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Items: 1 to 50 of 186

1.

Antidepressive effects of targeting ELK-1 signal transduction.

Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JP, Grenier J, Ibrahim EC, El Khoury MA, Tse YC, Mongredien R, Barbé A, de Macedo CEA, Jaworski W, Bochereau A, Orrico A, Isingrini E, Guinaudie C, Mikasova L, Louis F, Gautron S, Groc L, Massaad C, Yildirim F, Vialou V, Dumas S, Marti F, Mechawar N, Morice E, Wong TP, Caboche J, Turecki G, Giros B, Tzavara ET.

Nat Med. 2018 May;24(5):591-597. doi: 10.1038/s41591-018-0011-0. Epub 2018 May 7.

PMID:
29736027
2.

Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor.

Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B.

Neuroimage. 2018 Aug 1;176:226-238. doi: 10.1016/j.neuroimage.2018.04.054. Epub 2018 Apr 26.

PMID:
29704613
3.

Cocaine increases dopaminergic connectivity in the nucleus accumbens.

Dos Santos M, Cahill EN, Bo GD, Vanhoutte P, Caboche J, Giros B, Heck N.

Brain Struct Funct. 2018 Mar;223(2):913-923. doi: 10.1007/s00429-017-1532-x. Epub 2017 Oct 12.

PMID:
29027032
4.

Genetic elimination of dopamine vesicular stocks in the nigrostriatal pathway replicates Parkinson's disease motor symptoms without neuronal degeneration in adult mice.

Isingrini E, Guinaudie C, C Perret L, Rainer Q, Moquin L, Gratton A, Giros B.

Sci Rep. 2017 Sep 29;7(1):12432. doi: 10.1038/s41598-017-12810-9.

5.

Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide.

Mahar I, Labonte B, Yogendran S, Isingrini E, Perret L, Davoli MA, Rachalski A, Giros B, Turecki G, Mechawar N.

Transl Psychiatry. 2017 Sep 26;7(9):e1243. doi: 10.1038/tp.2017.214.

6.

Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions.

Erdozain AM, De Gois S, Bernard V, Gorgievski V, Pietrancosta N, Dumas S, Macedo CE, Vanhoutte P, Ortega JE, Meana JJ, Tzavara ET, Vialou V, Giros B.

Neuropsychopharmacology. 2018 Apr;43(5):1041-1051. doi: 10.1038/npp.2017.217. Epub 2017 Sep 14.

PMID:
28905875
7.

Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide.

Mahar I, Labonte B, Yogendran S, Isingrini E, Perret L, Davoli MA, Rachalski A, Giros B, Turecki G, Mechawar N.

Transl Psychiatry. 2017 Jul 4;7(7):e1161. doi: 10.1038/tp.2017.132. Erratum in: Transl Psychiatry. 2017 Sep 26;7(9):e1243.

8.

VMAT2-Mediated Neurotransmission from Midbrain Leptin Receptor Neurons in Feeding Regulation.

Xu Y, Lu Y, Xu P, Mangieri LR, Isingrini E, Xu Y, Giros B, Tong Q.

eNeuro. 2017 May 26;4(3). pii: ENEURO.0083-17.2017. doi: 10.1523/ENEURO.0083-17.2017. eCollection 2017 May-Jun.

9.

Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells.

Fasano C, Rocchetti J, Pietrajtis K, Zander JF, Manseau F, Sakae DY, Marcus-Sells M, Ramet L, Morel LJ, Carrel D, Dumas S, Bolte S, Bernard V, Vigneault E, Goutagny R, Ahnert-Hilger G, Giros B, Daumas S, Williams S, El Mestikawy S.

Front Cell Neurosci. 2017 May 16;11:140. doi: 10.3389/fncel.2017.00140. eCollection 2017.

10.

Non-linear dose-response of aluminium hydroxide adjuvant particles: Selective low dose neurotoxicity.

Crépeaux G, Eidi H, David MO, Baba-Amer Y, Tzavara E, Giros B, Authier FJ, Exley C, Shaw CA, Cadusseau J, Gherardi RK.

Toxicology. 2017 Jan 15;375:48-57. doi: 10.1016/j.tox.2016.11.018. Epub 2016 Nov 28.

PMID:
27908630
11.

Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons.

Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B.

Nat Neurosci. 2016 Apr;19(4):560-3. doi: 10.1038/nn.4245. Epub 2016 Feb 15.

PMID:
26878672
12.

Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.

De Magalhaes Filho CD, Kappeler L, Dupont J, Solinc J, Villapol S, Denis C, Nosten-Bertrand M, Billard JM, Blaise A, Tronche F, Giros B, Charriaut-Marlangue C, Aïd S, Le Bouc Y, Holzenberger M.

J Cereb Blood Flow Metab. 2017 Feb;37(2):396-412. doi: 10.1177/0271678X15626718. Epub 2016 Jul 20.

13.

Selective genetic disruption of dopaminergic, serotonergic and noradrenergic neurotransmission: insights into motor, emotional and addictive behaviour.

Isingrini E, Perret L, Rainer Q, Sagueby S, Moquin L, Gratton A, Giros B.

J Psychiatry Neurosci. 2016 Apr;41(3):169-81.

14.

Highly delayed systemic translocation of aluminum-based adjuvant in CD1 mice following intramuscular injections.

Crépeaux G, Eidi H, David MO, Tzavara E, Giros B, Exley C, Curmi PA, Shaw CA, Gherardi RK, Cadusseau J.

J Inorg Biochem. 2015 Nov;152:199-205. doi: 10.1016/j.jinorgbio.2015.07.004. Epub 2015 Jul 22.

PMID:
26384437
15.

Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism.

Pilorge M, Fassier C, Le Corronc H, Potey A, Bai J, De Gois S, Delaby E, Assouline B, Guinchat V, Devillard F, Delorme R, Nygren G, Råstam M, Meier JC, Otani S, Cheval H, James VM, Topf M, Dear TN, Gillberg C, Leboyer M, Giros B, Gautron S, Hazan J, Harvey RJ, Legendre P, Betancur C.

Mol Psychiatry. 2016 Jul;21(7):936-45. doi: 10.1038/mp.2015.139. Epub 2015 Sep 15.

16.

The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens.

Sakae DY, Marti F, Lecca S, Vorspan F, Martín-García E, Morel LJ, Henrion A, Gutiérrez-Cuesta J, Besnard A, Heck N, Herzog E, Bolte S, Prado VF, Prado MA, Bellivier F, Eap CB, Crettol S, Vanhoutte P, Caboche J, Gratton A, Moquin L, Giros B, Maldonado R, Daumas S, Mameli M, Jamain S, El Mestikawy S.

Mol Psychiatry. 2015 Nov;20(11):1448-59. doi: 10.1038/mp.2015.104. Epub 2015 Aug 4.

PMID:
26239290
17.

Ctr9, a Protein in the Transcription Complex Paf1, Regulates Dopamine Transporter Activity at the Plasma Membrane.

De Gois S, Slama P, Pietrancosta N, Erdozain AM, Louis F, Bouvrais-Veret C, Daviet L, Giros B.

J Biol Chem. 2015 Jul 17;290(29):17848-62. doi: 10.1074/jbc.M115.646315. Epub 2015 Jun 5.

18.

GABAB receptor cell-surface export is controlled by an endoplasmic reticulum gatekeeper.

Doly S, Shirvani H, Gäta G, Meye FJ, Emerit MB, Enslen H, Achour L, Pardo-Lopez L, Yang SK, Armand V, Gardette R, Giros B, Gassmann M, Bettler B, Mameli M, Darmon M, Marullo S.

Mol Psychiatry. 2016 Apr;21(4):480-90. doi: 10.1038/mp.2015.72. Epub 2015 Jun 2.

19.

A highly tunable dopaminergic oscillator generates ultradian rhythms of behavioral arousal.

Blum ID, Zhu L, Moquin L, Kokoeva MV, Gratton A, Giros B, Storch KF.

Elife. 2014 Dec 29;3. doi: 10.7554/eLife.05105.

20.

Brain organic cation transporter 2 controls response and vulnerability to stress and GSK3β signaling.

Couroussé T, Bacq A, Belzung C, Guiard B, Balasse L, Louis F, Le Guisquet AM, Gardier AM, Schinkel AH, Giros B, Gautron S.

Mol Psychiatry. 2015 Jul;20(7):889-900. doi: 10.1038/mp.2014.86. Epub 2014 Aug 5.

PMID:
25092247
21.

Presynaptic D2 dopamine receptors control long-term depression expression and memory processes in the temporal hippocampus.

Rocchetti J, Isingrini E, Dal Bo G, Sagheby S, Menegaux A, Tronche F, Levesque D, Moquin L, Gratton A, Wong TP, Rubinstein M, Giros B.

Biol Psychiatry. 2015 Mar 15;77(6):513-25. doi: 10.1016/j.biopsych.2014.03.013. Epub 2014 Mar 20.

PMID:
24742619
22.

Morphometric characterization of microglial phenotypes in human cerebral cortex.

Torres-Platas SG, Comeau S, Rachalski A, Bo GD, Cruceanu C, Turecki G, Giros B, Mechawar N.

J Neuroinflammation. 2014 Jan 21;11:12. doi: 10.1186/1742-2094-11-12.

23.

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

Manitt C, Eng C, Pokinko M, Ryan RT, Torres-Berrío A, Lopez JP, Yogendran SV, Daubaras MJ, Grant A, Schmidt ER, Tronche F, Krimpenfort P, Cooper HM, Pasterkamp RJ, Kolb B, Turecki G, Wong TP, Nestler EJ, Giros B, Flores C.

Transl Psychiatry. 2013 Dec 17;3:e338. doi: 10.1038/tp.2013.105.

24.

Modulation of hippocampus-prefrontal cortex synaptic transmission and disruption of executive cognitive functions by MK-801.

Blot K, Kimura S, Bai J, Kemp A, Manahan-Vaughan D, Giros B, Tzavara E, Otani S.

Cereb Cortex. 2015 May;25(5):1348-61. doi: 10.1093/cercor/bht329. Epub 2013 Dec 4.

PMID:
24304584
25.

The dopamine D1 receptor agonist SKF 38393 improves temporal order memory performance in maternally deprived rats.

Lejeune S, Dourmap N, Martres MP, Giros B, Daugé V, Naudon L.

Neurobiol Learn Mem. 2013 Nov;106:268-73. doi: 10.1016/j.nlm.2013.10.005. Epub 2013 Oct 17.

PMID:
24140426
26.

Doublecortin knockout mice show normal hippocampal-dependent memory despite CA3 lamination defects.

Germain J, Bruel-Jungerman E, Grannec G, Denis C, Lepousez G, Giros B, Francis F, Nosten-Bertrand M.

PLoS One. 2013 Sep 20;8(9):e74992. doi: 10.1371/journal.pone.0074992. eCollection 2013.

27.

Vulnerability to opiate intake in maternally deprived rats: implication of MeCP2 and of histone acetylation.

Tesone-Coelho C, Morel LJ, Bhatt J, Estevez L, Naudon L, Giros B, Zwiller J, Daugé V.

Addict Biol. 2015 Jan;20(1):120-31. doi: 10.1111/adb.12084. Epub 2013 Aug 26.

PMID:
23980619
28.

Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin.

Diaz SL, Narboux-Nême N, Trowbridge S, Scotto-Lomassese S, Kleine Borgmann FB, Jessberger S, Giros B, Maroteaux L, Deneris E, Gaspar P.

Eur J Neurosci. 2013 Sep;38(5):2650-8. doi: 10.1111/ejn.12297. Epub 2013 Jul 10.

29.

Postnatal growth defects in mice with constitutive depletion of central serotonin.

Narboux-Nême N, Angenard G, Mosienko V, Klempin F, Pitychoutis PM, Deneris E, Bader M, Giros B, Alenina N, Gaspar P.

ACS Chem Neurosci. 2013 Jan 16;4(1):171-81. doi: 10.1021/cn300165x. Epub 2012 Dec 15.

30.

Inhibition of dopamine transporter activity impairs synaptic depression in rat prefrontal cortex through over-stimulation of D1 receptors.

Bai J, Blot K, Tzavara E, Nosten-Bertrand M, Giros B, Otani S.

Cereb Cortex. 2014 Apr;24(4):945-55. doi: 10.1093/cercor/bhs376. Epub 2012 Dec 12.

PMID:
23236206
31.

In vivo occupancy of dopamine D3 receptors by antagonists produces neurochemical and behavioral effects of potential relevance to attention-deficit-hyperactivity disorder.

Barth V, Need AB, Tzavara ET, Giros B, Overshiner C, Gleason SD, Wade M, Johansson AM, Perry K, Nomikos GG, Witkin JM.

J Pharmacol Exp Ther. 2013 Feb;344(2):501-10. doi: 10.1124/jpet.112.198895. Epub 2012 Nov 29.

32.

Possible involvement of endocannabinoids in the increase of morphine consumption in maternally deprived rat.

Naudon L, Piscitelli F, Giros B, Di Marzo V, Daugé V.

Neuropharmacology. 2013 Feb;65:193-9. doi: 10.1016/j.neuropharm.2012.10.008. Epub 2012 Oct 23.

PMID:
23089638
33.

Both chronic treatments by epothilone D and fluoxetine increase the short-term memory and differentially alter the mood status of STOP/MAP6 KO mice.

Fournet V, de Lavilléon G, Schweitzer A, Giros B, Andrieux A, Martres MP.

J Neurochem. 2012 Dec;123(6):982-96. doi: 10.1111/jnc.12027. Epub 2012 Oct 25.

34.

Maternal deprivation induces deficits in temporal memory and cognitive flexibility and exaggerates synaptic plasticity in the rat medial prefrontal cortex.

Baudin A, Blot K, Verney C, Estevez L, Santamaria J, Gressens P, Giros B, Otani S, Daugé V, Naudon L.

Neurobiol Learn Mem. 2012 Oct;98(3):207-14. doi: 10.1016/j.nlm.2012.08.004. Epub 2012 Aug 24.

PMID:
22922490
35.

Interaction of antidepressant and antipsychotic drugs with the human organic cation transporters hOCT1, hOCT2 and hOCT3.

Haenisch B, Drescher E, Thiemer L, Xin H, Giros B, Gautron S, Bönisch H.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Oct;385(10):1017-23. doi: 10.1007/s00210-012-0781-8. Epub 2012 Jul 18.

PMID:
22806583
36.

Interactions between the cannabinoid and dopaminergic systems: evidence from animal studies.

El Khoury MA, Gorgievski V, Moutsimilli L, Giros B, Tzavara ET.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Jul 2;38(1):36-50. doi: 10.1016/j.pnpbp.2011.12.005. Epub 2012 Jan 20. Review.

PMID:
22300746
37.

L-DOPA impairs proteasome activity in parkinsonism through D1 dopamine receptor.

Berthet A, Bezard E, Porras G, Fasano S, Barroso-Chinea P, Dehay B, Martinez A, Thiolat ML, Nosten-Bertrand M, Giros B, Baufreton J, Li Q, Bloch B, Martin-Negrier ML.

J Neurosci. 2012 Jan 11;32(2):681-91. doi: 10.1523/JNEUROSCI.1541-11.2012.

38.

The deletion of STOP/MAP6 protein in mice triggers highly altered mood and impaired cognitive performances.

Fournet V, Schweitzer A, Chevarin C, Deloulme JC, Hamon M, Giros B, Andrieux A, Martres MP.

J Neurochem. 2012 Apr;121(1):99-114. doi: 10.1111/j.1471-4159.2011.07615.x. Epub 2012 Jan 23.

39.

Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801.

Farley S, Dumas S, El Mestikawy S, Giros B.

Neuropharmacology. 2012 Jan;62(1):503-17. doi: 10.1016/j.neuropharm.2011.09.010. Epub 2011 Sep 17.

PMID:
21945287
40.

Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences.

Narboux-Nême N, Sagné C, Doly S, Diaz SL, Martin CB, Angenard G, Martres MP, Giros B, Hamon M, Lanfumey L, Gaspar P, Mongeau R.

Neuropsychopharmacology. 2011 Nov;36(12):2538-50. doi: 10.1038/npp.2011.142. Epub 2011 Aug 3.

41.

Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response.

Bacq A, Balasse L, Biala G, Guiard B, Gardier AM, Schinkel A, Louis F, Vialou V, Martres MP, Chevarin C, Hamon M, Giros B, Gautron S.

Mol Psychiatry. 2012 Sep;17(9):926-39. doi: 10.1038/mp.2011.87. Epub 2011 Jul 19.

PMID:
21769100
42.

Endogenous morphine-like compound immunoreactivity increases in parkinsonism.

Charron G, Doudnikoff E, Laux A, Berthet A, Porras G, Canron MH, Barroso-Chinea P, Li Q, Qin C, Nosten-Bertrand M, Giros B, Delalande F, Van Dorsselaer A, Vital A, Goumon Y, Bezard E.

Brain. 2011 Aug;134(Pt 8):2321-38. doi: 10.1093/brain/awr166. Epub 2011 Jul 8.

PMID:
21742735
43.

Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring.

Naef L, Moquin L, Dal Bo G, Giros B, Gratton A, Walker CD.

Neuroscience. 2011 Mar 10;176:225-36. doi: 10.1016/j.neuroscience.2010.12.037. Epub 2010 Dec 25.

PMID:
21187125
44.

Early stress leads to effects on estrous cycle and differential responses to stress.

Mourlon V, Naudon L, Giros B, Crumeyrolle-Arias M, Daugé V.

Physiol Behav. 2011 Mar 1;102(3-4):304-10. doi: 10.1016/j.physbeh.2010.11.003. Epub 2010 Nov 6.

PMID:
21059366
45.

The deletion of the microtubule-associated STOP protein affects the serotonergic mouse brain network.

Fournet V, Jany M, Fabre V, Chali F, Orsal D, Schweitzer A, Andrieux A, Messanvi F, Giros B, Hamon M, Lanfumey L, Deloulme JC, Martres MP.

J Neurochem. 2010 Dec;115(6):1579-94. doi: 10.1111/j.1471-4159.2010.07064.x. Epub 2010 Nov 19.

46.

Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway.

Fassier C, Hutt JA, Scholpp S, Lumsden A, Giros B, Nothias F, Schneider-Maunoury S, Houart C, Hazan J.

Nat Neurosci. 2010 Nov;13(11):1380-7. doi: 10.1038/nn.2662. Epub 2010 Oct 10.

PMID:
20935645
47.

Rose Bengal analogs and vesicular glutamate transporters (VGLUTs).

Pietrancosta N, Kessler A, Favre-Besse FC, Triballeau N, Quentin T, Giros B, El Mestikawy S, Acher FC.

Bioorg Med Chem. 2010 Sep 15;18(18):6922-33. doi: 10.1016/j.bmc.2010.06.069. Epub 2010 Jun 25.

PMID:
20708942
48.

Maternal deprivation induces depressive-like behaviours only in female rats.

Mourlon V, Baudin A, Blanc O, Lauber A, Giros B, Naudon L, Daugé V.

Behav Brain Res. 2010 Dec 1;213(2):278-87. doi: 10.1016/j.bbr.2010.05.017. Epub 2010 May 19.

PMID:
20488211
49.

Inhibitory and facilitory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human alpha 1- and alpha 2-adrenoceptor subtypes.

Amphoux A, Millan MJ, Cordi A, Bönisch H, Vialou V, Mannoury la Cour C, Dupuis DS, Giros B, Gautron S.

Eur J Pharmacol. 2010 May 25;634(1-3):1-9. doi: 10.1016/j.ejphar.2010.02.012. Epub 2010 Feb 17.

PMID:
20170649
50.

VGLUT3 (vesicular glutamate transporter type 3) contribution to the regulation of serotonergic transmission and anxiety.

Amilhon B, Lepicard E, Renoir T, Mongeau R, Popa D, Poirel O, Miot S, Gras C, Gardier AM, Gallego J, Hamon M, Lanfumey L, Gasnier B, Giros B, El Mestikawy S.

J Neurosci. 2010 Feb 10;30(6):2198-210. doi: 10.1523/JNEUROSCI.5196-09.2010.

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