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Items: 20

1.

Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult beta-thalassemia major.

Casu C, Chessa R, Liu A, Gupta R, Drakesmith H, Fleming R, Ginzburg YZ, MacDonald B, Rivella S.

Haematologica. 2019 Oct 3. pii: haematol.2018.212589. doi: 10.3324/haematol.2018.212589. [Epub ahead of print]

2.

Lobe specificity of iron-binding to transferrin modulates murine erythropoiesis and iron homeostasis.

Parrow NL, Li Y, Feola M, Guerra A, Casu C, Prasad P, Mammen L, Ali F, Vaicikauskas E, Rivella S, Ginzburg YZ, Fleming RE.

Blood. 2019 Aug 21. pii: blood.2018893099. doi: 10.1182/blood.2018893099. [Epub ahead of print]

PMID:
31434707
3.

Hepcidin-ferroportin axis in health and disease.

Ginzburg YZ.

Vitam Horm. 2019;110:17-45. doi: 10.1016/bs.vh.2019.01.002. Epub 2019 Feb 8. Review.

PMID:
30798811
4.

Tfr2 suppression benefits β-thalassemic erythropoiesis.

Ginzburg YZ, Fleming RE.

Blood. 2018 Nov 22;132(21):2215-2216. doi: 10.1182/blood-2018-10-876110. No abstract available.

5.

Inflammation, Hemolysis, and Erythropoiesis Lead to Competitive Regulation of Hepcidin and Possibly Systemic Iron Status in Sickle Cell Disease.

Ginzburg YZ, Glassberg J.

EBioMedicine. 2018 Aug;34:8-9. doi: 10.1016/j.ebiom.2018.07.023. Epub 2018 Jul 31. Review. No abstract available.

6.

Dysregulated iron metabolism in polycythemia vera: etiology and consequences.

Ginzburg YZ, Feola M, Zimran E, Varkonyi J, Ganz T, Hoffman R.

Leukemia. 2018 Oct;32(10):2105-2116. doi: 10.1038/s41375-018-0207-9. Epub 2018 Jul 24. Review.

7.

Serum Iron Protects from Renal Postischemic Injury.

Vaugier C, Amano MT, Chemouny JM, Dussiot M, Berrou C, Matignon M, Ben Mkaddem S, Wang PHM, Fricot A, Maciel TT, Grapton D, Mathieu JRR, Beaumont C, Peraldi MN, Peyssonnaux C, Mesnard L, Daugas E, Vrtovsnik F, Monteiro RC, Hermine O, Ginzburg YZ, Benhamou M, Camara NOS, Flamant M, Moura IC.

J Am Soc Nephrol. 2017 Dec;28(12):3605-3615. doi: 10.1681/ASN.2016080926. Epub 2017 Aug 7.

8.

Role of hepcidin-ferroportin axis in the pathophysiology, diagnosis, and treatment of anemia of chronic inflammation.

Langer AL, Ginzburg YZ.

Hemodial Int. 2017 Jun;21 Suppl 1:S37-S46. doi: 10.1111/hdi.12543. Epub 2017 Mar 22. Review.

PMID:
28328181
9.

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.

Li H, Choesang T, Bao W, Chen H, Feola M, Garcia-Santos D, Li J, Sun S, Follenzi A, Pham P, Liu J, Zhang J, Ponka P, An X, Mohandas N, Fleming RE, Rivella S, Li G, Ginzburg YZ.

Blood. 2017 Mar 16;129(11):1514-1526. doi: 10.1182/blood-2016-09-742387. Epub 2017 Feb 1. Erratum in: Blood. 2017 Dec 21;130(25):2809.

10.

Prolonged red cell storage before transfusion increases extravascular hemolysis.

Rapido F, Brittenham GM, Bandyopadhyay S, La Carpia F, L'Acqua C, McMahon DJ, Rebbaa A, Wojczyk BS, Netterwald J, Wang H, Schwartz J, Eisenberger A, Soffing M, Yeh R, Divgi C, Ginzburg YZ, Shaz BH, Sheth S, Francis RO, Spitalnik SL, Hod EA.

J Clin Invest. 2017 Jan 3;127(1):375-382. doi: 10.1172/JCI90837. Epub 2016 Dec 12.

11.

Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation.

Chen H, Choesang T, Li H, Sun S, Pham P, Bao W, Feola M, Westerman M, Li G, Follenzi A, Blanc L, Rivella S, Fleming RE, Ginzburg YZ.

Haematologica. 2016 Mar;101(3):297-308. doi: 10.3324/haematol.2015.127902. Epub 2015 Dec 3.

12.

Altered erythropoiesis and iron metabolism in carriers of thalassemia.

Guimarães JS, Cominal JG, Silva-Pinto AC, Olbina G, Ginzburg YZ, Nandi V, Westerman M, Rivella S, de Souza AM.

Eur J Haematol. 2015 Jun;94(6):511-8. doi: 10.1111/ejh.12464. Epub 2014 Nov 11.

13.

Iron dosing in kidney disease: inconsistency of evidence and clinical practice.

Gaweda AE, Ginzburg YZ, Chait Y, Germain MJ, Aronoff GR, Rachmilewitz E.

Nephrol Dial Transplant. 2015 Feb;30(2):187-96. doi: 10.1093/ndt/gfu104. Epub 2014 May 12. Review.

14.

An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia.

Dussiot M, Maciel TT, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil JA, Arlet JB, Coté F, Courtois G, Ginzburg YZ, Daniel TO, Chopra R, Sung V, Hermine O, Moura IC.

Nat Med. 2014 Apr;20(4):398-407. doi: 10.1038/nm.3468. Epub 2014 Mar 23.

PMID:
24658077
15.

Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling.

Parrow NL, Gardenghi S, Ramos P, Casu C, Grady RW, Anderson ER, Shah YM, Li H, Ginzburg YZ, Fleming RE, Rivella S.

Blood. 2012 Mar 29;119(13):3187-9. doi: 10.1182/blood-2012-01-405563. No abstract available.

PMID:
22461476
16.

Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron.

Hod EA, Brittenham GM, Billote GB, Francis RO, Ginzburg YZ, Hendrickson JE, Jhang J, Schwartz J, Sharma S, Sheth S, Sireci AN, Stephens HL, Stotler BA, Wojczyk BS, Zimring JC, Spitalnik SL.

Blood. 2011 Dec 15;118(25):6675-82. doi: 10.1182/blood-2011-08-371849. Epub 2011 Oct 20.

17.

Crosstalk between Iron Metabolism and Erythropoiesis.

Li H, Ginzburg YZ.

Adv Hematol. 2010;2010:605435. doi: 10.1155/2010/605435. Epub 2010 Jun 10.

18.

Transferrin therapy ameliorates disease in beta-thalassemic mice.

Li H, Rybicki AC, Suzuka SM, von Bonsdorff L, Breuer W, Hall CB, Cabantchik ZI, Bouhassira EE, Fabry ME, Ginzburg YZ.

Nat Med. 2010 Feb;16(2):177-82. doi: 10.1038/nm.2073. Epub 2010 Jan 24.

PMID:
20098432
19.

Exogenous iron increases hemoglobin in beta-thalassemic mice.

Ginzburg YZ, Rybicki AC, Suzuka SM, Hall CB, Breuer W, Cabantchik ZI, Bouhassira EE, Fabry ME, Nagel RL.

Exp Hematol. 2009 Feb;37(2):172-83. doi: 10.1016/j.exphem.2008.10.004. Epub 2008 Dec 6.

PMID:
19059700
20.

Murine glutathione S-transferase A1-1 in sickle transgenic mice.

Ginzburg YZ, Andorfer JH, Rybicki AC, Fabry ME, Nagel RL.

Am J Hematol. 2007 Oct;82(10):911-5.

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