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Items: 1 to 20 of 201


Sweetening the hallmarks of cancer: Galectins as multifunctional mediators of tumor progression.

Girotti MR, Salatino M, Dalotto-Moreno T, Rabinovich GA.

J Exp Med. 2020 Feb 3;217(2). pii: e20182041. doi: 10.1084/jem.20182041.


Ciliary neurotrophic factor signaling in the rat orbitofrontal cortex ameliorates stress-induced deficits in reversal learning.

Girotti M, Silva JD, George CM, Morilak DA.

Neuropharmacology. 2019 Dec 1;160:107791. doi: 10.1016/j.neuropharm.2019.107791. Epub 2019 Sep 22.


Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation.

Segovia M, Russo S, Jeldres M, Mahmoud YD, Perez V, Duhalde M, Charnet P, Rousset M, Victoria S, Veigas F, Louvet C, Vanhove B, Floto RA, Anegon I, Cuturi MC, Girotti MR, Rabinovich GA, Hill M.

Cancer Cell. 2019 May 13;35(5):767-781.e6. doi: 10.1016/j.ccell.2019.04.003.


Body size and social status in medieval Alba (Cuneo), Italy.

Weiss NM, Vercellotti G, Boano R, Girotti M, Stout SD.

Am J Phys Anthropol. 2019 Mar;168(3):595-605. doi: 10.1002/ajpa.23776. Epub 2019 Feb 4.


[Immunotherapy in cancer. Current prospects, challenges and new horizons].

Dalotto-Moreno T, Blidner AG, Girotti MR, Maller SM, Rabinovich GA.

Medicina (B Aires). 2018;78(5):336-348. Review. Spanish.


Spatial diffusion of surnames by long transhumance routes between highland and lowland: A study in Sardinia.

Orrù A, De Iasio S, Frederic P, Girotti M, Boano R, Sanna E.

Homo. 2018 May;69(3):127-138. doi: 10.1016/j.jchb.2018.06.006. Epub 2018 Jul 13.


Induction of chromosomal aberrations and micronuclei by 2-hydroxy-4-methoxybenzophenone (oxybenzone) in human lymphocytes.

Santovito A, Ruberto S, Galli G, Menghi C, Girotti M, Cervella P.

Drug Chem Toxicol. 2019 Jul;42(4):378-385. doi: 10.1080/01480545.2018.1455206. Epub 2018 Apr 12.


Glycans Pave the Way for Immunotherapy in Triple-Negative Breast Cancer.

Salatino M, Girotti MR, Rabinovich GA.

Cancer Cell. 2018 Feb 12;33(2):155-157. doi: 10.1016/j.ccell.2018.01.015.


Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients.

Valpione S, Gremel G, Mundra P, Middlehurst P, Galvani E, Girotti MR, Lee RJ, Garner G, Dhomen N, Lorigan PC, Marais R.

Eur J Cancer. 2018 Jan;88:1-9. doi: 10.1016/j.ejca.2017.10.029. Epub 2017 Nov 23.


Prefrontal cortex executive processes affected by stress in health and disease.

Girotti M, Adler SM, Bulin SE, Fucich EA, Paredes D, Morilak DA.

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jul 13;85:161-179. doi: 10.1016/j.pnpbp.2017.07.004. Epub 2017 Jul 6. Review.


mTOR drives cerebral blood flow and memory deficits in LDLR-/- mice modeling atherosclerosis and vascular cognitive impairment.

Jahrling JB, Lin AL, DeRosa N, Hussong SA, Van Skike CE, Girotti M, Javors M, Zhao Q, Maslin LA, Asmis R, Galvan V.

J Cereb Blood Flow Metab. 2018 Jan;38(1):58-74. doi: 10.1177/0271678X17705973. Epub 2017 May 17.


Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models.

Khandelwal G, Girotti MR, Smowton C, Taylor S, Wirth C, Dynowski M, Frese KK, Brady G, Dive C, Marais R, Miller C.

Mol Cancer Res. 2017 Aug;15(8):1012-1016. doi: 10.1158/1541-7786.MCR-16-0431. Epub 2017 Apr 25.


Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma.

Girotti MR, Lopes F, Preece N, Niculescu-Duvaz D, Zambon A, Davies L, Whittaker S, Saturno G, Viros A, Pedersen M, Suijkerbuijk BMJM, Menard D, McLeary R, Johnson L, Fish L, Ejiama S, Sanchez-Laorden B, Hohloch J, Carragher N, Macleod K, Ashton G, Marusiak AA, Fusi A, Brognard J, Frame M, Lorigan P, Marais R, Springer C.

Cancer Cell. 2017 Mar 13;31(3):466. doi: 10.1016/j.ccell.2017.02.007. No abstract available.


What Is the Real Impact of Urinary Incontinence on Female Sexual Dysfunction? A Case Control Study.

Felippe MR, Zambon JP, Girotti ME, Burti JS, Hacad CR, Cadamuro L, Almeida F.

Sex Med. 2017 Mar;5(1):e54-e60. doi: 10.1016/j.esxm.2016.09.001. Epub 2017 Jan 10.


Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells.

Spender LC, Ferguson GJ, Liu S, Cui C, Girotti MR, Sibbet G, Higgs EB, Shuttleworth MK, Hamilton T, Lorigan P, Weller M, Vincent DF, Sansom OJ, Frame M, Dijke PT, Marais R, Inman GJ.

Oncotarget. 2016 Dec 13;7(50):81995-82012. doi: 10.18632/oncotarget.13226.


Ketamine Corrects Stress-Induced Cognitive Dysfunction through JAK2/STAT3 Signaling in the Orbitofrontal Cortex.

Patton MS, Lodge DJ, Morilak DA, Girotti M.

Neuropsychopharmacology. 2017 May;42(6):1220-1230. doi: 10.1038/npp.2016.236. Epub 2016 Oct 17.


Distinct subclonal tumour responses to therapy revealed by circulating cell-free DNA.

Gremel G, Lee RJ, Girotti MR, Mandal AK, Valpione S, Garner G, Ayub M, Wood S, Rothwell DG, Fusi A, Wallace A, Brady G, Dive C, Dhomen N, Lorigan P, Marais R.

Ann Oncol. 2016 Oct;27(10):1959-65. doi: 10.1093/annonc/mdw278. Epub 2016 Aug 8.


So You Can Teach Old Fibroblasts New Tricks.

Virós A, Girotti MR, Marais R.

Cancer Discov. 2016 Jun;6(6):581-3. doi: 10.1158/2159-8290.CD-16-0503.


Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy.

Smith MP, Brunton H, Rowling EJ, Ferguson J, Arozarena I, Miskolczi Z, Lee JL, Girotti MR, Marais R, Levesque MP, Dummer R, Frederick DT, Flaherty KT, Cooper ZA, Wargo JA, Wellbrock C.

Cancer Cell. 2016 Mar 14;29(3):270-284. doi: 10.1016/j.ccell.2016.02.003.


Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma.

Girotti MR, Gremel G, Lee R, Galvani E, Rothwell D, Viros A, Mandal AK, Lim KH, Saturno G, Furney SJ, Baenke F, Pedersen M, Rogan J, Swan J, Smith M, Fusi A, Oudit D, Dhomen N, Brady G, Lorigan P, Dive C, Marais R.

Cancer Discov. 2016 Mar;6(3):286-99. doi: 10.1158/2159-8290.CD-15-1336. Epub 2015 Dec 29.

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