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Items: 1 to 50 of 59

1.

Pharmacovigilance in ophthalmology in Switzerland: an analysis of the most frequently reported ocular adverse drug reactions within the last 25 years.

Karrer JE, Giovannoni L, Kullak-Ublick GA, Weiler S.

Swiss Med Wkly. 2019 Jun 30;149:w20085. doi: 10.4414/smw.2019.20085. eCollection 2019 Jun 17.

2.

Carbon stocks of mangroves and salt marshes of the Amazon region, Brazil.

Kauffman JB, Bernardino AF, Ferreira TO, Giovannoni LR, de O Gomes LE, Romero DJ, Jimenez LCZ, Ruiz F.

Biol Lett. 2018 Sep;14(9). pii: 20180208. doi: 10.1098/rsbl.2018.0208.

3.

Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.

Petrenko V, Saini C, Giovannoni L, Gobet C, Sage D, Unser M, Heddad Masson M, Gu G, Bosco D, Gachon F, Philippe J, Dibner C.

Genes Dev. 2017 Feb 15;31(4):383-398. doi: 10.1101/gad.290379.116. Epub 2017 Mar 8.

4.

Nurses as seen by patients: a phenomenological study.

Nannelli T, Calamassi D, Ciucciarelli A, Comerci S, Fadanelli M, Fanfani C, Favero G, Galli R, Giovannoni L, Innocenti L, Orsi M, Brunetti G.

Prof Inferm. 2015 Jul-Sep;68(3):175-85. doi: 10.7429/pi.2015.6804175.

PMID:
26749550
5.

A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells.

Saini C, Petrenko V, Pulimeno P, Giovannoni L, Berney T, Hebrok M, Howald C, Dermitzakis ET, Dibner C.

Diabetes Obes Metab. 2016 Apr;18(4):355-65. doi: 10.1111/dom.12616. Epub 2016 Jan 22.

PMID:
26662378
6.

Open visiting policies in Intensive Care Units may not affect consent to organ donation.

Bambi S, Bombardi M, Bonizzoli M, Migliaccio ML, Giovannoni L, Minardi A, Peris A.

Br J Anaesth. 2015 Jul;115(1):142-3. doi: 10.1093/bja/aev179. No abstract available.

7.

Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study.

Danielli R, Patuzzo R, Di Giacomo AM, Gallino G, Maurichi A, Di Florio A, Cutaia O, Lazzeri A, Fazio C, Miracco C, Giovannoni L, Elia G, Neri D, Maio M, Santinami M.

Cancer Immunol Immunother. 2015 Aug;64(8):999-1009. doi: 10.1007/s00262-015-1704-6. Epub 2015 May 14.

PMID:
25971540
8.

Potentiating the activity of rituximab against mantle cell lymphoma in mice by targeting interleukin-2 to the neovasculature.

Börschel N, Schwöppe C, Zerbst C, Angenendt L, Kessler T, Klapper W, Giovannoni L, Elia G, Neri D, Berdel WE, Mesters RM, Schliemann C.

Leuk Res. 2015 Jul;39(7):739-48. doi: 10.1016/j.leukres.2015.04.005. Epub 2015 Apr 17.

PMID:
25934049
9.

Targeted ED-B fibronectin SPECT in vivo imaging in experimental atherosclerosis.

Dietrich T, Berndorff D, Heinrich T, Hucko T, Stepina E, Hauff P, Dinkelborg LM, Atrott K, Giovannoni L, Neri D, Fleck E, Graf K, Menssen HD.

Q J Nucl Med Mol Imaging. 2015 Jun;59(2):228-37.

PMID:
25864530
10.

Targeting interleukin-2 to the bone marrow stroma for therapy of acute myeloid leukemia relapsing after allogeneic hematopoietic stem cell transplantation.

Schliemann C, Gutbrodt KL, Kerkhoff A, Pohlen M, Wiebe S, Silling G, Angenendt L, Kessler T, Mesters RM, Giovannoni L, Schäfers M, Altvater B, Rossig C, Grünewald I, Wardelmann E, Köhler G, Neri D, Stelljes M, Berdel WE.

Cancer Immunol Res. 2015 May;3(5):547-56. doi: 10.1158/2326-6066.CIR-14-0179. Epub 2015 Feb 11.

11.

The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic breast cancer.

Catania C, Maur M, Berardi R, Rocca A, Giacomo AM, Spitaleri G, Masini C, Pierantoni C, González-Iglesias R, Zigon G, Tasciotti A, Giovannoni L, Lovato V, Elia G, Menssen HD, Neri D, Cascinu S, Conte PF, Braud Fd.

Cell Adh Migr. 2015;9(1-2):14-21. doi: 10.4161/19336918.2014.983785.

12.

A phase IB clinical trial with Dekavil (F8-IL10), an immunoregulatory 'armed antibody' for the treatment of rheumatoid arthritis, used in combination wiIh methotrexate.

Galeazzi M, Bazzichi L, Sebastiani GD, Neri D, Garcia E, Ravenni N, Giovannoni L, Wilton J, Bardelli M, Baldi C, Selvi E, Iuliano A, Minisola G, Caporali R, Prisco E, Bombardieri S.

Isr Med Assoc J. 2014 Oct;16(10):666. No abstract available.

13.

Enhancement of islet engraftment and achievement of long-term islet allograft survival by Toll-like receptor 4 blockade.

Giovannoni L, Muller YD, Lacotte S, Parnaud G, Borot S, Meier RP, Lavallard V, Bédat B, Toso C, Daubeuf B, Elson G, Shang L, Morel P, Kosco-Vilbois M, Bosco D, Berney T.

Transplantation. 2015 Jan;99(1):29-35. doi: 10.1097/TP.0000000000000468.

PMID:
25340601
14.

Armed antibodies for cancer treatment: a promising tool in a changing era.

Danielli R, Patuzzo R, Ruffini PA, Maurichi A, Giovannoni L, Elia G, Neri D, Santinami M.

Cancer Immunol Immunother. 2015 Jan;64(1):113-21. doi: 10.1007/s00262-014-1621-0. Epub 2014 Oct 15. Review.

PMID:
25314912
15.

Intralesional treatment of stage III metastatic melanoma patients with L19-IL2 results in sustained clinical and systemic immunologic responses.

Weide B, Eigentler TK, Pflugfelder A, Zelba H, Martens A, Pawelec G, Giovannoni L, Ruffini PA, Elia G, Neri D, Gutzmer R, Becker JC, Garbe C.

Cancer Immunol Res. 2014 Jul;2(7):668-78. doi: 10.1158/2326-6066.CIR-13-0206. Epub 2014 Apr 4.

16.

Radretumab radioimmunotherapy in patients with brain metastasis: a 124I-L19SIP dosimetric PET study.

Poli GL, Bianchi C, Virotta G, Bettini A, Moretti R, Trachsel E, Elia G, Giovannoni L, Neri D, Bruno A.

Cancer Immunol Res. 2013 Aug;1(2):134-43. doi: 10.1158/2326-6066.CIR-13-0007. Epub 2013 May 20.

17.

Survival of free and encapsulated human and rat islet xenografts transplanted into the mouse bone marrow.

Meier RP, Seebach JD, Morel P, Mahou R, Borot S, Giovannoni L, Parnaud G, Montanari E, Bosco D, Wandrey C, Berney T, Bühler LH, Muller YD.

PLoS One. 2014 Mar 13;9(3):e91268. doi: 10.1371/journal.pone.0091268. eCollection 2014.

18.

Radioimmunotherapy with Tenarad, a 131I-labelled antibody fragment targeting the extra-domain A1 of tenascin-C, in patients with refractory Hodgkin's lymphoma.

Aloj L, D'Ambrosio L, Aurilio M, Morisco A, Frigeri F, Caraco' C, Di Gennaro F, Capobianco G, Giovannoni L, Menssen HD, Neri D, Pinto A, Lastoria S.

Eur J Nucl Med Mol Imaging. 2014 May;41(5):867-77. doi: 10.1007/s00259-013-2658-6. Epub 2014 Jan 17.

PMID:
24435772
19.

Abundant in vitro expression of the oncofetal ED-B-containing fibronectin translates into selective pharmacodelivery of (131)I-L19SIP in a prostate cancer patient.

Locher R, Erba PA, Hirsch B, Bombardieri E, Giovannoni L, Neri D, Dürkop H, Menssen HD.

J Cancer Res Clin Oncol. 2014 Jan;140(1):35-43. doi: 10.1007/s00432-013-1538-6. Epub 2013 Oct 17.

PMID:
24132461
20.

Endocrine secretory reserve and proinsulin processing in recipients of islet of langerhans versus whole pancreas transplants.

Elkhafif NM, Borot S, Morel P, Demuylder-Mischler S, Giovannoni L, Toso C, Bosco D, Berney T.

Diabetes Care. 2013 Nov;36(11):3726-31. doi: 10.2337/dc12-2710. Epub 2013 Sep 16.

21.

Antibody-based delivery of interleukin-2 to neovasculature has potent activity against acute myeloid leukemia.

Gutbrodt KL, Schliemann C, Giovannoni L, Frey K, Pabst T, Klapper W, Berdel WE, Neri D.

Sci Transl Med. 2013 Sep 4;5(201):201ra118. doi: 10.1126/scitranslmed.3006221.

22.

Quantification of islet loss and graft functionality during immune rejection by 3-tesla MRI in a rat model.

Borot S, Crowe LA, Parnaud G, Ris F, Meier R, Giovannoni L, Müller YD, Lacotte S, Morel P, Toso C, Bosco D, Vallee JP, Berney T.

Transplantation. 2013 Sep 15;96(5):438-44. doi: 10.1097/TP.0b013e31829b080f.

PMID:
23902991
23.

The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity.

Hemmerle T, Probst P, Giovannoni L, Green AJ, Meyer T, Neri D.

Br J Cancer. 2013 Sep 3;109(5):1206-13. doi: 10.1038/bjc.2013.421. Epub 2013 Jul 25.

24.

Phase 0 microdosing PET study using the human mini antibody F16SIP in head and neck cancer patients.

Heuveling DA, de Bree R, Vugts DJ, Huisman MC, Giovannoni L, Hoekstra OS, Leemans CR, Neri D, van Dongen GA.

J Nucl Med. 2013 Mar;54(3):397-401. doi: 10.2967/jnumed.112.111310. Epub 2013 Jan 18.

25.

Autonomous and self-sustained circadian oscillators displayed in human islet cells.

Pulimeno P, Mannic T, Sage D, Giovannoni L, Salmon P, Lemeille S, Giry-Laterriere M, Unser M, Bosco D, Bauer C, Morf J, Halban P, Philippe J, Dibner C.

Diabetologia. 2013 Mar;56(3):497-507. doi: 10.1007/s00125-012-2779-7. Epub 2012 Dec 15.

26.

Phase I/II study of the tumour-targeting human monoclonal antibody-cytokine fusion protein L19-TNF in patients with advanced solid tumours.

Spitaleri G, Berardi R, Pierantoni C, De Pas T, Noberasco C, Libbra C, González-Iglesias R, Giovannoni L, Tasciotti A, Neri D, Menssen HD, de Braud F.

J Cancer Res Clin Oncol. 2013 Mar;139(3):447-55. doi: 10.1007/s00432-012-1327-7. Epub 2012 Nov 17.

PMID:
23160853
27.

Isolated limb perfusion with the tumor-targeting human monoclonal antibody-cytokine fusion protein L19-TNF plus melphalan and mild hyperthermia in patients with locally advanced extremity melanoma.

Papadia F, Basso V, Patuzzo R, Maurichi A, Di Florio A, Zardi L, Ventura E, González-Iglesias R, Lovato V, Giovannoni L, Tasciotti A, Neri D, Santinami M, Menssen HD, De Cian F.

J Surg Oncol. 2013 Feb;107(2):173-9. doi: 10.1002/jso.23168. Epub 2012 Jun 4.

PMID:
22674435
28.

Radioimmunotherapy with radretumab in patients with relapsed hematologic malignancies.

Erba PA, Sollini M, Orciuolo E, Traino C, Petrini M, Paganelli G, Bombardieri E, Grana C, Giovannoni L, Neri D, Menssen HD, Mariani G.

J Nucl Med. 2012 Jun;53(6):922-7. doi: 10.2967/jnumed.111.101006. Epub 2012 May 10.

29.

A dose-escalation and signal-generating study of the immunocytokine L19-IL2 in combination with dacarbazine for the therapy of patients with metastatic melanoma.

Eigentler TK, Weide B, de Braud F, Spitaleri G, Romanini A, Pflugfelder A, González-Iglesias R, Tasciotti A, Giovannoni L, Schwager K, Lovato V, Kaspar M, Trachsel E, Menssen HD, Neri D, Garbe C.

Clin Cancer Res. 2011 Dec 15;17(24):7732-42. doi: 10.1158/1078-0432.CCR-11-1203. Epub 2011 Oct 25.

30.

Cadherin engagement protects human β-cells from apoptosis.

Parnaud G, Gonelle-Gispert C, Morel P, Giovannoni L, Muller YD, Meier R, Borot S, Berney T, Bosco D.

Endocrinology. 2011 Dec;152(12):4601-9. doi: 10.1210/en.2011-1286. Epub 2011 Oct 11.

PMID:
21990317
31.

Impact of the number of infusions on 2-year results of islet-after-kidney transplantation in the GRAGIL network.

Borot S, Niclauss N, Wojtusciszyn A, Brault C, Demuylder-Mischler S, Müller Y, Giovannoni L, Parnaud G, Meier R, Badet L, Bayle F, Frimat L, Kessler L, Morelon E, Penfornis A, Thivolet C, Toso C, Morel P, Bosco D, Colin C, Benhamou PY, Berney T; GRAGIL Network.

Transplantation. 2011 Nov 15;92(9):1031-8. doi: 10.1097/TP.0b013e318230c236.

PMID:
21926944
32.

Immunosuppressive effects of streptozotocin-induced diabetes result in absolute lymphopenia and a relative increase of T regulatory cells.

Muller YD, Golshayan D, Ehirchiou D, Wyss JC, Giovannoni L, Meier R, Serre-Beinier V, Puga Yung G, Morel P, Bühler LH, Seebach JD.

Diabetes. 2011 Sep;60(9):2331-40. doi: 10.2337/db11-0159. Epub 2011 Jul 13.

33.

Influence of donor age on islet isolation and transplantation outcome.

Niclauss N, Bosco D, Morel P, Demuylder-Mischler S, Brault C, Milliat-Guittard L, Colin C, Parnaud G, Muller YD, Giovannoni L, Meier R, Toso C, Badet L, Benhamou PY, Berney T.

Transplantation. 2011 Feb 15;91(3):360-6.

PMID:
21344706
34.

Rapamycin impairs proliferation of transplanted islet β cells.

Niclauss N, Bosco D, Morel P, Giovannoni L, Berney T, Parnaud G.

Transplantation. 2011 Apr 15;91(7):714-22. doi: 10.1097/TP.0b013e31820c10c8.

PMID:
21297554
35.

Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism.

Vetterli L, Brun T, Giovannoni L, Bosco D, Maechler P.

J Biol Chem. 2011 Feb 25;286(8):6049-60. doi: 10.1074/jbc.M110.176842. Epub 2010 Dec 16.

36.

The tumour-targeting human L19-IL2 immunocytokine: preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma.

Johannsen M, Spitaleri G, Curigliano G, Roigas J, Weikert S, Kempkensteffen C, Roemer A, Kloeters C, Rogalla P, Pecher G, Miller K, Berndt A, Kosmehl H, Trachsel E, Kaspar M, Lovato V, González-Iglesias R, Giovannoni L, Menssen HD, Neri D, de Braud F.

Eur J Cancer. 2010 Nov;46(16):2926-35. doi: 10.1016/j.ejca.2010.07.033. Epub 2010 Aug 24.

PMID:
20797845
37.

Assessment of human islet labeling with clinical grade iron nanoparticles prior to transplantation for graft monitoring by MRI.

Ris F, Lepetit-Coiffe M, Meda P, Crowe LA, Toso C, Armanet M, Niclauss N, Parnaud G, Giovannoni L, Bosco D, Morel P, Vallee JP, Berney T.

Cell Transplant. 2010;19(12):1573-85. doi: 10.3727/096368910X515863. Epub 2010 Aug 17.

PMID:
20719068
38.

Expression, engineering and characterization of the tumor-targeting heterodimeric immunocytokine F8-IL12.

Sommavilla R, Pasche N, Trachsel E, Giovannoni L, Roesli C, Villa A, Neri D, Kaspar M.

Protein Eng Des Sel. 2010 Aug;23(8):653-61. doi: 10.1093/protein/gzq038. Epub 2010 Jun 15.

PMID:
20551083
39.

Unique arrangement of alpha- and beta-cells in human islets of Langerhans.

Bosco D, Armanet M, Morel P, Niclauss N, Sgroi A, Muller YD, Giovannoni L, Parnaud G, Berney T.

Diabetes. 2010 May;59(5):1202-10. doi: 10.2337/db09-1177. Epub 2010 Feb 25.

40.

Expression of the oncofetal ED-B-containing fibronectin isoform in hematologic tumors enables ED-B-targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients.

Sauer S, Erba PA, Petrini M, Menrad A, Giovannoni L, Grana C, Hirsch B, Zardi L, Paganelli G, Mariani G, Neri D, Dürkop H, Menssen HD.

Blood. 2009 Mar 5;113(10):2265-74. doi: 10.1182/blood-2008-06-160416. Epub 2009 Jan 8.

41.

TNFA locus is associated with beta degrees 39 thalassemia in Corsica and Sardinia.

Giovannoni L.

Eur Cytokine Netw. 2008 Dec;19(4):196-203. doi: 10.1684/ecn.2008.0136.

42.

A general method for the selection of high-level scFv and IgG antibody expression by stably transfected mammalian cells.

Zuberbühler K, Palumbo A, Bacci C, Giovannoni L, Sommavilla R, Kaspar M, Trachsel E, Neri D.

Protein Eng Des Sel. 2009 Mar;22(3):169-74. doi: 10.1093/protein/gzn068. Epub 2008 Nov 20.

PMID:
19022802
43.

Antibody-mediated delivery of interleukin-2 to the stroma of breast cancer strongly enhances the potency of chemotherapy.

Mårlind J, Kaspar M, Trachsel E, Sommavilla R, Hindle S, Bacci C, Giovannoni L, Neri D.

Clin Cancer Res. 2008 Oct 15;14(20):6515-24. doi: 10.1158/1078-0432.CCR-07-5041.

44.

Frequencies of promoter pentanucleotide (TTTTA)n of CYP11A gene in European and North African populations.

Piras I, Falchi A, Moral P, Melis A, Giovannoni L, Paoli G, Calò C, Vona G, Varesi L.

Genet Test. 2008 Mar;12(1):93-6. doi: 10.1089/gte.2007.0060.

PMID:
18307388
45.

Population genetic data on four STR loci, PAI (CA)n, GpIIIa (CT)n, PLAT (TG)14 (CA)12, and NOS2A (CCTTT)n, in Mediterranean populations.

Falchi A, Piras IS, Giovannoni L, Moral P, Vona G, Varesi L.

Leg Med (Tokyo). 2007 Jul;9(4):218-20. Epub 2007 Feb 22.

PMID:
17320454
46.

Cholesteryl ester transfer protein gene polymorphisms are associated with coronary artery disease in Corsican population (France).

Falchi A, Piras IS, Vona G, Amoros JP, Calo' CM, Giovannoni L, Varesi L.

Exp Mol Pathol. 2007 Aug;83(1):25-9. Epub 2006 Dec 30.

PMID:
17275808
47.

Genetic history of some western Mediterranean human isolates through mtDNA HVR1 polymorphisms.

Falchi A, Giovannoni L, Calo CM, Piras IS, Moral P, Paoli G, Vona G, Varesi L.

J Hum Genet. 2006;51(1):9-14. Epub 2005 Nov 24. Review.

PMID:
16307178
48.

Prevalence of genetic risk factors for coronary artery disease in Corsica island (France).

Falchi A, Giovannoni L, Piras IS, Calo CM, Moral P, Vona G, Varesi L.

Exp Mol Pathol. 2005 Dec;79(3):210-3. Epub 2005 Oct 24.

PMID:
16248996
49.

beta-globin gene cluster haplotypes associated with beta-thalassemia on Corsica island.

Falchi A, Giovannoni L, Vacca L, Latini V, Vona G, Varesi L.

Am J Hematol. 2005 Jan;78(1):27-32.

50.

Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer.

Santimaria M, Moscatelli G, Viale GL, Giovannoni L, Neri G, Viti F, Leprini A, Borsi L, Castellani P, Zardi L, Neri D, Riva P.

Clin Cancer Res. 2003 Feb;9(2):571-9.

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