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Items: 50

1.

A role for actomyosin contractility in Notch signaling.

Hunter GL, He L, Perrimon N, Charras G, Giniger E, Baum B.

BMC Biol. 2019 Feb 11;17(1):12. doi: 10.1186/s12915-019-0625-9.

2.

Expression of a Fragment of Ankyrin 2 Disrupts the Structure of the Axon Initial Segment and Causes Axonal Degeneration in Drosophila.

Spurrier J, Shukla AK, Buckley T, Smith-Trunova S, Kuzina I, Gu Q, Giniger E.

Mol Neurobiol. 2019 Jan 21. doi: 10.1007/s12035-019-1477-6. [Epub ahead of print]

PMID:
30666562
3.

Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5.

Shukla AK, Spurrier J, Kuzina I, Giniger E.

Cell Rep. 2019 Jan 2;26(1):131-144.e4. doi: 10.1016/j.celrep.2018.12.025.

4.

Altered expression of the Cdk5 activator-like protein, Cdk5α, causes neurodegeneration, in part by accelerating the rate of aging.

Spurrier J, Shukla AK, McLinden K, Johnson K, Giniger E.

Dis Model Mech. 2018 Mar 8;11(3). pii: dmm031161. doi: 10.1242/dmm.031161.

5.

Tyrosine phosphorylation and proteolytic cleavage of Notch are required for non-canonical Notch/Abl signaling in Drosophila axon guidance.

Kannan R, Cox E, Wang L, Kuzina I, Gu Q, Giniger E.

Development. 2018 Jan 17;145(2). pii: dev151548. doi: 10.1242/dev.151548.

6.

New perspectives on the roles of Abl tyrosine kinase in axon patterning.

Kannan R, Giniger E.

Fly (Austin). 2017 Oct 2;11(4):260-270. doi: 10.1080/19336934.2017.1327106. Epub 2017 May 8. Review.

7.

The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila.

Kannan R, Song JK, Karpova T, Clarke A, Shivalkar M, Wang B, Kotlyanskaya L, Kuzina I, Gu Q, Giniger E.

Development. 2017 Feb 1;144(3):487-498. doi: 10.1242/dev.143776. Epub 2017 Jan 13.

8.

Cdk5 regulates developmental remodeling of mushroom body neurons in Drosophila.

Smith-Trunova S, Prithviraj R, Spurrier J, Kuzina I, Gu Q, Giniger E.

Dev Dyn. 2015 Dec;244(12):1550-63. doi: 10.1002/dvdy.24350. Epub 2015 Oct 14.

9.

The Abl/enabled signaling pathway regulates Golgi architecture in Drosophila photoreceptor neurons.

Kannan R, Kuzina I, Wincovitch S, Nowotarski SH, Giniger E.

Mol Biol Cell. 2014 Oct 1;25(19):2993-3005. doi: 10.1091/mbc.E14-02-0729. Epub 2014 Aug 7.

10.

Dendrite architecture organized by transcriptional control of the F-actin nucleator Spire.

Ferreira T, Ou Y, Li S, Giniger E, van Meyel DJ.

Development. 2014 Feb;141(3):650-60. doi: 10.1242/dev.099655.

11.

Of proneurotrophins and their antineurotrophic effects.

Kotlyanskaya L, McLinden KA, Giniger E.

Sci Signal. 2013 Feb 12;6(262):pe6. doi: 10.1126/scisignal.2003824. Review.

12.

Ex vivo culturing of whole, developing Drosophila brains.

Prithviraj R, Trunova S, Giniger E.

J Vis Exp. 2012 Jul 27;(65). pii: 4270. doi: 10.3791/4270.

13.

At the Fulcrum in Health and Disease: Cdk5 and the Balancing Acts of Neuronal Structure and Physiology.

McLinden KA, Trunova S, Giniger E.

Brain Disord Ther. 2012 Jul;2012(Suppl 1):001.

14.

Notch signaling and neural connectivity.

Giniger E.

Curr Opin Genet Dev. 2012 Aug;22(4):339-46. doi: 10.1016/j.gde.2012.04.003. Epub 2012 May 17. Review.

15.

Control of dendritic morphogenesis by Trio in Drosophila melanogaster.

Shivalkar M, Giniger E.

PLoS One. 2012;7(3):e33737. doi: 10.1371/journal.pone.0033737. Epub 2012 Mar 15.

16.

Absence of the Cdk5 activator p35 causes adult-onset neurodegeneration in the central brain of Drosophila.

Trunova S, Giniger E.

Dis Model Mech. 2012 Mar;5(2):210-9. doi: 10.1242/dmm.008847. Epub 2011 Dec 21.

18.

Cdk5 regulates the size of an axon initial segment-like compartment in mushroom body neurons of the Drosophila central brain.

Trunova S, Baek B, Giniger E.

J Neurosci. 2011 Jul 20;31(29):10451-62. doi: 10.1523/JNEUROSCI.0117-11.2011.

19.

How Notch establishes longitudinal axon connections between successive segments of the Drosophila CNS.

Kuzina I, Song JK, Giniger E.

Development. 2011 May;138(9):1839-49. doi: 10.1242/dev.062471. Epub 2011 Mar 29.

20.

Noncanonical Notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of Trio.

Song JK, Giniger E.

Dev Dyn. 2011 Feb;240(2):324-32. doi: 10.1002/dvdy.22525.

21.

Disabled is a bona fide component of the Abl signaling network.

Song JK, Kannan R, Merdes G, Singh J, Mlodzik M, Giniger E.

Development. 2010 Nov;137(21):3719-27. doi: 10.1242/dev.050948.

22.

The receptor protein tyrosine phosphatase PTP69D antagonizes Abl tyrosine kinase to guide axons in Drosophila.

Song JK, Giniger E, Desai CJ.

Mech Dev. 2008 Mar-Apr;125(3-4):247-56. Epub 2007 Nov 22.

23.

Molecular separation of two signaling pathways for the receptor, Notch.

Le Gall M, De Mattei C, Giniger E.

Dev Biol. 2008 Jan 15;313(2):556-67. Epub 2007 Dec 11.

24.

Lola regulates Drosophila olfactory projection neuron identity and targeting specificity.

Spletter ML, Liu J, Liu J, Su H, Giniger E, Komiyama T, Quake S, Luo L.

Neural Dev. 2007 Jul 16;2:14.

25.
26.
27.

Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola.

Horiuchi T, Giniger E, Aigaki T.

Genes Dev. 2003 Oct 15;17(20):2496-501. Epub 2003 Oct 1.

28.

Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila.

Goeke S, Greene EA, Grant PK, Gates MA, Crowner D, Aigaki T, Giniger E.

Nat Neurosci. 2003 Sep;6(9):917-24.

PMID:
12897787
29.

Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway.

Crowner D, Le Gall M, Gates MA, Giniger E.

Curr Biol. 2003 May 27;13(11):967-72.

30.
31.

Lola regulates midline crossing of CNS axons in Drosophila.

Crowner D, Madden K, Goeke S, Giniger E.

Development. 2002 Mar;129(6):1317-25.

32.

Alzheimer's disease: neurodevelopment converges with neurodegeneration.

Bothwell M, Giniger E.

Cell. 2000 Aug 4;102(3):271-3. Review. No abstract available.

33.

The Drosophila Netrin receptor Frazzled guides axons by controlling Netrin distribution.

Hiramoto M, Hiromi Y, Giniger E, Hotta Y.

Nature. 2000 Aug 24;406(6798):886-9.

PMID:
10972289
34.

The cyclin-dependent kinase Cdk5 controls multiple aspects of axon patterning in vivo.

Connell-Crowley L, Le Gall M, Vo DJ, Giniger E.

Curr Biol. 2000 May 18;10(10):599-602.

35.
36.

Let sleeping dogs lie?

Ostrander EA, Giniger E.

Nat Genet. 1999 Sep;23(1):3-4. No abstract available.

PMID:
10471483
37.

Multiple roles for notch in Drosophila myogenesis.

Fuerstenberg S, Giniger E.

Dev Biol. 1998 Sep 1;201(1):66-77.

38.

A role for Abl in Notch signaling.

Giniger E.

Neuron. 1998 Apr;20(4):667-81.

39.

Semper fidelis: what man's best friend can teach us about human biology and disease.

Ostrander EA, Giniger E.

Am J Hum Genet. 1997 Sep;61(3):475-80. Review. No abstract available.

41.

lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.

Giniger E, Tietje K, Jan LY, Jan YN.

Development. 1994 Jun;120(6):1385-98.

42.

Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte.

Clark I, Giniger E, Ruohola-Baker H, Jan LY, Jan YN.

Curr Biol. 1994 Apr 1;4(4):289-300.

PMID:
7922338
43.

Tracing neurons with a kinesin-β-galactosidase fusion protein.

Giniger E, Wells W, Jan LY, Jan YN.

Roux Arch Dev Biol. 1993 Mar;202(2):112-122. doi: 10.1007/BF00636536.

PMID:
28305652
44.
45.

GAL4 activates transcription in Drosophila.

Fischer JA, Giniger E, Maniatis T, Ptashne M.

Nature. 1988 Apr 28;332(6167):853-6.

PMID:
3128741
46.

Cooperative DNA binding of the yeast transcriptional activator GAL4.

Giniger E, Ptashne M.

Proc Natl Acad Sci U S A. 1988 Jan;85(2):382-6.

47.
48.

Specific DNA binding of GAL4, a positive regulatory protein of yeast.

Giniger E, Varnum SM, Ptashne M.

Cell. 1985 Apr;40(4):767-74.

PMID:
3886158
49.

Calcium-sensitive binding of heavy meromyosin to regulated actin in the presence of ATP.

Wagner PD, Giniger E.

J Biol Chem. 1981 Dec 25;256(24):12647-50.

50.

Hydrolysis of ATP and reversible binding to F-actin by myosin heavy chains free of all light chains.

Wagner PD, Giniger E.

Nature. 1981 Aug 6;292(5823):560-2. No abstract available.

PMID:
6454850

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