Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 33

1.

Application of Quantitative Motor Assessments in Friedreich Ataxia and Evaluation of Their Relation to Clinical Measures.

Hohenfeld C, Dogan I, Schubert R, Didszun C, Schöls L, Synofzik M, Giordano IA, Klockgether T, Schulz JB, Reilmann R, Reetz K.

Cerebellum. 2019 Aug 22. doi: 10.1007/s12311-019-01073-x. [Epub ahead of print]

PMID:
31441004
2.

Characterization of Cerebellar Atrophy and Resting State Functional Connectivity Patterns in Sporadic Adult-Onset Ataxia of Unknown Etiology (SAOA).

Jiang X, Faber J, Giordano I, Machts J, Kindler C, Dudesek A, Speck O, Kamm C, Düzel E, Jessen F, Spottke A, Vielhaber S, Boecker H, Klockgether T, Scheef L.

Cerebellum. 2019 Aug 17. doi: 10.1007/s12311-019-01072-y. [Epub ahead of print]

PMID:
31422550
3.

Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis.

Guardia A, Baiget J, Cacho M, Pérez A, Ortega-Guerra M, Nxumalo W, Khanye SD, Rullas J, Ortega F, Jiménez E, Pérez-Herrán E, Fraile-Gabaldón MT, Esquivias J, Fernández R, Porras-De Francisco E, Encinas L, Alonso M, Giordano I, Rivero C, Miguel-Siles J, Osende JG, Badiola KA, Rutledge PJ, Todd MH, Remuiñán M, Alemparte C.

J Med Chem. 2018 Dec 27;61(24):11327-11340. doi: 10.1021/acs.jmedchem.8b01533. Epub 2018 Dec 12.

PMID:
30457865
4.

Nonataxia symptoms in Friedreich Ataxia: Report from the Registry of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS).

Reetz K, Dogan I, Hohenfeld C, Didszun C, Giunti P, Mariotti C, Durr A, Boesch S, Klopstock T, Rodríguez de Rivera Garrido FJ, Schöls L, Giordano I, Bürk K, Pandolfo M, Schulz JB; EFACTS Study Group.

Neurology. 2018 Sep 4;91(10):e917-e930. doi: 10.1212/WNL.0000000000006121. Epub 2018 Aug 10.

PMID:
30097477
5.

Structural characteristics of the central nervous system in Friedreich ataxia: an in vivo spinal cord and brain MRI study.

Dogan I, Romanzetti S, Didszun C, Mirzazade S, Timmann D, Saft C, Schöls L, Synofzik M, Giordano IA, Klockgether T, Schulz JB, Reetz K.

J Neurol Neurosurg Psychiatry. 2019 May;90(5):615-617. doi: 10.1136/jnnp-2018-318422. Epub 2018 Jun 26. No abstract available.

PMID:
29945881
6.

Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.

Bozal-Basterra L, Martín-Ruíz I, Pirone L, Liang Y, Sigurðsson JO, Gonzalez-Santamarta M, Giordano I, Gabicagogeascoa E, de Luca A, Rodríguez JA, Wilkie AOM, Kohlhase J, Eastwood D, Yale C, Olsen JV, Rauchman M, Anderson KV, Sutherland JD, Barrio R.

Am J Hum Genet. 2018 Feb 1;102(2):249-265. doi: 10.1016/j.ajhg.2017.12.017.

7.

Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656).

Li X, Hernandez V, Rock FL, Choi W, Mak YSL, Mohan M, Mao W, Zhou Y, Easom EE, Plattner JJ, Zou W, Pérez-Herrán E, Giordano I, Mendoza-Losana A, Alemparte C, Rullas J, Angulo-Barturen I, Crouch S, Ortega F, Barros D, Alley MRK.

J Med Chem. 2017 Oct 12;60(19):8011-8026. doi: 10.1021/acs.jmedchem.7b00631. Epub 2017 Sep 27.

PMID:
28953378
8.

Clinical and genetic characteristics of sporadic adult-onset degenerative ataxia.

Giordano I, Harmuth F, Jacobi H, Paap B, Vielhaber S, Machts J, Schöls L, Synofzik M, Sturm M, Tallaksen C, Wedding IM, Boesch S, Eigentler A, van de Warrenburg B, van Gaalen J, Kamm C, Dudesek A, Kang JS, Timmann D, Silvestri G, Masciullo M, Klopstock T, Neuhofer C, Ganos C, Filla A, Bauer P, Tezenas du Montcel S, Klockgether T.

Neurology. 2017 Sep 5;89(10):1043-1049. doi: 10.1212/WNL.0000000000004311. Epub 2017 Aug 9.

PMID:
28794257
9.

Effects of acetyl-DL-leucine on cerebellar ataxia (ALCAT trial): study protocol for a multicenter, multinational, randomized, double-blind, placebo-controlled, crossover phase III trial.

Feil K, Adrion C, Teufel J, Bösch S, Claassen J, Giordano I, Hengel H, Jacobi H, Klockgether T, Klopstock T, Nachbauer W, Schöls L, Stendel C, Uslar E, van de Warrenburg B, Berger I, Naumann I, Bayer O, Müller HH, Mansmann U, Strupp M.

BMC Neurol. 2017 Jan 10;17(1):7. doi: 10.1186/s12883-016-0786-x.

10.

MiR-24 induces chemotherapy resistance and hypoxic advantage in breast cancer.

Roscigno G, Puoti I, Giordano I, Donnarumma E, Russo V, Affinito A, Adamo A, Quintavalle C, Todaro M, Vivanco MD, Condorelli G.

Oncotarget. 2017 Mar 21;8(12):19507-19521. doi: 10.18632/oncotarget.14470.

11.

Cognition in Friedreich's ataxia: a behavioral and multimodal imaging study.

Dogan I, Tinnemann E, Romanzetti S, Mirzazade S, Costa AS, Werner CJ, Heim S, Fedosov K, Schulz S, Timmann D, Giordano IA, Klockgether T, Schulz JB, Reetz K.

Ann Clin Transl Neurol. 2016 Jun 21;3(8):572-87. doi: 10.1002/acn3.315. eCollection 2016 Aug.

12.

Multisystemic SYNE1 ataxia: confirming the high frequency and extending the mutational and phenotypic spectrum.

Mademan I, Harmuth F, Giordano I, Timmann D, Magri S, Deconinck T, Claaßen J, Jokisch D, Genc G, Di Bella D, Romito S, Schüle R, Züchner S, Taroni F, Klockgether T, Schöls L, De Jonghe P, Bauer P, Consortium E, Baets J, Synofzik M.

Brain. 2016 Aug;139(Pt 8):e46. doi: 10.1093/brain/aww115. Epub 2016 May 19. No abstract available.

13.

Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases.

Miles TJ, Hennessy AJ, Bax B, Brooks G, Brown BS, Brown P, Cailleau N, Chen D, Dabbs S, Davies DT, Esken JM, Giordano I, Hoover JL, Jones GE, Kusalakumari Sukmar SK, Markwell RE, Minthorn EA, Rittenhouse S, Gwynn MN, Pearson ND.

Bioorg Med Chem Lett. 2016 May 15;26(10):2464-2469. doi: 10.1016/j.bmcl.2016.03.106. Epub 2016 Mar 31.

PMID:
27055939
14.

Biological and clinical characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) cohort: a cross-sectional analysis of baseline data.

Reetz K, Dogan I, Costa AS, Dafotakis M, Fedosov K, Giunti P, Parkinson MH, Sweeney MG, Mariotti C, Panzeri M, Nanetti L, Arpa J, Sanz-Gallego I, Durr A, Charles P, Boesch S, Nachbauer W, Klopstock T, Karin I, Depondt C, vom Hagen JM, Schöls L, Giordano IA, Klockgether T, Bürk K, Pandolfo M, Schulz JB.

Lancet Neurol. 2015 Feb;14(2):174-82. doi: 10.1016/S1474-4422(14)70321-7. Epub 2015 Jan 5.

PMID:
25566998
15.

Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases.

Miles TJ, Hennessy AJ, Bax B, Brooks G, Brown BS, Brown P, Cailleau N, Chen D, Dabbs S, Davies DT, Esken JM, Giordano I, Hoover JL, Huang J, Jones GE, Sukmar SK, Spitzfaden C, Markwell RE, Minthorn EA, Rittenhouse S, Gwynn MN, Pearson ND.

Bioorg Med Chem Lett. 2013 Oct 1;23(19):5437-41. doi: 10.1016/j.bmcl.2013.07.013. Epub 2013 Jul 17.

PMID:
23968823
16.

Experience in a short-term trial with 4-aminopyridine in cerebellar ataxia.

Giordano I, Bogdanow M, Jacobi H, Jahn K, Minnerop M, Schoels L, Synofzik M, Teufel J, Klockgether T.

J Neurol. 2013 Aug;260(8):2175-6. doi: 10.1007/s00415-013-7029-5. Epub 2013 Jul 4. No abstract available.

PMID:
23824358
17.

Role of histidine 148 in stability and dynamics of a highly fluorescent GFP variant.

Campanini B, Pioselli B, Raboni S, Felici P, Giordano I, D'Alfonso L, Collini M, Chirico G, Bettati S.

Biochim Biophys Acta. 2013 Apr;1834(4):770-9. doi: 10.1016/j.bbapap.2013.01.014. Epub 2013 Jan 26.

PMID:
23357652
18.

Flow-synchronized nasal intermittent positive pressure ventilation for infants <32 weeks' gestation with respiratory distress syndrome.

Gizzi C, Papoff P, Giordano I, Massenzi L, Barbàra CS, Campelli M, Panetta V, Agostino R, Moretti C.

Crit Care Res Pract. 2012;2012:301818. doi: 10.1155/2012/301818. Epub 2012 Nov 27.

19.

Predictors of survival in a Huntington's disease population from southern Italy.

Rinaldi C, Salvatore E, Giordano I, De Matteis S, Tucci T, Cinzia VR, Rossi F, Castaldo I, Morra VB, Di Maio L, Filla A, De Michele G.

Can J Neurol Sci. 2012 Jan;39(1):48-51.

PMID:
22384495
20.

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases.

Miles TJ, Axten JM, Barfoot C, Brooks G, Brown P, Chen D, Dabbs S, Davies DT, Downie DL, Eyrisch S, Gallagher T, Giordano I, Gwynn MN, Hennessy A, Hoover J, Huang J, Jones G, Markwell R, Miller WH, Minthorn EA, Rittenhouse S, Seefeld M, Pearson N.

Bioorg Med Chem Lett. 2011 Dec 15;21(24):7489-95. doi: 10.1016/j.bmcl.2011.09.117. Epub 2011 Oct 10.

PMID:
22047689
21.

Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases.

Miles TJ, Barfoot C, Brooks G, Brown P, Chen D, Dabbs S, Davies DT, Downie DL, Eyrisch S, Giordano I, Gwynn MN, Hennessy A, Hoover J, Huang J, Jones G, Markwell R, Rittenhouse S, Xiang H, Pearson N.

Bioorg Med Chem Lett. 2011 Dec 15;21(24):7483-8. doi: 10.1016/j.bmcl.2011.09.114. Epub 2011 Oct 10.

PMID:
22030032
22.

Type IIA topoisomerase inhibition by a new class of antibacterial agents.

Bax BD, Chan PF, Eggleston DS, Fosberry A, Gentry DR, Gorrec F, Giordano I, Hann MM, Hennessy A, Hibbs M, Huang J, Jones E, Jones J, Brown KK, Lewis CJ, May EW, Saunders MR, Singh O, Spitzfaden CE, Shen C, Shillings A, Theobald AJ, Wohlkonig A, Pearson ND, Gwynn MN.

Nature. 2010 Aug 19;466(7309):935-40. doi: 10.1038/nature09197. Epub 2010 Aug 4.

PMID:
20686482
23.

Target-directed synthesis of antibacterial drug candidate GSK966587.

Voight EA, Yin H, Downing SV, Calad SA, Matsuhashi H, Giordano I, Hennessy AJ, Goodman RM, Wood JL.

Org Lett. 2010 Aug 6;12(15):3422-5. doi: 10.1021/ol101235f.

PMID:
20670007
24.

Clinical and molecular features of mitochondrial DNA depletion syndromes.

Spinazzola A, Invernizzi F, Carrara F, Lamantea E, Donati A, Dirocco M, Giordano I, Meznaric-Petrusa M, Baruffini E, Ferrero I, Zeviani M.

J Inherit Metab Dis. 2009 Apr;32(2):143-58. doi: 10.1007/s10545-008-1038-z. Epub 2008 Dec 27.

PMID:
19125351
25.

Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy.

De Rosa A, Criscuolo C, Mancini P, De Martino M, Giordano IA, Pappatà S, Filla A, De Michele G.

Parkinsonism Relat Disord. 2009 Mar;15(3):242-4. doi: 10.1016/j.parkreldis.2008.05.011. Epub 2008 Jul 14.

PMID:
18621566
26.

N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: indazoles as phenol isosteres with improved pharmacokinetics.

Bamborough P, Angell RM, Bhamra I, Brown D, Bull J, Christopher JA, Cooper AW, Fazal LH, Giordano I, Hind L, Patel VK, Ranshaw LE, Sims MJ, Skone PA, Smith KJ, Vickerstaff E, Washington M.

Bioorg Med Chem Lett. 2007 Aug 1;17(15):4363-8. Epub 2007 Apr 13.

PMID:
17600705
27.

DNA fingerprinting and quality traits of Corbarino cherry-like tomato landraces.

Andreakis N, Giordano I, Pentangelo A, Fogliano V, Graziani G, Monti LM, Rao R.

J Agric Food Chem. 2004 Jun 2;52(11):3366-71.

PMID:
15161199
28.

Prevalence and chemosusceptibility of Neisseria meningitidis and Haemophilus influenzae in a population of central Italy.

Cresti S, Giordano I, Donati E, Giaccherini R, Barberi A, Cellesi C.

New Microbiol. 2003 Jul;26(3):281-8.

PMID:
12901425
29.

Diagnostic value of IgG avidity in Toxoplasma infection: comparison of 3 commercial kits.

Barberi A, Gistri A, Cappelletti F, Giordano I.

J Infect Dis. 2001 Oct 1;184(7):944-6. No abstract available.

PMID:
11550130
30.

Evaluation of PCR methods for 5S-rDNA and p30 genes to detect Toxoplasma gondii in blood and other clinical samples.

Cresti S, Ciacci C, Donati E, Giordano I, Tordini G, Barberi A.

New Microbiol. 2001 Apr;24(2):171-4.

PMID:
11346301
31.

Antioxidant activity and general fruit characteristics in different ecotypes of Corbarini small tomatoes.

Scalfi L, Fogliano V, Pentangelo A, Graziani G, Giordano I, Ritieni A.

J Agric Food Chem. 2000 Apr;48(4):1363-6.

PMID:
10775398
32.

[Mortality rate correlated to AIDS and to other causes in i.v. drug addicts].

Sabbatani S, Di Crescenzo E, Giorgi L, Giordano I.

Infez Med. 1996;4(2):93-9. Italian.

PMID:
14978378
33.

[Human need for basic exercise - the bedridden patient].

Lobler CS, de Carvalho Rodrigues EM, Giordano I, Lopes M, da Silva Mda G, Janella MI.

Rev Bras Enferm. 1978 Jan-Mar;31(1):123-34. Portuguese. No abstract available.

PMID:
261380

Supplemental Content

Loading ...
Support Center