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Items: 1 to 50 of 407

1.

Exceptional and Durable Responses to TDM-1 After Trastuzumab Failure for Breast Cancer Skin Metastases: Potential Implications of an Immunological Sanctuary.

Giarratano T, Miglietta F, Giorgi CA, Tsvetkova V, Michieletto S, Evangelista L, Polico I, Dieci MV, Guarneri V.

Front Oncol. 2018 Dec 3;8:581. doi: 10.3389/fonc.2018.00581. eCollection 2018.

PMID:
30560092
2.

Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth.

Marchi S, Corricelli M, Branchini A, Vitto VAM, Missiroli S, Morciano G, Perrone M, Ferrarese M, Giorgi C, Pinotti M, Galluzzi L, Kroemer G, Pinton P.

EMBO J. 2018 Nov 30. pii: e99435. doi: 10.15252/embj.201899435. [Epub ahead of print]

PMID:
30504268
3.

Pylephlebitis as a Complication of Cholangitis and Sepsis in an HIV-Positive Patient.

Zardi EM, Giorgi C, Zardi DM.

Dig Dis Sci. 2018 Nov 28. doi: 10.1007/s10620-018-5391-y. [Epub ahead of print] No abstract available.

PMID:
30488240
4.

A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss.

Pozzer D, Varone E, Chernorudskiy A, Schiarea S, Missiroli S, Giorgi C, Pinton P, Canato M, Germinario E, Nogara L, Blaauw B, Zito E.

Redox Biol. 2018 Oct 26;20:354-366. doi: 10.1016/j.redox.2018.10.017. [Epub ahead of print]

5.

NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus.

Kuchay S, Saeed M, Giorgi C, Li J, Hoffmann HH, Pinton P, Rice CM, Pagano M.

Cell Rep. 2018 Oct 23;25(4):833-840.e3. doi: 10.1016/j.celrep.2018.09.088.

6.

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.

Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G.

Cell Death Differ. 2018 Nov;25(11):1885-1904. doi: 10.1038/s41418-018-0213-5. Epub 2018 Oct 15.

7.

Publisher Correction: The machineries, regulation and cellular functions of mitochondrial calcium.

Giorgi C, Marchi S, Pinton P.

Nat Rev Mol Cell Biol. 2018 Nov;19(11):746. doi: 10.1038/s41580-018-0066-2.

PMID:
30250295
8.

BRAZIL ROAD-KILL: a data set of wildlife terrestrial vertebrate road-kills.

Grilo C, Coimbra MR, Cerqueira RC, Barbosa P, Dornas RAP, Gonçalves LO, Teixeira FZ, Coelho IP, Schmidt BR, Pacheco DLK, Schuck G, Esperando IB, Anza JA, Beduschi J, Oliveira NR, Pinheiro PF, Bager A, Secco H, Guerreiro M, Carvalho CF, Veloso AC, Custódio AEI, Marçal O Jr, Ciocheti G, Assis J, Ribeiro MC, Francisco BSS, Cherem JJ, Trigo TC, Jardim MMA, Franceschi IC, Espinosa C, Tirelli FP, Rocha VJ, Sekiama ML, Barbosa GP, Rossi HR, Moreira TC, Cervini M, Rosa CA, Silva LG, Ferreira CMM, César A, Casella J, Mendes SL, Zina J, Bastos DFO, Souza RAT, Hartmann PA, Deffaci ACG, Mulinari J, Luzzi SC, Rezzadori T, Kolcenti C, Reis TX, Fonseca VSC, Giorgi CF, Migliorini RP, Kasper CB, Bueno C, Sobanski M, Pereira APFG, Andrade FAG, Fernandes MEB, Corrêa LLC, Nepomuceno A, Banhos A, Hannibal W, Fonseca R, Costa LA, Medici EP, Croce A, Werther K, Oliveira JP, Ribeiro JM, de Santi M, Kawanami AE, Perles L, do Couto C, Figueiró DS, Eizirik E, Correia AA Jr, Corrêa FM, Queirolo D, Quagliatto AL, Saranholi BH, Galetti PM Jr, Rodriguez-Castro KG, Braz VS, França FGR, Buss G, Rezini JA, Lion MB, Cheida CC, Lacerda ACR, Freitas CH, Venâncio F, Adania CH, Batisteli AF, Hegel CGZ, Mantovani JA, Rodrigues FHG, Bagatini T, Curi NHA, Emmert L, Erdmann RH, Costa RRGF, Martinelli A, Santos CVF, Kindel A.

Ecology. 2018 Nov;99(11):2625. doi: 10.1002/ecy.2464. Epub 2018 Sep 19.

PMID:
30229895
9.

The machineries, regulation and cellular functions of mitochondrial calcium.

Giorgi C, Marchi S, Pinton P.

Nat Rev Mol Cell Biol. 2018 Nov;19(11):713-730. doi: 10.1038/s41580-018-0052-8. Review. Erratum in: Nat Rev Mol Cell Biol. 2018 Sep 24;:.

PMID:
30143745
10.

Regulation of PKCβ levels and autophagy by PML is essential for high-glucose-dependent mesenchymal stem cell adipogenesis.

Morganti C, Missiroli S, Lebiedzinska-Arciszewska M, Ferroni L, Morganti L, Perrone M, Ramaccini D, Occhionorelli S, Zavan B, Wieckowski MR, Giorgi C.

Int J Obes (Lond). 2018 Aug 6. doi: 10.1038/s41366-018-0167-1. [Epub ahead of print]

PMID:
30082750
11.

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, Patalas-Krawczyk P, Borchard S, Jędrak P, Pierzynowska K, Szymański J, Wang DQ, Portincasa P, Węgrzyn G, Zischka H, Dobrzyn P, Bonora M, Duszynski J, Rimessi A, Karkucinska-Wieckowska A, Dobrzyn A, Szabadkai G, Zavan B, Oliveira PJ, Sardao VA, Pinton P, Wieckowski MR.

Int Rev Cell Mol Biol. 2018;340:209-344. doi: 10.1016/bs.ircmb.2018.05.006. Epub 2018 Jun 22.

PMID:
30072092
12.

Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction.

Morciano G, Preti D, Pedriali G, Aquila G, Missiroli S, Fantinati A, Caroccia N, Pacifico S, Bonora M, Talarico A, Morganti C, Rizzo P, Ferrari R, Wieckowski MR, Campo G, Giorgi C, Trapella C, Pinton P.

J Med Chem. 2018 Aug 23;61(16):7131-7143. doi: 10.1021/acs.jmedchem.8b00278. Epub 2018 Aug 9.

PMID:
30060655
13.

STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses.

Avalle L, Camporeale A, Morciano G, Caroccia N, Ghetti E, Orecchia V, Viavattene D, Giorgi C, Pinton P, Poli V.

Cell Death Differ. 2018 Jul 24. doi: 10.1038/s41418-018-0171-y. [Epub ahead of print]

PMID:
30042492
14.

Differences in carotid atherosclerosis between patients with ankylosing spondylitis treated with tumor necrosis factor-α antagonists and healthy matched controls.

Zardi EM, Pipita ME, Giorgi C, Lichinchi D, Zardi DM, Afeltra A.

Medicine (Baltimore). 2018 Jul;97(27):e11250. doi: 10.1097/MD.0000000000011250.

15.

Patterns of Fertility Preservation and Pregnancy Outcome After Breast Cancer at a Large Comprehensive Cancer Center.

Dieci MV, Ghiotto C, Barbieri C, Griguolo G, Saccardi C, Gangemi M, Pluchinotta A, Di Liso E, Giorgi CA, Giarratano T, Tasca G, Vernaci G, Faggioni G, Conte P, Guarneri V.

J Womens Health (Larchmt). 2018 Jul 2. doi: 10.1089/jwh.2018.6986. [Epub ahead of print]

PMID:
29963941
16.

Diagnostic approach to neuropsychiatric lupus erythematosus: what should we do?

Zardi EM, Giorgi C, Zardi DM.

Postgrad Med. 2018 Aug;130(6):536-547. doi: 10.1080/00325481.2018.1492309. Epub 2018 Jul 9. Review.

PMID:
29940795
17.

Immune characterization of breast cancer metastases: prognostic implications.

Dieci MV, Tsvetkova V, Orvieto E, Piacentini F, Ficarra G, Griguolo G, Miglietta F, Giarratano T, Omarini C, Bonaguro S, Cappellesso R, Aliberti C, Vernaci G, Giorgi CA, Faggioni G, Tasca G, Conte P, Guarneri V.

Breast Cancer Res. 2018 Jun 22;20(1):62. doi: 10.1186/s13058-018-1003-1.

18.

Arc 3' UTR Splicing Leads to Dual and Antagonistic Effects in Fine-Tuning Arc Expression Upon BDNF Signaling.

Paolantoni C, Ricciardi S, De Paolis V, Okenwa C, Catalanotto C, Ciotti MT, Cattaneo A, Cogoni C, Giorgi C.

Front Mol Neurosci. 2018 Apr 27;11:145. doi: 10.3389/fnmol.2018.00145. eCollection 2018.

19.

Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings.

Morciano G, Marchi S, Morganti C, Sbano L, Bittremieux M, Kerkhofs M, Corricelli M, Danese A, Karkucinska-Wieckowska A, Wieckowski MR, Bultynck G, Giorgi C, Pinton P.

Neoplasia. 2018 May;20(5):510-523. doi: 10.1016/j.neo.2018.03.005. Epub 2018 Apr 5. Review.

20.

Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes.

Kerkhofs M, Bittremieux M, Morciano G, Giorgi C, Pinton P, Parys JB, Bultynck G.

Cell Death Dis. 2018 Feb 28;9(3):334. doi: 10.1038/s41419-017-0179-0. Review.

21.

Mitochondria-associated membranes (MAMs) and inflammation.

Missiroli S, Patergnani S, Caroccia N, Pedriali G, Perrone M, Previati M, Wieckowski MR, Giorgi C.

Cell Death Dis. 2018 Feb 28;9(3):329. doi: 10.1038/s41419-017-0027-2. Review.

22.

Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics.

Janikiewicz J, Szymański J, Malinska D, Patalas-Krawczyk P, Michalska B, Duszyński J, Giorgi C, Bonora M, Dobrzyn A, Wieckowski MR.

Cell Death Dis. 2018 Feb 28;9(3):332. doi: 10.1038/s41419-017-0105-5. Review.

23.

Halide and hydroxide anion binding in water.

Savastano M, Bazzicalupi C, García-Gallarín C, Giorgi C, López de la Torre MD, Pichierri F, Bianchi A, Melguizo M.

Dalton Trans. 2018 Mar 6;47(10):3329-3338. doi: 10.1039/c7dt04430e.

PMID:
29423483
24.

Calcium Dynamics as a Machine for Decoding Signals.

Giorgi C, Danese A, Missiroli S, Patergnani S, Pinton P.

Trends Cell Biol. 2018 Apr;28(4):258-273. doi: 10.1016/j.tcb.2018.01.002. Epub 2018 Feb 3. Review.

PMID:
29409699
25.

Immune Checkpoint Inhibitor Nivolumab and Radiotherapy in Pretreated Lung Cancer Patients: Efficacy and Safety of Combination.

Fiorica F, Belluomini L, Stefanelli A, Santini A, Urbini B, Giorgi C, Frassoldati A.

Am J Clin Oncol. 2018 Jan 31. doi: 10.1097/COC.0000000000000428. [Epub ahead of print]

PMID:
29389733
26.

Rare left ventricular metastasis from uveal melanoma.

Zardi EM, Cacioli G, Giorgi C, Rafano Carnà EP, Zardi DM.

Cardiol J. 2017;24(6):712-714. doi: 10.5603/CJ.2017.0150. No abstract available.

27.

Novel function of the tumor suppressor PML at ER-mitochondria sites in the control of autophagy.

Missiroli S, Bonora M, Patergnani S, Giorgi C.

Oncotarget. 2017 Jul 4;8(47):81723-81724. doi: 10.18632/oncotarget.18974. eCollection 2017 Oct 10. No abstract available.

28.

Regulation of Endoplasmic Reticulum-Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies.

Pedriali G, Rimessi A, Sbano L, Giorgi C, Wieckowski MR, Previati M, Pinton P.

Front Oncol. 2017 Aug 31;7:180. doi: 10.3389/fonc.2017.00180. eCollection 2017. Review.

29.

An ultrasound automated method for non-invasive assessment of carotid artery pulse wave velocity.

Zardi EM, Di Geso L, Afeltra A, Zardi DM, Giorgi C, Salaffi F, Carotti M, Gutierrez M, Filippucci E, Grassi W.

J Investig Med. 2018 Aug;66(6):973-979. doi: 10.1136/jim-2017-000430. Epub 2017 Sep 2.

PMID:
28866633
30.

Autophagy and mitophagy elements are increased in body fluids of multiple sclerosis-affected individuals.

Patergnani S, Castellazzi M, Bonora M, Marchi S, Casetta I, Pugliatti M, Giorgi C, Granieri E, Pinton P.

J Neurol Neurosurg Psychiatry. 2018 Apr;89(4):439-441. doi: 10.1136/jnnp-2017-316234. Epub 2017 Sep 2. No abstract available.

PMID:
28866627
31.

Alterations in Ca2+ Signalling via ER-Mitochondria Contact Site Remodelling in Cancer.

Kerkhofs M, Giorgi C, Marchi S, Seitaj B, Parys JB, Pinton P, Bultynck G, Bittremieux M.

Adv Exp Med Biol. 2017;997:225-254. doi: 10.1007/978-981-10-4567-7_17. Review.

PMID:
28815534
32.

Endoplasmic Reticulum-Mitochondria Communication Through Ca2+ Signaling: The Importance of Mitochondria-Associated Membranes (MAMs).

Marchi S, Bittremieux M, Missiroli S, Morganti C, Patergnani S, Sbano L, Rimessi A, Kerkhofs M, Parys JB, Bultynck G, Giorgi C, Pinton P.

Adv Exp Med Biol. 2017;997:49-67. doi: 10.1007/978-981-10-4567-7_4. Review.

PMID:
28815521
33.

Use of luciferase probes to measure ATP in living cells and animals.

Morciano G, Sarti AC, Marchi S, Missiroli S, Falzoni S, Raffaghello L, Pistoia V, Giorgi C, Di Virgilio F, Pinton P.

Nat Protoc. 2017 Aug;12(8):1542-1562. doi: 10.1038/nprot.2017.052. Epub 2017 Jul 6.

PMID:
28683062
34.

Germline BAP1 mutations induce a Warburg effect.

Bononi A, Yang H, Giorgi C, Patergnani S, Pellegrini L, Su M, Xie G, Signorato V, Pastorino S, Morris P, Sakamoto G, Kuchay S, Gaudino G, Pass HI, Napolitano A, Pinton P, Jia W, Carbone M.

Cell Death Differ. 2017 Oct;24(10):1694-1704. doi: 10.1038/cdd.2017.95. Epub 2017 Jun 30.

35.

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation.

Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, Pellegrini L, Signorato V, Olivetto F, Pastorino S, Nasu M, Napolitano A, Gaudino G, Morris P, Sakamoto G, Ferris LK, Danese A, Raimondi A, Tacchetti C, Kuchay S, Pass HI, Affar EB, Yang H, Pinton P, Carbone M.

Nature. 2017 Jun 22;546(7659):549-553. doi: 10.1038/nature22798. Epub 2017 Jun 14.

36.

PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth.

Kuchay S, Giorgi C, Simoneschi D, Pagan J, Missiroli S, Saraf A, Florens L, Washburn MP, Collazo-Lorduy A, Castillo-Martin M, Cordon-Cardo C, Sebti SM, Pinton P, Pagano M.

Nature. 2017 Jun 22;546(7659):554-558. doi: 10.1038/nature22965. Epub 2017 Jun 14.

37.

Portopulmonary hypertension and hepatorenal syndrome. Two faces of the same coin.

Zardi EM, Zardi DM, Giorgi C, Chin D, Dobrina A.

Eur J Intern Med. 2017 Sep;43:22-27. doi: 10.1016/j.ejim.2017.05.028. Epub 2017 Jun 3. Review.

PMID:
28583409
38.

Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C-ring conformation.

Bonora M, Morganti C, Morciano G, Pedriali G, Lebiedzinska-Arciszewska M, Aquila G, Giorgi C, Rizzo P, Campo G, Ferrari R, Kroemer G, Wieckowski MR, Galluzzi L, Pinton P.

EMBO Rep. 2017 Jul;18(7):1077-1089. doi: 10.15252/embr.201643602. Epub 2017 May 31.

39.

Mechanistic Role of mPTP in Ischemia-Reperfusion Injury.

Morciano G, Bonora M, Campo G, Aquila G, Rizzo P, Giorgi C, Wieckowski MR, Pinton P.

Adv Exp Med Biol. 2017;982:169-189. doi: 10.1007/978-3-319-55330-6_9. Review.

PMID:
28551787
40.

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death.

Marchi S, Patergnani S, Missiroli S, Morciano G, Rimessi A, Wieckowski MR, Giorgi C, Pinton P.

Cell Calcium. 2018 Jan;69:62-72. doi: 10.1016/j.ceca.2017.05.003. Epub 2017 May 5. Review.

PMID:
28515000
41.

Cation, Anion and Ion-Pair Complexes with a G-3 Poly(ethylene imine) Dendrimer in Aqueous Solution.

Savastano M, Bazzicalupi C, Giorgi C, Gratteri P, Bianchi A.

Molecules. 2017 May 16;22(5). pii: E816. doi: 10.3390/molecules22050816.

42.

Other bricks for the correct construction of the mitochondrial permeability transition pore complex.

Morciano G, Bonora M, Giorgi C, Pinton P.

Cell Death Dis. 2017 Mar 23;8(3):e2698. doi: 10.1038/cddis.2017.96. No abstract available.

43.

FTY720 inhibits mesothelioma growth in vitro and in a syngeneic mouse model.

Szymiczek A, Pastorino S, Larson D, Tanji M, Pellegrini L, Xue J, Li S, Giorgi C, Pinton P, Takinishi Y, Pass HI, Furuya H, Gaudino G, Napolitano A, Carbone M, Yang H.

J Transl Med. 2017 Mar 15;15(1):58. doi: 10.1186/s12967-017-1158-z.

44.

Methods to Assess Mitochondrial Morphology in Mammalian Cells Mounting Autophagic or Mitophagic Responses.

Marchi S, Bonora M, Patergnani S, Giorgi C, Pinton P.

Methods Enzymol. 2017;588:171-186. doi: 10.1016/bs.mie.2016.09.080. Epub 2016 Nov 12.

PMID:
28237100
45.

Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells.

Profilo E, Peña-Altamira LE, Corricelli M, Castegna A, Danese A, Agrimi G, Petralla S, Giannuzzi G, Porcelli V, Sbano L, Viscomi C, Massenzio F, Palmieri EM, Giorgi C, Fiermonte G, Virgili M, Palmieri L, Zeviani M, Pinton P, Monti B, Palmieri F, Lasorsa FM.

Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1422-1435. doi: 10.1016/j.bbadis.2017.02.022. Epub 2017 Feb 21.

46.

Calcium regulates cell death in cancer: Roles of the mitochondria and mitochondria-associated membranes (MAMs).

Danese A, Patergnani S, Bonora M, Wieckowski MR, Previati M, Giorgi C, Pinton P.

Biochim Biophys Acta Bioenerg. 2017 Aug;1858(8):615-627. doi: 10.1016/j.bbabio.2017.01.003. Epub 2017 Jan 10. Review.

47.

TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry.

Sbano L, Bonora M, Marchi S, Baldassari F, Medina DL, Ballabio A, Giorgi C, Pinton P.

Sci Rep. 2017 Jan 13;7:40797. doi: 10.1038/srep40797.

48.

Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis.

Patergnani S, Fossati V, Bonora M, Giorgi C, Marchi S, Missiroli S, Rusielewicz T, Wieckowski MR, Pinton P.

Int Rev Cell Mol Biol. 2017;328:49-103. doi: 10.1016/bs.ircmb.2016.08.003. Epub 2016 Sep 28. Review.

PMID:
28069137
49.

Endoplasmic reticulum-mitochondria Ca2+ crosstalk in the control of the tumor cell fate.

Missiroli S, Danese A, Iannitti T, Patergnani S, Perrone M, Previati M, Giorgi C, Pinton P.

Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):858-864. doi: 10.1016/j.bbamcr.2016.12.024. Epub 2017 Jan 4. Review.

50.

Beyond breast specific-Graded Prognostic Assessment in patients with brain metastases from breast cancer: treatment impact on outcome.

Griguolo G, Dieci MV, Giarratano T, Giorgi CA, Orvieto E, Ghiotto C, Berti F, Della Puppa A, Falci C, Mioranza E, Tasca G, Milite N, Miglietta F, Scienza R, Conte P, Guarneri V.

J Neurooncol. 2017 Jan;131(2):369-376. doi: 10.1007/s11060-016-2309-4. Epub 2016 Nov 16.

PMID:
27853958

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