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Items: 26

1.

TREM2 triggers microglial density and age-related neuronal loss.

Linnartz-Gerlach B, Bodea LG, Klaus C, Ginolhac A, Halder R, Sinkkonen L, Walter J, Colonna M, Neumann H.

Glia. 2018 Dec 11. doi: 10.1002/glia.23563. [Epub ahead of print]

PMID:
30548312
2.

Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency.

Gérard D, Schmidt F, Ginolhac A, Schmitz M, Halder R, Ebert P, Schulz MH, Sauter T, Sinkkonen L.

Nucleic Acids Res. 2018 Dec 14. doi: 10.1093/nar/gky1240. [Epub ahead of print]

PMID:
30544251
3.

Cytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets.

Kirchmeyer M, Servais FA, Hamdorf M, Nazarov PV, Ginolhac A, Halder R, Vallar L, Glanemann M, Rubie C, Lammert F, Kreis S, Behrmann I.

J Leukoc Biol. 2018 Nov;104(5):987-1002. doi: 10.1002/JLB.MA1217-499RR. Epub 2018 Aug 26.

PMID:
30145833
4.

The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies.

Rolvering C, Zimmer AD, Ginolhac A, Margue C, Kirchmeyer M, Servais F, Hermanns HM, Hergovits S, Nazarov PV, Nicot N, Kreis S, Haan S, Behrmann I, Haan C.

J Leukoc Biol. 2018 Nov;104(5):969-985. doi: 10.1002/JLB.MA1217-495R. Epub 2018 Jul 24.

PMID:
30040142
5.

The miR-371∼373 Cluster Represses Colon Cancer Initiation and Metastatic Colonization by Inhibiting the TGFBR2/ID1 Signaling Axis.

Ullmann P, Rodriguez F, Schmitz M, Meurer SK, Qureshi-Baig K, Felten P, Ginolhac A, Antunes L, Frasquilho S, Zügel N, Weiskirchen R, Haan S, Letellier E.

Cancer Res. 2018 Jul 15;78(14):3793-3808. doi: 10.1158/0008-5472.CAN-17-3003. Epub 2018 May 10.

PMID:
29748374
6.

Loss of Myosin Vb in colorectal cancer is a strong prognostic factor for disease recurrence.

Letellier E, Schmitz M, Ginolhac A, Rodriguez F, Ullmann P, Qureshi-Baig K, Frasquilho S, Antunes L, Haan S.

Br J Cancer. 2017 Nov 21;117(11):1689-1701. doi: 10.1038/bjc.2017.352. Epub 2017 Oct 12.

7.

Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines.

Rolvering C, Zimmer AD, Kozar I, Hermanns HM, Letellier E, Vallar L, Nazarov PV, Nicot N, Ginolhac A, Haan S, Behrmann I, Haan C.

Biochim Biophys Acta Mol Cell Res. 2017 Mar;1864(3):516-526. doi: 10.1016/j.bbamcr.2016.12.006. Epub 2016 Dec 9.

8.

Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production.

Ullmann P, Qureshi-Baig K, Rodriguez F, Ginolhac A, Nonnenmacher Y, Ternes D, Weiler J, Gäbler K, Bahlawane C, Hiller K, Haan S, Letellier E.

Oncotarget. 2016 Oct 4;7(40):65454-65470. doi: 10.18632/oncotarget.11772.

9.

Role of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells.

Dorosz SA, Ginolhac A, Kähne T, Naumann M, Sauter T, Salsmann A, Bueb JL.

Mediators Inflamm. 2015;2015:737310. doi: 10.1155/2015/737310. Epub 2015 Nov 17.

10.

Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse.

Der Sarkissian C, Ermini L, Schubert M, Yang MA, Librado P, Fumagalli M, Jónsson H, Bar-Gal GK, Albrechtsen A, Vieira FG, Petersen B, Ginolhac A, Seguin-Orlando A, Magnussen K, Fages A, Gamba C, Lorente-Galdos B, Polani S, Steiner C, Neuditschko M, Jagannathan V, Feh C, Greenblatt CL, Ludwig A, Abramson NI, Zimmermann W, Schafberg R, Tikhonov A, Sicheritz-Ponten T, Willerslev E, Marques-Bonet T, Ryder OA, McCue M, Rieder S, Leeb T, Slatkin M, Orlando L.

Curr Biol. 2015 Oct 5;25(19):2577-83. doi: 10.1016/j.cub.2015.08.032. Epub 2015 Sep 24.

11.

Prehistoric genomes reveal the genetic foundation and cost of horse domestication.

Schubert M, Jónsson H, Chang D, Der Sarkissian C, Ermini L, Ginolhac A, Albrechtsen A, Dupanloup I, Foucal A, Petersen B, Fumagalli M, Raghavan M, Seguin-Orlando A, Korneliussen TS, Velazquez AM, Stenderup J, Hoover CA, Rubin CJ, Alfarhan AH, Alquraishi SA, Al-Rasheid KA, MacHugh DE, Kalbfleisch T, MacLeod JN, Rubin EM, Sicheritz-Ponten T, Andersson L, Hofreiter M, Marques-Bonet T, Gilbert MT, Nielsen R, Excoffier L, Willerslev E, Shapiro B, Orlando L.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5661-9. doi: 10.1073/pnas.1416991111. Epub 2014 Dec 15.

12.

Ancient genomics.

Der Sarkissian C, Allentoft ME, Ávila-Arcos MC, Barnett R, Campos PF, Cappellini E, Ermini L, Fernández R, da Fonseca R, Ginolhac A, Hansen AJ, Jónsson H, Korneliussen T, Margaryan A, Martin MD, Moreno-Mayar JV, Raghavan M, Rasmussen M, Velasco MS, Schroeder H, Schubert M, Seguin-Orlando A, Wales N, Gilbert MT, Willerslev E, Orlando L.

Philos Trans R Soc Lond B Biol Sci. 2015 Jan 19;370(1660):20130387. doi: 10.1098/rstb.2013.0387. Review.

13.

Speciation with gene flow in equids despite extensive chromosomal plasticity.

Jónsson H, Schubert M, Seguin-Orlando A, Ginolhac A, Petersen L, Fumagalli M, Albrechtsen A, Petersen B, Korneliussen TS, Vilstrup JT, Lear T, Myka JL, Lundquist J, Miller DC, Alfarhan AH, Alquraishi SA, Al-Rasheid KA, Stagegaard J, Strauss G, Bertelsen MF, Sicheritz-Ponten T, Antczak DF, Bailey E, Nielsen R, Willerslev E, Orlando L.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18655-60. doi: 10.1073/pnas.1412627111. Epub 2014 Dec 1.

14.

Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX.

Schubert M, Ermini L, Der Sarkissian C, Jónsson H, Ginolhac A, Schaefer R, Martin MD, Fernández R, Kircher M, McCue M, Willerslev E, Orlando L.

Nat Protoc. 2014 May;9(5):1056-82. doi: 10.1038/nprot.2014.063. Epub 2014 Apr 10.

PMID:
24722405
15.

Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse.

Orlando L, Ginolhac A, Zhang G, Froese D, Albrechtsen A, Stiller M, Schubert M, Cappellini E, Petersen B, Moltke I, Johnson PL, Fumagalli M, Vilstrup JT, Raghavan M, Korneliussen T, Malaspinas AS, Vogt J, Szklarczyk D, Kelstrup CD, Vinther J, Dolocan A, Stenderup J, Velazquez AM, Cahill J, Rasmussen M, Wang X, Min J, Zazula GD, Seguin-Orlando A, Mortensen C, Magnussen K, Thompson JF, Weinstock J, Gregersen K, Røed KH, Eisenmann V, Rubin CJ, Miller DC, Antczak DF, Bertelsen MF, Brunak S, Al-Rasheid KA, Ryder O, Andersson L, Mundy J, Krogh A, Gilbert MT, Kjær K, Sicheritz-Ponten T, Jensen LJ, Olsen JV, Hofreiter M, Nielsen R, Shapiro B, Wang J, Willerslev E.

Nature. 2013 Jul 4;499(7456):74-8. doi: 10.1038/nature12323. Epub 2013 Jun 26.

PMID:
23803765
16.

mapDamage2.0: fast approximate Bayesian estimates of ancient DNA damage parameters.

Jónsson H, Ginolhac A, Schubert M, Johnson PL, Orlando L.

Bioinformatics. 2013 Jul 1;29(13):1682-4. doi: 10.1093/bioinformatics/btt193. Epub 2013 Apr 23.

17.

Mitochondrial phylogenomics of modern and ancient equids.

Vilstrup JT, Seguin-Orlando A, Stiller M, Ginolhac A, Raghavan M, Nielsen SC, Weinstock J, Froese D, Vasiliev SK, Ovodov ND, Clary J, Helgen KM, Fleischer RC, Cooper A, Shapiro B, Orlando L.

PLoS One. 2013;8(2):e55950. doi: 10.1371/journal.pone.0055950. Epub 2013 Feb 20.

18.

Improving ancient DNA read mapping against modern reference genomes.

Schubert M, Ginolhac A, Lindgreen S, Thompson JF, Al-Rasheid KA, Willerslev E, Krogh A, Orlando L.

BMC Genomics. 2012 May 10;13:178. doi: 10.1186/1471-2164-13-178.

19.

Improving the performance of true single molecule sequencing for ancient DNA.

Ginolhac A, Vilstrup J, Stenderup J, Rasmussen M, Stiller M, Shapiro B, Zazula G, Froese D, Steinmann KE, Thompson JF, Al-Rasheid KA, Gilbert TM, Willerslev E, Orlando L.

BMC Genomics. 2012 May 10;13:177. doi: 10.1186/1471-2164-13-177.

20.

Proteomic analysis of a pleistocene mammoth femur reveals more than one hundred ancient bone proteins.

Cappellini E, Jensen LJ, Szklarczyk D, Ginolhac A, da Fonseca RA, Stafford TW, Holen SR, Collins MJ, Orlando L, Willerslev E, Gilbert MT, Olsen JV.

J Proteome Res. 2012 Feb 3;11(2):917-26. doi: 10.1021/pr200721u. Epub 2011 Dec 14.

PMID:
22103443
21.

True single-molecule DNA sequencing of a pleistocene horse bone.

Orlando L, Ginolhac A, Raghavan M, Vilstrup J, Rasmussen M, Magnussen K, Steinmann KE, Kapranov P, Thompson JF, Zazula G, Froese D, Moltke I, Shapiro B, Hofreiter M, Al-Rasheid KA, Gilbert MT, Willerslev E.

Genome Res. 2011 Oct;21(10):1705-19. doi: 10.1101/gr.122747.111. Epub 2011 Jul 29.

22.

mapDamage: testing for damage patterns in ancient DNA sequences.

Ginolhac A, Rasmussen M, Gilbert MT, Willerslev E, Orlando L.

Bioinformatics. 2011 Aug 1;27(15):2153-5. doi: 10.1093/bioinformatics/btr347. Epub 2011 Jun 9.

PMID:
21659319
23.

Drugs from hidden bugs: their discovery via untapped resources.

Lefevre F, Robe P, Jarrin C, Ginolhac A, Zago C, Auriol D, Vogel TM, Simonet P, Nalin R.

Res Microbiol. 2008 Apr;159(3):153-61. doi: 10.1016/j.resmic.2007.12.011. Epub 2008 Feb 12. Review.

PMID:
18375103
24.

Type I polyketide synthases may have evolved through horizontal gene transfer.

Ginolhac A, Jarrin C, Robe P, Perrière G, Vogel TM, Simonet P, Nalin R.

J Mol Evol. 2005 Jun;60(6):716-25. Epub 2005 May 16.

PMID:
15909225
25.

Phylogenetic analysis of polyketide synthase I domains from soil metagenomic libraries allows selection of promising clones.

Ginolhac A, Jarrin C, Gillet B, Robe P, Pujic P, Tuphile K, Bertrand H, Vogel TM, Perrière G, Simonet P, Nalin R.

Appl Environ Microbiol. 2004 Sep;70(9):5522-7.

26.

Functional cytochrome oxidase histochemistry in the honeybee brain.

Armengaud C, Causse N, Aït-Oubah J, Ginolhac A, Gauthier M.

Brain Res. 2000 Mar 24;859(2):390-3.

PMID:
10719093

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