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Guidance for Studies Evaluating the Accuracy of Tuberculosis Triage Tests.

Nathavitharana RR, Yoon C, Macpherson P, Dowdy DW, Cattamanchi A, Somoskovi A, Broger T, Ottenhoff THM, Arinaminpathy N, Lonnroth K, Reither K, Cobelens F, Gilpin C, Denkinger CM, Schumacher SG.

J Infect Dis. 2019 Oct 8;220(Supplement_3):S116-S125. doi: 10.1093/infdis/jiz243.


Guidance for Studies Evaluating the Accuracy of Rapid Tuberculosis Drug-Susceptibility Tests.

Georghiou SB, Schumacher SG, Rodwell TC, Colman RE, Miotto P, Gilpin C, Ismail N, Rodrigues C, Warren R, Weyer K, Zignol M, Arafah S, Cirillo DM, Denkinger CM.

J Infect Dis. 2019 Oct 8;220(Supplement_3):S126-S135. doi: 10.1093/infdis/jiz106.


Guidance for Studies Evaluating the Accuracy of Biomarker-Based Nonsputum Tests to Diagnose Tuberculosis.

Drain PK, Gardiner J, Hannah H, Broger T, Dheda K, Fielding K, Walzl G, Kaforou M, Kranzer K, Joosten SA, Gilpin C, Weyer K, Denkinger CM, Schumacher SG.

J Infect Dis. 2019 Oct 8;220(Supplement_3):S108-S115. doi: 10.1093/infdis/jiz356.


Guidance for Studies Evaluating the Accuracy of Sputum-Based Tests to Diagnose Tuberculosis.

Schumacher SG, Wells WA, Nicol MP, Steingart KR, Theron G, Dorman SE, Pai M, Churchyard G, Scott L, Stevens W, Nabeta P, Alland D, Weyer K, Denkinger CM, Gilpin C.

J Infect Dis. 2019 Oct 8;220(Supplement_3):S99-S107. doi: 10.1093/infdis/jiz258.


Guidance for the Evaluation of Tuberculosis Diagnostics That Meet the World Health Organization (WHO) Target Product Profiles: An Introduction to WHO Process and Study Design Principles.

Denkinger CM, Schumacher SG, Gilpin C, Korobitsyn A, Wells WA, Pai M, Leeflang M, Steingart KR, Bulterys M, Schünemann H, Glaziou P, Weyer K.

J Infect Dis. 2019 Oct 8;220(Supplement_3):S91-S98. doi: 10.1093/infdis/jiz097.


The transition structure of chromatin fibers at the nanoscale probed by cryogenic electron tomography.

Zhou Z, Li K, Yan R, Yu G, Gilpin CJ, Jiang W, Irudayaraj JMK.

Nanoscale. 2019 Aug 7;11(29):13783-13789. doi: 10.1039/c9nr02042j. Epub 2019 Jun 18.


Skeletal muscle-derived exosomes regulate endothelial cell functions via reactive oxygen species-activated nuclear factor-κB signalling.

Nie Y, Sato Y, Garner RT, Kargl C, Wang C, Kuang S, Gilpin CJ, Gavin TP.

Exp Physiol. 2019 Aug;104(8):1262-1273. doi: 10.1113/EP087396. Epub 2019 Jul 10.


The Role of Novel Approaches and New Findings in the Pharmacology of Tuberculosis Medicines in Improving Treatment Outcomes.

Falzon D, Jaramillo E, Gilpin C, Weyer K.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S365-S367. doi: 10.1093/cid/ciy710. No abstract available.


Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

Ezewudo M, Borens A, Chiner-Oms Á, Miotto P, Chindelevitch L, Starks AM, Hanna D, Liwski R, Zignol M, Gilpin C, Niemann S, Kohl TA, Warren RM, Crook D, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, McNerney R, Cirillo DM, Schito M, Rodwell TC, Posey J.

Sci Rep. 2018 Oct 18;8(1):15382. doi: 10.1038/s41598-018-33731-1.


An evaluation framework for new tests that predict progression from tuberculosis infection to clinical disease.

Kik SV, Schumacher S, Cirillo DM, Churchyard G, Boehme C, Goletti D, Rangaka MX, Denkinger CM, Lienhardt C, Gilpin C, Matteelli A, Cobelens F.

Eur Respir J. 2018 Oct 25;52(4). pii: 1800946. doi: 10.1183/13993003.00946-2018. Print 2018 Oct.


Inclusion of TB diagnostics on the WHO Essential Diagnostics List.

Gilpin C, Weyer K.

Int J Tuberc Lung Dis. 2018 Aug 1;22(8):827-828. doi: 10.5588/ijtld.18.0371. No abstract available.


Genetic sequencing for surveillance of drug resistance in tuberculosis in highly endemic countries: a multi-country population-based surveillance study.

Zignol M, Cabibbe AM, Dean AS, Glaziou P, Alikhanova N, Ama C, Andres S, Barbova A, Borbe-Reyes A, Chin DP, Cirillo DM, Colvin C, Dadu A, Dreyer A, Driesen M, Gilpin C, Hasan R, Hasan Z, Hoffner S, Hussain A, Ismail N, Kamal SMM, Khanzada FM, Kimerling M, Kohl TA, Mansjö M, Miotto P, Mukadi YD, Mvusi L, Niemann S, Omar SV, Rigouts L, Schito M, Sela I, Seyfaddinova M, Skenders G, Skrahina A, Tahseen S, Wells WA, Zhurilo A, Weyer K, Floyd K, Raviglione MC.

Lancet Infect Dis. 2018 Jun;18(6):675-683. doi: 10.1016/S1473-3099(18)30073-2. Epub 2018 Mar 21. Erratum in: Lancet Infect Dis. 2018 Mar 27;:.


The World Health Organization standards for tuberculosis care and management.

Gilpin C, Korobitsyn A, Migliori GB, Raviglione MC, Weyer K.

Eur Respir J. 2018 Mar 22;51(3). pii: 1800098. doi: 10.1183/13993003.00098-2018. Print 2018 Mar. No abstract available.


A retrospective review of 48 individuals, including 12 families, molecularly diagnosed with hereditary leiomyomatosis and renal cell cancer (HLRCC).

Bhola PT, Gilpin C, Smith A, Graham GE.

Fam Cancer. 2018 Oct;17(4):615-620. doi: 10.1007/s10689-018-0076-4.


A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis.

Miotto P, Tessema B, Tagliani E, Chindelevitch L, Starks AM, Emerson C, Hanna D, Kim PS, Liwski R, Zignol M, Gilpin C, Niemann S, Denkinger CM, Fleming J, Warren RM, Crook D, Posey J, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Murray M, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, Ranganathan UDK, McNerney R, Ezewudo M, Cirillo DM, Schito M, Köser CU, Rodwell TC.

Eur Respir J. 2017 Dec 28;50(6). pii: 1701354. doi: 10.1183/13993003.01354-2017. Print 2017 Dec.


Eco-friendly (green) synthesis of magnetically active gold nanoclusters.

Kadasala NR, Lin L, Gilpin C, Wei A.

Sci Technol Adv Mater. 2017 Mar 15;18(1):210-218. doi: 10.1080/14686996.2017.1290492. eCollection 2017.


Therapeutic drug monitoring to prevent acquired drug resistance of fluoroquinolones in the treatment of tuberculosis.

Falzon D, Jaramillo E, Gilpin C, Weyer K.

Eur Respir J. 2017 Apr 26;49(4). pii: 1700317. doi: 10.1183/13993003.00317-2017. Print 2017 Apr. No abstract available.


Understanding the Impact of Water on the Miscibility and Microstructure of Amorphous Solid Dispersions: An AFM-LCR and TEM-EDX Study.

Li N, Gilpin CJ, Taylor LS.

Mol Pharm. 2017 May 1;14(5):1691-1705. doi: 10.1021/acs.molpharmaceut.6b01151. Epub 2017 Apr 19.


Current tools available for the diagnosis of drug-resistant tuberculosis.

Gilpin C, Korobitsyn A, Weyer K.

Ther Adv Infect Dis. 2016 Dec;3(6):145-151. doi: 10.1177/2049936116673553. Epub 2016 Oct 14. Review.


Protein particulate retention and microorganism recovery for rapid detection of Salmonella.

Ku S, Kreke T, Ximenes E, Foster K, Liu X, Gilpin CJ, Ladisch MR.

Biotechnol Prog. 2017 May;33(3):687-695. doi: 10.1002/btpr.2468. Epub 2017 Apr 17.


The role of novel molecular techniques for tuberculosis diagnostics in the WHO European Region.

Ehsani S, van den Boom M, Gilpin C, Dara M; WHO Regional Office for Europe.

J Public Health (Oxf). 2016 Dec 2;38(4):824-825. doi: 10.1093/pubmed/fdv200. No abstract available.


Diagnosis of opportunistic infections: HIV co-infections - tuberculosis.

Scott L, da Silva P, Boehme CC, Stevens W, Gilpin CM.

Curr Opin HIV AIDS. 2017 Mar;12(2):129-138. doi: 10.1097/COH.0000000000000345. Review.


Progeroid syndrome patients with ZMPSTE24 deficiency could benefit when treated with rapamycin and dimethylsulfoxide.

Akinci B, Sankella S, Gilpin C, Ozono K, Garg A, Agarwal AK.

Cold Spring Harb Mol Case Stud. 2017 Jan;3(1):a001339. doi: 10.1101/mcs.a001339.


Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project.

Zignol M, Dean AS, Alikhanova N, Andres S, Cabibbe AM, Cirillo DM, Dadu A, Dreyer A, Driesen M, Gilpin C, Hasan R, Hasan Z, Hoffner S, Husain A, Hussain A, Ismail N, Kamal M, Mansjö M, Mvusi L, Niemann S, Omar SV, Qadeer E, Rigouts L, Ruesch-Gerdes S, Schito M, Seyfaddinova M, Skrahina A, Tahseen S, Wells WA, Mukadi YD, Kimerling M, Floyd K, Weyer K, Raviglione MC.

Lancet Infect Dis. 2016 Oct;16(10):1185-1192. doi: 10.1016/S1473-3099(16)30190-6. Epub 2016 Jul 7.


Implementation of HIV and Tuberculosis Diagnostics: The Importance of Context.

Dominique JK, Ortiz-Osorno AA, Fitzgibbon J, Gnanashanmugam D, Gilpin C, Tucker T, Peel S, Peter T, Kim P, Smith S.

Clin Infect Dis. 2015 Oct 15;61Suppl 3:S119-25. doi: 10.1093/cid/civ552.


Management of latent Mycobacterium tuberculosis infection: WHO guidelines for low tuberculosis burden countries.

Getahun H, Matteelli A, Abubakar I, Aziz MA, Baddeley A, Barreira D, Den Boon S, Borroto Gutierrez SM, Bruchfeld J, Burhan E, Cavalcante S, Cedillos R, Chaisson R, Chee CB, Chesire L, Corbett E, Dara M, Denholm J, de Vries G, Falzon D, Ford N, Gale-Rowe M, Gilpin C, Girardi E, Go UY, Govindasamy D, D Grant A, Grzemska M, Harris R, Horsburgh CR Jr, Ismayilov A, Jaramillo E, Kik S, Kranzer K, Lienhardt C, LoBue P, Lönnroth K, Marks G, Menzies D, Migliori GB, Mosca D, Mukadi YD, Mwinga A, Nelson L, Nishikiori N, Oordt-Speets A, Rangaka MX, Reis A, Rotz L, Sandgren A, Sañé Schepisi M, Schünemann HJ, Sharma SK, Sotgiu G, Stagg HR, Sterling TR, Tayeb T, Uplekar M, van der Werf MJ, Vandevelde W, van Kessel F, van't Hoog A, Varma JK, Vezhnina N, Voniatis C, Vonk Noordegraaf-Schouten M, Weil D, Weyer K, Wilkinson RJ, Yoshiyama T, Zellweger JP, Raviglione M.

Eur Respir J. 2015 Dec;46(6):1563-76. doi: 10.1183/13993003.01245-2015. Epub 2015 Sep 24. Review.


WHO's new end TB strategy.

Uplekar M, Weil D, Lonnroth K, Jaramillo E, Lienhardt C, Dias HM, Falzon D, Floyd K, Gargioni G, Getahun H, Gilpin C, Glaziou P, Grzemska M, Mirzayev F, Nakatani H, Raviglione M; for WHO's Global TB Programme.

Lancet. 2015 May 2;385(9979):1799-1801. doi: 10.1016/S0140-6736(15)60570-0. Epub 2015 Mar 24. No abstract available.


Defining the needs for next generation assays for tuberculosis.

Denkinger CM, Kik SV, Cirillo DM, Casenghi M, Shinnick T, Weyer K, Gilpin C, Boehme CC, Schito M, Kimerling M, Pai M.

J Infect Dis. 2015 Apr 1;211 Suppl 2:S29-38. doi: 10.1093/infdis/jiu821. Review.


Practical biosafety in the tuberculosis laboratory: containment at the source is what truly counts.

van Soolingen D, Wisselink HJ, Lumb R, Anthony R, van der Zanden A, Gilpin C.

Int J Tuberc Lung Dis. 2014 Aug;18(8):885-9. doi: 10.5588/ijtld.13.0629.


Multicenter feasibility study to assess external quality assessment panels for Xpert MTB/RIF assay in South Africa.

Scott L, Albert H, Gilpin C, Alexander H, DeGruy K, Stevens W.

J Clin Microbiol. 2014 Jul;52(7):2493-9. doi: 10.1128/JCM.03533-13. Epub 2014 Apr 30.


Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type.

Witkowski L, Carrot-Zhang J, Albrecht S, Fahiminiya S, Hamel N, Tomiak E, Grynspan D, Saloustros E, Nadaf J, Rivera B, Gilpin C, Castellsagué E, Silva-Smith R, Plourde F, Wu M, Saskin A, Arseneault M, Karabakhtsian RG, Reilly EA, Ueland FR, Margiolaki A, Pavlakis K, Castellino SM, Lamovec J, Mackay HJ, Roth LM, Ulbright TM, Bender TA, Georgoulias V, Longy M, Berchuck A, Tischkowitz M, Nagel I, Siebert R, Stewart CJ, Arseneau J, McCluggage WG, Clarke BA, Riazalhosseini Y, Hasselblatt M, Majewski J, Foulkes WD.

Nat Genet. 2014 May;46(5):438-43. doi: 10.1038/ng.2931. Epub 2014 Mar 23.


Reflex testing for Lynch syndrome: if we build it, will they come? Lessons learned from the uptake of clinical genetics services by individuals with newly diagnosed colorectal cancer (CRC).

Tomiak E, Samson A, Spector N, Mackey M, Gilpin C, Smith E, Jonker D, Allanson J, Asmis T.

Fam Cancer. 2014 Mar;13(1):75-82. doi: 10.1007/s10689-013-9677-0.


Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells.

Raetz M, Hwang SH, Wilhelm CL, Kirkland D, Benson A, Sturge CR, Mirpuri J, Vaishnava S, Hou B, Defranco AL, Gilpin CJ, Hooper LV, Yarovinsky F.

Nat Immunol. 2013 Feb;14(2):136-42. doi: 10.1038/ni.2508. Epub 2012 Dec 23.


Rapid molecular TB diagnosis: evidence, policy making and global implementation of Xpert MTB/RIF.

Weyer K, Mirzayev F, Migliori GB, Van Gemert W, D'Ambrosio L, Zignol M, Floyd K, Centis R, Cirillo DM, Tortoli E, Gilpin C, de Dieu Iragena J, Falzon D, Raviglione M.

Eur Respir J. 2013 Jul;42(1):252-71. doi: 10.1183/09031936.00157212. Epub 2012 Nov 22. Review.


Type III effector VopC mediates invasion for Vibrio species.

Zhang L, Krachler AM, Broberg CA, Li Y, Mirzaei H, Gilpin CJ, Orth K.

Cell Rep. 2012 May 31;1(5):453-60. doi: 10.1016/j.celrep.2012.04.004. Epub 2012 May 3.


Global laboratory initiative tool for a stepwise process towards tuberculosis laboratory accreditation.

Datema TA, Oskam L, Engelberts MF, van Beers SM, Shinnick TM, Baker M, Ridderhof JC, Scholten J, van Deun A, Gilpin C, Klatser PR.

Int J Tuberc Lung Dis. 2012 May;16(5):704-5. doi: 10.5588/ijtld.11.0701. No abstract available.


Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis.

He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, Korsmeyer S, Packer M, May HI, Hill JA, Virgin HW, Gilpin C, Xiao G, Bassel-Duby R, Scherer PE, Levine B.

Nature. 2012 Jan 18;481(7382):511-5. doi: 10.1038/nature10758. Erratum in: Nature. 2013 Nov 7:503(7474):146.


Image-based genome-wide siRNA screen identifies selective autophagy factors.

Orvedahl A, Sumpter R Jr, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, Xie Y, Levine B.

Nature. 2011 Dec 1;480(7375):113-7. doi: 10.1038/nature10546.


RhoA-inhibiting NSAIDs promote axonal myelination after spinal cord injury.

Xing B, Li H, Wang H, Mukhopadhyay D, Fisher D, Gilpin CJ, Li S.

Exp Neurol. 2011 Oct;231(2):247-60. doi: 10.1016/j.expneurol.2011.06.018. Epub 2011 Jul 14.


Pharmaceuticals and related drugs.

Gilpin RK, Gilpin CS.

Anal Chem. 2011 Jun 15;83(12):4489-507. doi: 10.1021/ac2008674. Epub 2011 Apr 29. Review. No abstract available.


Exploring TB-Related Knowledge, Attitude, Behaviour, and Practice among Migrant Workers in Tajikistan.

Gilpin C, de Colombani P, Hasanova S, Sirodjiddinova U.

Tuberc Res Treat. 2011;2011:548617. doi: 10.1155/2011/548617. Epub 2012 Jan 19.


Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance.

Jia K, Thomas C, Akbar M, Sun Q, Adams-Huet B, Gilpin C, Levine B.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14564-9. doi: 10.1073/pnas.0813319106. Epub 2009 Aug 10.


Investigation and diagnosis of nontuberculous mycobacteriosis in a captive herd of aoudad (Ammotragus lervia).

Portas TJ, Bryant BR, Jones SL, Humphreys K, Gilpin CM, Rose KA.

J Zoo Wildl Med. 2009 Jun;40(2):306-15.


Pharmaceuticals and related drugs.

Gilpin RK, Gilpin CS.

Anal Chem. 2009 Jun 15;81(12):4679-94. doi: 10.1021/ac900804d. Review. No abstract available.


Vibrio parahaemolyticus orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and then cell lysis.

Burdette DL, Yarbrough ML, Orvedahl A, Gilpin CJ, Orth K.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12497-502. doi: 10.1073/pnas.0802773105. Epub 2008 Aug 19.


Comparison of methods for processing drinking water samples for the isolation of Mycobacterium avium and Mycobacterium intracellulare.

Thomson R, Carter R, Gilpin C, Coulter C, Hargreaves M.

Appl Environ Microbiol. 2008 May;74(10):3094-8. doi: 10.1128/AEM.02009-07. Epub 2008 Mar 21.


Evidence of primary transmission of multidrug-resistant tuberculosis in the Western Province of Papua New Guinea.

Gilpin CM, Simpson G, Vincent S, O'Brien TP, Knight TA, Globan M, Coulter C, Konstantinos A.

Med J Aust. 2008 Feb 4;188(3):148-52.


Genetic services for hereditary breast/ovarian and colorectal cancers - physicians' awareness, use and satisfaction.

Carroll JC, Cappelli M, Miller F, Wilson BJ, Grunfeld E, Peeters C, Hunter AG, Gilpin C, Prakash P.

Community Genet. 2008;11(1):43-51. doi: 10.1159/000111639. Epub 2008 Jan 15.


Ziehl-Neelsen staining: strong red on weak blue, or weak red under strong blue?

Angra P, Becx-Bleumink M, Gilpin C, Joloba M, Jost K, Kam KM, Kim SJ, Lumb R, Mitarai S, Ramsay A, Ridderhof J, Rieder HL, Selvakumar N, van Beers S, van Cleeff M, Van Deun A, Vincent V.

Int J Tuberc Lung Dis. 2007 Nov;11(11):1160-1. No abstract available.


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