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Items: 1 to 50 of 199

1.

Daptomycin resistance and tolerance due to loss-of-function in Staphylococcus aureus dsp1 and asp23.

Barros EM, Martin MJ, Selleck EM, Lebreton F, Sampaio JLM, Gilmore MS.

Antimicrob Agents Chemother. 2018 Nov 5. pii: AAC.01542-18. doi: 10.1128/AAC.01542-18. [Epub ahead of print]

PMID:
30397055
2.

Molecular basis for the emergence of a new hospital endemic tigecycline-resistant Enterococcus faecalis ST103 lineage.

Dabul ANG, Avaca-Crusca JS, Navais RB, Merlo TP, Van Tyne D, Gilmore MS, Camargo ILBDC.

Infect Genet Evol. 2018 Oct 25;67:23-32. doi: 10.1016/j.meegid.2018.10.018. [Epub ahead of print]

PMID:
30393188
3.

Resolution of fluoroquinolone-resistant Escherichia coli keratitis with a PROSE device for enhanced targeted antibiotic delivery.

Zhai H, Bispo PJM, Kobashi H, Jacobs DS, Gilmore MS, Ciolino JB.

Am J Ophthalmol Case Rep. 2018 Sep 12;12:73-75. doi: 10.1016/j.ajoc.2018.09.006. eCollection 2018 Dec.

4.

Long-Term Colonization Dynamics of Enterococcus faecalis in Implanted Devices in Research Macaques.

Lieberman MT, Van Tyne D, Dzink-Fox J, Ma EJ, Gilmore MS, Fox JG.

Appl Environ Microbiol. 2018 Aug 31;84(18). pii: e01336-18. doi: 10.1128/AEM.01336-18. Print 2018 Sep 15.

PMID:
30006402
5.

Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin-resistant Staphylococcus aureus.

Johnston T, Van Tyne D, Chen RF, Fawzi NL, Kwon B, Kelso MJ, Gilmore MS, Mylonakis E.

Sci Rep. 2018 May 4;8(1):7062. doi: 10.1038/s41598-018-25571-w.

6.

A new class of synthetic retinoid antibiotics effective against bacterial persisters.

Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E.

Nature. 2018 Apr 5;556(7699):103-107. doi: 10.1038/nature26157. Epub 2018 Mar 28.

PMID:
29590091
7.

Transferable vancomycin resistance in clade B commensal-type Enterococcus faecium.

Lebreton F, Valentino MD, Schaufler K, Earl AM, Cattoir V, Gilmore MS.

J Antimicrob Chemother. 2018 Jun 1;73(6):1479-1486. doi: 10.1093/jac/dky039.

PMID:
29462403
8.

Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium.

Zhang S, Lebreton F, Mansfield MJ, Miyashita SI, Zhang J, Schwartzman JA, Tao L, Masuyer G, Martínez-Carranza M, Stenmark P, Gilmore MS, Doxey AC, Dong M.

Cell Host Microbe. 2018 Feb 14;23(2):169-176.e6. doi: 10.1016/j.chom.2017.12.018. Epub 2018 Jan 27.

PMID:
29396040
9.

Rapid Detection and Identification of Uveitis Pathogens by Qualitative Multiplex Real-Time PCR.

Bispo PJM, Davoudi S, Sahm ML, Ren A, Miller J, Romano J, Sobrin L, Gilmore MS.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):582-589. doi: 10.1167/iovs.17-22597.

10.

Neither non-toxigenic Staphylococcus aureus nor commensal S. epidermidi activates NLRP3 inflammasomes in human conjunctival goblet cells.

Li D, Hodges RR, Bispo P, Gilmore MS, Gregory-Ksander M, Dartt DA.

BMJ Open Ophthalmol. 2017 Nov 16;2(1):e000101. doi: 10.1136/bmjophth-2017-000101. eCollection 2017.

11.

Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.

Keohane CE, Steele AD, Fetzer C, Khowsathit J, Van Tyne D, Moynié L, Gilmore MS, Karanicolas J, Sieber SA, Wuest WM.

J Am Chem Soc. 2018 Feb 7;140(5):1774-1782. doi: 10.1021/jacs.7b11212. Epub 2018 Jan 24.

PMID:
29300464
12.

Identification of a Functionally Unique Family of Penicillin-Binding Proteins.

Welsh MA, Taguchi A, Schaefer K, Van Tyne D, Lebreton F, Gilmore MS, Kahne D, Walker S.

J Am Chem Soc. 2017 Dec 13;139(49):17727-17730. doi: 10.1021/jacs.7b10170. Epub 2017 Nov 30.

PMID:
29182854
13.

Resistance in In Vitro Selected Tigecycline-Resistant Methicillin-Resistant Staphylococcus aureus Sequence Type 5 Is Driven by Mutations in mepR and mepA Genes.

Dabul ANG, Avaca-Crusca JS, Van Tyne D, Gilmore MS, Camargo ILBC.

Microb Drug Resist. 2018 Jun;24(5):519-526. doi: 10.1089/mdr.2017.0279. Epub 2017 Oct 17.

PMID:
29039719
14.

Genome-wide screen for genes involved in eDNA release during biofilm formation by Staphylococcus aureus.

DeFrancesco AS, Masloboeva N, Syed AK, DeLoughery A, Bradshaw N, Li GW, Gilmore MS, Walker S, Losick R.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5969-E5978. doi: 10.1073/pnas.1704544114. Epub 2017 Jul 3.

15.

Co-infecting microorganisms dramatically alter pathogen gene essentiality during polymicrobial infection.

Ibberson CB, Stacy A, Fleming D, Dees JL, Rumbaugh K, Gilmore MS, Whiteley M.

Nat Microbiol. 2017 May 30;2:17079. doi: 10.1038/nmicrobiol.2017.79.

16.

Tracing the Enterococci from Paleozoic Origins to the Hospital.

Lebreton F, Manson AL, Saavedra JT, Straub TJ, Earl AM, Gilmore MS.

Cell. 2017 May 18;169(5):849-861.e13. doi: 10.1016/j.cell.2017.04.027. Epub 2017 May 11.

17.

Mapping Transposon Insertions in Bacterial Genomes by Arbitrarily Primed PCR.

Saavedra JT, Schwartzman JA, Gilmore MS.

Curr Protoc Mol Biol. 2017 Apr 3;118:15.15.1-15.15.15. doi: 10.1002/cpmb.38.

18.

Raising the Alarmone: Within-Host Evolution of Antibiotic-Tolerant Enterococcus faecium.

Van Tyne D, Gilmore MS.

MBio. 2017 Feb 21;8(1). pii: e00066-17. doi: 10.1128/mBio.00066-17.

19.

Characterization of Multi-Drug Resistant Enterococcus faecalis Isolated from Cephalic Recording Chambers in Research Macaques (Macaca spp.).

Woods SE, Lieberman MT, Lebreton F, Trowel E, de la Fuente-Núñez C, Dzink-Fox J, Gilmore MS, Fox JG.

PLoS One. 2017 Jan 12;12(1):e0169293. doi: 10.1371/journal.pone.0169293. eCollection 2017.

20.

High-Quality Draft Genome Sequence of the Multidrug-Resistant Clinical Isolate Enterococcus faecium VRE16.

de Mello SS, Van Tyne D, Dabul AN, Gilmore MS, Camargo IL.

Genome Announc. 2016 Sep 22;4(5). pii: e00992-16. doi: 10.1128/genomeA.00992-16.

21.

Novel Phagocytosis-Resistant Extended-Spectrum β-Lactamase-Producing Escherichia coli From Keratitis.

Van Tyne D, Ciolino JB, Wang J, Durand ML, Gilmore MS.

JAMA Ophthalmol. 2016 Nov 1;134(11):1306-1309. doi: 10.1001/jamaophthalmol.2016.3283.

22.

Oxygen as a Virulence Determinant in Polymicrobial Infections.

Selleck EM, Gilmore MS.

MBio. 2016 Aug 16;7(4). pii: e01249-16. doi: 10.1128/mBio.01249-16.

23.

Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon Libraries.

Rajagopal M, Martin MJ, Santiago M, Lee W, Kos VN, Meredith T, Gilmore MS, Walker S.

MBio. 2016 Aug 16;7(4). pii: e00950-16. doi: 10.1128/mBio.00950-16.

24.

Homologous Recombination within Large Chromosomal Regions Facilitates Acquisition of β-Lactam and Vancomycin Resistance in Enterococcus faecium.

García-Solache M, Lebreton F, McLaughlin RE, Whiteaker JD, Gilmore MS, Rice LB.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5777-86. doi: 10.1128/AAC.00488-16. Print 2016 Oct.

25.

A lysin to kill.

Gaca AO, Gilmore MS.

Elife. 2016 Apr 27;5. pii: e16111. doi: 10.7554/eLife.16111.

26.
27.

Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection.

Wilde AD, Snyder DJ, Putnam NE, Valentino MD, Hammer ND, Lonergan ZR, Hinger SA, Aysanoa EE, Blanchard C, Dunman PM, Wasserman GA, Chen J, Shopsin B, Gilmore MS, Skaar EP, Cassat JE.

PLoS Pathog. 2015 Dec 18;11(12):e1005341. doi: 10.1371/journal.ppat.1005341. eCollection 2015 Dec.

28.

Staphylococcus aureus and its Bearing on Ophthalmic Disease.

Sadaka A, Durand ML, Sisk R, Gilmore MS.

Ocul Immunol Inflamm. 2017 Feb;25(1):111-121. doi: 10.3109/09273948.2015.1075559. Epub 2015 Dec 17. Review.

PMID:
26679534
29.

Impact of Antibiotic Use on the Evolution of Enterococcus faecium.

Wurster JI, Saavedra JT, Gilmore MS.

J Infect Dis. 2016 Jun 15;213(12):1862-5. doi: 10.1093/infdis/jiv598. Epub 2015 Dec 15. No abstract available.

30.

Fungal Infections After Boston Type 1 Keratoprosthesis Implantation: Literature Review and In Vitro Antifungal Activity of Hypochlorous Acid.

Odorcic S, Haas W, Gilmore MS, Dohlman CH.

Cornea. 2015 Dec;34(12):1599-605. doi: 10.1097/ICO.0000000000000639. Review.

31.

Pheromone killing of multidrug-resistant Enterococcus faecalis V583 by native commensal strains.

Gilmore MS, Rauch M, Ramsey MM, Himes PR, Varahan S, Manson JM, Lebreton F, Hancock LE.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7273-8. doi: 10.1073/pnas.1500553112. Epub 2015 May 26.

32.

A CRISPR View of Cleavage.

Weinberger AD, Gilmore MS.

Cell. 2015 May 21;161(5):964-966. doi: 10.1016/j.cell.2015.05.003.

33.

Complete Genome Sequence of Linezolid-Susceptible Staphylococcus haemolyticus Sh29/312/L2, a Clonal Derivative of a Linezolid-Resistant Clinical Strain.

de Almeida LM, Pires C, Cerdeira LT, de Oliveira TG, McCulloch JA, Perez-Chaparro PJ, Sacramento AG, Brito AC, da Silva JL, de Araújo MR, Lincopan N, Martin MJ, Gilmore MS, Mamizuka EM.

Genome Announc. 2015 May 21;3(3). pii: e00494-15. doi: 10.1128/genomeA.00494-15.

34.

Novel model of innate immunity in corneal infection.

Rajaiya J, Zhou X, Barequet I, Gilmore MS, Chodosh J.

In Vitro Cell Dev Biol Anim. 2015 Sep;51(8):827-34. doi: 10.1007/s11626-015-9910-2. Epub 2015 May 15.

35.

A new platform for ultra-high density Staphylococcus aureus transposon libraries.

Santiago M, Matano LM, Moussa SH, Gilmore MS, Walker S, Meredith TC.

BMC Genomics. 2015 Mar 29;16:252. doi: 10.1186/s12864-015-1361-3.

36.

Biofilms in infections of the eye.

Bispo PJ, Haas W, Gilmore MS.

Pathogens. 2015 Mar 23;4(1):111-36. doi: 10.3390/pathogens4010111. Review.

37.

Mutations in pneumococcal cpsE generated via in vitro serial passaging reveal a potential mechanism of reduced encapsulation utilized by a conjunctival isolate.

Shainheit MG, Valentino MD, Gilmore MS, Camilli A.

J Bacteriol. 2015 May;197(10):1781-91. doi: 10.1128/JB.02602-14. Epub 2015 Mar 16.

38.

A genomic virulence reference map of Enterococcus faecalis reveals an important contribution of phage03-like elements in nosocomial genetic lineages to pathogenicity in a Caenorhabditis elegans infection model.

La Rosa SL, Snipen LG, Murray BE, Willems RJ, Gilmore MS, Diep DB, Nes IF, Brede DA.

Infect Immun. 2015 May;83(5):2156-67. doi: 10.1128/IAI.02801-14. Epub 2015 Mar 16.

39.

Virulence Plasmids of Nonsporulating Gram-Positive Pathogens.

Van Tyne D, Gilmore MS.

Microbiol Spectr. 2014 Oct;2(5). doi: 10.1128/microbiolspec.PLAS-0002-2013. Review.

40.

Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster.

Valentino MD, McGuire AM, Rosch JW, Bispo PJ, Burnham C, Sanfilippo CM, Carter RA, Zegans ME, Beall B, Earl AM, Tuomanen EI, Morris TW, Haas W, Gilmore MS.

Nat Commun. 2014 Nov 12;5:5411. doi: 10.1038/ncomms6411.

41.

In vitro and in vivo models of Staphylococcus aureus endophthalmitis implicate specific nutrients in ocular infection.

Sadaka A, Palmer K, Suzuki T, Gilmore MS.

PLoS One. 2014 Oct 23;9(10):e110872. doi: 10.1371/journal.pone.0110872. eCollection 2014.

42.

A delicate balance: maintaining mutualism to prevent disease.

Van Tyne D, Gilmore MS.

Cell Host Microbe. 2014 Oct 8;16(4):425-7. doi: 10.1016/j.chom.2014.09.019.

43.

An ABC transporter is required for secretion of peptide sex pheromones in Enterococcus faecalis.

Varahan S, Harms N, Gilmore MS, Tomich JM, Hancock LE.

MBio. 2014 Sep 23;5(5):e01726-14. doi: 10.1128/mBio.01726-14.

44.

Transcriptomic response of Enterococcus faecalis V583 to low hydrogen peroxide levels.

Yan X, Budin-Verneuil A, Verneuil N, Gilmore MS, Artigaud S, Auffray Y, Pichereau V.

Curr Microbiol. 2015 Feb;70(2):156-68. doi: 10.1007/s00284-014-0691-8. Epub 2014 Sep 23.

PMID:
25245959
45.

Genes contributing to Staphylococcus aureus fitness in abscess- and infection-related ecologies.

Valentino MD, Foulston L, Sadaka A, Kos VN, Villet RA, Santa Maria J Jr, Lazinski DW, Camilli A, Walker S, Hooper DC, Gilmore MS.

MBio. 2014 Sep 2;5(5):e01729-14. doi: 10.1128/mBio.01729-14.

46.

Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids.

Santa Maria JP Jr, Sadaka A, Moussa SH, Brown S, Zhang YJ, Rubin EJ, Gilmore MS, Walker S.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12510-5. doi: 10.1073/pnas.1404099111. Epub 2014 Aug 7.

47.

Friend turned foe: evolution of enterococcal virulence and antibiotic resistance.

Van Tyne D, Gilmore MS.

Annu Rev Microbiol. 2014;68:337-56. doi: 10.1146/annurev-micro-091213-113003. Epub 2014 Jun 18. Review.

48.

Enterococcus Diversity, Origins in Nature, and Gut Colonization.

Lebreton F, Willems RJL, Gilmore MS.

In: Gilmore MS, Clewell DB, Ike Y, Shankar N, editors. Enterococci: From Commensals to Leading Causes of Drug Resistant Infection [Internet]. Boston: Massachusetts Eye and Ear Infirmary; 2014-.
2014 Feb 2.

49.

Enterococcal Genomics.

Palmer KL, van Schaik W, Willems RJL, Gilmore MS.

In: Gilmore MS, Clewell DB, Ike Y, Shankar N, editors. Enterococci: From Commensals to Leading Causes of Drug Resistant Infection [Internet]. Boston: Massachusetts Eye and Ear Infirmary; 2014-.
2014 Feb 8.

50.

Transcriptional response of Enterococcus faecalis to sunlight.

Sassoubre LM, Ramsey MM, Gilmore MS, Boehm AB.

J Photochem Photobiol B. 2014 Jan 5;130:349-56. doi: 10.1016/j.jphotobiol.2013.12.013. Epub 2013 Dec 30.

PMID:
24434819

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