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Prediction of bloodstream infection caused by ESBL-producing Enterobacterales in patients with suspected community-onset sepsis.

Fröding I, Valik JK, Bolinder L, Nauclér P, Giske CG.

Int J Antimicrob Agents. 2019 Feb 16. pii: S0924-8579(19)30031-7. doi: 10.1016/j.ijantimicag.2019.02.008. [Epub ahead of print]


Dynamics of resistance plasmids in extended spectrum β-lactamase-producing Enterobacteriaceae during post-infection colonization.

Brolund A, Rajer F, Giske CG, Melefors Ö, Titelman E, Sandegren L.

Antimicrob Agents Chemother. 2019 Feb 11. pii: AAC.02201-18. doi: 10.1128/AAC.02201-18. [Epub ahead of print]


Minimum inhibitory concentrations of fluoroquinolones and pyrazinamide susceptibility correlate to clinical improvement in MDR-TB patients - a nationwide Swedish cohort study over two decades.

Davies Forsman L, Jonsson J, Wagrell C, Werngren J, Mansjö M, Wijkander M, Groenheit R, Hammar U, Giske CG, Schön T, Bruchfeld J.

Clin Infect Dis. 2018 Dec 18. doi: 10.1093/cid/ciy1068. [Epub ahead of print]


USA300 methicillin-resistant Staphylococcus aureus in Stockholm, Sweden, from 2008 to 2016.

Enström J, Fröding I, Giske CG, Ininbergs K, Bai X, Sandh G, Tollström UB, Ullberg M, Fang H.

PLoS One. 2018 Nov 7;13(11):e0205761. doi: 10.1371/journal.pone.0205761. eCollection 2018.


Performance of the EUCAST disc diffusion method and two MIC methods in detection of Enterobacteriaceae with reduced susceptibility to meropenem: the NordicAST CPE study.

Haldorsen B, Giske CG, Hansen DS, Orri Helgason K, Kahlmeter G, Löhr IH, Matuschek E, Österblad M, Rantakokko-Jalava K, Wang M, Småbrekke L, Samuelsen Ø, Sundsfjord A.

J Antimicrob Chemother. 2018 Oct 1;73(10):2905. doi: 10.1093/jac/dky339. No abstract available.


Performance of the EUCAST disc diffusion method and two MIC methods in detection of Enterobacteriaceae with reduced susceptibility to meropenem: the NordicAST CPE study.

Haldorsen B, Giske CG, Hansen DS, Helgason KO, Kahlmeter G, Löhr IH, Matuschek E, Österblad M, Rantakokko-Jalava K, Wang M, Småbrekke L, Samuelsen Ø, Sundsfjord A; NordicAST CPE Study Group .

J Antimicrob Chemother. 2018 Oct 1;73(10):2738-2747. doi: 10.1093/jac/dky276.


Temporal Dynamics and Risk Factors for Bloodstream Infection With Extended-spectrum β-Lactamase-producing Bacteria in Previously-colonized Individuals: National Population-based Cohort Study.

Isendahl J, Giske CG, Hammar U, Sparen P, Tegmark Wisell K, Ternhag A, Nauclér P.

Clin Infect Dis. 2019 Feb 1;68(4):641-649. doi: 10.1093/cid/ciy539.


Infection with high proportion of multidrug-resistant bacteria in conflict-related injuries is associated with poor outcomes and excess resource consumption: a cohort study of Syrian patients treated in Jordan.

Älgå A, Wong S, Shoaib M, Lundgren K, Giske CG, von Schreeb J, Malmstedt J.

BMC Infect Dis. 2018 May 22;18(1):233. doi: 10.1186/s12879-018-3149-y.


Invasive infection caused by Klebsiella pneumoniae is a disease affecting patients with high comorbidity and associated with high long-term mortality.

Vading M, Nauclér P, Kalin M, Giske CG.

PLoS One. 2018 Apr 6;13(4):e0195258. doi: 10.1371/journal.pone.0195258. eCollection 2018.


Molecular epidemiology of NDM-1- and OXA-48-producing Klebsiella pneumoniae in an Iranian hospital: clonal dissemination of ST11 and ST893.

Solgi H, Badmasti F, Giske CG, Aghamohammad S, Shahcheraghi F.

J Antimicrob Chemother. 2018 Jun 1;73(6):1517-1524. doi: 10.1093/jac/dky081.


Introduction of a hydrolysis probe PCR assay for high-throughput screening of methicillin-resistant Staphylococcus aureus with the ability to include or exclude detection of Staphylococcus argenteus.

Bogestam K, Vondracek M, Karlsson M, Fang H, Giske CG.

PLoS One. 2018 Feb 9;13(2):e0192782. doi: 10.1371/journal.pone.0192782. eCollection 2018.


Neonatal intestinal colonization with extended-spectrum β-lactamase-producing Enterobacteriaceae-a 5-year follow-up study.

Nordberg V, Jonsson K, Giske CG, Iversen A, Aspevall O, Jonsson B, Camporeale A, Norman M, Navér L.

Clin Microbiol Infect. 2018 Sep;24(9):1004-1009. doi: 10.1016/j.cmi.2017.12.028. Epub 2018 Jan 8.


MIC-based dose adjustment: facts and fables.

Mouton JW, Muller AE, Canton R, Giske CG, Kahlmeter G, Turnidge J.

J Antimicrob Chemother. 2018 Mar 1;73(3):564-568. doi: 10.1093/jac/dkx427.


Colistin antimicrobial susceptibility testing-can the slow and challenging be replaced by the rapid and convenient?

Giske CG, Kahlmeter G.

Clin Microbiol Infect. 2018 Feb;24(2):93-94. doi: 10.1016/j.cmi.2017.10.007. Epub 2017 Oct 21. No abstract available.


Emergence of carbapenem resistant Escherichia coli isolates producing blaNDM and blaOXA-48-like carried on IncA/C and IncL/M plasmids at two Iranian university hospitals.

Solgi H, Giske CG, Badmasti F, Aghamohammad S, Havaei SA, Sabeti S, Mostafavizadeh K, Shahcheraghi F.

Infect Genet Evol. 2017 Nov;55:318-323. doi: 10.1016/j.meegid.2017.10.003. Epub 2017 Oct 4.


Molecular characterization of intestinal carriage of carbapenem-resistant Enterobacteriaceae among inpatients at two Iranian university hospitals: first report of co-production of bla NDM-7 and bla OXA-48.

Solgi H, Badmasti F, Aminzadeh Z, Giske CG, Pourahmad M, Vaziri F, Havaei SA, Shahcheraghi F.

Eur J Clin Microbiol Infect Dis. 2017 Nov;36(11):2127-2135. doi: 10.1007/s10096-017-3035-3. Epub 2017 Jun 21.


Escherichia coli: an old friend with new tidings.

Vila J, Sáez-López E, Johnson JR, Römling U, Dobrindt U, Cantón R, Giske CG, Naas T, Carattoli A, Martínez-Medina M, Bosch J, Retamar P, Rodríguez-Baño J, Baquero F, Soto SM.

FEMS Microbiol Rev. 2016 Jul 1;40(4):437-463. doi: 10.1093/femsre/fuw005. Review.


Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study.

Grundmann H, Glasner C, Albiger B, Aanensen DM, Tomlinson CT, Andrasević AT, Cantón R, Carmeli Y, Friedrich AW, Giske CG, Glupczynski Y, Gniadkowski M, Livermore DM, Nordmann P, Poirel L, Rossolini GM, Seifert H, Vatopoulos A, Walsh T, Woodford N, Monnet DL; European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) Working Group.

Lancet Infect Dis. 2017 Feb;17(2):153-163. doi: 10.1016/S1473-3099(16)30257-2. Epub 2016 Nov 18.


14-Year Survey in a Swedish County Reveals a Pronounced Increase in Bloodstream Infections (BSI). Comorbidity - An Independent Risk Factor for Both BSI and Mortality.

Holmbom M, Giske CG, Fredrikson M, Östholm Balkhed Å, Claesson C, Nilsson LE, Hoffmann M, Hanberger H.

PLoS One. 2016 Nov 11;11(11):e0166527. doi: 10.1371/journal.pone.0166527. eCollection 2016.


Community carriage of ESBL-producing Escherichia coli is associated with strains of low pathogenicity: a Swedish nationwide study.

Ny S, Löfmark S, Börjesson S, Englund S, Ringman M, Bergström J, Nauclér P, Giske CG, Byfors S.

J Antimicrob Chemother. 2017 Feb;72(2):582-588. doi: 10.1093/jac/dkw419. Epub 2016 Oct 24.


Standard dosing of piperacillin and meropenem fail to achieve adequate plasma concentrations in ICU patients.

Petersson J, Giske CG, Eliasson E.

Acta Anaesthesiol Scand. 2016 Nov;60(10):1425-1436. doi: 10.1111/aas.12808. Epub 2016 Sep 21.


A randomized controlled study of 5 and 10 days treatment with phenoxymethylpenicillin for pharyngotonsillitis caused by streptococcus group A - a protocol study.

Skoog G, Edlund C, Giske CG, Mölstad S, Norman C, Sundvall PD, Hedin K.

BMC Infect Dis. 2016 Sep 13;16:484. doi: 10.1186/s12879-016-1813-7.


Frequent acquisition of low-virulence strains of ESBL-producing Escherichia coli in travellers.

Vading M, Kabir MH, Kalin M, Iversen A, Wiklund S, Nauclér P, Giske CG.

J Antimicrob Chemother. 2016 Dec;71(12):3548-3555. Epub 2016 Aug 26.


The IRIDICA PCR/Electrospray Ionization-Mass Spectrometry Assay on Bronchoalveolar Lavage for Bacterial Etiology in Mechanically Ventilated Patients with Suspected Pneumonia.

Strålin K, Ehn F, Giske CG, Ullberg M, Hedlund J, Petersson J, Spindler C, Özenci V.

PLoS One. 2016 Jul 27;11(7):e0159694. doi: 10.1371/journal.pone.0159694. eCollection 2016.


Evaluation of antibacterial activities of colistin, rifampicin and meropenem combinations against NDM-1-producing Klebsiella pneumoniae in 24 h in vitro time-kill experiments.

Lagerbäck P, Khine WW, Giske CG, Tängdén T.

J Antimicrob Chemother. 2016 Aug;71(8):2321-5. doi: 10.1093/jac/dkw213. Epub 2016 Jun 21.


Etiology of bone and joint infections: a case series of 363 consecutive patients from an orthopaedic infection unit.

Wallander K, Jorup-Rönström C, Ullberg M, Törnblom I, Ottosson C, Giske CG.

Infect Dis (Lond). 2016 Aug;48(8):618-25. doi: 10.1080/23744235.2016.1183814. Epub 2016 May 17.


Meropenem-clavulanate has high in vitro activity against multidrug-resistant Mycobacterium tuberculosis.

Davies Forsman L, Giske CG, Bruchfeld J, Schön T, Juréen P, Ängeby K.

Int J Mycobacteriol. 2015 Mar;4 Suppl 1:80-1. doi: 10.1016/j.ijmyco.2014.10.018. Epub 2014 Nov 11.


Metagenomic analysis of bloodstream infections in patients with acute leukemia and therapy-induced neutropenia.

Gyarmati P, Kjellander C, Aust C, Song Y, Öhrmalm L, Giske CG.

Sci Rep. 2016 Mar 21;6:23532. doi: 10.1038/srep23532.


Bloodstream infections in patients with chronic lymphocytic leukemia: a longitudinal single-center study.

Kjellander C, Björkholm M, Källman O, Giske CG, Weibull CE, Löve TJ, Landgren O, Kristinsson SY.

Ann Hematol. 2016 May;95(6):871-9. doi: 10.1007/s00277-016-2643-9. Epub 2016 Mar 15.


A two-centre evaluation of RAPIDEC® CARBA NP for carbapenemase detection in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter spp.

Kabir MH, Meunier D, Hopkins KL, Giske CG, Woodford N.

J Antimicrob Chemother. 2016 May;71(5):1213-6. doi: 10.1093/jac/dkv468. Epub 2016 Jan 13.


Susceptibility testing breakpoints for Mycobacterium tuberculosis categorize isolates with resistance mutations in gyrA as susceptible to fluoroquinolones: implications for MDR-TB treatment and the definition of XDR-TB.

Niward K, Ängeby K, Chryssanthou E, Paues J, Bruchfeld J, Jureen P, Giske CG, Kahlmeter G, Schön T.

J Antimicrob Chemother. 2016 Feb;71(2):333-8. doi: 10.1093/jac/dkv353. Epub 2015 Nov 3.


Successful international clones of blaCTX-M-15-producing Klebsiella pneumoniae with coexpression of plasmid-mediated quinolone resistance (PMQR) determinants in Tehran hospitals.

Nematzadeh S, Shahcheraghi F, Iversen A, Giske CG.

Diagn Microbiol Infect Dis. 2015 Dec;83(4):371-4. doi: 10.1016/j.diagmicrobio.2015.09.005. Epub 2015 Sep 11.


Bacterial Landscape of Bloodstream Infections in Neutropenic Patients via High Throughput Sequencing.

Gyarmati P, Kjellander C, Aust C, Kalin M, Öhrmalm L, Giske CG.

PLoS One. 2015 Aug 13;10(8):e0135756. doi: 10.1371/journal.pone.0135756. eCollection 2015.


Reviving old antibiotics.

Theuretzbacher U, Van Bambeke F, Cantón R, Giske CG, Mouton JW, Nation RL, Paul M, Turnidge JD, Kahlmeter G.

J Antimicrob Chemother. 2015 Aug;70(8):2177-81. doi: 10.1093/jac/dkv157. Epub 2015 Jun 10. Review.


The aetiology of paediatric bloodstream infections changes after pneumococcal vaccination and group B streptococcus prophylaxis.

Luthander J, Bennet R, Giske CG, Nilsson A, Eriksson M.

Acta Paediatr. 2015 Sep;104(9):933-9. doi: 10.1111/apa.13070. Epub 2015 Jul 21.


Contemporary resistance trends and mechanisms for the old antibiotics colistin, temocillin, fosfomycin, mecillinam and nitrofurantoin.

Giske CG.

Clin Microbiol Infect. 2015 Oct;21(10):899-905. doi: 10.1016/j.cmi.2015.05.022. Epub 2015 May 28. Review.


Carbapenemase-producing Enterobacteriaceae in Sweden 2007-2013: Experiences from seven years of systematic surveillance and mandatory reporting.

Löfmark S, Sjöström K, Mäkitalo B, Edquist P, Tegmark Wisell K, Giske CG.

Drug Resist Updat. 2015 May;20:29-38. doi: 10.1016/j.drup.2015.05.001. Epub 2015 May 11.


Meropenem-clavulanic acid has high in vitro activity against multidrug-resistant Mycobacterium tuberculosis.

Davies Forsman L, Giske CG, Bruchfeld J, Schön T, Juréen P, Ängeby K.

Antimicrob Agents Chemother. 2015;59(6):3630-2. doi: 10.1128/AAC.00171-15. Epub 2015 Mar 30.


Rapid increase in multidrug-resistant enteric bacilli blood stream infection after prostate biopsy - A 10-year population-based cohort study.

Aly M, Dyrdak R, Nordström T, Jalal S, Weibull CE, Giske CG, Grönberg H.

Prostate. 2015 Jun 15;75(9):947-56. doi: 10.1002/pros.22979. Epub 2015 Mar 23.


Knowledge and understanding of antibiotic resistance and the risk of becoming a carrier when travelling abroad: a qualitative study of Swedish travellers.

Wiklund S, Fagerberg I, Örtqvist Å, Vading M, Giske CG, Broliden K, Tammelin A.

Scand J Public Health. 2015 May;43(3):302-8. doi: 10.1177/1403494815571788. Epub 2015 Feb 23.


[Response times can be shortened in microbiological diagnosis of sepsis. Better opening hours in laboratories and active advice enables faster therapy].

Åkerlund A, Sundqvist M, Hanberger H, Åhrén C, Serrander L, Giske CG.

Lakartidningen. 2015 Feb 10;112. pii: C73S. Swedish.


Little difference between minimum inhibitory concentrations of Mycobacterium tuberculosis wild-type organisms determined with BACTEC MGIT 960 and Middlebrook 7H10.

Sturegård E, Ängeby KA, Werngren J, Juréen P, Kronvall G, Giske CG, Kahlmeter G, Schön T.

Clin Microbiol Infect. 2015 Feb;21(2):148.e5-7. doi: 10.1016/j.cmi.2014.08.021. Epub 2014 Oct 29.


Prevalence of community-acquired bacteraemia in Guinea-Bissau: an observational study.

Isendahl J, Manjuba C, Rodrigues A, Xu W, Henriques-Normark B, Giske CG, Nauclér P.

BMC Infect Dis. 2014 Dec 20;14:3859. doi: 10.1186/s12879-014-0715-9.


Surveillance of antimicrobial resistance among Escherichia coli in wastewater in Stockholm during 1 year: does it reflect the resistance trends in the society?

Kwak YK, Colque P, Byfors S, Giske CG, Möllby R, Kühn I.

Int J Antimicrob Agents. 2015 Jan;45(1):25-32. doi: 10.1016/j.ijantimicag.2014.09.016. Epub 2014 Oct 24.


Klebsiella variicola is a frequent cause of bloodstream infection in the stockholm area, and associated with higher mortality compared to K. pneumoniae.

Maatallah M, Vading M, Kabir MH, Bakhrouf A, Kalin M, Nauclér P, Brisse S, Giske CG.

PLoS One. 2014 Nov 26;9(11):e113539. doi: 10.1371/journal.pone.0113539. eCollection 2014.


Intra- and extracellular activities of trimethoprim-sulfamethoxazole against susceptible and multidrug-resistant Mycobacterium tuberculosis.

Davies Forsman L, Schön T, Simonsson US, Bruchfeld J, Larsson M, Juréen P, Sturegård E, Giske CG, Ängeby K.

Antimicrob Agents Chemother. 2014 Dec;58(12):7557-9. doi: 10.1128/AAC.02995-14. Epub 2014 Sep 22.


[New antibiotics with activity against multidrug-resistant enterobacteriaceae. Combination preparations are now being tested clinically].

Petropoulos EA, Hanberger H, Giske CG.

Lakartidningen. 2014 Jun 11-17;111(24):1050-1. Swedish. No abstract available.


Nuclease-assisted suppression of human DNA background in sepsis.

Song Y, Giske CG, Gille-Johnson P, Emanuelsson O, Lundeberg J, Gyarmati P.

PLoS One. 2014 Jul 30;9(7):e103610. doi: 10.1371/journal.pone.0103610. eCollection 2014.

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