution into mixed phenotype acute leukemia with additional chromosomal aberrations in the course of therapy.

Carulli G, Marini A, Ferreri MI, Azzarà A, Ottaviano V, Lari T, Rocco M, Giuntini S, Petrini M.

Hematol Rep. 2012 Jul 11;4(3):e15. doi: 10.4081/hr.2012.e15. Epub 2012 Sep 6.


Monoclonal antibodies to meningococcal factor H binding protein with overlapping epitopes and discordant functional activity.

Giuntini S, Beernink PT, Reason DC, Granoff DM.

PLoS One. 2012;7(3):e34272. doi: 10.1371/journal.pone.0034272. Epub 2012 Mar 26.


Boccioni's coin.

Giuntini S, Teja A.

Int J Hist Sport. 2011;28(3-4):393-409.


Complement-mediated bactericidal activity of anti-factor H binding protein monoclonal antibodies against the meningococcus relies upon blocking factor H binding.

Giuntini S, Reason DC, Granoff DM.

Infect Immun. 2011 Sep;79(9):3751-9. doi: 10.1128/IAI.05182-11. Epub 2011 Jun 27.


Combination of morphology, flow cytometry and PCR assay to detect bone marrow infiltration in B-cell non-Hodgkin's lymphomas.

Carulli G, Orciuolo E, Cannizzo E, Bianchi G, Giuntini S, Ottaviano V, Galimberti S, Marini A, Buda G, Ghimenti M, Petrini M.

Clin Ter. 2010;161(3):253-8.


Meningococcal outer membrane vesicle vaccines derived from mutant strains engineered to express factor H binding proteins from antigenic variant groups 1 and 2.

Koeberling O, Giuntini S, Seubert A, Granoff DM.

Clin Vaccine Immunol. 2009 Feb;16(2):156-62. doi: 10.1128/CVI.00403-08. Epub 2008 Dec 24.


Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients.

Lazzerini PE, Lorenzini S, Selvi E, Capecchi PL, Chindamo D, Bisogno S, Ghittoni R, Natale MR, Caporali F, Giuntini S, Marcolongo R, Galeazzi M, Laghi-Pasini F.

Clin Exp Rheumatol. 2007 Sep-Oct;25(5):696-700.


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