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Items: 1 to 50 of 193

1.

Dietary habits affect fatty acid composition of visceral adipose tissue in subjects with colorectal cancer or obesity.

Scazzocchio B, Varì R, Silenzi A, Giammarioli S, Masotti A, Baldassarre A, Santangelo C, D'Archivio M, Giovannini C, Del Cornò M, Conti L, Gessani S, Masella R.

Eur J Nutr. 2019 May 22. doi: 10.1007/s00394-019-02003-7. [Epub ahead of print]

PMID:
31119400
2.

Brivanib in combination with Notch3 silencing shows potent activity in tumour models.

Giovannini C, Salzano AM, Baglioni M, Vitale M, Scaloni A, Zambrano N, Giannone FA, Vasuri F, D'Errico A, Svegliati Baroni G, Bolondi L, Gramantieri L.

Br J Cancer. 2019 Mar;120(6):601-611. doi: 10.1038/s41416-018-0375-4. Epub 2019 Feb 15.

PMID:
30765875
3.

LncRNAs as novel players in hepatocellular carcinoma recurrence.

Gramantieri L, Baglioni M, Fornari F, Laginestra MA, Ferracin M, Indio V, Ravaioli M, Cescon M, De Pace V, Leoni S, Coadă CA, Negrini M, Bolondi L, Giovannini C.

Oncotarget. 2018 Oct 12;9(80):35085-35099. doi: 10.18632/oncotarget.26202. eCollection 2018 Oct 12.

4.

Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease.

Chioua M, Buzzi E, Moraleda I, Iriepa I, Maj M, Wnorowski A, Giovannini C, Tramarin A, Portali F, Ismaili L, López-Alvarado P, Bolognesi ML, Jóźwiak K, Menéndez JC, Marco-Contelles J, Bartolini M.

Eur J Med Chem. 2018 Jul 15;155:839-846. doi: 10.1016/j.ejmech.2018.06.044. Epub 2018 Jun 19.

PMID:
29958119
5.

Effect of protocatechuic acid on insulin responsiveness and inflammation in visceral adipose tissue from obese individuals: possible role for PTP1B.

Ormazabal P, Scazzocchio B, Varì R, Santangelo C, D'Archivio M, Silecchia G, Iacovelli A, Giovannini C, Masella R.

Int J Obes (Lond). 2018 Dec;42(12):2012-2021. doi: 10.1038/s41366-018-0075-4. Epub 2018 May 16.

PMID:
29769704
6.

The epigenetically regulated miR-494 associates with stem-cell phenotype and induces sorafenib resistance in hepatocellular carcinoma.

Pollutri D, Patrizi C, Marinelli S, Giovannini C, Trombetta E, Giannone FA, Baldassarre M, Quarta S, Vandewynckel YP, Vandierendonck A, Van Vlierberghe H, Porretti L, Negrini M, Bolondi L, Gramantieri L, Fornari F.

Cell Death Dis. 2018 Jan 5;9(1):4. doi: 10.1038/s41419-017-0076-6.

7.

Corrigendum: Vidatox 30 CH has tumor activating effect in hepatocellular carcinoma.

Giovannini C, Baglioni M, Toaldo MB, Cescon M, Bolondi L, Gramantieri L.

Sci Rep. 2017 Dec 22;7:46920. doi: 10.1038/srep46920.

8.

MiR-199-3p replacement affects E-cadherin expression through Notch1 targeting in hepatocellular carcinoma.

Giovannini C, Fornari F, Dallo R, Gagliardi M, Nipoti E, Vasuri F, Coadă CA, Ravaioli M, Bolondi L, Gramantieri L.

Acta Histochem. 2018 Feb;120(2):95-102. doi: 10.1016/j.acthis.2017.12.004. Epub 2017 Dec 15.

PMID:
29249451
9.

Recent Evidence on the Role of Dietary PUFAs in Cancer Development and Prevention.

D'Archivio M, Scazzocchio B, Vari R, Santangelo C, Giovannini C, Masella R.

Curr Med Chem. 2018;25(16):1818-1836. doi: 10.2174/0929867325666171204160231. Review.

PMID:
29210633
10.

Anti-inflammatory Activity of Extra Virgin Olive Oil Polyphenols: Which Role in the Prevention and Treatment of Immune-Mediated Inflammatory Diseases?

Santangelo C, Vari R, Scazzocchio B, De Sanctis P, Giovannini C, D'Archivio M, Masella R.

Endocr Metab Immune Disord Drug Targets. 2018;18(1):36-50. doi: 10.2174/1871530317666171114114321. Review.

PMID:
29141574
11.

Vidatox 30 CH has tumor activating effect in hepatocellular carcinoma.

Giovannini C, Baglioni M, Baron Toaldo M, Cescon M, Bolondi L, Gramantieri L.

Sci Rep. 2017 Mar 21;7:44685. doi: 10.1038/srep44685. Erratum in: Sci Rep. 2017 Dec 22;7:46920.

12.

In Hepatocellular Carcinoma miR-221 Modulates Sorafenib Resistance through Inhibition of Caspase-3-Mediated Apoptosis.

Fornari F, Pollutri D, Patrizi C, La Bella T, Marinelli S, Casadei Gardini A, Marisi G, Baron Toaldo M, Baglioni M, Salvatore V, Callegari E, Baldassarre M, Galassi M, Giovannini C, Cescon M, Ravaioli M, Negrini M, Bolondi L, Gramantieri L.

Clin Cancer Res. 2017 Jul 15;23(14):3953-3965. doi: 10.1158/1078-0432.CCR-16-1464. Epub 2017 Jan 17.

13.

Targeting Notch3 in Hepatocellular Carcinoma: Molecular Mechanisms and Therapeutic Perspectives.

Giovannini C, Bolondi L, Gramantieri L.

Int J Mol Sci. 2016 Dec 28;18(1). pii: E56. doi: 10.3390/ijms18010056. Review.

14.

Molecular and proteomic insight into Notch1 characterization in hepatocellular carcinoma.

Giovannini C, Minguzzi M, Genovese F, Baglioni M, Gualandi A, Ravaioli M, Milazzo M, Tavolari S, Bolondi L, Gramantieri L.

Oncotarget. 2016 Jun 28;7(26):39609-39626. doi: 10.18632/oncotarget.9203.

15.

Consumption of extra-virgin olive oil rich in phenolic compounds improves metabolic control in patients with type 2 diabetes mellitus: a possible involvement of reduced levels of circulating visfatin.

Santangelo C, Filesi C, Varì R, Scazzocchio B, Filardi T, Fogliano V, D'Archivio M, Giovannini C, Lenzi A, Morano S, Masella R.

J Endocrinol Invest. 2016 Nov;39(11):1295-1301. Epub 2016 Jun 25.

PMID:
27344308
16.

Gender-related differences in lifestyle may affect health status.

Varì R, Scazzocchio B, D'Amore A, Giovannini C, Gessani S, Masella R.

Ann Ist Super Sanita. 2016 Apr-Jun;52(2):158-66. doi: 10.4415/ANN_16_02_06. Review.

17.

Different repair kinetic of DSBs induced by mitomycin C in peripheral lymphocytes of obese and normal weight adolescents.

Azzarà A, Pirillo C, Giovannini C, Federico G, Scarpato R.

Mutat Res. 2016 Jul;789:9-14. doi: 10.1016/j.mrfmmm.2016.05.001. Epub 2016 May 3.

PMID:
27174706
18.

Vincristine-induced bystander effect in human lymphocytes.

Testi S, Azzarà A, Giovannini C, Lombardi S, Piaggi S, Facioni MS, Scarpato R.

Mutat Res. 2016 Jul;789:39-47. doi: 10.1016/j.mrfmmm.2016.03.001. Epub 2016 Mar 25.

PMID:
27050754
19.

Laparoscopic resection of splenic flexure tumors.

Carlini M, Spoletini D, Castaldi F, Giovannini C, Passaro U.

Updates Surg. 2016 Mar;68(1):77-83. doi: 10.1007/s13304-016-0357-0. Epub 2016 Apr 4.

PMID:
27040272
20.

Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages.

Varì R, Scazzocchio B, Santangelo C, Filesi C, Galvano F, D'Archivio M, Masella R, Giovannini C.

Oxid Med Cell Longev. 2015;2015:351827. doi: 10.1155/2015/351827. Epub 2015 Jun 9.

21.

Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity.

Scazzocchio B, Varì R, Filesi C, Del Gaudio I, D'Archivio M, Santangelo C, Iacovelli A, Galvano F, Pluchinotta FR, Giovannini C, Masella R.

Mol Nutr Food Res. 2015 Aug;59(8):1472-81. doi: 10.1002/mnfr.201400816. Epub 2015 May 29.

PMID:
25944785
22.

High levels of γ-H2AX foci and cell membrane oxidation in adolescents with type 1 diabetes.

Giovannini C, Piaggi S, Federico G, Scarpato R.

Mutat Res. 2014 Dec;770:128-35. doi: 10.1016/j.mrfmmm.2014.08.005. Epub 2014 Aug 27.

PMID:
25771879
23.

Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma.

Giovannini C, Minguzzi M, Baglioni M, Fornari F, Giannone F, Ravaioli M, Cescon M, Chieco P, Bolondi L, Gramantieri L.

Oncotarget. 2014 Nov 15;5(21):10607-20.

24.

ω3-PUFAs exert anti-inflammatory activity in visceral adipocytes from colorectal cancer patients.

D'Archivio M, Scazzocchio B, Giammarioli S, Fiani ML, Varì R, Santangelo C, Veneziani A, Iacovelli A, Giovannini C, Gessani S, Masella R.

PLoS One. 2013 Oct 7;8(10):e77432. doi: 10.1371/journal.pone.0077432. eCollection 2013.

25.

Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma.

Giovannini C, Baglioni M, Baron Toaldo M, Ventrucci C, D'Adamo S, Cipone M, Chieco P, Gramantieri L, Bolondi L.

Oncotarget. 2013 Oct;4(10):1618-31.

26.

Kinetics of nuclear phosphorylation (γ-H2AX) in human lymphocytes treated in vitro with UVB, bleomycin and mitomycin C.

Scarpato R, Castagna S, Aliotta R, Azzarà A, Ghetti F, Filomeni E, Giovannini C, Pirillo C, Testi S, Lombardi S, Tomei A.

Mutagenesis. 2013 Jul;28(4):465-73. doi: 10.1093/mutage/get024. Epub 2013 May 21.

PMID:
23696313
27.

Blood microRNA changes in depressed patients during antidepressant treatment.

Bocchio-Chiavetto L, Maffioletti E, Bettinsoli P, Giovannini C, Bignotti S, Tardito D, Corrada D, Milanesi L, Gennarelli M.

Eur Neuropsychopharmacol. 2013 Jul;23(7):602-11. doi: 10.1016/j.euroneuro.2012.06.013. Epub 2012 Aug 25.

PMID:
22925464
28.

CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma.

Giovannini C, Gramantieri L, Minguzzi M, Fornari F, Chieco P, Grazi GL, Bolondi L.

Am J Pathol. 2012 Aug;181(2):413-22. doi: 10.1016/j.ajpath.2012.04.019. Epub 2012 Jun 15.

PMID:
22705236
29.

Role of polyphenols in cell death control.

Giovannini C, Masella R.

Nutr Neurosci. 2012 May;15(3):134-49. doi: 10.1179/1476830512Y.0000000006. Epub 2012 Mar 26. Review.

PMID:
22584012
30.

Protocatechuic acid and human disease prevention: biological activities and molecular mechanisms.

Masella R, Santangelo C, D'Archivio M, Li Volti G, Giovannini C, Galvano F.

Curr Med Chem. 2012;19(18):2901-17. Review.

PMID:
22519395
31.

CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP.

Huezo-Diaz P, Perroud N, Spencer EP, Smith R, Sim S, Virding S, Uher R, Gunasinghe C, Gray J, Campbell D, Hauser J, Maier W, Marusic A, Rietschel M, Perez J, Giovannini C, Mors O, Mendlewicz J, McGuffin P, Farmer AE, Ingelman-Sundberg M, Craig IW, Aitchison KJ.

J Psychopharmacol. 2012 Mar;26(3):398-407. doi: 10.1177/0269881111414451. Epub 2011 Sep 17.

PMID:
21926427
32.

OxLDL induced p53-dependent apoptosis by activating p38MAPK and PKCδ signaling pathways in J774A.1 macrophage cells.

Giovannini C, Varì R, Scazzocchio B, Sanchez M, Santangelo C, Filesi C, D'Archivio M, Masella R.

J Mol Cell Biol. 2011 Oct;3(5):316-8. doi: 10.1093/jmcb/mjr019. Epub 2011 Sep 14. No abstract available.

PMID:
21920989
33.

Cyanidin-3-O-β-glucoside and protocatechuic acid exert insulin-like effects by upregulating PPARγ activity in human omental adipocytes.

Scazzocchio B, Varì R, Filesi C, D'Archivio M, Santangelo C, Giovannini C, Iacovelli A, Silecchia G, Li Volti G, Galvano F, Masella R.

Diabetes. 2011 Sep;60(9):2234-44. doi: 10.2337/db10-1461. Epub 2011 Jul 25.

34.

Predominant role of obesity/insulin resistance in oxidative stress development.

D'Archivio M, Annuzzi G, Varì R, Filesi C, Giacco R, Scazzocchio B, Santangelo C, Giovannini C, Rivellese AA, Masella R.

Eur J Clin Invest. 2012 Jan;42(1):70-8. doi: 10.1111/j.1365-2362.2011.02558.x. Epub 2011 Jun 16.

PMID:
21679180
35.

CCAAT/enhancer-binding protein-β participates in oxidized LDL-enhanced proliferation in 3T3-L1 cells.

Santangelo C, Varì R, Scazzocchio B, Filesi C, D'Archivio M, Giovannini C, Masella R.

Biochimie. 2011 Sep;93(9):1510-9. doi: 10.1016/j.biochi.2011.05.006. Epub 2011 May 20.

PMID:
21621583
36.

Variation in GNB3 predicts response and adverse reactions to antidepressants.

Keers R, Bonvicini C, Scassellati C, Uher R, Placentino A, Giovannini C, Rietschel M, Henigsberg N, Kozel D, Mors O, Maier W, Hauser J, Souery D, Mendlewicz J, Schmäl C, Zobel A, Larsen ER, Szczepankiewicz A, Kovacic Z, Elkin A, Craig I, McGuffin P, Farmer AE, Aitchison KJ, Gennarelli M.

J Psychopharmacol. 2011 Jul;25(7):867-74. doi: 10.1177/0269881110376683. Epub 2010 Sep 8.

PMID:
20826553
37.

Protocatechuic acid induces antioxidant/detoxifying enzyme expression through JNK-mediated Nrf2 activation in murine macrophages.

Varì R, D'Archivio M, Filesi C, Carotenuto S, Scazzocchio B, Santangelo C, Giovannini C, Masella R.

J Nutr Biochem. 2011 May;22(5):409-17. doi: 10.1016/j.jnutbio.2010.03.008.

PMID:
20621462
38.

Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP.

Keers R, Uher R, Gupta B, Rietschel M, Schulze TG, Hauser J, Skibinska M, Henigsberg N, Kalember P, Maier W, Zobel A, Mors O, Kristensen AS, Kozel D, Giovannini C, Mendlewicz J, Kumar S, McGuffin P, Farmer AE, Aitchison KJ.

J Affect Disord. 2010 Dec;127(1-3):337-42. doi: 10.1016/j.jad.2010.06.011. Epub 2010 Jul 6.

PMID:
20609482
39.

Serum and plasma BDNF levels in major depression: a replication study and meta-analyses.

Bocchio-Chiavetto L, Bagnardi V, Zanardini R, Molteni R, Nielsen MG, Placentino A, Giovannini C, Rillosi L, Ventriglia M, Riva MA, Gennarelli M.

World J Biol Psychiatry. 2010 Sep;11(6):763-73. doi: 10.3109/15622971003611319.

PMID:
20334574
40.

Burnout in nonhospital psychiatric residential facilities.

Pedrini L, Magni LR, Giovannini C, Panetta V, Zacchi V, Rossi G, Placentino A.

Psychiatr Serv. 2009 Nov;60(11):1547-51. doi: 10.1176/appi.ps.60.11.1547.

PMID:
19880478
41.

[Laparoscopic splenectomy in haematological diseases: short- and medium-term results in thirty initial cases].

Carlini M, Giovannini C, Castaldi F, Cianciulli P, Sorrentino F, Mercadante E.

Chir Ital. 2009 Jul-Aug;61(4):427-33. Italian.

PMID:
19845264
42.

Suicidal ideation during treatment of depression with escitalopram and nortriptyline in genome-based therapeutic drugs for depression (GENDEP): a clinical trial.

Perroud N, Uher R, Marusic A, Rietschel M, Mors O, Henigsberg N, Hauser J, Maier W, Souery D, Placentino A, Szczepankiewicz A, Jorgensen L, Strohmaier J, Zobel A, Giovannini C, Elkin A, Gunasinghe C, Gray J, Campbell D, Gupta B, Farmer AE, McGuffin P, Aitchison KJ.

BMC Med. 2009 Oct 15;7:60. doi: 10.1186/1741-7015-7-60.

43.

History of suicide attempts among patients with depression in the GENDEP project.

Perroud N, Uher R, Hauser J, Rietschel M, Henigsberg N, Placentino A, Kozel D, Maier W, Mors O, Souery D, Dmitrzak-Weglarz M, Jorgensen L, Kovacic Z, Giovannini C, Mendlewicz J, Zobel A, Strohmaier J, McGuffin P, Aitchison KJ, Farmer A.

J Affect Disord. 2010 Jun;123(1-3):131-7. doi: 10.1016/j.jad.2009.09.001. Epub 2009 Sep 22.

PMID:
19772940
44.

Adverse reactions to antidepressants.

Uher R, Farmer A, Henigsberg N, Rietschel M, Mors O, Maier W, Kozel D, Hauser J, Souery D, Placentino A, Strohmaier J, Perroud N, Zobel A, Rajewska-Rager A, Dernovsek MZ, Larsen ER, Kalember P, Giovannini C, Barreto M, McGuffin P, Aitchison KJ.

Br J Psychiatry. 2009 Sep;195(3):202-10. doi: 10.1192/bjp.bp.108.061960. Erratum in: Br J Psychiatry. 2010 May;196(5):417.

PMID:
19721108
45.

MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells.

Fornari F, Gramantieri L, Giovannini C, Veronese A, Ferracin M, Sabbioni S, Calin GA, Grazi GL, Croce CM, Tavolari S, Chieco P, Negrini M, Bolondi L.

Cancer Res. 2009 Jul 15;69(14):5761-7. doi: 10.1158/0008-5472.CAN-08-4797. Epub 2009 Jul 7.

46.

Giant symptomatic myelolipoma of the right adrenal gland: a case report.

Dell'Avanzato R, Castaldi F, Giovannini C, Mercadante E, Cianciulli P, Carlini M.

Chir Ital. 2009 Mar-Apr;61(2):231-6.

PMID:
19536999
47.

Ureic nitrogen transformation in multi-layer soil columns treated with urease and nitrification inhibitors.

Giovannini C, Garcia-Mina JM, Ciavatta C, Marzadori C.

J Agric Food Chem. 2009 Jun 10;57(11):4883-7. doi: 10.1021/jf900264m.

PMID:
19397374
48.

Genetic predictors of response to antidepressants in the GENDEP project.

Uher R, Huezo-Diaz P, Perroud N, Smith R, Rietschel M, Mors O, Hauser J, Maier W, Kozel D, Henigsberg N, Barreto M, Placentino A, Dernovsek MZ, Schulze TG, Kalember P, Zobel A, Czerski PM, Larsen ER, Souery D, Giovannini C, Gray JM, Lewis CM, Farmer A, Aitchison KJ, McGuffin P, Craig I.

Pharmacogenomics J. 2009 Aug;9(4):225-33. doi: 10.1038/tpj.2009.12. Epub 2009 Apr 14.

PMID:
19365399
49.

Modulatory effects of polyphenols on apoptosis induction: relevance for cancer prevention.

D'Archivio M, Santangelo C, Scazzocchio B, Varì R, Filesi C, Masella R, Giovannini C.

Int J Mol Sci. 2008 Mar;9(3):213-28. Epub 2008 Feb 28.

50.

Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism.

Giovannini C, Gramantieri L, Chieco P, Minguzzi M, Lago F, Pianetti S, Ramazzotti E, Marcu KB, Bolondi L.

J Hepatol. 2009 May;50(5):969-79. doi: 10.1016/j.jhep.2008.12.032. Epub 2009 Mar 10.

PMID:
19304334

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