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Items: 50

1.

α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis.

Atlante S, Visintin A, Marini E, Savoia M, Dianzani C, Giorgis M, Sürün D, Maione F, Schnütgen F, Farsetti A, Zeiher AM, Bertinaria M, Giraudo E, Spallotta F, Cencioni C, Gaetano C.

Cell Death Dis. 2018 Jul 9;9(7):756. doi: 10.1038/s41419-018-0802-8.

2.

Therapeutic Silencing of miR-214 Inhibits Tumor Progression in Multiple Mouse Models.

Dettori D, Orso F, Penna E, Baruffaldi D, Brundu S, Maione F, Turco E, Giraudo E, Taverna D.

Mol Ther. 2018 Aug 1;26(8):2008-2018. doi: 10.1016/j.ymthe.2018.05.020.

3.

A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.

Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G.

Sci Transl Med. 2018 May 23;10(442). pii: eaah4807. doi: 10.1126/scitranslmed.aah4807. Erratum in: Sci Transl Med. 2018 Jul 25;10(451):.

4.

Inflammatory Cytokines Induce Podoplanin Expression at the Tumor Invasive Front.

Kunita A, Baeriswyl V, Meda C, Cabuy E, Takeshita K, Giraudo E, Wicki A, Fukayama M, Christofori G.

Am J Pathol. 2018 May;188(5):1276-1288. doi: 10.1016/j.ajpath.2018.01.016. Epub 2018 Feb 17.

PMID:
29458011
5.

Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.

Germano G, Lamba S, Rospo G, Barault L, Magrì A, Maione F, Russo M, Crisafulli G, Bartolini A, Lerda G, Siravegna G, Mussolin B, Frapolli R, Montone M, Morano F, de Braud F, Amirouchene-Angelozzi N, Marsoni S, D'Incalci M, Orlandi A, Giraudo E, Sartore-Bianchi A, Siena S, Pietrantonio F, Di Nicolantonio F, Bardelli A.

Nature. 2017 Dec 7;552(7683):116-120. doi: 10.1038/nature24673. Epub 2017 Nov 29.

PMID:
29186113
6.

Multivalent cationic pseudopeptide polyplexes as a tool for cancer therapy.

Diamantopoulou Z, Gilles ME, Sader M, Cossutta M, Vallée B, Houppe C, Habert D, Brissault B, Leroy E, Maione F, Giraudo E, Destouches D, Penelle J, Courty J, Cascone I.

Oncotarget. 2017 Sep 30;8(52):90108-90122. doi: 10.18632/oncotarget.21441. eCollection 2017 Oct 27.

7.

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

Regano D, Visintin A, Clapero F, Bussolino F, Valdembri D, Maione F, Serini G, Giraudo E.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1710-1721. doi: 10.1161/ATVBAHA.117.308226. Epub 2017 Jul 20.

8.

Erratum: Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling.

Avanzato D, Genova T, Fiorio Pla A, Bernardini M, Bianco S, Bussolati B, Mancardi D, Giraudo E, Maione F, Cassoni P, Castellano I, Munaron L.

Sci Rep. 2016 Nov 11;6:35897. doi: 10.1038/srep35897. No abstract available.

9.

Nucleolin Targeting Impairs the Progression of Pancreatic Cancer and Promotes the Normalization of Tumor Vasculature.

Gilles ME, Maione F, Cossutta M, Carpentier G, Caruana L, Di Maria S, Houppe C, Destouches D, Shchors K, Prochasson C, Mongelard F, Lamba S, Bardelli A, Bouvet P, Couvelard A, Courty J, Giraudo E, Cascone I.

Cancer Res. 2016 Dec 15;76(24):7181-7193. Epub 2016 Oct 17.

10.

Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling.

Avanzato D, Genova T, Fiorio Pla A, Bernardini M, Bianco S, Bussolati B, Mancardi D, Giraudo E, Maione F, Cassoni P, Castellano I, Munaron L.

Sci Rep. 2016 Sep 2;6:32602. doi: 10.1038/srep32602. Erratum in: Sci Rep. 2016 Nov 11;6:35897.

11.

Class 3 semaphorins in cardiovascular development.

Valdembri D, Regano D, Maione F, Giraudo E, Serini G.

Cell Adh Migr. 2016 Nov;10(6):641-651. Epub 2016 Jul 20. Review.

12.

Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity.

Leuci V, Maione F, Rotolo R, Giraudo E, Sassi F, Migliardi G, Todorovic M, Gammaitoni L, Mesiano G, Giraudo L, Luraghi P, Leone F, Bussolino F, Grignani G, Aglietta M, Trusolino L, Bertotti A, Sangiolo D.

J Transl Med. 2016 May 5;14(1):119. doi: 10.1186/s12967-016-0872-2.

13.

The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination.

Maione F, Oliaro-Bosso S, Meda C, Di Nicolantonio F, Bussolino F, Balliano G, Viola F, Giraudo E.

Sci Rep. 2015 Mar 12;5:9054. doi: 10.1038/srep09054.

14.

Tumor angiogenesis: methods to analyze tumor vasculature and vessel normalization in mouse models of cancer.

Maione F, Giraudo E.

Methods Mol Biol. 2015;1267:349-65. doi: 10.1007/978-1-4939-2297-0_17.

PMID:
25636478
15.

Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability.

Patella F, Schug ZT, Persi E, Neilson LJ, Erami Z, Avanzato D, Maione F, Hernandez-Fernaud JR, Mackay G, Zheng L, Reid S, Frezza C, Giraudo E, Fiorio Pla A, Anderson K, Ruppin E, Gottlieb E, Zanivan S.

Mol Cell Proteomics. 2015 Mar;14(3):621-34. doi: 10.1074/mcp.M114.045575. Epub 2015 Jan 8.

16.

Semaphorins in cardiovascular medicine.

Corà D, Astanina E, Giraudo E, Bussolino F.

Trends Mol Med. 2014 Oct;20(10):589-98. doi: 10.1016/j.molmed.2014.07.005. Epub 2014 Aug 22. Review.

17.

Peptide-functionalized nanoparticles for selective targeting of pancreatic tumor.

Valetti S, Maione F, Mura S, Stella B, Desmaële D, Noiray M, Vergnaud J, Vauthier C, Cattel L, Giraudo E, Couvreur P.

J Control Release. 2014 Oct 28;192:29-39. doi: 10.1016/j.jconrel.2014.06.039. Epub 2014 Jun 28.

PMID:
24984010
18.

Class 3 semaphorin in angiogenesis and lymphangiogenesis.

Bussolino F, Giraudo E, Serini G.

Chem Immunol Allergy. 2014;99:71-88. doi: 10.1159/000353315. Epub 2013 Oct 17. Review.

PMID:
24217603
19.

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.

Zanivan S, Maione F, Hein MY, Hernández-Fernaud JR, Ostasiewicz P, Giraudo E, Mann M.

Mol Cell Proteomics. 2013 Dec;12(12):3599-611. doi: 10.1074/mcp.M113.031344. Epub 2013 Aug 26.

20.

The role of semaphorins and their receptors in vascular development and cancer.

Gu C, Giraudo E.

Exp Cell Res. 2013 May 15;319(9):1306-16. doi: 10.1016/j.yexcr.2013.02.003. Epub 2013 Feb 17. Review.

21.

Neuropilin-1 identifies a subset of bone marrow Gr1- monocytes that can induce tumor vessel normalization and inhibit tumor growth.

Carrer A, Moimas S, Zacchigna S, Pattarini L, Zentilin L, Ruozi G, Mano M, Sinigaglia M, Maione F, Serini G, Giraudo E, Bussolino F, Giacca M.

Cancer Res. 2012 Dec 15;72(24):6371-81. doi: 10.1158/0008-5472.CAN-12-0762. Epub 2012 Dec 7.

22.

Class 3 semaphorins: physiological vascular normalizing agents for anti-cancer therapy.

Serini G, Bussolino F, Maione F, Giraudo E.

J Intern Med. 2013 Feb;273(2):138-55. doi: 10.1111/joim.12017. Review.

23.

IL-12-dependent innate immunity arrests endothelial cells in G0-G1 phase by a p21(Cip1/Waf1)-mediated mechanism.

Napione L, Strasly M, Meda C, Mitola S, Alvaro M, Doronzo G, Marchiò S, Giraudo E, Primo L, Arese M, Bussolino F.

Angiogenesis. 2012 Dec;15(4):713-25. doi: 10.1007/s10456-012-9286-9. Epub 2012 Jul 15.

PMID:
22797886
24.

Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice.

Maione F, Capano S, Regano D, Zentilin L, Giacca M, Casanovas O, Bussolino F, Serini G, Giraudo E.

J Clin Invest. 2012 May;122(5):1832-48. doi: 10.1172/JCI58976. Epub 2012 Apr 9.

25.

Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages.

Meda C, Molla F, De Pizzol M, Regano D, Maione F, Capano S, Locati M, Mantovani A, Latini R, Bussolino F, Giraudo E.

J Immunol. 2012 Apr 15;188(8):4081-92. doi: 10.4049/jimmunol.1101435. Epub 2012 Mar 21.

26.

Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform.

Casazza A, Kigel B, Maione F, Capparuccia L, Kessler O, Giraudo E, Mazzone M, Neufeld G, Tamagnone L.

EMBO Mol Med. 2012 Mar;4(3):234-50. doi: 10.1002/emmm.201100205. Epub 2012 Jan 13.

27.

A model of vascular tumour growth in mice combining longitudinal tumour size data with histological biomarkers.

Ribba B, Watkin E, Tod M, Girard P, Grenier E, You B, Giraudo E, Freyer G.

Eur J Cancer. 2011 Feb;47(3):479-90. doi: 10.1016/j.ejca.2010.10.003. Epub 2010 Nov 10.

PMID:
21074409
28.

Increased expression of alpha6 integrin in endothelial cells unveils a proangiogenic role for basement membrane.

Primo L, Seano G, Roca C, Maione F, Gagliardi PA, Sessa R, Martinelli M, Giraudo E, di Blasio L, Bussolino F.

Cancer Res. 2010 Jul 15;70(14):5759-69. doi: 10.1158/0008-5472.CAN-10-0507. Epub 2010 Jun 22.

29.

Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models.

Maione F, Molla F, Meda C, Latini R, Zentilin L, Giacca M, Seano G, Serini G, Bussolino F, Giraudo E.

J Clin Invest. 2009 Nov;119(11):3356-72. doi: 10.1172/JCI36308. Epub 2009 Oct 5.

30.

Regulation of HMGCoA reductase activity by policosanol and octacosadienol, a new synthetic analogue of octacosanol.

Oliaro-Bosso S, Calcio Gaudino E, Mantegna S, Giraudo E, Meda C, Viola F, Cravotto G.

Lipids. 2009 Oct;44(10):907-16. doi: 10.1007/s11745-009-3338-y. Epub 2009 Sep 11.

31.

Semaphorins and tumor angiogenesis.

Serini G, Maione F, Giraudo E, Bussolino F.

Angiogenesis. 2009;12(2):187-93. doi: 10.1007/s10456-009-9138-4. Epub 2009 Mar 6. Review. Erratum in: Angiogenesis. 2009;12(2):195. Giraudo, Enrico [added].

PMID:
19266292
32.

AP-2alpha and AP-2gamma regulate tumor progression via specific genetic programs.

Orso F, Penna E, Cimino D, Astanina E, Maione F, Valdembri D, Giraudo E, Serini G, Sismondi P, De Bortoli M, Taverna D.

FASEB J. 2008 Aug;22(8):2702-14. doi: 10.1096/fj.08-106492. Epub 2008 Apr 28.

PMID:
18443366
33.

Lymphatic zip codes in premalignant lesions and tumors.

Zhang L, Giraudo E, Hoffman JA, Hanahan D, Ruoslahti E.

Cancer Res. 2006 Jun 1;66(11):5696-706. Erratum in: Cancer Res. 2006 Jul 1;66(13):6894.

34.

CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer.

Daniel D, Chiu C, Giraudo E, Inoue M, Mizzen LA, Chu NR, Hanahan D.

Cancer Res. 2005 Mar 1;65(5):2018-25.

35.
36.

Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis.

Joyce JA, Baruch A, Chehade K, Meyer-Morse N, Giraudo E, Tsai FY, Greenbaum DC, Hager JH, Bogyo M, Hanahan D.

Cancer Cell. 2004 May;5(5):443-53.

37.

Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma.

Hoffman JA, Giraudo E, Singh M, Zhang L, Inoue M, Porkka K, Hanahan D, Ruoslahti E.

Cancer Cell. 2003 Nov;4(5):383-91.

38.

Temporal and spatial modulation of Rho GTPases during in vitro formation of capillary vascular network. Adherens junctions and myosin light chain as targets of Rac1 and RhoA.

Cascone I, Giraudo E, Caccavari F, Napione L, Bertotti E, Collard JG, Serini G, Bussolino F.

J Biol Chem. 2003 Dec 12;278(50):50702-13. Epub 2003 Sep 12. Erratum in: J Biol Chem. 2004 Aug 27;279(35):37208-9.

39.

Tumor-host interaction mediates the regression of BK virus-induced vascular tumors in mice: involvement of transforming growth factor-beta1.

Corallini A, Possati L, Trabanelli C, Giraudo E, Rocchetti R, Talevi S, Caputo A, Bussolino F, Barbanti-Brodano G.

Carcinogenesis. 2003 Sep;24(9):1435-44. Epub 2003 Jul 4.

PMID:
12844479
40.

Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1.

Cascone I, Audero E, Giraudo E, Napione L, Maniero F, Philips MR, Collard JG, Serini G, Bussolino F.

Blood. 2003 Oct 1;102(7):2482-90. Epub 2003 Jun 19.

PMID:
12816861
41.

Modeling the early stages of vascular network assembly.

Serini G, Ambrosi D, Giraudo E, Gamba A, Preziosi L, Bussolino F.

EMBO J. 2003 Apr 15;22(8):1771-9.

42.

Percolation, morphogenesis, and burgers dynamics in blood vessels formation.

Gamba A, Ambrosi D, Coniglio A, de Candia A, Di Talia S, Giraudo E, Serini G, Preziosi L, Bussolino F.

Phys Rev Lett. 2003 Mar 21;90(11):118101. Epub 2003 Mar 17.

PMID:
12688968
43.

Tat-induced platelet-activating factor synthesis contributes to the angiogenic effect of HIV-1 Tat.

Del Sorbo L, Arese M, Giraudo E, Tizzani M, Biancone L, Bussolino F, Camussi G.

Eur J Immunol. 2001 Feb;31(2):376-83.

44.

Src-mediated activation of alpha-diacylglycerol kinase is required for hepatocyte growth factor-induced cell motility.

Cutrupi S, Baldanzi G, Gramaglia D, Maffè A, Schaap D, Giraudo E, van Blitterswijk W, Bussolino F, Comoglio PM, Graziani A.

EMBO J. 2000 Sep 1;19(17):4614-22.

45.

Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.

Giraudo E, Primo L, Audero E, Gerber HP, Koolwijk P, Soker S, Klagsbrun M, Ferrara N, Bussolino F.

J Biol Chem. 1998 Aug 21;273(34):22128-35.

46.

The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells.

Albini A, Soldi R, Giunciuglio D, Giraudo E, Benelli R, Primo L, Noonan D, Salio M, Camussi G, Rockl W, Bussolino F.

Nat Med. 1996 Dec;2(12):1371-5.

PMID:
8946838
47.

IL-6 is an in vitro and in vivo autocrine growth factor for middle T antigen-transformed endothelial cells.

Giraudo E, Arese M, Toniatti C, Strasly M, Primo L, Mantovani A, Ciliberto G, Bussolini F.

J Immunol. 1996 Sep 15;157(6):2618-23.

PMID:
8805665
48.

In vivo activation of met tyrosine kinase by heterodimeric hepatocyte growth factor molecule promotes angiogenesis.

Silvagno F, Follenzi A, Arese M, Prat M, Giraudo E, Gaudino G, Camussi G, Comoglio PM, Bussolino F.

Arterioscler Thromb Vasc Biol. 1995 Nov;15(11):1857-65.

PMID:
7583565
49.

A brain phantom for studying contrast recovery in emission computerized tomography.

Pupi A, De Cristofaro MT, Formiconi AR, Passeri A, Speranzi A, Giraudo E, Meldolesi U.

Eur J Nucl Med. 1990;17(1-2):15-20.

PMID:
2083539
50.

[Recent trends in the treatment of inflammatory diseases of the female genitalia].

Macchioni B, Poggio A, Cutini V, Giraudo E.

Arch Sci Med (Torino). 1968 Aug;125(8):347-59. Italian. No abstract available.

PMID:
5733618

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