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Characterization methods for studying protein adsorption on nano-polystyrene beads.

Contado C, Mehn D, Gilliland D, Calzolai L.

J Chromatogr A. 2019 Jul 19:460383. doi: 10.1016/j.chroma.2019.460383. [Epub ahead of print]


Vial sonication and ultrasonic immersion probe sonication to generate stable dispersions of multiwall carbon nanotubes for physico-chemical characterization and biological testing.

Rio-Echevarria IM, Ponti J, Urbán P, Gilliland D.

Nanotoxicology. 2019 May 20:1-15. doi: 10.1080/17435390.2019.1597203. [Epub ahead of print]


A high throughput imaging database of toxicological effects of nanomaterials tested on HepaRG cells.

Joossens E, Macko P, Palosaari T, Gerloff K, Ojea-Jiménez I, Gilliland D, Novak J, Fortaner Torrent S, Gineste JM, Römer I, Briffa SM, Valsami-Jones E, Lynch I, Whelan M.

Sci Data. 2019 May 2;6(1):46. doi: 10.1038/s41597-019-0053-2.


Review of micro- and nanoplastic contamination in the food chain.

Toussaint B, Raffael B, Angers-Loustau A, Gilliland D, Kestens V, Petrillo M, Rio-Echevarria IM, Van den Eede G.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 May;36(5):639-673. doi: 10.1080/19440049.2019.1583381. Epub 2019 Apr 15. Review.


How can tomorrow's doctors be more caring? A phenomenological investigation.

Gillespie H, Kelly M, Gormley G, King N, Gilliland D, Dornan T.

Med Educ. 2018 Oct;52(10):1052-1063. doi: 10.1111/medu.13684.


Waterborne exposure of adult zebrafish to silver nanoparticles and to ionic silver results in differential silver accumulation and effects at cellular and molecular levels.

Lacave JM, Vicario-Parés U, Bilbao E, Gilliland D, Mura F, Dini L, Cajaraville MP, Orbea A.

Sci Total Environ. 2018 Nov 15;642:1209-1220. doi: 10.1016/j.scitotenv.2018.06.128. Epub 2018 Jun 20.


Rational design of multi-functional gold nanoparticles with controlled biomolecule adsorption: a multi-method approach for in-depth characterization.

Ojea-Jiménez I, Capomaccio R, Osório I, Mehn D, Ceccone G, Hussain R, Siligardi G, Colpo P, Rossi F, Gilliland D, Calzolai L.

Nanoscale. 2018 May 31;10(21):10173-10181. doi: 10.1039/c8nr00973b.


Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines.

Hansjosten I, Rapp J, Reiner L, Vatter R, Fritsch-Decker S, Peravali R, Palosaari T, Joossens E, Gerloff K, Macko P, Whelan M, Gilliland D, Ojea-Jimenez I, Monopoli MP, Rocks L, Garry D, Dawson K, Röttgermann PJF, Murschhauser A, Rädler JO, Tang SVY, Gooden P, Belinga-Desaunay MA, Khan AO, Briffa S, Guggenheim E, Papadiamantis A, Lynch I, Valsami-Jones E, Diabaté S, Weiss C.

Arch Toxicol. 2018 Feb;92(2):633-649. doi: 10.1007/s00204-017-2106-7. Epub 2017 Nov 8.


Physico-chemical properties of manufactured nanomaterials - Characterisation and relevant methods. An outlook based on the OECD Testing Programme.

Rasmussen K, Rauscher H, Mech A, Riego Sintes J, Gilliland D, González M, Kearns P, Moss K, Visser M, Groenewold M, Bleeker EAJ.

Regul Toxicol Pharmacol. 2018 Feb;92:8-28. doi: 10.1016/j.yrtph.2017.10.019. Epub 2017 Oct 23. Review.


Analysis of Vitamin D₂ and Vitamin D₃ in Fortified Milk Powders and Infant and Nutritional Formulas by Liquid Chromatography-Tandem Mass Spectrometry: Single-Laboratory Validation, First Action 2016.05.

Gill BD, Abernethy GA, Green RJ, Indyk HE, Sullivan D, Austad J, Bhandari S, Campos-Gimenez E, Christiansen S, Cruijsen H, DeVries J, Gill B, Gilliland D, Huang M, Kneeteman E, McMahon A, Mindak B, Ofitserova M, Phillips M, Phillips S, Schimpf K, Raffler G, Rimmer K, van Loon W, Yang J.

J AOAC Int. 2017 Jan 1;100(1):298-302. doi: 10.5740/jaoacint.2016_05. No abstract available.


Lysosomal responses to different gold forms (nanoparticles, aqueous, bulk) in mussel digestive cells: a trade-off between the toxicity of the capping agent and form, size and exposure concentration.

Jimeno-Romero A, Izagirre U, Gilliland D, Warley A, Cajaraville MP, Marigómez I, Soto M.

Nanotoxicology. 2017 Jun;11(5):658-670. doi: 10.1080/17435390.2017.1342012.


Influence of different cleaning processes on the surface chemistry of gold nanoparticles.

La Spina R, Spampinato V, Gilliland D, Ojea-Jimenez I, Ceccone G.

Biointerphases. 2017 Jul 27;12(3):031003. doi: 10.1116/1.4994286.


Unifying mechanism for different fibrotic diseases.

Wernig G, Chen SY, Cui L, Van Neste C, Tsai JM, Kambham N, Vogel H, Natkunam Y, Gilliland DG, Nolan G, Weissman IL.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4757-4762. doi: 10.1073/pnas.1621375114. Epub 2017 Apr 19.


Analytical ultracentrifugation for analysis of doxorubicin loaded liposomes.

Mehn D, Iavicoli P, Cabaleiro N, Borgos SE, Caputo F, Geiss O, Calzolai L, Rossi F, Gilliland D.

Int J Pharm. 2017 May 15;523(1):320-326. doi: 10.1016/j.ijpharm.2017.03.046. Epub 2017 Mar 22.


Silver Nanoparticles and Metallic Silver Interfere with the Griess Reaction: Reduction of Azo Dye Formation via a Competing Sandmeyer-Like Reaction.

Kämpfer A, La Spina R, Gilliland D, Valzacchi S, Asturiol D, Stone V, Kinsner-Ovaskainen A.

Chem Res Toxicol. 2017 Apr 17;30(4):1030-1037. doi: 10.1021/acs.chemrestox.6b00280. Epub 2017 Mar 24.


Gold nanoparticles increases UV and thermal stability of human serum albumin.

Capomaccio R, Osório I, Ojea-Jiménez I, Ceccone G, Colpo P, Gilliland D, Hussain R, Siligardi G, Rossi F, Ricard-Blum S, Calzolai L.

Biointerphases. 2016 Dec 16;11(4):04B310.


Characterization of silver nanoparticles-alginate complexes by combined size separation and size measurement techniques.

António DC, Cascio C, Gilliland D, Nogueira AJ, Rossi F, Calzolai L.

Biointerphases. 2016 Dec 16;11(4):04B309.


Erratum to: Quantification of the cellular dose and characterization of nanoparticle transport during in vitro testing.

Rischitor G, Parracino M, La Spina R, Urbán P, Ojea-Jiménez I, Bellido E, Valsesia A, Gioria S, Capomaccio R, Kinsner-Ovaskainen A, Gilliland D, Rossi F, Colpo P.

Part Fibre Toxicol. 2016 Dec 9;13(1):66. No abstract available.


Quantification of the cellular dose and characterization of nanoparticle transport during in vitro testing.

Rischitor G, Parracino M, La Spina R, Urbán P, Ojea-Jiménez I, Bellido E, Valsesia A, Gioria S, Capomaccio R, Kinsner-Ovaskainen A, Gilliland D, Rossi F, Colpo P.

Part Fibre Toxicol. 2016 Aug 24;13(1):47. doi: 10.1186/s12989-016-0157-1. Erratum in: Part Fibre Toxicol. 2016 Dec 9;13(1):66. Urbán, Patrizia [corrected to Urbán, Patricia].


Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.

Severyn B, Nguyen T, Altman MD, Li L, Nagashima K, Naumov GN, Sathyanarayanan S, Cook E, Morris E, Ferrer M, Arthur B, Benita Y, Watters J, Loboda A, Hermes J, Gilliland DG, Cleary MA, Carroll PM, Strack P, Tudor M, Andersen JN.

J Biomol Screen. 2016 Oct;21(9):989-97. doi: 10.1177/1087057116658646. Epub 2016 Jul 26.


Effects of metal-bearing nanoparticles (Ag, Au, CdS, ZnO, SiO2) on developing zebrafish embryos.

Lacave JM, Retuerto A, Vicario-Parés U, Gilliland D, Oron M, Cajaraville MP, Orbea A.

Nanotechnology. 2016 Aug 12;27(32):325102. doi: 10.1088/0957-4484/27/32/325102. Epub 2016 Jul 1.


Inverse supercritical fluid extraction as a sample preparation method for the analysis of the nanoparticle content in sunscreen agents.

Müller D, Cattaneo S, Meier F, Welz R, de Vries T, Portugal-Cohen M, Antonio DC, Cascio C, Calzolai L, Gilliland D, de Mello A.

J Chromatogr A. 2016 Apr 1;1440:31-36. doi: 10.1016/j.chroma.2016.02.060. Epub 2016 Feb 26.


New Methods for the Analysis of Fat-Soluble Vitamins in Infant Formula and Adult Nutritionals.

Gilliland D.

J AOAC Int. 2016 Jan-Feb;99(1):15-8. doi: 10.5740/jaoacint.15-0250. Epub 2016 Jan 27. Review.


Multimethod approach for the detection and characterisation of food-grade synthetic amorphous silica nanoparticles.

Barahona F, Ojea-Jimenez I, Geiss O, Gilliland D, Barrero-Moreno J.

J Chromatogr A. 2016 Feb 5;1432:92-100. doi: 10.1016/j.chroma.2015.12.058. Epub 2015 Dec 23.


Highly Flexible Platform for Tuning Surface Properties of Silica Nanoparticles and Monitoring Their Biological Interaction.

Ojea-Jiménez I, Urbán P, Barahona F, Pedroni M, Capomaccio R, Ceccone G, Kinsner-Ovaskainen A, Rossi F, Gilliland D.

ACS Appl Mater Interfaces. 2016 Feb;8(7):4838-50. doi: 10.1021/acsami.5b11216. Epub 2016 Feb 10.


Role of the crystalline form of titanium dioxide nanoparticles: Rutile, and not anatase, induces toxic effects in Balb/3T3 mouse fibroblasts.

Uboldi C, Urbán P, Gilliland D, Bajak E, Valsami-Jones E, Ponti J, Rossi F.

Toxicol In Vitro. 2016 Mar;31:137-45. doi: 10.1016/j.tiv.2015.11.005. Epub 2015 Nov 10.


Dispersion Behaviour of Silica Nanoparticles in Biological Media and Its Influence on Cellular Uptake.

Halamoda-Kenzaoui B, Ceridono M, Colpo P, Valsesia A, Urbán P, Ojea-Jiménez I, Gioria S, Gilliland D, Rossi F, Kinsner-Ovaskainen A.

PLoS One. 2015 Oct 30;10(10):e0141593. doi: 10.1371/journal.pone.0141593. eCollection 2015.


Determination of the structure and morphology of gold nanoparticle-HSA protein complexes.

Capomaccio R, Jimenez IO, Colpo P, Gilliland D, Ceccone G, Rossi F, Calzolai L.

Nanoscale. 2015 Nov 14;7(42):17653-7. doi: 10.1039/c5nr05147a. Epub 2015 Oct 14.


Techniques and Protocols for Dispersing Nanoparticle Powders in Aqueous Media-Is there a Rationale for Harmonization?

Hartmann NB, Jensen KA, Baun A, Rasmussen K, Rauscher H, Tantra R, Cupi D, Gilliland D, Pianella F, Riego Sintes JM.

J Toxicol Environ Health B Crit Rev. 2015;18(6):299-326. doi: 10.1080/10937404.2015.1074969. Epub 2015 Sep 23. Review.


Accumulation and effects of sediment-associated silver nanoparticles to sediment-dwelling invertebrates.

Ramskov T, Forbes VE, Gilliland D, Selck H.

Aquat Toxicol. 2015 Sep;166:96-105. doi: 10.1016/j.aquatox.2015.07.002. Epub 2015 Jul 14.


Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells.

Cai X, Gao L, Teng L, Ge J, Oo ZM, Kumar AR, Gilliland DG, Mason PJ, Tan K, Speck NA.

Cell Stem Cell. 2015 Aug 6;17(2):165-77. doi: 10.1016/j.stem.2015.06.002. Epub 2015 Jul 9.


Mechanisms of Toxicity of Ag Nanoparticles in Comparison to Bulk and Ionic Ag on Mussel Hemocytes and Gill Cells.

Katsumiti A, Gilliland D, Arostegui I, Cajaraville MP.

PLoS One. 2015 Jun 10;10(6):e0129039. doi: 10.1371/journal.pone.0129039. eCollection 2015.


Cytotoxicity of Au, ZnO and SiO₂ NPs using in vitro assays with mussel hemocytes and gill cells: Relevance of size, shape and additives.

Katsumiti A, Arostegui I, Oron M, Gilliland D, Valsami-Jones E, Cajaraville MP.

Nanotoxicology. 2016;10(2):185-93. doi: 10.3109/17435390.2015.1039092. Epub 2015 May 12.


Cadmium sulfide quantum dots induce oxidative stress and behavioral impairments in the marine clam Scrobicularia plana.

Buffet PE, Zalouk-Vergnoux A, Poirier L, Lopes C, Risso-de-Faverney C, Guibbolini M, Gilliland D, Perrein-Ettajani H, Valsami-Jones E, Mouneyrac C.

Environ Toxicol Chem. 2015 Jul;34(7):1659-64. doi: 10.1002/etc.2967. Epub 2015 May 12.


Simultaneous determination of size and quantification of silica nanoparticles by asymmetric flow field-flow fractionation coupled to ICPMS using silica nanoparticles standards.

Barahona F, Geiss O, Urbán P, Ojea-Jimenez I, Gilliland D, Barrero-Moreno J.

Anal Chem. 2015 Mar 3;87(5):3039-47. doi: 10.1021/ac504698j. Epub 2015 Feb 17.


Loss of c-Cbl E3 ubiquitin ligase activity enhances the development of myeloid leukemia in FLT3-ITD mutant mice.

Taylor SJ, Thien CB, Dagger SA, Duyvestyn JM, Grove CS, Lee BH, Gilliland DG, Langdon WY.

Exp Hematol. 2015 Mar;43(3):191-206.e1. doi: 10.1016/j.exphem.2014.11.009. Epub 2014 Dec 19.


Changes in Caco-2 cells transcriptome profiles upon exposure to gold nanoparticles.

Bajak E, Fabbri M, Ponti J, Gioria S, Ojea-Jiménez I, Collotta A, Mariani V, Gilliland D, Rossi F, Gribaldo L.

Toxicol Lett. 2015 Mar 4;233(2):187-99. doi: 10.1016/j.toxlet.2014.12.008. Epub 2014 Dec 15.


Critical experimental evaluation of key methods to detect, size and quantify nanoparticulate silver.

Cascio C, Gilliland D, Rossi F, Calzolai L, Contado C.

Anal Chem. 2014 Dec 16;86(24):12143-51. doi: 10.1021/ac503307r. Epub 2014 Nov 25.


Solid-phase microextraction/gas chromatography-mass spectrometry method optimization for characterization of surface adsorption forces of nanoparticles.

Omanovic-Miklicanin E, Valzacchi S, Simoneau C, Gilliland D, Rossi F.

Anal Bioanal Chem. 2014 Oct;406(26):6629-36. doi: 10.1007/s00216-014-8078-z. Epub 2014 Aug 29.


Aneuploidogenic effects and DNA oxidation induced in vitro by differently sized gold nanoparticles.

Di Bucchianico S, Fabbrizi MR, Cirillo S, Uboldi C, Gilliland D, Valsami-Jones E, Migliore L.

Int J Nanomedicine. 2014 May 8;9:2191-204. doi: 10.2147/IJN.S58397. eCollection 2014.


Highly specific targeting of human leukocytes using gold nanoparticle-based biologically active conjugates.

Gibbs BF, Yasinska IM, Calzolai L, Gilliland D, Sumbayev VV.

J Biomed Nanotechnol. 2014 Jul;10(7):1259-66.


Detection of silver nanoparticles inside marine diatom Thalassiosira pseudonana by electron microscopy and focused ion beam.

García CP, Burchardt AD, Carvalho RN, Gilliland D, António DC, Rossi F, Lettieri T.

PLoS One. 2014 May 5;9(5):e96078. doi: 10.1371/journal.pone.0096078. eCollection 2014.


Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis.

Rampal R, Al-Shahrour F, Abdel-Wahab O, Patel JP, Brunel JP, Mermel CH, Bass AJ, Pretz J, Ahn J, Hricik T, Kilpivaara O, Wadleigh M, Busque L, Gilliland DG, Golub TR, Ebert BL, Levine RL.

Blood. 2014 May 29;123(22):e123-33. doi: 10.1182/blood-2014-02-554634. Epub 2014 Apr 16.


Fate and effects of metal-based nanoparticles in two marine invertebrates, the bivalve mollusc Scrobicularia plana and the annelid polychaete Hediste diversicolor.

Mouneyrac C, Buffet PE, Poirier L, Zalouk-Vergnoux A, Guibbolini M, Faverney CR, Gilliland D, Berhanu D, Dybowska A, Châtel A, Perrein-Ettajni H, Pan JF, Thomas-Guyon H, Reip P, Valsami-Jones E.

Environ Sci Pollut Res Int. 2014;21(13):7899-912. doi: 10.1007/s11356-014-2745-7. Epub 2014 Mar 21.


Simultaneous determination of vitamins D2 and D3 by electrospray ionization LC/MS/MS in infant formula and adult nutritionals: First Action 2012.11.

Gilliland DL, Black CK, Denison JE, Seipelt CT, Baugh S.

J AOAC Int. 2013 Nov-Dec;96(6):1387-95.


Cytotoxicity and cellular mechanisms involved in the toxicity of CdS quantum dots in hemocytes and gill cells of the mussel Mytilus galloprovincialis.

Katsumiti A, Gilliland D, Arostegui I, Cajaraville MP.

Aquat Toxicol. 2014 Aug;153:39-52. doi: 10.1016/j.aquatox.2014.02.003. Epub 2014 Feb 14.


Biochemical and behavioural responses of the marine polychaete Hediste diversicolor to cadmium sulfide quantum dots (CdS QDs): waterborne and dietary exposure.

Buffet PE, Poirier L, Zalouk-Vergnoux A, Lopes C, Amiard JC, Gaudin P, Risso-de Faverney C, Guibbolini M, Gilliland D, Perrein-Ettajani H, Valsami-Jones E, Mouneyrac C.

Chemosphere. 2014 Apr;100:63-70. doi: 10.1016/j.chemosphere.2013.12.069. Epub 2014 Jan 27.


A marine mesocosm study on the environmental fate of silver nanoparticles and toxicity effects on two endobenthic species: the ragworm Hediste diversicolor and the bivalve mollusc Scrobicularia plana.

Buffet PE, Zalouk-Vergnoux A, Châtel A, Berthet B, Métais I, Perrein-Ettajani H, Poirier L, Luna-Acosta A, Thomas-Guyon H, Risso-de Faverney C, Guibbolini M, Gilliland D, Valsami-Jones E, Mouneyrac C.

Sci Total Environ. 2014 Feb 1;470-471:1151-9. doi: 10.1016/j.scitotenv.2013.10.114. Epub 2013 Nov 16.


Size and mass determination of silver nanoparticles in an aqueous matrix using asymmetric flow field flow fractionation coupled to inductively coupled plasma mass spectrometer and ultraviolet-visible detectors.

Geiss O, Cascio C, Gilliland D, Franchini F, Barrero-Moreno J.

J Chromatogr A. 2013 Dec 20;1321:100-8. doi: 10.1016/j.chroma.2013.10.060. Epub 2013 Oct 27.


Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.

Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MAS, Scadden DT, Schreiber SL, Ebert BL, Golub TR.

Nat Chem Biol. 2013 Dec;9(12):840-848. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27.

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