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Items: 1 to 50 of 53

1.

Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity.

Tiscione SA, Vivas O, Ginsburg KS, Bers DM, Ory DS, Santana LF, Dixon RE, Dickson EJ.

J Cell Biol. 2019 Oct 10. pii: jcb.201903018. doi: 10.1083/jcb.201903018. [Epub ahead of print]

PMID:
31601621
2.

Enhanced Depolarization Drive in Failing Rabbit Ventricular Myocytes.

Hegyi B, Morotti S, Liu C, Ginsburg KS, Bossuyt J, Belardinelli L, Izu LT, Chen-Izu Y, Bányász T, Grandi E, Bers DM.

Circ Arrhythm Electrophysiol. 2019 Mar;12(3):e007061. doi: 10.1161/CIRCEP.118.007061.

PMID:
30879336
3.

Cardiotoxicity of environmental contaminant tributyltin involves myocyte oxidative stress and abnormal Ca2+ handling.

Pereira CLV, Ximenes CF, Merlo E, Sciortino AS, Monteiro JS, Moreira A, Jacobsen BB, Graceli JB, Ginsburg KS, Ribeiro Junior RF, Bers DM, Stefanon I.

Environ Pollut. 2019 Apr;247:371-382. doi: 10.1016/j.envpol.2019.01.053. Epub 2019 Jan 16.

PMID:
30690233
4.

Complex electrophysiological remodeling in postinfarction ischemic heart failure.

Hegyi B, Bossuyt J, Griffiths LG, Shimkunas R, Coulibaly Z, Jian Z, Grimsrud KN, Sondergaard CS, Ginsburg KS, Chiamvimonvat N, Belardinelli L, Varró A, Papp JG, Pollesello P, Levijoki J, Izu LT, Boyd WD, Bányász T, Bers DM, Chen-Izu Y.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E3036-E3044. doi: 10.1073/pnas.1718211115. Epub 2018 Mar 12.

5.

Altered Repolarization Reserve in Failing Rabbit Ventricular Myocytes: Calcium and β-Adrenergic Effects on Delayed- and Inward-Rectifier Potassium Currents.

Hegyi B, Bossuyt J, Ginsburg KS, Mendoza LM, Talken L, Ferrier WT, Pogwizd SM, Izu LT, Chen-Izu Y, Bers DM.

Circ Arrhythm Electrophysiol. 2018 Feb;11(2):e005852. doi: 10.1161/CIRCEP.117.005852.

6.

Stress Signaling JNK2 Crosstalk With CaMKII Underlies Enhanced Atrial Arrhythmogenesis.

Yan J, Zhao W, Thomson JK, Gao X, DeMarco DM, Carrillo E, Chen B, Wu X, Ginsburg KS, Bakhos M, Bers DM, Anderson ME, Song LS, Fill M, Ai X.

Circ Res. 2018 Mar 16;122(6):821-835. doi: 10.1161/CIRCRESAHA.117.312536. Epub 2018 Jan 19.

7.

Calcium-Dependent Arrhythmogenic Foci Created by Weakly Coupled Myocytes in the Failing Heart.

Lang D, Sato D, Jiang Y, Ginsburg KS, Ripplinger CM, Bers DM.

Circ Res. 2017 Dec 8;121(12):1379-1391. doi: 10.1161/CIRCRESAHA.117.312050. Epub 2017 Oct 2.

8.

Quantitative analysis of the Ca2+ -dependent regulation of delayed rectifier K+ current IKs in rabbit ventricular myocytes.

Bartos DC, Morotti S, Ginsburg KS, Grandi E, Bers DM.

J Physiol. 2017 Apr 1;595(7):2253-2268. doi: 10.1113/JP273676. Epub 2017 Mar 28.

9.

Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure.

Barbagallo F, Xu B, Reddy GR, West T, Wang Q, Fu Q, Li M, Shi Q, Ginsburg KS, Ferrier W, Isidori AM, Naro F, Patel HH, Bossuyt J, Bers D, Xiang YK.

Circ Res. 2016 Sep 30;119(8):931-43. doi: 10.1161/CIRCRESAHA.116.308964. Epub 2016 Aug 30.

10.

Depolarization of cardiac membrane potential synchronizes calcium sparks and waves in tissue.

Sato D, Bartos DC, Ginsburg KS, Bers DM.

Biophys J. 2014 Sep 16;107(6):1313-7. doi: 10.1016/j.bpj.2014.07.053.

11.

Targeted ablation of the histidine-rich Ca(2+)-binding protein (HRC) gene is associated with abnormal SR Ca(2+)-cycling and severe pathology under pressure-overload stress.

Park CS, Chen S, Lee H, Cha H, Oh JG, Hong S, Han P, Ginsburg KS, Jin S, Park I, Singh VP, Wang HS, Franzini-Armstrong C, Park WJ, Bers DM, Kranias EG, Cho C, Kim DH.

Basic Res Cardiol. 2013 May;108(3):344. doi: 10.1007/s00395-013-0344-2. Epub 2013 Apr 4.

12.

Cardiac Na+-Ca2+ exchanger: dynamics of Ca2+-dependent activation and deactivation in intact myocytes.

Ginsburg KS, Weber CR, Bers DM.

J Physiol. 2013 Apr 15;591(8):2067-86. doi: 10.1113/jphysiol.2013.252080. Epub 2013 Feb 11.

13.

Measuring local gradients of intramitochondrial [Ca(2+)] in cardiac myocytes during sarcoplasmic reticulum Ca(2+) release.

Lu X, Ginsburg KS, Kettlewell S, Bossuyt J, Smith GL, Bers DM.

Circ Res. 2013 Feb 1;112(3):424-31. doi: 10.1161/CIRCRESAHA.111.300501. Epub 2012 Dec 14.

14.

CaMKIIδC slows [Ca]i decline in cardiac myocytes by promoting Ca sparks.

Guo T, Zhang T, Ginsburg KS, Mishra S, Brown JH, Bers DM.

Biophys J. 2012 Jun 6;102(11):2461-70. doi: 10.1016/j.bpj.2012.04.015. Epub 2012 Jun 5.

15.

Theoretical study of L-type Ca(2+) current inactivation kinetics during action potential repolarization and early afterdepolarizations.

Morotti S, Grandi E, Summa A, Ginsburg KS, Bers DM.

J Physiol. 2012 Sep 15;590(18):4465-81. doi: 10.1113/jphysiol.2012.231886. Epub 2012 May 14.

16.

Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.

Ashpole NM, Herren AW, Ginsburg KS, Brogan JD, Johnson DE, Cummins TR, Bers DM, Hudmon A.

J Biol Chem. 2012 Jun 8;287(24):19856-69. doi: 10.1074/jbc.M111.322537. Epub 2012 Apr 18.

17.

Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2.

Xu H, Ginsburg KS, Hall DD, Zimmermann M, Stein IS, Zhang M, Tandan S, Hill JA, Horne MC, Bers D, Hell JW.

Biochemistry. 2010 Dec 7;49(48):10298-307. doi: 10.1021/bi101018c. Epub 2010 Nov 11.

18.

Interplay of voltage and Ca-dependent inactivation of L-type Ca current.

Grandi E, Morotti S, Ginsburg KS, Severi S, Bers DM.

Prog Biophys Mol Biol. 2010 Sep;103(1):44-50. doi: 10.1016/j.pbiomolbio.2010.02.001. Epub 2010 Feb 23. Review.

19.

Minding the store of Ca2+ during ischaemia/reperfusion.

Bers DM, Ginsburg KS.

Cardiovasc Res. 2010 Mar 1;85(4):641-2. doi: 10.1093/cvr/cvp423. Epub 2010 Jan 7. No abstract available.

PMID:
20056726
20.

Phospholamban overexpression in rabbit ventricular myocytes does not alter sarcoplasmic reticulum Ca transport.

Waggoner JR, Ginsburg KS, Mitton B, Haghighi K, Robbins J, Bers DM, Kranias EG.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H698-703. doi: 10.1152/ajpheart.00272.2008. Epub 2008 Dec 26.

21.

Na:Ca stoichiometry and cytosolic Ca-dependent activation of NCX in intact cardiomyocytes.

Bers DM, Ginsburg KS.

Ann N Y Acad Sci. 2007 Mar;1099:326-38. Epub 2007 Feb 15. Review.

PMID:
17303827
22.

Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function.

Gregory KN, Ginsburg KS, Bodi I, Hahn H, Marreez YM, Song Q, Padmanabhan PA, Mitton BA, Waggoner JR, Del Monte F, Park WJ, Dorn GW 2nd, Bers DM, Kranias EG.

J Mol Cell Cardiol. 2006 May;40(5):653-65.

PMID:
16600288
23.

Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury.

Sun J, Picht E, Ginsburg KS, Bers DM, Steenbergen C, Murphy E.

Circ Res. 2006 Feb 17;98(3):403-11. Epub 2006 Jan 5.

PMID:
16397145
24.

Isoproterenol does not enhance Ca-dependent Na/Ca exchange current in intact rabbit ventricular myocytes.

Ginsburg KS, Bers DM.

J Mol Cell Cardiol. 2005 Dec;39(6):972-81. Epub 2005 Oct 19.

PMID:
16242149
25.

Phospholemman-phosphorylation mediates the beta-adrenergic effects on Na/K pump function in cardiac myocytes.

Despa S, Bossuyt J, Han F, Ginsburg KS, Jia LG, Kutchai H, Tucker AL, Bers DM.

Circ Res. 2005 Aug 5;97(3):252-9. Epub 2005 Jul 7.

PMID:
16002746
26.

Transgenic rabbit model for human troponin I-based hypertrophic cardiomyopathy.

Sanbe A, James J, Tuzcu V, Nas S, Martin L, Gulick J, Osinska H, Sakthivel S, Klevitsky R, Ginsburg KS, Bers DM, Zinman B, Lakatta EG, Robbins J.

Circulation. 2005 May 10;111(18):2330-8. Epub 2005 May 2.

27.
28.

Cardiac submembrane [Na+] transients sensed by Na+-Ca2+ exchange current.

Weber CR, Ginsburg KS, Bers DM.

Circ Res. 2003 May 16;92(9):950-2. Epub 2003 Apr 17.

PMID:
12702644
29.

Chronic SR Ca2+-ATPase inhibition causes adaptive changes in cellular Ca2+ transport.

Brittsan AG, Ginsburg KS, Chu G, Yatani A, Wolska BM, Schmidt AG, Asahi M, MacLennan DH, Bers DM, Kranias EG.

Circ Res. 2003 Apr 18;92(7):769-76. Epub 2003 Mar 13.

PMID:
12637367
30.

Simultaneous measurement of [Na]i, [Ca]i, and I(NCX) in intact cardiac myocytes.

Ginsburg KS, Weber CR, Despa S, Bers DM.

Ann N Y Acad Sci. 2002 Nov;976:157-8. No abstract available.

PMID:
12502556
31.

Quantitative assessment of the SR Ca2+ leak-load relationship.

Shannon TR, Ginsburg KS, Bers DM.

Circ Res. 2002 Oct 4;91(7):594-600.

PMID:
12364387
32.

Na(+)-Ca(2+) exchange current and submembrane [Ca(2+)] during the cardiac action potential.

Weber CR, Piacentino V 3rd, Ginsburg KS, Houser SR, Bers DM.

Circ Res. 2002 Feb 8;90(2):182-9.

PMID:
11834711
33.

Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.

Weber CR, Ginsburg KS, Philipson KD, Shannon TR, Bers DM.

J Gen Physiol. 2001 Feb;117(2):119-31.

34.
37.

Reverse mode of the sarcoplasmic reticulum Ca pump limits sarcoplasmic reticulum Ca uptake in permeabilized and voltage-clamped myocytes.

Shannon TR, Ginsburg KS, Bers DM.

Ann N Y Acad Sci. 1998 Sep 16;853:350-2. No abstract available.

PMID:
10603977
38.

Ion channels as targets for insecticides.

Narahashi T, Ginsburg KS, Nagata K, Song JH, Tatebayashi H.

Neurotoxicology. 1998 Aug-Oct;19(4-5):581-90. Review.

PMID:
9745915
39.

Ca flux, contractility, and excitation-contraction coupling in hypertrophic rat ventricular myocytes.

McCall E, Ginsburg KS, Bassani RA, Shannon TR, Qi M, Samarel AM, Bers DM.

Am J Physiol. 1998 Apr;274(4):H1348-60. doi: 10.1152/ajpheart.1998.274.4.H1348.

PMID:
9575940
41.
42.

Cardiac myocyte volume, Ca2+ fluxes, and sarcoplasmic reticulum loading in pressure-overload hypertrophy.

Delbridge LM, Satoh H, Yuan W, Bassani JW, Qi M, Ginsburg KS, Samarel AM, Bers DM.

Am J Physiol. 1997 May;272(5 Pt 2):H2425-35.

PMID:
9176314
43.

Comparison of sarcolemmal calcium channel current in rabbit and rat ventricular myocytes.

Yuan W, Ginsburg KS, Bers DM.

J Physiol. 1996 Jun 15;493 ( Pt 3):733-46.

44.

The long-term clinical outcomes of Lyme disease. A population-based retrospective cohort study.

Shadick NA, Phillips CB, Logigian EL, Steere AC, Kaplan RF, Berardi VP, Duray PH, Larson MG, Wright EA, Ginsburg KS, Katz JN, Liang MH.

Ann Intern Med. 1994 Oct 15;121(8):560-7.

PMID:
8085687
45.

Recent advances in the study of mechanism of action of marine neurotoxins.

Narahashi T, Roy ML, Ginsburg KS.

Neurotoxicology. 1994 Fall;15(3):545-54. Review.

PMID:
7854588
47.

Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis.

Ginsburg KS, Liang MH, Newcomer L, Goldhaber SZ, Schur PH, Hennekens CH, Stampfer MJ.

Ann Intern Med. 1992 Dec 15;117(12):997-1002.

PMID:
1443986
48.

Sodium and GABA-activated channels as the targets of pyrethroids and cyclodienes.

Narahashi T, Frey JM, Ginsburg KS, Roy ML.

Toxicol Lett. 1992 Dec;64-65 Spec No:429-36. Review.

PMID:
1281937
49.

Microwave effects on input resistance and action potential firing of snail neurons.

Ginsburg KS, Lin JC, O'Neill WD.

IEEE Trans Biomed Eng. 1992 Oct;39(10):1011-21.

PMID:
1280617
50.

A controlled study of the prevalence of cognitive dysfunction in randomly selected patients with systemic lupus erythematosus.

Ginsburg KS, Wright EA, Larson MG, Fossel AH, Albert M, Schur PH, Liang MH.

Arthritis Rheum. 1992 Jul;35(7):776-82.

PMID:
1622416

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