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Items: 20

1.

Sources of Pathogenic Nucleic Acids in Systemic Lupus Erythematosus.

Mustelin T, Lood C, Giltiay NV.

Front Immunol. 2019 May 8;10:1028. doi: 10.3389/fimmu.2019.01028. eCollection 2019. Review.

2.

CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity.

Clark EA, Giltiay NV.

Front Immunol. 2018 Sep 28;9:2235. doi: 10.3389/fimmu.2018.02235. eCollection 2018. Review.

3.

Regulation of B-lineage cells by caspase 6.

Watanabe C, Shu GL, Giltiay NV, Clark EA.

Immunol Cell Biol. 2018 Nov;96(10):1072-1082. doi: 10.1111/imcb.12172. Epub 2018 Jun 22.

PMID:
29863787
5.

Direct regulation of IGF-binding protein 1 promoter by interleukin-1β via an insulin- and FoxO-1-independent mechanism.

Shi L, Banerjee D, Dobierzewska A, Sathishkumar S, Karakashian AA, Giltiay NV, Nikolova-Karakashian MN.

Am J Physiol Endocrinol Metab. 2016 Apr 15;310(8):E612-E623. doi: 10.1152/ajpendo.00289.2015. Epub 2016 Feb 16.

6.

Targeting antigens through blood dendritic cell antigen 2 on plasmacytoid dendritic cells promotes immunologic tolerance.

Chappell CP, Giltiay NV, Draves KE, Chen C, Hayden-Ledbetter MS, Shlomchik MJ, Kaplan DH, Clark EA.

J Immunol. 2014 Jun 15;192(12):5789-5801. doi: 10.4049/jimmunol.1303259. Epub 2014 May 14.

7.

Controlling immune responses by targeting antigens to dendritic cell subsets and B cells.

Chappell CP, Giltiay NV, Dresch C, Clark EA.

Int Immunol. 2014 Jan;26(1):3-11. doi: 10.1093/intimm/dxt059. Epub 2013 Nov 27. Review.

8.

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.

Giltiay NV, Chappell CP, Sun X, Kolhatkar N, Teal TH, Wiedeman AE, Kim J, Tanaka L, Buechler MB, Hamerman JA, Imanishi-Kari T, Clark EA, Elkon KB.

J Exp Med. 2013 Nov 18;210(12):2773-89. doi: 10.1084/jem.20122798. Epub 2013 Oct 21.

9.

Spontaneous loss of tolerance of autoreactive B cells in Act1-deficient rheumatoid factor transgenic mice.

Giltiay NV, Lu Y, Cullen JL, Jørgensen TN, Shlomchik MJ, Li X.

J Immunol. 2013 Sep 1;191(5):2155-63. doi: 10.4049/jimmunol.1300152. Epub 2013 Jul 31.

10.

B-cell selection and the development of autoantibodies.

Giltiay NV, Chappell CP, Clark EA.

Arthritis Res Ther. 2012;14 Suppl 4:S1. doi: 10.1186/ar3918. Epub 2012 Nov 2. Review.

11.

Extrafollicular B cell activation by marginal zone dendritic cells drives T cell-dependent antibody responses.

Chappell CP, Draves KE, Giltiay NV, Clark EA.

J Exp Med. 2012 Sep 24;209(10):1825-40. Epub 2012 Sep 10.

12.

Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease.

Johnson AC, Davison LM, Giltiay NV, Vareechon C, Li X, Jørgensen TN.

Eur J Immunol. 2012 Jul;42(7):1695-705. doi: 10.1002/eji.201142238.

13.

Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1beta.

Dobierzewska A, Giltiay NV, Sabapathi S, Karakashian AA, Nikolova-Karakashian MN.

J Biol Chem. 2011 Sep 16;286(37):32064-73. doi: 10.1074/jbc.M111.238030. Epub 2011 Jun 27.

14.

The adaptor molecule Act1 regulates BAFF responsiveness and self-reactive B cell selection during transitional B cell maturation.

Giltiay NV, Lu Y, Allman D, Jørgensen TN, Li X.

J Immunol. 2010 Jul 1;185(1):99-109. doi: 10.4049/jimmunol.0903312. Epub 2010 Jun 11.

15.

Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.

Liu C, Qian W, Qian Y, Giltiay NV, Lu Y, Swaidani S, Misra S, Deng L, Chen ZJ, Li X.

Sci Signal. 2009 Oct 13;2(92):ra63. doi: 10.1126/scisignal.2000382. Erratum in: Sci Signal. 2010;3(121):er3.

16.

Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice.

Deevska GM, Rozenova KA, Giltiay NV, Chambers MA, White J, Boyanovsky BB, Wei J, Daugherty A, Smart EJ, Reid MB, Merrill AH Jr, Nikolova-Karakashian M.

J Biol Chem. 2009 Mar 27;284(13):8359-68. doi: 10.1074/jbc.M807800200. Epub 2008 Dec 11.

17.

Aging in rat causes hepatic hyperresposiveness to interleukin-1beta which is mediated by neutral sphingomyelinase-2.

Rutkute K, Karakashian AA, Giltiay NV, Dobierzewska A, Nikolova-Karakashian MN.

Hepatology. 2007 Oct;46(4):1166-76.

PMID:
17668873
18.

Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1beta in hepatocytes.

Giltiay NV, Karakashian AA, Alimov AP, Ligthle S, Nikolova-Karakashian MN.

J Lipid Res. 2005 Nov;46(11):2497-505. Epub 2005 Aug 16.

19.

Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: implications for endothelial apoptosis.

Sathishkumar S, Boyanovsky B, Karakashian AA, Rozenova K, Giltiay NV, Kudrimoti M, Mohiuddin M, Ahmed MM, Nikolova-Karakashian M.

Cancer Biol Ther. 2005 Sep;4(9):979-86. Epub 2005 Sep 13.

PMID:
16096366
20.

Expression of neutral sphingomyelinase-2 (NSMase-2) in primary rat hepatocytes modulates IL-beta-induced JNK activation.

Karakashian AA, Giltiay NV, Smith GM, Nikolova-Karakashian MN.

FASEB J. 2004 Jun;18(9):968-70. Epub 2004 Apr 1.

PMID:
15059969

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