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Items: 1 to 50 of 185

1.

Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells.

Liu Z, Gu Y, Chakarov S, Bleriot C, Kwok I, Chen X, Shin A, Huang W, Dress RJ, Dutertre CA, Schlitzer A, Chen J, Ng LG, Wang H, Liu Z, Su B, Ginhoux F.

Cell. 2019 Sep 5;178(6):1509-1525.e19. doi: 10.1016/j.cell.2019.08.009.

PMID:
31491389
2.

Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung.

Schyns J, Bai Q, Ruscitti C, Radermecker C, De Schepper S, Chakarov S, Farnir F, Pirottin D, Ginhoux F, Boeckxstaens G, Bureau F, Marichal T.

Nat Commun. 2019 Sep 3;10(1):3964. doi: 10.1038/s41467-019-11843-0.

3.

Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells.

Dutertre CA, Becht E, Irac SE, Khalilnezhad A, Narang V, Khalilnezhad S, Ng PY, van den Hoogen LL, Leong JY, Lee B, Chevrier M, Zhang XM, Yong PJA, Koh G, Lum J, Howland SW, Mok E, Chen J, Larbi A, Tan HKK, Lim TKH, Karagianni P, Tzioufas AG, Malleret B, Brody J, Albani S, van Roon J, Radstake T, Newell EW, Ginhoux F.

Immunity. 2019 Sep 17;51(3):573-589.e8. doi: 10.1016/j.immuni.2019.08.008. Epub 2019 Aug 29.

PMID:
31474513
4.

TCR Sequencing Reveals the Distinct Development of Fetal and Adult Human Vγ9Vδ2 T Cells.

Papadopoulou M, Tieppo P, McGovern N, Gosselin F, Chan JKY, Goetgeluk G, Dauby N, Cogan A, Donner C, Ginhoux F, Vandekerckhove B, Vermijlen D.

J Immunol. 2019 Sep 15;203(6):1468-1479. doi: 10.4049/jimmunol.1900592. Epub 2019 Aug 14.

PMID:
31413106
5.
6.

Biphasic Impact of Prenatal Inflammation and Macrophage Depletion on the Wiring of Neocortical Inhibitory Circuits.

Thion MS, Mosser CA, Férézou I, Grisel P, Baptista S, Low D, Ginhoux F, Garel S, Audinat E.

Cell Rep. 2019 Jul 30;28(5):1119-1126.e4. doi: 10.1016/j.celrep.2019.06.086.

7.

CSF-1 controls cerebellar microglia and is required for motor function and social interaction.

Kana V, Desland FA, Casanova-Acebes M, Ayata P, Badimon A, Nabel E, Yamamuro K, Sneeboer M, Tan IL, Flanigan ME, Rose SA, Chang C, Leader A, Le Bourhis H, Sweet ES, Tung N, Wroblewska A, Lavin Y, See P, Baccarini A, Ginhoux F, Chitu V, Stanley ER, Russo SJ, Yue Z, Brown BD, Joyner AL, De Witte LD, Morishita H, Schaefer A, Merad M.

J Exp Med. 2019 Jul 26. pii: jem.20182037. doi: 10.1084/jem.20182037. [Epub ahead of print]

PMID:
31350310
8.

Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen.

Fujita K, Chakarov S, Kobayashi T, Sakamoto K, Voisin B, Duan K, Nakagawa T, Horiuchi K, Amagai M, Ginhoux F, Nagao K.

Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14714-14723. doi: 10.1073/pnas.1818907116. Epub 2019 Jul 1.

PMID:
31262819
9.

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.

Jaitin DA, Adlung L, Thaiss CA, Weiner A, Li B, Descamps H, Lundgren P, Bleriot C, Liu Z, Deczkowska A, Keren-Shaul H, David E, Zmora N, Eldar SM, Lubezky N, Shibolet O, Hill DA, Lazar MA, Colonna M, Ginhoux F, Shapiro H, Elinav E, Amit I.

Cell. 2019 Jul 25;178(3):686-698.e14. doi: 10.1016/j.cell.2019.05.054. Epub 2019 Jun 27.

PMID:
31257031
10.

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage.

Dress RJ, Dutertre CA, Giladi A, Schlitzer A, Low I, Shadan NB, Tay A, Lum J, Kairi MFBM, Hwang YY, Becht E, Cheng Y, Chevrier M, Larbi A, Newell EW, Amit I, Chen J, Ginhoux F.

Nat Immunol. 2019 Jul;20(7):852-864. doi: 10.1038/s41590-019-0420-3. Epub 2019 Jun 18.

PMID:
31213723
11.

Perturbation of the immune cells and prenatal neurogenesis by the triplication of the Erg gene in mouse models of Down syndrome.

Ishihara K, Shimizu R, Takata K, Kawashita E, Amano K, Shimohata A, Low D, Nabe T, Sago H, Alexander WS, Ginhoux F, Yamakawa K, Akiba S.

Brain Pathol. 2019 Jun 17. doi: 10.1111/bpa.12758. [Epub ahead of print]

PMID:
31206867
12.

Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate.

Kim B, Fukuda M, Lee JY, Su D, Sanu S, Silvin A, Khoo ATT, Kwon T, Liu X, Chi W, Liu X, Choi S, Wan DSY, Park SJ, Kim JS, Ginhoux F, Je HS, Chang YT.

Angew Chem Int Ed Engl. 2019 Jun 11;58(24):7972-7976. doi: 10.1002/anie.201903058. Epub 2019 Apr 30.

PMID:
31038839
13.

"Cloaking" on Time: A Cover-Up Act by Resident Tissue Macrophages.

Blériot C, Ng LG, Ginhoux F.

Cell. 2019 Apr 18;177(3):514-516. doi: 10.1016/j.cell.2019.03.042.

PMID:
31002790
14.

A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.

Janela B, Patel AA, Lau MC, Goh CC, Msallam R, Kong WT, Fehlings M, Hubert S, Lum J, Simoni Y, Malleret B, Zolezzi F, Chen J, Poidinger M, Satpathy AT, Briseno C, Wohn C, Malissen B, Murphy KM, Maini AA, Vanhoutte L, Guilliams M, Vial E, Hennequin L, Newell E, Ng LG, Musette P, Yona S, Hacini-Rachinel F, Ginhoux F.

Immunity. 2019 Apr 16;50(4):1069-1083.e8. doi: 10.1016/j.immuni.2019.03.001. Epub 2019 Mar 27.

PMID:
30926233
15.

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches.

Chakarov S, Lim HY, Tan L, Lim SY, See P, Lum J, Zhang XM, Foo S, Nakamizo S, Duan K, Kong WT, Gentek R, Balachander A, Carbajo D, Bleriot C, Malleret B, Tam JKC, Baig S, Shabeer M, Toh SES, Schlitzer A, Larbi A, Marichal T, Malissen B, Chen J, Poidinger M, Kabashima K, Bajenoff M, Ng LG, Angeli V, Ginhoux F.

Science. 2019 Mar 15;363(6432). pii: eaau0964. doi: 10.1126/science.aau0964.

PMID:
30872492
16.

Corrigendum: A Single-Cell Sequencing Guide for Immunologists.

See P, Lum J, Chen J, Ginhoux F.

Front Immunol. 2019 Feb 26;10:278. doi: 10.3389/fimmu.2019.00278. eCollection 2019.

17.

Publisher Correction: Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction.

Dick SA, Macklin JA, Nejat S, Momen A, Clemente-Casares X, Althagafi MG, Chen J, Kantores C, Hosseinzadeh S, Aronoff L, Wong A, Zaman R, Barbu I, Besla R, Lavine KJ, Razani B, Ginhoux F, Husain M, Cybulsky MI, Robbins CS, Epelman S.

Nat Immunol. 2019 May;20(5):664. doi: 10.1038/s41590-019-0363-8.

PMID:
30862954
18.

Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration.

O'Koren EG, Yu C, Klingeborn M, Wong AYW, Prigge CL, Mathew R, Kalnitsky J, Msallam RA, Silvin A, Kay JN, Bowes Rickman C, Arshavsky VY, Ginhoux F, Merad M, Saban DR.

Immunity. 2019 Mar 19;50(3):723-737.e7. doi: 10.1016/j.immuni.2019.02.007. Epub 2019 Mar 5.

PMID:
30850344
19.

Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects.

Ooi J, Langley SR, Xu X, Utami KH, Sim B, Huang Y, Harmston NP, Tay YL, Ziaei A, Zeng R, Low D, Aminkeng F, Sobota RM, Ginhoux F, Petretto E, Pouladi MA.

Cell Rep. 2019 Feb 26;26(9):2494-2508.e7. doi: 10.1016/j.celrep.2019.02.008.

20.

Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host.

Ahn M, Anderson DE, Zhang Q, Tan CW, Lim BL, Luko K, Wen M, Chia WN, Mani S, Wang LC, Ng JHJ, Sobota RM, Dutertre CA, Ginhoux F, Shi ZL, Irving AT, Wang LF.

Nat Microbiol. 2019 May;4(5):789-799. doi: 10.1038/s41564-019-0371-3. Epub 2019 Feb 25.

PMID:
30804542
21.

Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease.

Radulescu CI, Garcia-Miralles M, Sidik H, Bardile CF, Yusof NABM, Lee HU, Ho EXP, Chu CW, Layton E, Low D, De Sessions PF, Pettersson S, Ginhoux F, Pouladi MA.

Neurobiol Dis. 2019 Jul;127:65-75. doi: 10.1016/j.nbd.2019.02.011. Epub 2019 Feb 23.

PMID:
30802499
22.

Identification of CD39 as a Marker for the Circulating Malignant T-Cell Clone of Sézary Syndrome Patients.

Bensussan A, Janela B, Thonnart N, Bagot M, Musette P, Ginhoux F, Marie-Cardine A.

J Invest Dermatol. 2019 Mar;139(3):725-728. doi: 10.1016/j.jid.2018.09.026. Epub 2018 Oct 25. No abstract available.

PMID:
30798854
23.

Fat-fated microglial dysfunction.

Silvin A, Ginhoux F.

EMBO J. 2019 Jan 15;38(2). pii: e101176. doi: 10.15252/embj.2018101176. Epub 2018 Dec 19. No abstract available.

PMID:
30567721
24.

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

Lim HY, Lim SY, Tan CK, Thiam CH, Goh CC, Carbajo D, Chew SHS, See P, Chakarov S, Wang XN, Lim LH, Johnson LA, Lum J, Fong CY, Bongso A, Biswas A, Goh C, Evrard M, Yeo KP, Basu R, Wang JK, Tan Y, Jain R, Tikoo S, Choong C, Weninger W, Poidinger M, Stanley ER, Collin M, Tan NS, Ng LG, Jackson DG, Ginhoux F, Angeli V.

Immunity. 2018 Dec 18;49(6):1191. doi: 10.1016/j.immuni.2018.12.009. No abstract available.

PMID:
30566884
25.

Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction.

Dick SA, Macklin JA, Nejat S, Momen A, Clemente-Casares X, Althagafi MG, Chen J, Kantores C, Hosseinzadeh S, Aronoff L, Wong A, Zaman R, Barbu I, Besla R, Lavine KJ, Razani B, Ginhoux F, Husain M, Cybulsky MI, Robbins CS, Epelman S.

Nat Immunol. 2019 Jan;20(1):29-39. doi: 10.1038/s41590-018-0272-2. Epub 2018 Dec 11. Erratum in: Nat Immunol. 2019 Mar 12;:.

26.

Dimensionality reduction for visualizing single-cell data using UMAP.

Becht E, McInnes L, Healy J, Dutertre CA, Kwok IWH, Ng LG, Ginhoux F, Newell EW.

Nat Biotechnol. 2018 Dec 3. doi: 10.1038/nbt.4314. [Epub ahead of print]

PMID:
30531897
27.

Life Science Alliance, from the Academic Editors.

Cooper JP, Ginhoux F, Jessberger S, Overholtzer M.

Life Sci Alliance. 2018 Mar 20;1(1):e201800044. doi: 10.26508/lsa.201800044. eCollection 2018 Jan.

28.

Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells.

Loh JT, Lim TJF, Ikumi K, Matoba T, Janela B, Gunawan M, Toyama T, Bunjamin M, Ng LG, Poidinger M, Morita A, Ginhoux F, Yamazaki S, Lam KP, Su IH.

iScience. 2018 Dec 21;10:23-39. doi: 10.1016/j.isci.2018.11.019. Epub 2018 Nov 14.

29.

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.

Hammond TR, Dufort C, Dissing-Olesen L, Giera S, Young A, Wysoker A, Walker AJ, Gergits F, Segel M, Nemesh J, Marsh SE, Saunders A, Macosko E, Ginhoux F, Chen J, Franklin RJM, Piao X, McCarroll SA, Stevens B.

Immunity. 2019 Jan 15;50(1):253-271.e6. doi: 10.1016/j.immuni.2018.11.004. Epub 2018 Nov 21.

PMID:
30471926
30.

Correction: Epidermal γδ T cells originate from yolk sac hematopoiesis and clonally self-renew in the adult.

Gentek R, Ghigo C, Hoeffel G, Jorquera A, Msallam R, Wienert S, Klauschen F, Ginhoux F, Bajénoff M.

J Exp Med. 2018 Dec 3;215(12):3213. doi: 10.1084/jem.2018120611142018c. Epub 2018 Nov 23. No abstract available.

31.

The immunological anatomy of the skin.

Kabashima K, Honda T, Ginhoux F, Egawa G.

Nat Rev Immunol. 2019 Jan;19(1):19-30. doi: 10.1038/s41577-018-0084-5. Review.

PMID:
30429578
32.

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.

Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J.

Immunity. 2018 Nov 20;49(5):819-828.e6. doi: 10.1016/j.immuni.2018.09.008. Epub 2018 Nov 6.

PMID:
30413362
33.

Epidermal γδ T cells originate from yolk sac hematopoiesis and clonally self-renew in the adult.

Gentek R, Ghigo C, Hoeffel G, Jorquera A, Msallam R, Wienert S, Klauschen F, Ginhoux F, Bajénoff M.

J Exp Med. 2018 Dec 3;215(12):2994-3005. doi: 10.1084/jem.20181206. Epub 2018 Nov 8. Erratum in: J Exp Med. 2018 Nov 23;:.

34.

A Single-Cell Sequencing Guide for Immunologists.

See P, Lum J, Chen J, Ginhoux F.

Front Immunol. 2018 Oct 23;9:2425. doi: 10.3389/fimmu.2018.02425. eCollection 2018. Review. Erratum in: Front Immunol. 2019 Feb 26;10:278.

35.

Microglia and early brain development: An intimate journey.

Thion MS, Ginhoux F, Garel S.

Science. 2018 Oct 12;362(6411):185-189. doi: 10.1126/science.aat0474. Review.

PMID:
30309946
36.

Embryonic macrophages and microglia ablation alter the development of dorsal root ganglion sensory neurons in mouse embryos.

Angelim MKSC, Maia LMSS, Mouffle C, Ginhoux F, Low D, Amancio-Dos-Santos A, Makhoul J, Le Corronc H, Mangin JM, Legendre P.

Glia. 2018 Nov;66(11):2470-2486. doi: 10.1002/glia.23499. Epub 2018 Sep 25.

PMID:
30252950
37.

Publisher Correction: Studying tissue macrophages in vitro: are iPSC-derived cells the answer?

Lee CZW, Kozaki T, Ginhoux F.

Nat Rev Immunol. 2018 Nov;18(11):726. doi: 10.1038/s41577-018-0060-0.

PMID:
30166617
38.

Microglia heterogeneity along a spatio-temporal axis: More questions than answers.

Silvin A, Ginhoux F.

Glia. 2018 Oct;66(10):2045-2057. doi: 10.1002/glia.23458. Epub 2018 Aug 25. Review.

PMID:
30144321
39.

Studying tissue macrophages in vitro: are iPSC-derived cells the answer?

Lee CZW, Kozaki T, Ginhoux F.

Nat Rev Immunol. 2018 Nov;18(11):716-725. doi: 10.1038/s41577-018-0054-y. Review. Erratum in: Nat Rev Immunol. 2018 Aug 30;:.

PMID:
30140052
40.

Editorial for Cellular Immunology special issue on "Tissue Macrophages".

Ginhoux F, Guilliams M.

Cell Immunol. 2018 Aug;330:1-4. doi: 10.1016/j.cellimm.2018.07.010. No abstract available.

PMID:
30126544
41.

Macrophage depletion in cancer therapy: A double-edged sword.

Blériot C, Ginhoux F.

Cell Immunol. 2018 Sep;331:178-179. doi: 10.1016/j.cellimm.2018.07.012. Epub 2018 Aug 1. No abstract available.

PMID:
30093070
42.

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

Lim HY, Lim SY, Tan CK, Thiam CH, Goh CC, Carbajo D, Chew SHS, See P, Chakarov S, Wang XN, Lim LH, Johnson LA, Lum J, Fong CY, Bongso A, Biswas A, Goh C, Evrard M, Yeo KP, Basu R, Wang JK, Tan Y, Jain R, Tikoo S, Choong C, Weninger W, Poidinger M, Stanley RE, Collin M, Tan NS, Ng LG, Jackson DG, Ginhoux F, Angeli V.

Immunity. 2018 Aug 21;49(2):326-341.e7. doi: 10.1016/j.immuni.2018.06.008. Epub 2018 Jul 24. Erratum in: Immunity. 2018 Dec 18;49(6):1191.

43.

The mysterious origins of microglia.

Ginhoux F, Garel S.

Nat Neurosci. 2018 Jul;21(7):897-899. doi: 10.1038/s41593-018-0176-3. No abstract available.

PMID:
29942037
44.

Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis.

Giladi A, Paul F, Herzog Y, Lubling Y, Weiner A, Yofe I, Jaitin D, Cabezas-Wallscheid N, Dress R, Ginhoux F, Trumpp A, Tanay A, Amit I.

Nat Cell Biol. 2018 Jul;20(7):836-846. doi: 10.1038/s41556-018-0121-4. Epub 2018 Jun 18.

PMID:
29915358
45.

Hemogenic Endothelial Fate Mapping Reveals Dual Developmental Origin of Mast Cells.

Gentek R, Ghigo C, Hoeffel G, Bulle MJ, Msallam R, Gautier G, Launay P, Chen J, Ginhoux F, Bajénoff M.

Immunity. 2018 Jun 19;48(6):1160-1171.e5. doi: 10.1016/j.immuni.2018.04.025. Epub 2018 May 29.

46.

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency.

Simoni Y, Fehlings M, Kløverpris HN, McGovern N, Koo SL, Loh CY, Lim S, Kurioka A, Fergusson JR, Tang CL, Kam MH, Dennis K, Lim TKH, Fui ACY, Hoong CW, Chan JKY, Curotto de Lafaille M, Narayanan S, Baig S, Shabeer M, Toh SES, Tan HKK, Anicete R, Tan EH, Takano A, Klenerman P, Leslie A, Tan DSW, Tan IB, Ginhoux F, Newell EW.

Immunity. 2018 May 15;48(5):1060. doi: 10.1016/j.immuni.2018.04.028. No abstract available.

47.

Human dendritic cells.

Collin M, Ginhoux F.

Semin Cell Dev Biol. 2019 Feb;86:1-2. doi: 10.1016/j.semcdb.2018.04.015. Epub 2018 May 19. No abstract available.

PMID:
29727728
48.

Bevacizumab Promotes T-Cell-Mediated Collagen Deposition in the Mouse Model of Conjunctival Scarring.

Seet LF, Toh LZ, Chu S, Finger SN, Ginhoux F, Hong W, Wong TT.

Invest Ophthalmol Vis Sci. 2018 Mar 1;59(3):1682-1692. doi: 10.1167/iovs.17-22694.

PMID:
29625495
49.

Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis.

Mencarelli A, Khameneh HJ, Fric J, Vacca M, El Daker S, Janela B, Tang JP, Nabti S, Balachander A, Lim TS, Ginhoux F, Ricciardi-Castagnoli P, Mortellaro A.

Nat Commun. 2018 Mar 16;9(1):1102. doi: 10.1038/s41467-018-03495-3.

50.

Fetal monocytes and the origins of tissue-resident macrophages.

Hoeffel G, Ginhoux F.

Cell Immunol. 2018 Aug;330:5-15. doi: 10.1016/j.cellimm.2018.01.001. Epub 2018 Jan 12. Review.

PMID:
29475558

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