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Association of Changes in Air Quality With Incident Asthma in Children in California, 1993-2014.

Garcia E, Berhane KT, Islam T, McConnell R, Urman R, Chen Z, Gilliland FD.

JAMA. 2019 May 21;321(19):1906-1915. doi: 10.1001/jama.2019.5357.


Elucidation of causal direction between asthma and obesity: a bi-directional Mendelian randomization study.

Xu S, Gilliland FD, Conti DV.

Int J Epidemiol. 2019 Apr 21. pii: dyz070. doi: 10.1093/ije/dyz070. [Epub ahead of print]


High intake of dietary fructose in overweight/obese teenagers associated with depletion of Eubacterium and Streptococcus in gut microbiome.

Jones RB, Alderete TL, Kim JS, Millstein J, Gilliland FD, Goran MI.

Gut Microbes. 2019 Apr 16:1-8. doi: 10.1080/19490976.2019.1592420. [Epub ahead of print]


Understanding the importance of key risk factors in predicting chronic bronchitic symptoms using a machine learning approach.

Deng H, Urman R, Gilliland FD, Eckel SP.

BMC Med Res Methodol. 2019 Mar 29;19(1):70. doi: 10.1186/s12874-019-0708-x.


Perfluoroalkyl substances, metabolomic profiling, and alterations in glucose homeostasis among overweight and obese Hispanic children: A proof-of-concept analysis.

Alderete TL, Jin R, Walker DI, Valvi D, Chen Z, Jones DP, Peng C, Gilliland FD, Berhane K, Conti DV, Goran MI, Chatzi L.

Environ Int. 2019 May;126:445-453. doi: 10.1016/j.envint.2019.02.047. Epub 2019 Mar 4.


Within-subject effects of environmental and social stressors on pre- and post-partum obesity-related biobehavioral responses in low-income Hispanic women: protocol of an intensive longitudinal study.

O'Connor SG, Habre R, Bastain TM, Toledo-Corral CM, Gilliland FD, Eckel SP, Cabison J, Naya CH, Farzan SF, Chu D, Chavez TA, Breton CV, Dunton GF.

BMC Public Health. 2019 Feb 28;19(1):253. doi: 10.1186/s12889-019-6583-x.


Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.

Galle-Treger L, Sankaranarayanan I, Hurrell BP, Howard E, Lo R, Maazi H, Lewis G, Banie H, Epstein AL, Hu P, Rehan VK, Gilliland FD, Allayee H, Soroosh P, Sharpe AH, Akbari O.

Nat Commun. 2019 Feb 12;10(1):713. doi: 10.1038/s41467-019-08449-x.


Applying Multivariate Segmentation Methods to Human Activity Recognition From Wearable Sensors' Data.

Li K, Habre R, Deng H, Urman R, Morrison J, Gilliland FD, Ambite JL, Stripelis D, Chiang YY, Lin Y, Bui AA, King C, Hosseini A, Vliet EV, Sarrafzadeh M, Eckel SP.

JMIR Mhealth Uhealth. 2019 Feb 7;7(2):e11201. doi: 10.2196/11201.


Association of Prenatal Exposure to Ambient and Traffic-Related Air Pollution With Newborn Thyroid Function: Findings From the Children's Health Study.

Howe CG, Eckel SP, Habre R, Girguis MS, Gao L, Lurmann FW, Gilliland FD, Breton CV.

JAMA Netw Open. 2018 Sep 7;1(5):e182172. doi: 10.1001/jamanetworkopen.2018.2172.


Regional and traffic-related air pollutants are associated with higher consumption of fast food and trans fat among adolescents.

Chen Z, Herting MM, Chatzi L, Belcher BR, Alderete TL, McConnell R, Gilliland FD.

Am J Clin Nutr. 2019 Jan 1;109(1):99-108. doi: 10.1093/ajcn/nqy232.


Gene Coexpression Networks in Whole Blood Implicate Multiple Interrelated Molecular Pathways in Obesity in People with Asthma.

Croteau-Chonka DC, Chen Z, Barnes KC, Barraza-Villarreal A, Celedón JC, Gauderman WJ, Gilliland FD, Krishnan JA, Liu AH, London SJ, Martinez FD, Millstein J, Naureckas ET, Nicolae DL, White SR, Ober C, Weiss ST, Raby BA.

Obesity (Silver Spring). 2018 Dec;26(12):1938-1948. doi: 10.1002/oby.22341. Epub 2018 Oct 25.


Ambient and Traffic-Related Air Pollution Exposures as Novel Risk Factors for Metabolic Dysfunction and Type 2 Diabetes.

Alderete TL, Chen Z, Toledo-Corral CM, Contreras ZA, Kim JS, Habre R, Chatzi L, Bastain T, Breton CV, Gilliland FD.

Curr Epidemiol Rep. 2018 Jun;5(2):79-91. doi: 10.1007/s40471-018-0140-5. Epub 2018 Apr 10.


Longitudinal associations of in utero and early life near-roadway air pollution with trajectories of childhood body mass index.

Kim JS, Alderete TL, Chen Z, Lurmann F, Rappaport E, Habre R, Berhane K, Gilliland FD.

Environ Health. 2018 Sep 14;17(1):64. doi: 10.1186/s12940-018-0409-7.


Single-Cell Digital Lysates Generated by Phase-Switch Microfluidic Device Reveal Transcriptome Perturbation of Cell Cycle.

Chen Y, Millstein J, Liu Y, Chen GY, Chen X, Stucky A, Qu C, Fan JB, Chang X, Soleimany A, Wang K, Zhong J, Liu J, Gilliland FD, Li Z, Zhang X, Zhong JF.

ACS Nano. 2018 May 22;12(5):4687-4694. doi: 10.1021/acsnano.8b01272. Epub 2018 Apr 18.


Gene Promoter Hypermethylation Detected in Sputum Predicts FEV1 Decline and All-Cause Mortality in Smokers.

Leng S, Diergaarde B, Picchi MA, Wilson DO, Gilliland FD, Yuan JM, Siegfried JM, Belinsky SA.

Am J Respir Crit Care Med. 2018 Jul 15;198(2):187-196. doi: 10.1164/rccm.201708-1659OC.


Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus.

Kothari PH, Qiu W, Croteau-Chonka DC, Martinez FD, Liu AH, Lemanske RF Jr, Ober C, Krishnan JA, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, White SR, Naureckas ET, Millstein J, Gauderman WJ, Gilliland FD, Carey VJ, Weiss ST, Raby BA; Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium.

J Allergy Clin Immunol. 2018 Jun;141(6):2282-2286.e6. doi: 10.1016/j.jaci.2017.11.057. Epub 2018 Jan 31. No abstract available.


Exposure to traffic-related air pollution and the composition of the gut microbiota in overweight and obese adolescents.

Alderete TL, Jones RB, Chen Z, Kim JS, Habre R, Lurmann F, Gilliland FD, Goran MI.

Environ Res. 2018 Feb;161:472-478. doi: 10.1016/j.envres.2017.11.046.


Effect of inhaled allergens and air pollutants on childhood rhinitis development.

Zhou H, Li XI, Kim JH, Salam MT, Kim HB, McConnell RS, Habre R, Bastain T, Farzan SF, Johnston J, Gilliland FD.

Ann Allergy Asthma Immunol. 2018 Feb;120(2):212-214. doi: 10.1016/j.anai.2017.10.036. Epub 2017 Dec 6. No abstract available.


Epigenetic regulation of AXL and risk of childhood asthma symptoms.

Gao L, Millstein J, Siegmund KD, Dubeau L, Maguire R, Gilliland FD, Murphy SK, Hoyo C, Breton CV.

Clin Epigenetics. 2017 Nov 7;9:121. doi: 10.1186/s13148-017-0421-8. eCollection 2017.


Dietary nutrients associated with preservation of lung function in Hispanic and non-Hispanic white smokers from New Mexico.

Leng S, Picchi MA, Tesfaigzi Y, Wu G, Gauderman WJ, Xu F, Gilliland FD, Belinsky SA.

Int J Chron Obstruct Pulmon Dis. 2017 Oct 30;12:3171-3181. doi: 10.2147/COPD.S142237. eCollection 2017.


Dietary Nutrient Intake, Ethnicity, and Epigenetic Silencing of Lung Cancer Genes Detected in Sputum in New Mexican Smokers.

Leng S, Picchi MA, Kang H, Wu G, Filipczak PT, Juri DE, Zhang X, Gauderman WJ, Gilliland FD, Belinsky SA.

Cancer Prev Res (Phila). 2018 Feb;11(2):93-102. doi: 10.1158/1940-6207.CAPR-17-0196. Epub 2017 Nov 8.


Prenatal traffic-related air pollution exposures, cord blood adipokines and infant weight.

Alderete TL, Song AY, Bastain T, Habre R, Toledo-Corral CM, Salam MT, Lurmann F, Gilliland FD, Breton CV.

Pediatr Obes. 2018 Jun;13(6):348-356. doi: 10.1111/ijpo.12248. Epub 2017 Nov 3.


Genetic and epigenetic susceptibility of airway inflammation to PM2.5 in school children: new insights from quantile regression.

Zhang Y, Salam MT, Berhane K, Eckel SP, Rappaport EB, Linn WS, Habre R, Bastain TM, Gilliland FD.

Environ Health. 2017 Aug 18;16(1):88. doi: 10.1186/s12940-017-0285-6.


Constrained Mixed-Effect Models with Ensemble Learning for Prediction of Nitrogen Oxides Concentrations at High Spatiotemporal Resolution.

Li L, Lurmann F, Habre R, Urman R, Rappaport E, Ritz B, Chen JC, Gilliland FD, Wu J.

Environ Sci Technol. 2017 Sep 5;51(17):9920-9929. doi: 10.1021/acs.est.7b01864. Epub 2017 Aug 11.


Particulate matter air pollution and liver cancer survival.

Deng H, Eckel SP, Liu L, Lurmann FW, Cockburn MG, Gilliland FD.

Int J Cancer. 2017 Aug 15;141(4):744-749. doi: 10.1002/ijc.30779. Epub 2017 Jun 7.


Longitudinal Associations Between Ambient Air Pollution With Insulin Sensitivity, β-Cell Function, and Adiposity in Los Angeles Latino Children.

Alderete TL, Habre R, Toledo-Corral CM, Berhane K, Chen Z, Lurmann FW, Weigensberg MJ, Goran MI, Gilliland FD.

Diabetes. 2017 Jul;66(7):1789-1796. doi: 10.2337/db16-1416. Epub 2017 Jan 30.


Effects of Childhood Asthma on the Development of Obesity among School-aged Children.

Chen Z, Salam MT, Alderete TL, Habre R, Bastain TM, Berhane K, Gilliland FD.

Am J Respir Crit Care Med. 2017 May 1;195(9):1181-1188. doi: 10.1164/rccm.201608-1691OC.


Effects of air pollution exposure on glucose metabolism in Los Angeles minority children.

Toledo-Corral CM, Alderete TL, Habre R, Berhane K, Lurmann FW, Weigensberg MJ, Goran MI, Gilliland FD.

Pediatr Obes. 2018 Jan;13(1):54-62. doi: 10.1111/ijpo.12188. Epub 2016 Dec 6.


Gene Expression Profiling in Blood Provides Reproducible Molecular Insights into Asthma Control.

Croteau-Chonka DC, Qiu W, Martinez FD, Strunk RC, Lemanske RF Jr, Liu AH, Gilliland FD, Millstein J, Gauderman WJ, Ober C, Krishnan JA, White SR, Naureckas ET, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, Carey VJ, Weiss ST, Raby BA; Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium.

Am J Respir Crit Care Med. 2017 Jan 15;195(2):179-188. doi: 10.1164/rccm.201601-0107OC.


Air pollution affects lung cancer survival.

Eckel SP, Cockburn M, Shu YH, Deng H, Lurmann FW, Liu L, Gilliland FD.

Thorax. 2016 Oct;71(10):891-8. doi: 10.1136/thoraxjnl-2015-207927. Epub 2016 Aug 4.


Ambient Air Pollution Is Associated With the Severity of Coronary Atherosclerosis and Incident Myocardial Infarction in Patients Undergoing Elective Cardiac Evaluation.

Hartiala J, Breton CV, Tang WH, Lurmann F, Hazen SL, Gilliland FD, Allayee H.

J Am Heart Assoc. 2016 Jul 28;5(8). pii: e003947. doi: 10.1161/JAHA.116.003947.


A prospective and retrospective analysis of smoking behavior changes in ever smokers with high risk for lung cancer from New Mexico and Pennsylvania.

Leng S, Weissfeld JL, Picchi MA, Styn MA, Claus ED, Clark VP, Wu G, Thomas CL, Gilliland FD, Yuan J, Siegfried JM, Belinsky SA.

Int J Mol Epidemiol Genet. 2016 Jun 1;7(2):95-104. eCollection 2016.


Prenatal Air Pollution Exposures, DNA Methyl Transferase Genotypes, and Associations with Newborn LINE1 and Alu Methylation and Childhood Blood Pressure and Carotid Intima-Media Thickness in the Children's Health Study.

Breton CV, Yao J, Millstein J, Gao L, Siegmund KD, Mack W, Whitfield-Maxwell L, Lurmann F, Hodis H, Avol E, Gilliland FD.

Environ Health Perspect. 2016 Dec;124(12):1905-1912. Epub 2016 May 24.


Correction: Inducible Nitric Oxide Synthase Promoter Haplotypes and Residential Traffic-Related Air Pollution Jointly Influence Exhaled Nitric Oxide Level in Children.

Salam MT, Lin PC, Eckel SP, Gauderman WJ, Gilliland FD.

PLoS One. 2016 May 9;11(5):e0155567. doi: 10.1371/journal.pone.0155567. eCollection 2016.


Ambient Air Pollutants Have Adverse Effects on Insulin and Glucose Homeostasis in Mexican Americans.

Chen Z, Salam MT, Toledo-Corral C, Watanabe RM, Xiang AH, Buchanan TA, Habre R, Bastain TM, Lurmann F, Wilson JP, Trigo E, Gilliland FD.

Diabetes Care. 2016 Apr;39(4):547-54. doi: 10.2337/dc15-1795. Epub 2016 Feb 11.


Lifetime prevalence of childhood eczema and the effect of indoor environmental factors: Analysis in Hispanic and non-Hispanic white children.

Kim HB, Zhou H, Kim JH, Habre R, Bastain TM, Gilliland FD.

Allergy Asthma Proc. 2016 Jan-Feb;37(1):64-71. doi: 10.2500/aap.2016.37.3913.


Traffic-related air pollution and alveolar nitric oxide in southern California children.

Eckel SP, Zhang Z, Habre R, Rappaport EB, Linn WS, Berhane K, Zhang Y, Bastain TM, Gilliland FD.

Eur Respir J. 2016 May;47(5):1348-56. doi: 10.1183/13993003.01176-2015. Epub 2016 Jan 21.


Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II (Genes-Environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) Studies.

Neophytou AM, White MJ, Oh SS, Thakur N, Galanter JM, Nishimura KK, Pino-Yanes M, Torgerson DG, Gignoux CR, Eng C, Nguyen EA, Hu D, Mak AC, Kumar R, Seibold MA, Davis A, Farber HJ, Meade K, Avila PC, Serebrisky D, Lenoir MA, Brigino-Buenaventura E, Rodriguez-Cintron W, Bibbins-Domingo K, Thyne SM, Williams LK, Sen S, Gilliland FD, Gauderman WJ, Rodriguez-Santana JR, Lurmann F, Balmes JR, Eisen EA, Burchard EG.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1271-80. doi: 10.1164/rccm.201508-1706OC.


Inducible Nitric Oxide Synthase Promoter Haplotypes and Residential Traffic-Related Air Pollution Jointly Influence Exhaled Nitric Oxide Level in Children.

Salam MT, Lin PC, Eckel SP, Gauderman WJ, Gilliland FD.

PLoS One. 2015 Dec 29;10(12):e0145363. doi: 10.1371/journal.pone.0145363. eCollection 2015. Erratum in: PLoS One. 2016;11(5):e0155567.


Exhaled NO: Determinants and Clinical Application in Children With Allergic Airway Disease.

Kim HB, Eckel SP, Kim JH, Gilliland FD.

Allergy Asthma Immunol Res. 2016 Jan;8(1):12-21. doi: 10.4168/aair.2016.8.1.12. Epub 2015 Jul 2. Review.


Correction: Genetic Ancestry and Asthma and Rhinitis Occurrence in Hispanic Children: Findings from the Southern California Children's Health Study.

Salam MT, Avoundjian T, Knight WM, Gilliland FD.

PLoS One. 2015 Sep 25;10(9):e0139397. doi: 10.1371/journal.pone.0139397. eCollection 2015. No abstract available.


Genetic Ancestry and Asthma and Rhinitis Occurrence in Hispanic Children: Findings from the Southern California Children's Health Study.

Salam MT, Avoundjian T, Knight WM, Gilliland FD.

PLoS One. 2015 Aug 11;10(8):e0135384. doi: 10.1371/journal.pone.0135384. eCollection 2015. Erratum in: PLoS One. 2015;10(9):e0139397.


Determinants of Children's Exhaled Nitric Oxide: New Insights from Quantile Regression.

Zhang Y, Berhane K, Eckel SP, Salam MT, Linn WS, Rappaport EB, Bastain TM, Gilliland FD.

PLoS One. 2015 Jul 27;10(7):e0130505. doi: 10.1371/journal.pone.0130505. eCollection 2015.


Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.

Leng S, Wu G, Collins LB, Thomas CL, Tellez CS, Jauregui AR, Picchi MA, Zhang X, Juri DE, Desai D, Amin SG, Crowell RE, Stidley CA, Liu Y, Swenberg JA, Lin Y, Wathelet MG, Gilliland FD, Belinsky SA.

Cancer Res. 2015 Aug 1;75(15):3108-17. doi: 10.1158/0008-5472.CAN-15-0243. Epub 2015 Jul 16.


Does near-roadway air pollution contribute to childhood obesity?

McConnell R, Gilliland FD, Goran M, Allayee H, Hricko A, Mittelman S.

Pediatr Obes. 2016 Feb;11(1):1-3. doi: 10.1111/ijpo.12016. Epub 2015 Mar 27. No abstract available.


15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers.

Leng S, Liu Y, Weissfeld JL, Thomas CL, Han Y, Picchi MA, Edlund CK, Willink RP, Gaither Davis AL, Do KC, Nukui T, Zhang X, Burki EA, Van Den Berg D, Romkes M, Gauderman WJ, Crowell RE, Tesfaigzi Y, Stidley CA, Amos CI, Siegfried JM, Gilliland FD, Belinsky SA.

J Natl Cancer Inst. 2015 Feb 23;107(5). pii: djv035. doi: 10.1093/jnci/djv035.


Chronic effects of air pollution on respiratory health in Southern California children: findings from the Southern California Children's Health Study.

Chen Z, Salam MT, Eckel SP, Breton CV, Gilliland FD.

J Thorac Dis. 2015 Jan;7(1):46-58. doi: 10.3978/j.issn.2072-1439.2014.12.20. Review.


Living near a freeway is associated with lower bone mineral density among Mexican Americans.

Chen Z, Salam MT, Karim R, Toledo-Corral CM, Watanabe RM, Xiang AH, Buchanan TA, Habre R, Bastain TM, Lurmann F, Taher M, Wilson JP, Trigo E, Gilliland FD.

Osteoporos Int. 2015 Jun;26(6):1713-21. doi: 10.1007/s00198-015-3051-z. Epub 2015 Feb 13.


Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma.

Igartua C, Myers RA, Mathias RA, Pino-Yanes M, Eng C, Graves PE, Levin AM, Del-Rio-Navarro BE, Jackson DJ, Livne OE, Rafaels N, Edlund CK, Yang JJ, Huntsman S, Salam MT, Romieu I, Mourad R, Gern JE, Lemanske RF, Wyss A, Hoppin JA, Barnes KC, Burchard EG, Gauderman WJ, Martinez FD, Raby BA, Weiss ST, Williams LK, London SJ, Gilliland FD, Nicolae DL, Ober C.

Nat Commun. 2015 Jan 16;6:5965. doi: 10.1038/ncomms6965.


A longitudinal cohort study of body mass index and childhood exposure to secondhand tobacco smoke and air pollution: the Southern California Children's Health Study.

McConnell R, Shen E, Gilliland FD, Jerrett M, Wolch J, Chang CC, Lurmann F, Berhane K.

Environ Health Perspect. 2015 Apr;123(4):360-6. doi: 10.1289/ehp.1307031. Epub 2014 Nov 12. Erratum in: Environ Health Perspect. 2015 Apr;123(4):A81.

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