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PREhabilitation for improving QUality of recovery after ELective cardiac surgery (PREQUEL) study: protocol of a randomised controlled trial.

Yau DKW, Wong MKH, Wong WT, Gin T, Underwood MJ, Joynt GM, Lee A.

BMJ Open. 2019 May 14;9(5):e027974. doi: 10.1136/bmjopen-2018-027974.


A Novel Peptide Interfering with proBDNF-Sortilin Interaction Alleviates Chronic Inflammatory Pain.

Ho IHT, Liu X, Zou Y, Liu T, Hu W, Chan H, Tian Y, Zhang Y, Li Q, Kou S, Chan CS, Gin T, Cheng CHK, Wong SH, Yu J, Zhang L, Wu WKK, Chan MTV.

Theranostics. 2019 Feb 28;9(6):1651-1665. doi: 10.7150/thno.29703. eCollection 2019.


The phytochemical polydatin ameliorates non-alcoholic steatohepatitis by restoring lysosomal function and autophagic flux.

Chen X, Chan H, Zhang L, Liu X, Ho IHT, Zhang X, Ho J, Hu W, Tian Y, Kou S, Chan CS, Yu J, Wong SH, Gin T, Chan MTV, Sun X, Wu WKK.

J Cell Mol Med. 2019 Apr 11. doi: 10.1111/jcmm.14320. [Epub ahead of print]


Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks.

Hui DS, Chow BK, Lo T, Tsang OTY, Ko FW, Ng SS, Gin T, Chan MTV.

Eur Respir J. 2019 Apr 11;53(4). pii: 1802339. doi: 10.1183/13993003.02339-2018. Print 2019 Apr.


Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells.

Hu W, Zhang L, Li MX, Shen J, Liu XD, Xiao ZG, Wu DL, Ho IHT, Wu JCY, Cheung CKY, Zhang YC, Lau AHY, Ashktorab H, Smoot DT, Fang EF, Chan MTV, Gin T, Gong W, Wu WKK, Cho CH.

Autophagy. 2019 Apr;15(4):707-725. doi: 10.1080/15548627.2018.1557835. Epub 2019 Jan 6.


Developmental protein kinase C hyper-activation results in microcephaly and behavioral abnormalities in zebrafish.

Liu T, Shi Y, Chan MTV, Peng G, Zhang Q, Sun X, Zhu Z, Xie Y, Sham KWY, Li J, Liu X, Ho IHT, Gin T, Lu Z, Wu WKK, Cheng CHK.

Transl Psychiatry. 2018 Oct 23;8(1):232. doi: 10.1038/s41398-018-0285-5.


Oncogenes expand during evolution to withstand somatic amplification.

Wang X, Li X, Zhang L, Wong SH, Wang MHT, Tse G, Dai RZW, Nakatsu G, Coker OO, Chen Z, Ko H, Chan JYK, Liu T, Cheng CHK, Cheng ASL, To KF, Plewczynski D, Sung JJY, Yu J, Gin T, Chan MTV, Wu WKK.

Ann Oncol. 2018 Nov 1;29(11):2254-2260. doi: 10.1093/annonc/mdy397.


Rationale and design for the detection and neurological impact of cerebrovascular events in non-cardiac surgery patients cohort evaluation (NeuroVISION) study: a prospective international cohort study.

Mrkobrada M, Chan MTV, Cowan D, Spence J, Campbell D, Wang CY, Torres D, Malaga G, Sanders RD, Brown C, Sigamani A, Szczeklik W, Dmytriw AA, Agid R, Smith EE, Hill MD, Sharma M, Sharma M, Tsai S, Mensinkai A, Sahlas DJ, Guyatt G, Pettit S, Copland I, Wu WKK, Yu SCH, Gin T, Loh PS, Ramli N, Siow YL, Short TG, Waymouth E, Kumar J, Dasgupta M, Murkin JM, Fuentes M, Ortiz-Soriano V, Lindroth H, Simpson S, Sessler D, Devereaux PJ.

BMJ Open. 2018 Jul 6;8(7):e021521. doi: 10.1136/bmjopen-2018-021521.


Impact of an auditory stimulus on baseline cortisol concentrations in clinically normal dogs.

Gin TE, Puchot ML, Cook AK.

Domest Anim Endocrinol. 2018 Jul;64:66-69. doi: 10.1016/j.domaniend.2018.03.002. Epub 2018 Mar 19.


Translational genomics in pancreatic ductal adenocarcinoma: A review with re-analysis of TCGA dataset.

Ho J, Li X, Zhang L, Liang Y, Hu W, Yau JCW, Chan H, Gin T, Chan MTV, Tse G, Wu WKK.

Semin Cancer Biol. 2019 Apr;55:70-77. doi: 10.1016/j.semcancer.2018.04.004. Epub 2018 Apr 26. Review.


A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications.

Abbott TEF, Fowler AJ, Pelosi P, Gama de Abreu M, Møller AM, Canet J, Creagh-Brown B, Mythen M, Gin T, Lalu MM, Futier E, Grocott MP, Schultz MJ, Pearse RM; StEP-COMPAC Group.

Br J Anaesth. 2018 May;120(5):1066-1079. doi: 10.1016/j.bja.2018.02.007. Epub 2018 Mar 27.


Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori.

Zhang L, Hu W, Cho CH, Chan FK, Yu J, Fitzgerald JR, Cheung CK, Xiao ZG, Shen J, Li LF, Li MX, Wu JC, Ling TK, Chan JY, Ko H, Tse G, Ng SC, Yu S, Wang MH, Gin T, Ashktorab H, Smoot DT, Wong SH, Chan MT, Wu WK.

J Pathol. 2018 Apr;244(4):432-444. doi: 10.1002/path.5033. Epub 2018 Feb 28.


Exhaled air dispersion during bag-mask ventilation and sputum suctioning - Implications for infection control.

Chan MTV, Chow BK, Lo T, Ko FW, Ng SS, Gin T, Hui DS.

Sci Rep. 2018 Jan 9;8(1):198. doi: 10.1038/s41598-017-18614-1.


Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain.

Tian Y, Liu X, Jia M, Yu H, Lichtner P, Shi Y, Meng Z, Kou S, Ho IHT, Jia B, Cheng BCP, Lam CKM, Tsang S, Wong SH, Yu J, Cheng CHK, Gin T, Wu WKK, Chen Z, Chan MTV; Persistent Pain after Surgery Study Investigators.

Anesthesiology. 2018 Mar;128(3):587-597. doi: 10.1097/ALN.0000000000001977.


Effect of motor subtypes of delirium in the intensive care unit on fast-track failure after cardiac surgery.

Lee A, Mu JL, Chiu CH, Gin T, Underwood MJ, Joynt GM.

J Thorac Cardiovasc Surg. 2018 Jan;155(1):268-275.e1. doi: 10.1016/j.jtcvs.2017.08.139. Epub 2017 Sep 30.


Eosinophilia and clinical outcome of chronic obstructive pulmonary disease: a meta-analysis.

Ho J, He W, Chan MTV, Tse G, Liu T, Wong SH, Leung CCH, Wong WT, Tsang S, Zhang L, Chan RYP, Gin T, Leung J, Lau BWM, Wu WKK, Ngai SPC.

Sci Rep. 2017 Oct 18;7(1):13451. doi: 10.1038/s41598-017-13745-x.


Prevalence of virulence factors in enterotoxigenic Escherichia coli isolated from pigs with post-weaning diarrhoea in Europe.

Luppi A, Gibellini M, Gin T, Vangroenweghe F, Vandenbroucke V, Bauerfeind R, Bonilauri P, Labarque G, Hidalgo Á.

Porcine Health Manag. 2016 Sep 1;2:20. doi: 10.1186/s40813-016-0039-9. eCollection 2016.


Quantitative Analysis of the Ellipsoid Zone Intensity in Phenotypic Variations of Intermediate Age-Related Macular Degeneration.

Gin TJ, Wu Z, Chew SK, Guymer RH, Luu CD.

Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2079-2086. doi: 10.1167/iovs.16-20105.


Risk prediction models for delirium in the intensive care unit after cardiac surgery: a systematic review and independent external validation.

Lee A, Mu JL, Joynt GM, Chiu CH, Lai VKW, Gin T, Underwood MJ.

Br J Anaesth. 2017 Mar 1;118(3):391-399. doi: 10.1093/bja/aew476. Review.


Pathological Role and Diagnostic Value of Endogenous Host Defense Peptides in Adult and Neonatal Sepsis: A Systematic Review.

Ho J, Zhang L, Liu X, Wong SH, Wang MHT, Lau BWM, Ngai SPC, Chan H, Choi G, Leung CCH, Wong WT, Tsang S, Gin T, Yu J, Chan MTV, Wu WKK.

Shock. 2017 Jun;47(6):673-679. doi: 10.1097/SHK.0000000000000815. Review.


The involvement of regulatory non-coding RNAs in sepsis: a systematic review.

Ho J, Chan H, Wong SH, Wang MH, Yu J, Xiao Z, Liu X, Choi G, Leung CC, Wong WT, Li Z, Gin T, Chan MT, Wu WK.

Crit Care. 2016 Nov 28;20(1):383. Review.


Rising trends of endogenous Klebsiella pneumoniae endophthalmitis in Australia.

Odouard C, Ong D, Shah PR, Gin T, Allen PJ, Downie J, Lim LL, McCluskey P.

Clin Exp Ophthalmol. 2017 Mar;45(2):135-142. doi: 10.1111/ceo.12827. Epub 2016 Sep 15.


Autophagy in sepsis: Degradation into exhaustion?

Ho J, Yu J, Wong SH, Zhang L, Liu X, Wong WT, Leung CC, Choi G, Wang MH, Gin T, Chan MT, Wu WK.

Autophagy. 2016 Jul 2;12(7):1073-82. doi: 10.1080/15548627.2016.1179410. Epub 2016 May 12. Review.


Short-Term Changes in Postoperative Cognitive Function in Children Aged 5 to 12 Years Undergoing General Anesthesia: A Cohort Study.

Aun CS, McBride C, Lee A, Lau AS, Chung RC, Yeung CK, Lai KY, Gin T.

Medicine (Baltimore). 2016 Apr;95(14):e3250. doi: 10.1097/MD.0000000000003250.


Determinants of Serum 25-Hydroxyvitamin D Concentrations and a Screening Test for Moderate-to-Severe Hypovitaminosis D in Chinese Patients Undergoing Total Joint Arthroplasty.

Lee A, Samy W, Chiu CH, Chan SK, Gin T, Chui PT.

J Arthroplasty. 2016 Sep;31(9):1921-6. doi: 10.1016/j.arth.2016.02.052. Epub 2016 Mar 3.


Predicting postoperative cardiac complications using automated endothelial function test.

Chan MT, Gin T.

Hong Kong Med J. 2015 Dec;21 Suppl 6:17-8. No abstract available.


Effect of Hypovitaminosis D on Postoperative Pain Outcomes and Short-Term Health-Related Quality of Life After Knee Arthroplasty: A Cohort Study.

Lee A, Chan SK, Samy W, Chiu CH, Gin T.

Medicine (Baltimore). 2015 Oct;94(42):e1812. doi: 10.1097/MD.0000000000001812.


Early Magnesium Treatment After Aneurysmal Subarachnoid Hemorrhage: Individual Patient Data Meta-Analysis.

Dorhout Mees SM, Algra A, Wong GK, Poon WS, Bradford CM, Saver JL, Starkman S, Rinkel GJ, van den Bergh WM; writing groups of MASH-I, IMASH, MASH-II, MASH and FAST-MAG, van Kooten F, Dirven CM, van Gijn J, Vermeulen M, Rinkel GJ, Boet R, Chan MT, Gin T, Ng SC, Zee BC, Al-Shahi Salman R, Boiten J, Kuijsten H, Lavados PM, van Oostenbrugge RJ, Vandertop WP, Finfer S, O'Connor A, Yarad E, Firth R, McCallister R, Harrington T, Steinfort B, Faulder K, Assaad N, Morgan M, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N.

Stroke. 2015 Nov;46(11):3190-3. doi: 10.1161/STROKEAHA.115.010575. Epub 2015 Oct 13.


Cognitive outcome in acute simvastatin treatment for aneurysmal subarachnoid hemorrhage: A propensity matched analysis.

Wong GK, Wong A, Zee BC, Poon WS, Chan MT, Gin T, Siu DY, Mok VC.

J Neurol Sci. 2015 Nov 15;358(1-2):58-61. doi: 10.1016/j.jns.2015.08.013. Epub 2015 Aug 12.


Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study.

Liu X, Tian Y, Meng Z, Chen Y, Ho IH, Choy KW, Lichtner P, Wong SH, Yu J, Gin T, Wu WK, Cheng CH, Chan MT.

Anesthesiology. 2015 Oct;123(4):838-50. doi: 10.1097/ALN.0000000000000828.


High-dose simvastatin for aneurysmal subarachnoid hemorrhage: multicenter randomized controlled double-blinded clinical trial.

Wong GK, Chan DY, Siu DY, Zee BC, Poon WS, Chan MT, Gin T, Leung M; HDS-SAH Investigators.

Stroke. 2015 Feb;46(2):382-8. doi: 10.1161/STROKEAHA.114.007006. Epub 2014 Dec 16.


Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask.

Hui DS, Chow BK, Lo T, Ng SS, Ko FW, Gin T, Chan MTV.

Chest. 2015 May;147(5):1336-1343. doi: 10.1378/chest.14-1934.


Perioperative outcome after nitrous oxide anaesthesia: an ENIGMA trial.

Chan MT, Gin T.

Hong Kong Med J. 2014 Jun;20(3 Suppl 3):34-5. No abstract available.


Cyanoacrylate glue on skin lacerations near the eyes.

Gin TJ, Kam JK, Crock C.

Emerg Med Australas. 2014 Apr;26(2):200-1. doi: 10.1111/1742-6723.12169. No abstract available.


Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes.

Botto F, Alonso-Coello P, Chan MT, Villar JC, Xavier D, Srinathan S, Guyatt G, Cruz P, Graham M, Wang CY, Berwanger O, Pearse RM, Biccard BM, Abraham V, Malaga G, Hillis GS, Rodseth RN, Cook D, Polanczyk CA, Szczeklik W, Sessler DI, Sheth T, Ackland GL, Leuwer M, Garg AX, Lemanach Y, Pettit S, Heels-Ansdell D, Luratibuse G, Walsh M, Sapsford R, Schünemann HJ, Kurz A, Thomas S, Mrkobrada M, Thabane L, Gerstein H, Paniagua P, Nagele P, Raina P, Yusuf S, Devereaux PJ, Devereaux PJ, Sessler DI, Walsh M, Guyatt G, McQueen MJ, Bhandari M, Cook D, Bosch J, Buckley N, Yusuf S, Chow CK, Hillis GS, Halliwell R, Li S, Lee VW, Mooney J, Polanczyk CA, Furtado MV, Berwanger O, Suzumura E, Santucci E, Leite K, Santo JA, Jardim CA, Cavalcanti AB, Guimaraes HP, Jacka MJ, Graham M, McAlister F, McMurtry S, Townsend D, Pannu N, Bagshaw S, Bessissow A, Bhandari M, Duceppe E, Eikelboom J, Ganame J, Hankinson J, Hill S, Jolly S, Lamy A, Ling E, Magloire P, Pare G, Reddy D, Szalay D, Tittley J, Weitz J, Whitlock R, Darvish-Kazim S, Debeer J, Kavsak P, Kearon C, Mizera R, O'Donnell M, McQueen M, Pinthus J, Ribas S, Simunovic M, Tandon V, Vanhelder T, Winemaker M, Gerstein H, McDonald S, O'Bryne P, Patel A, Paul J, Punthakee Z, Raymer K, Salehian O, Spencer F, Walter S, Worster A, Adili A, Clase C, Cook D, Crowther M, Douketis J, Gangji A, Jackson P, Lim W, Lovrics P, Mazzadi S, Orovan W, Rudkowski J, Soth M, Tiboni M, Acedillo R, Garg A, Hildebrand A, Lam N, Macneil D, Mrkobrada M, Roshanov PS, Srinathan SK, Ramsey C, John PS, Thorlacius L, Siddiqui FS, Grocott HP, McKay A, Lee TW, Amadeo R, Funk D, McDonald H, Zacharias J, Villar JC, Cortés OL, Chaparro MS, Vásquez S, Castañeda A, Ferreira S, Coriat P, Monneret D, Goarin JP, Esteve CI, Royer C, Daas G, Chan MT, Choi GY, Gin T, Lit LC, Xavier D, Sigamani A, Faruqui A, Dhanpal R, Almeida S, Cherian J, Furruqh S, Abraham V, Afzal L, George P, Mala S, Schünemann H, Muti P, Vizza E, Wang CY, Ong GS, Mansor M, Tan AS, Shariffuddin II, Vasanthan V, Hashim NH, Undok AW, Ki U, Lai HY, Ahmad WA, Razack AH, Malaga G, Valderrama-Victoria V, Loza-Herrera JD, De Los Angeles Lazo M, Rotta-Rotta A, Szczeklik W, Sokolowska B, Musial J, Gorka J, Iwaszczuk P, Kozka M, Chwala M, Raczek M, Mrowiecki T, Kaczmarek B, Biccard B, Cassimjee H, Gopalan D, Kisten T, Mugabi A, Naidoo P, Naidoo R, Rodseth R, Skinner D, Torborg A, Paniagua P, Urrutia G, Maestre ML, Santaló M, Gonzalez R, Font A, Martínez C, Pelaez X, De Antonio M, Villamor JM, García JA, Ferré MJ, Popova E, Alonso-Coello P, Garutti I, Cruz P, Fernández C, Palencia M, Díaz S, Del Castillo T, Varela A, de Miguel A, Muñoz M, Piñeiro P, Cusati G, Del Barrio M, Membrillo MJ, Orozco D, Reyes F, Sapsford RJ, Barth J, Scott J, Hall A, Howell S, Lobley M, Woods J, Howard S, Fletcher J, Dewhirst N, Williams C, Rushton A, Welters I, Leuwer M, Pearse R, Ackland G, Khan A, Niebrzegowska E, Benton S, Wragg A, Archbold A, Smith A, McAlees E, Ramballi C, Macdonald N, Januszewska M, Stephens R, Reyes A, Paredes LG, Sultan P, Cain D, Whittle J, Del Arroyo AG, Sessler DI, Kurz A, Sun Z, Finnegan PS, Egan C, Honar H, Shahinyan A, Panjasawatwong K, Fu AY, Wang S, Reineks E, Nagele P, Blood J, Kalin M, Gibson D, Wildes T; Vascular events In noncardiac Surgery patIents cOhort evaluatioN (VISION) Writing Group, on behalf of The Vascular events In noncardiac Surgery patIents cOhort evaluatioN (VISION) Investigators; Appendix 1. The Vascular events In noncardiac Surgery patIents cOhort evaluatioN (VISION) Study Investigators Writing Group; Appendix 2. The Vascular events In noncardiac Surgery patIents cOhort evaluatioN Operations Committee; Vascular events In noncardiac Surgery patIents cOhort evaluatioN VISION Study Investigators.

Anesthesiology. 2014 Mar;120(3):564-78. doi: 10.1097/ALN.0000000000000113.


Spontaneous cutaneous endometriosis of the umbilicus.

Gin TJ, Gin AD, Gin D, Pham A, Cahill J.

Case Rep Dermatol. 2013 Dec 21;5(3):368-72. doi: 10.1159/000357493. eCollection 2013 Sep.


Risk of perioperative respiratory complications and postoperative morbidity in a cohort of adults exposed to passive smoking.

Lee A, Chui PT, Chiu CH, Tan PE, Tam TP, Samy W, Tong PW, Critchley LA, Gin T.

Ann Surg. 2015 Feb;261(2):297-303. doi: 10.1097/SLA.0000000000000544.


Stat3 inhibition attenuates mechanical allodynia through transcriptional regulation of chemokine expression in spinal astrocytes.

Liu X, Tian Y, Lu N, Gin T, Cheng CH, Chan MT.

PLoS One. 2013 Oct 3;8(10):e75804. doi: 10.1371/journal.pone.0075804. eCollection 2013.


Reverse survivor bias in observational studies involving cohorts: a lesson from '1:1' trauma studies.

Ho AM, Dion PW, Holcomb JB, Wong RH, Ng CS, Kamakar MK, Gin T.

Hong Kong Med J. 2013 Oct;19(5):461-3. doi: 10.12809/hkmj134077. No abstract available.


Hypnotic and sedative drugs--anything new on the horizon?

Gin T.

Curr Opin Anaesthesiol. 2013 Aug;26(4):409-13. doi: 10.1097/ACO.0b013e328362a7a3. Review.


Leukocyte DNA damage and wound infection after nitrous oxide administration: a randomized controlled trial.

Chen Y, Liu X, Cheng CH, Gin T, Leslie K, Myles P, Chan MT.

Anesthesiology. 2013 Jun;118(6):1322-31. doi: 10.1097/ALN.0b013e31829107b8.


The accuracy of urinary cotinine immunoassay test strip as an add-on test to self-reported smoking before major elective surgery.

Lee A, Gin T, Chui PT, Tan PE, Chiu CH, Tam TP, Samy W.

Nicotine Tob Res. 2013 Oct;15(10):1690-5. doi: 10.1093/ntr/ntt039. Epub 2013 Mar 20.


Exhaled air dispersion during coughing with and without wearing a surgical or N95 mask.

Hui DS, Chow BK, Chu L, Ng SS, Lee N, Gin T, Chan MT.

PLoS One. 2012;7(12):e50845. doi: 10.1371/journal.pone.0050845. Epub 2012 Dec 5.


BIS-guided anesthesia decreases postoperative delirium and cognitive decline.

Chan MT, Cheng BC, Lee TM, Gin T; CODA Trial Group.

J Neurosurg Anesthesiol. 2013 Jan;25(1):33-42. doi: 10.1097/ANA.0b013e3182712fba.


The cost-effectiveness of an outpatient anesthesia consultation clinic before surgery: a matched Hong Kong cohort study.

Lee A, Chui PT, Chiu CH, Gin T, Ho AM.

Perioper Med (Lond). 2012 Jun 27;1:3. doi: 10.1186/2047-0525-1-3. eCollection 2012.


Three-dimensional/four-dimensional volumetric ultrasound imaging of the sciatic nerve.

Karmakar M, Li X, Li J, Sala-Blanch X, Hadzic A, Gin T.

Reg Anesth Pain Med. 2012 Jan-Feb;37(1):60-6. doi: 10.1097/AAP.0b013e318232eb92.


Ultra-early (within 24 hours) aneurysm treatment after subarachnoid hemorrhage.

Wong GK, Boet R, Ng SC, Chan M, Gin T, Zee B, Poon WS.

World Neurosurg. 2012 Feb;77(2):311-5. doi: 10.1016/j.wneu.2011.09.025. Epub 2011 Nov 1.


Central retinal function as measured by the multifocal electroretinogram and flicker perimetry in early age-related macular degeneration.

Gin TJ, Luu CD, Guymer RH.

Invest Ophthalmol Vis Sci. 2011 Nov 29;52(12):9267-74. doi: 10.1167/iovs.11-8517.


Quantitative evaluation of the echo intensity of the median nerve and flexor muscles of the forearm in the young and the elderly.

Li X, Karmakar MK, Lee A, Kwok WH, Critchley LA, Gin T.

Br J Radiol. 2012 Jun;85(1014):e140-5. doi: 10.1259/bjr/30878012. Epub 2011 Oct 18.

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