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Items: 28


C-reactive protein during and after myocardial infarction in relation to cardiac injury and left ventricular function at follow-up.

Vanhaverbeke M, Veltman D, Pattyn N, De Crem N, Gillijns H, Cornelissen V, Janssens S, Sinnaeve PR.

Clin Cardiol. 2018 Sep;41(9):1201-1206. doi: 10.1002/clc.23017. Epub 2018 Sep 20.


Molecular signature of progenitor cells isolated from young and adult human hearts.

Walravens AS, Vanhaverbeke M, Ottaviani L, Gillijns H, Trenson S, Driessche NV, Luttun A, Meyns B, Herijgers P, Rega F, Heying R, Sampaolesi M, Janssens S.

Sci Rep. 2018 Jun 18;8(1):9266. doi: 10.1038/s41598-018-26969-2.


Sustained Placental Growth Factor-2 Treatment Does Not Aggravate Advanced Atherosclerosis in Ischemic Cardiomyopathy.

Wu M, Pokreisz P, Swinnen M, Caluwe E, Gillijns H, Vanden Driessche N, Casazza A, Verbeken E, Collen D, Janssens S.

J Cardiovasc Transl Res. 2017 Aug;10(4):348-358. doi: 10.1007/s12265-017-9742-4. Epub 2017 Apr 10.


Decreased Soluble Guanylate Cyclase Contributes to Cardiac Dysfunction Induced by Chronic Doxorubicin Treatment in Mice.

Vandenwijngaert S, Swinnen M, Walravens AS, Beerens M, Gillijns H, Caluwé E, Tainsh RE, Nathan DI, Allen K, Brouckaert P, Bartunek J, Scherrer-Crosbie M, Bloch KD, Bloch DB, Janssens SP, Buys ES.

Antioxid Redox Signal. 2017 Feb 1;26(4):153-164. doi: 10.1089/ars.2015.6542. Epub 2016 Sep 8.


Right ventricular and pulmonary vascular reserve in asymptomatic BMPR2 mutation carriers.

Claessen G, La Gerche A, Petit T, Gillijns H, Bogaert J, Claeys M, Dymarkowski S, Claus P, Delcroix M, Heidbuchel H.

J Heart Lung Transplant. 2017 Feb;36(2):148-156. doi: 10.1016/j.healun.2016.06.018. Epub 2016 Jun 24.


Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved.

Dauwe D, Pelacho B, Wibowo A, Walravens AS, Verdonck K, Gillijns H, Caluwe E, Pokreisz P, van Gastel N, Carmeliet G, Depypere M, Maes F, Vanden Driessche N, Droogne W, Van Cleemput J, Vanhaecke J, Prosper F, Verfaillie C, Luttun A, Janssens S.

J Am Heart Assoc. 2016 Apr 18;5(4):e002288. doi: 10.1161/JAHA.115.002288.


Concomitant Phosphodiesterase 5 Inhibition Enhances Myocardial Protection by Inhaled Nitric Oxide in Ischemia-Reperfusion Injury.

Lux A, Pokreisz P, Swinnen M, Caluwe E, Gillijns H, Szelid Z, Merkely B, Janssens SP.

J Pharmacol Exp Ther. 2016 Feb;356(2):284-92. doi: 10.1124/jpet.115.227850. Epub 2015 Nov 30.


Placental growth factor 2--A potential therapeutic strategy for chronic myocardial ischemia.

Wu M, Claus P, Vanden Driessche N, Reyns G, Pokreisz P, Gillijns H, Caluwe E, Bogaert J, Collen D, Janssens S.

Int J Cardiol. 2016 Jan 15;203:534-42. doi: 10.1016/j.ijcard.2015.10.177. Epub 2015 Oct 26.


Sildenafil improves exercise hemodynamics in Fontan patients.

Van De Bruaene A, La Gerche A, Claessen G, De Meester P, Devroe S, Gillijns H, Bogaert J, Claus P, Heidbuchel H, Gewillig M, Budts W.

Circ Cardiovasc Imaging. 2014 Mar;7(2):265-73. doi: 10.1161/CIRCIMAGING.113.001243. Epub 2014 Jan 29.


Increased cardiac myocyte PDE5 levels in human and murine pressure overload hypertrophy contribute to adverse LV remodeling.

Vandenwijngaert S, Pokreisz P, Hermans H, Gillijns H, Pellens M, Bax NA, Coppiello G, Oosterlinck W, Balogh A, Papp Z, Bouten CV, Bartunek J, D'hooge J, Luttun A, Verbeken E, Herregods MC, Herijgers P, Bloch KD, Janssens S.

PLoS One. 2013;8(3):e58841. doi: 10.1371/journal.pone.0058841. Epub 2013 Mar 18.


Differential effects of progenitor cell populations on left ventricular remodeling and myocardial neovascularization after myocardial infarction.

Dubois C, Liu X, Claus P, Marsboom G, Pokreisz P, Vandenwijngaert S, Dépelteau H, Streb W, Chaothawee L, Maes F, Gheysens O, Debyser Z, Gillijns H, Pellens M, Vandendriessche T, Chuah M, Collen D, Verbeken E, Belmans A, Van de Werf F, Bogaert J, Janssens S.

J Am Coll Cardiol. 2010 May 18;55(20):2232-43. doi: 10.1016/j.jacc.2009.10.081.


Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial reperfusion injury.

Szelid Z, Pokreisz P, Liu X, Vermeersch P, Marsboom G, Gillijns H, Pellens M, Verbeken E, Van de Werf F, Collen D, Janssens SP.

Basic Res Cardiol. 2010 Mar;105(2):169-79. doi: 10.1007/s00395-009-0077-4. Epub 2009 Dec 18.


Gender-specific modulation of the response to arterial injury by soluble guanylate cyclase α1.

Vermeersch P, Buys E, Sips P, Pokreisz P, Marsboom G, Gillijns H, Pellens M, Dewerchin M, Bloch KD, Brouckaert P, Janssens S.

Open Cardiovasc Med J. 2009 Aug 31;3:98-104. doi: 10.2174/1874192400903010098.


Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice.

Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, Marsboom G, Gheysens O, Vermeersch P, Biesmans L, Liu X, Gillijns H, Pellens M, Van Lommel A, Buys E, Schoonjans L, Vanhaecke J, Verbeken E, Sipido K, Herijgers P, Bloch KD, Janssens SP.

Circulation. 2009 Jan 27;119(3):408-16. doi: 10.1161/CIRCULATIONAHA.108.822072. Epub 2009 Jan 12.


Sustained endothelial progenitor cell dysfunction after chronic hypoxia-induced pulmonary hypertension.

Marsboom G, Pokreisz P, Gheysens O, Vermeersch P, Gillijns H, Pellens M, Liu X, Collen D, Janssens S.

Stem Cells. 2008 Apr;26(4):1017-26. doi: 10.1634/stemcells.2007-0562. Epub 2008 Feb 7.


Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion.

Liu X, Huang Y, Pokreisz P, Vermeersch P, Marsboom G, Swinnen M, Verbeken E, Santos J, Pellens M, Gillijns H, Van de Werf F, Bloch KD, Janssens S.

J Am Coll Cardiol. 2007 Aug 21;50(8):808-17. Epub 2007 Aug 6.


Soluble guanylate cyclase-alpha1 deficiency selectively inhibits the pulmonary vasodilator response to nitric oxide and increases the pulmonary vascular remodeling response to chronic hypoxia.

Vermeersch P, Buys E, Pokreisz P, Marsboom G, Ichinose F, Sips P, Pellens M, Gillijns H, Swinnen M, Graveline A, Collen D, Dewerchin M, Brouckaert P, Bloch KD, Janssens S.

Circulation. 2007 Aug 21;116(8):936-43. Epub 2007 Aug 6.


Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling.

Pokreisz P, Fleming I, Kiss L, Barbosa-Sicard E, Fisslthaler B, Falck JR, Hammock BD, Kim IH, Szelid Z, Vermeersch P, Gillijns H, Pellens M, Grimminger F, van Zonneveld AJ, Collen D, Busse R, Janssens S.

Hypertension. 2006 Apr;47(4):762-70. Epub 2006 Feb 27.


Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart.

Heymans S, Schroen B, Vermeersch P, Milting H, Gao F, Kassner A, Gillijns H, Herijgers P, Flameng W, Carmeliet P, Van de Werf F, Pinto YM, Janssens S.

Circulation. 2005 Aug 23;112(8):1136-44. Epub 2005 Aug 15.


Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.

Janssens S, Pokreisz P, Schoonjans L, Pellens M, Vermeersch P, Tjwa M, Jans P, Scherrer-Crosbie M, Picard MH, Szelid Z, Gillijns H, Van de Werf F, Collen D, Bloch KD.

Circ Res. 2004 May 14;94(9):1256-62. Epub 2004 Mar 25.


Preexisting antiadenoviral immunity and regional myocardial gene transfer: modulation by nitric oxide.

Szelid Z, Sinnaeve P, Vermeersch P, Gillijns H, Pellens M, Laurysens V, Van Pelt N, Flameng W, Sergeant P, Herijgers P, Pokreisz P, Van Zonneveld AJ, Verbeken E, Collen D, Janssens S.

Hum Gene Ther. 2002 Dec 10;13(18):2185-95.


Overexpression of a constitutively active protein kinase G mutant reduces neointima formation and in-stent restenosis.

Sinnaeve P, Chiche JD, Gillijns H, Van Pelt N, Wirthlin D, Van De Werf F, Collen D, Bloch KD, Janssens S.

Circulation. 2002 Jun 18;105(24):2911-6.


L-arginine administration reduces neointima formation after stent injury in rats by a nitric oxide-mediated mechanism.

Vermeersch P, Nong Z, Stabile E, Varenne O, Gillijns H, Pellens M, Van Pelt N, Hoylaerts M, De Scheerder I, Collen D, Janssens S.

Arterioscler Thromb Vasc Biol. 2001 Oct;21(10):1604-9.


Soluble guanylate cyclase alpha(1) and beta(1) gene transfer increases NO responsiveness and reduces neointima formation after balloon injury in rats via antiproliferative and antimigratory effects.

Sinnaeve P, Chiche JD, Nong Z, Varenne O, Van Pelt N, Gillijns H, Collen D, Bloch KD, Janssens S.

Circ Res. 2001 Jan 19;88(1):103-9.


Percutaneous gene therapy using recombinant adenoviruses encoding human herpes simplex virus thymidine kinase, human PAI-1, and human NOS3 in balloon-injured porcine coronary arteries.

Varenne O, Sinnaeve P, Gillijns H, Iung B, Laurysens V, Meurrens K, Bout B, Valerio D, Collen D, Janssens SP, Gerard RD.

Hum Gene Ther. 2000 Jun 10;11(9):1329-39.


Aerosol gene transfer with inducible nitric oxide synthase reduces hypoxic pulmonary hypertension and pulmonary vascular remodeling in rats.

Budts W, Pokreisz P, Nong Z, Van Pelt N, Gillijns H, Gerard R, Lyons R, Collen D, Bloch KD, Janssens S.

Circulation. 2000 Dec 5;102(23):2880-5.


Percutaneous adenoviral gene transfer into porcine coronary arteries: is catheter-based gene delivery adapted to coronary circulation?

Varenne O, Gerard RD, Sinnaeve P, Gillijns H, Collen D, Janssens S.

Hum Gene Ther. 1999 May 1;10(7):1105-15.


Local adenovirus-mediated transfer of human endothelial nitric oxide synthase reduces luminal narrowing after coronary angioplasty in pigs.

Varenne O, Pislaru S, Gillijns H, Van Pelt N, Gerard RD, Zoldhelyi P, Van de Werf F, Collen D, Janssens SP.

Circulation. 1998 Sep 1;98(9):919-26.


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