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Items: 1 to 50 of 221

1.

Effects of intravenous administration of pirfenidone on horses with experimentally induced endotoxemia.

Poulin Braim AE, MacDonald MH, Bruss ML, Grattendick KJ, Giri SN, Margolin SB.

Am J Vet Res. 2009 Aug;70(8):1031-42. doi: 10.2460/ajvr.70.8.1031.

PMID:
19645586
4.

Pharmacokinetics and clinical effects of pirfenidone administered intravenously in horses.

Braim AE, Macdonald MH, Bruss ML, Stanley SD, Giri JK, Giri SN.

Am J Vet Res. 2008 Jul;69(7):952-60. doi: 10.2460/ajvr.69.7.952.

PMID:
18593250
6.

Effects of three anti-TNF-alpha drugs: etanercept, infliximab and pirfenidone on release of TNF-alpha in medium and TNF-alpha associated with the cell in vitro.

Grattendick KJ, Nakashima JM, Feng L, Giri SN, Margolin SB.

Int Immunopharmacol. 2008 May;8(5):679-87. doi: 10.1016/j.intimp.2008.01.013. Epub 2008 Feb 11.

PMID:
18387510
7.

Pharmacokinetics and metabolism of intravenous pirfenidone in sheep.

Bruss ML, Stanley SD, Margolin SB, Giri SN.

Biopharm Drug Dispos. 2008 Mar;29(2):119-26. doi: 10.1002/bdd.595.

PMID:
18176939
8.

Antirheumatic effect of pirfenidone in a double blind clinical pilot trial in humans.

Pesce E, Struma E, Giri SN, Margolin SB.

Res Commun Mol Pathol Pharmacol. 2004;115-116:39-48.

PMID:
17564304
9.

Influence of pirfenidone on airway hyperresponsiveness and inflammation in a Brown-Norway rat model of asthma.

Mansoor JK, Decile KC, Giri SN, Pinkerton KE, Walby WF, Bratt JM, Grewal H, Margolin SB, Schelegle ES.

Pulm Pharmacol Ther. 2007;20(6):660-8. Epub 2006 Sep 15.

PMID:
17049446
10.
11.

Modulation of articular chondrocyte activity by pirfenidone.

Benton HP, Esquivel AV, Rice AD, Giri SN.

Res Commun Mol Pathol Pharmacol. 2003;113-114:275-88.

PMID:
15686126
12.

Pharmacokinetics of orally administered pirfenidone in male and female beagles.

Bruss ML, Margolin SB, Giri SN.

J Vet Pharmacol Ther. 2004 Oct;27(5):361-7.

PMID:
15500575
13.

Effects of pirfenidone on the generation of reactive oxygen species in vitro.

Giri SN, Leonard S, Shi X, Margolin SB, Vallyathan V.

J Environ Pathol Toxicol Oncol. 1999;18(3):169-77.

PMID:
15281229
14.

Amelioration of doxorubicin-induced cardiac and renal toxicity by pirfenidone in rats.

Giri SN, Al-Bayati MA, Du X, Schelegle E, Mohr FC, Margolin SB.

Cancer Chemother Pharmacol. 2004 Feb;53(2):141-50. Epub 2003 Oct 15.

PMID:
14564477
15.
16.

Novel pharmacological approaches to manage interstitial lung fibrosis in the twenty-first century.

Giri SN.

Annu Rev Pharmacol Toxicol. 2003;43:73-95. Epub 2002 Jan 10. Review.

PMID:
12540741
17.

Abrogation of bleomycin-induced lung fibrosis by nitric oxide synthase inhibitor, aminoguanidine in mice.

Giri SN, Biring I, Nguyen T, Wang Q, Hyde DM.

Nitric Oxide. 2002 Sep;7(2):109-18.

PMID:
12223180
18.
19.

Effect of pirfenidone against vanadate-induced kidney fibrosis in rats.

Al-Bayati MA, Xie Y, Mohr FC, Margolin SB, Giri SN.

Biochem Pharmacol. 2002 Aug 1;64(3):517-25.

PMID:
12147304
20.

Pharmacokinetics and metabolism of a novel antifibrotic drug pirfenidone, in mice following intravenous administration.

Giri SN, Wang Q, Xie Y, Lango J, Morin D, Margolin SB, Buckpitt AR.

Biopharm Drug Dispos. 2002 Jul;23(5):203-11.

PMID:
12116052
21.

Suppression of bleomycin-induced increased production of nitric oxide and NF-kB activation by treatment with taurine and niacin.

Giri SN, Gurujeyalakshmi G, Wang Y.

Adv Exp Med Biol. 2000;483:545-61. No abstract available.

PMID:
11787640
22.

Effect of antibody against integrin alpha4 on bleomycin-induced pulmonary fibrosis in mice.

Wang Q, Wang Y, Hyde DM, Gotwals PJ, Lobb RR, Ryan ST, Giri SN.

Biochem Pharmacol. 2000 Dec 15;60(12):1949-58.

PMID:
11108812
23.

Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin.

Gurujeyalakshmi G, Wang Y, Giri SN.

Nitric Oxide. 2000 Aug;4(4):399-411.

PMID:
10944425
24.

Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation.

Iyer SN, Hyde DM, Giri SN.

Inflammation. 2000 Oct;24(5):477-91.

PMID:
10921510
25.

Characterization of [(3)H]ryanodine binding sites in mammalian lung.

Wild JS, Giri SN, Moore R, Pessah IN.

Arch Biochem Biophys. 2000 Jul 1;379(1):109-18.

PMID:
10864448
26.
27.
28.

Reduction of bleomycin induced lung fibrosis by transforming growth factor beta soluble receptor in hamsters.

Wang Q, Wang Y, Hyde DM, Gotwals PJ, Koteliansky VE, Ryan ST, Giri SN.

Thorax. 1999 Sep;54(9):805-12.

29.
30.

Pirfenidone inhibits PDGF isoforms in bleomycin hamster model of lung fibrosis at the translational level.

Gurujeyalakshmi G, Hollinger MA, Giri SN.

Am J Physiol. 1999 Feb;276(2 Pt 1):L311-8.

PMID:
9950894
31.

Regulation of transforming growth factor-beta1 mRNA expression by taurine and niacin in the bleomycin hamster model of lung fibrosis.

Gurujeyalakshmi G, Hollinger MA, Giri SN.

Am J Respir Cell Mol Biol. 1998 Mar;18(3):334-42.

PMID:
9490651
32.

Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three-dose bleomycin-hamster model.

Iyer SN, Margolin SB, Hyde DM, Giri SN.

Exp Lung Res. 1998 Jan-Feb;24(1):119-32.

PMID:
9457473
33.

Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis.

Giri SN, Hyde DM, Braun RK, Gaarde W, Harper JR, Pierschbacher MD.

Biochem Pharmacol. 1997 Dec 1;54(11):1205-16.

PMID:
9416971
34.

Histamine and eicosanoid levels in plasma and peripheral blood leucocyte cultures during experimental infection of cattle with bluetongue virus serotype 11.

OdeĆ³n AC, Giri SN, de la Concha-Bermejillo A, Osburn BI.

Zentralbl Veterinarmed B. 1997 Oct;44(8):449-60.

PMID:
9394610
35.

gamma-Linolenic acid-containing diet attenuates bleomycin-induced lung fibrosis in hamsters.

Ziboh VA, Yun M, Hyde DM, Giri SN.

Lipids. 1997 Jul;32(7):759-67.

PMID:
9252965
37.

Pulmonary structural and extracellular matrix alterations in Fischer 344 rats following subchronic phosgene exposure.

Kodavanti UP, Costa DL, Giri SN, Starcher B, Hatch GE.

Fundam Appl Toxicol. 1997 May;37(1):54-63.

PMID:
9193922
38.

Studies on antitussive activity of Drymaria cordata Willd. (Caryophyllaceae).

Mukherjee PK, Saha K, Bhattacharya S, Giri SN, Pal M, Saha BP.

J Ethnopharmacol. 1997 Mar;56(1):77-80.

PMID:
9147257
40.

Differential expression of alpha E beta 7 integrins on bronchoalveolar lavage T lymphocyte subsets: regulation by alpha 4 beta 1-integrin crosslinking and TGF-beta.

Rihs S, Walker C, Virchow JC Jr, Boer C, Kroegel C, Giri SN, Braun RK.

Am J Respir Cell Mol Biol. 1996 Nov;15(5):600-10.

PMID:
8918367
41.
42.

Procollagen gene expression is down-regulated by taurine and niacin at the transcriptional level in the bleomycin hamster model of lung fibrosis.

Gurujeyalakshmi G, Iyer SN, Hollinger MA, Giri SN.

J Pharmacol Exp Ther. 1996 May;277(2):1152-7.

PMID:
8627527
43.

Integrin alpha E beta 7 expression on BAL CD4+, CD8+, and gamma delta T-cells in bleomycin-induced lung fibrosis in mouse.

Braun RK, Sterner-Kock A, Kilshaw PJ, Ferrick DA, Giri SN.

Eur Respir J. 1996 Apr;9(4):673-9.

44.

Antipyretic activity of Nelumbo nucifera rhizome extract.

Mukherjee PK, Das J, Saha K, Giri SN, Pal M, Saha BP.

Indian J Exp Biol. 1996 Mar;34(3):275-6.

PMID:
8781041
47.

Associations among prostaglandin F2alpha, plasma zinc, copper and iron concentrations and fetal loss in cows and mares.

Graham TW, Giri SN, Daels PF, Cullor JS, Keen CL, Thurmond MC, Dellinger JD, Stabenfeldt GH, Osburn BI.

Theriogenology. 1995 Aug;44(3):379-90.

PMID:
16727737
49.

Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters.

Iyer SN, Wild JS, Schiedt MJ, Hyde DM, Margolin SB, Giri SN.

J Lab Clin Med. 1995 Jun;125(6):779-85.

PMID:
7539478
50.

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