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Linkage between patients' characteristics and prescribed systemic treatments for Psoriasis: a semantic connectivity map analysis of the Swiss SDNTT registry.

Cazzaniga S, Anzengruber F, Augustin M, Boehncke WH, Borradori L, Conrad C, Cozzio A, Djamei V, French LE, Gilliet M, Häusermann P, Heidemeyer K, Itin P, Kolios AGA, Laffitte E, Maul JT, Mainetti C, Naldi L, Navarini AA, Rustenbach SJ, Simon D, Sorbe C, Streit M, Yawalkar N.

J Eur Acad Dermatol Venereol. 2019 Sep 28. doi: 10.1111/jdv.15983. [Epub ahead of print]


IL-1β Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells.

Weiss DI, Ma F, Merleev AA, Maverakis E, Gilliet M, Balin SJ, Bryson BD, Ochoa MT, Pellegrini M, Bloom BR, Modlin RL.

J Immunol. 2019 Aug 15;203(4):911-921. doi: 10.4049/jimmunol.1900318. Epub 2019 Jun 24.


Psoriasis Caught in the NET.

Di Domizio J, Gilliet M.

J Invest Dermatol. 2019 Jul;139(7):1426-1429. doi: 10.1016/j.jid.2019.04.020.


Autophagy links antimicrobial activity with antigen presentation in Langerhans cells.

Dang AT, Teles RM, Liu PT, Choi A, Legaspi A, Sarno EN, Ochoa MT, Parvatiyar K, Cheng G, Gilliet M, Bloom BR, Modlin RL.

JCI Insight. 2019 Apr 18;4(8). pii: 126955. doi: 10.1172/jci.insight.126955. eCollection 2019 Apr 18.


Targeted therapies and precision medicine for inflammatory skin diseases.

Gilliet M.

Eur J Dermatol. 2019 Apr 1;29(S1):19-24. doi: 10.1684/ejd.2019.3539.


IL-26 contributes to host defense against intracellular bacteria.

Dang AT, Teles RM, Weiss DI, Parvatiyar K, Sarno EN, Ochoa MT, Cheng G, Gilliet M, Bloom BR, Modlin RL.

J Clin Invest. 2019 Apr 2;129(5):1926-1939. doi: 10.1172/JCI99550. eCollection 2019 Apr 2.


Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9.

Lee EY, Zhang C, Di Domizio J, Jin F, Connell W, Hung M, Malkoff N, Veksler V, Gilliet M, Ren P, Wong GCL.

Nat Commun. 2019 Mar 4;10(1):1012. doi: 10.1038/s41467-019-08868-w.


Gender and age significantly determine patient needs and treatment goals in psoriasis - a lesson for practice.

Maul JT, Navarini AA, Sommer R, Anzengruber F, Sorbe C, Mrowietz U, Drach M, Blome C, Boehncke WH, Thaci D, Reich K, von Kiedrowski R, Körber A, Yawalkar N, Mainetti C, Laffitte E, Streit M, Rustenbach S, Conrad C, Borradori L, Gilliet M, Cozzio A, Itin P, Häusermann P, French LE, Radtke MA, Augustin M.

J Eur Acad Dermatol Venereol. 2019 Apr;33(4):700-708. doi: 10.1111/jdv.15324. Epub 2019 Jan 15.


Roger federer pourrait-il jouer en portant un large sombrero ?

Merat R, Gilliet M, Boehncke WH, Gaide O.

Rev Med Suisse. 2018 Aug 8;14(614):1422-1423. French. No abstract available.


TGFβ, Fibronectin and Integrin α5β1 Promote Invasion in Basal Cell Carcinoma.

Kuonen F, Surbeck I, Sarin KY, Dontenwill M, Rüegg C, Gilliet M, Oro AE, Gaide O.

J Invest Dermatol. 2018 Nov;138(11):2432-2442. doi: 10.1016/j.jid.2018.04.029. Epub 2018 Jul 14.


Netting Neutrophils Activate Autoreactive B Cells in Lupus.

Gestermann N, Di Domizio J, Lande R, Demaria O, Frasca L, Feldmeyer L, Di Lucca J, Gilliet M.

J Immunol. 2018 May 15;200(10):3364-3371. doi: 10.4049/jimmunol.1700778. Epub 2018 Apr 9.


[Emerging systemic treatments of atopic dermatitis].

Di Lucca-Chrisment J, Gilliet M.

Rev Med Suisse. 2018 Mar 28;14(600):685-689. French.


Innovation en dermatologie : il est temps de changer de mentalité !

Gilliet M, Boehncke WH.

Rev Med Suisse. 2018 Mar 28;14(600):659-660. French. No abstract available.


Psoriasis: from Pathogenesis to Targeted Therapies.

Conrad C, Gilliet M.

Clin Rev Allergy Immunol. 2018 Feb;54(1):102-113. doi: 10.1007/s12016-018-8668-1. Review.


TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis.

Conrad C, Di Domizio J, Mylonas A, Belkhodja C, Demaria O, Navarini AA, Lapointe AK, French LE, Vernez M, Gilliet M.

Nat Commun. 2018 Jan 2;9(1):25. doi: 10.1038/s41467-017-02466-4.


Diversification of human plasmacytoid predendritic cells in response to a single stimulus.

Alculumbre SG, Saint-André V, Di Domizio J, Vargas P, Sirven P, Bost P, Maurin M, Maiuri P, Wery M, Roman MS, Savey L, Touzot M, Terrier B, Saadoun D, Conrad C, Gilliet M, Morillon A, Soumelis V.

Nat Immunol. 2018 Jan;19(1):63-75. doi: 10.1038/s41590-017-0012-z. Epub 2017 Dec 4.


Drug Repurposing Approach Identifies a Synergistic Drug Combination of an Antifungal Agent and an Experimental Organometallic Drug for Melanoma Treatment.

Riedel T, Demaria O, Zava O, Joncic A, Gilliet M, Dyson PJ.

Mol Pharm. 2018 Jan 2;15(1):116-126. doi: 10.1021/acs.molpharmaceut.7b00764. Epub 2017 Dec 13.


Use of Dipeptidyl-Peptidase IV Inhibitors and Bullous Pemphigoid.

Schaffer C, Buclin T, Jornayvaz FR, Cazzaniga S, Borradori L, Gilliet M, Feldmeyer L.

Dermatology. 2017;233(5):401-403. doi: 10.1159/000480498. Epub 2017 Oct 18. No abstract available.


European Society for Dermatological Research (ESDR): Shifting Scope and Expanding Boundaries, Promoting Cutaneous Biology Research across Europe and beyond.

Schmuth M, Gilliet M, Griffiths CEM, Barker JN.

J Invest Dermatol. 2017 Sep;137(9):1817-1819. doi: 10.1016/j.jid.2017.07.821. No abstract available.


Choisir le bon médicament pour votre patient : evidence vs eminence-based medicine.

Boehncke WH, Gilliet M.

Rev Med Suisse. 2017 Mar 29;13(556):675-676. French. No abstract available.


Non-Melanoma Skin Cancers of the Fronto-Temporal Area Preferentially Localize in the Proximity of Arterial Blood Vessels.

Kuonen F, Gilliet M, Perrier P.

Dermatology. 2017;233(2-3):199-204. doi: 10.1159/000468537. Epub 2017 May 9.


Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation.

Zwicker S, Hattinger E, Bureik D, Batycka-Baran A, Schmidt A, Gerber PA, Rothenfusser S, Gilliet M, Ruzicka T, Wolf R.

PLoS One. 2017 Apr 19;12(4):e0175153. doi: 10.1371/journal.pone.0175153. eCollection 2017.


Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growth.

Bujisic B, De Gassart A, Tallant R, Demaria O, Zaffalon L, Chelbi S, Gilliet M, Bertoni F, Martinon F.

Blood. 2017 Apr 27;129(17):2420-2428. doi: 10.1182/blood-2016-09-741348. Epub 2017 Feb 6.


Interleukin 23-Helper T Cell 17 Axis as a Treatment Target for Pityriasis Rubra Pilaris.

Feldmeyer L, Mylonas A, Demaria O, Mennella A, Yawalkar N, Laffitte E, Hohl D, Gilliet M, Conrad C.

JAMA Dermatol. 2017 Apr 1;153(4):304-308. doi: 10.1001/jamadermatol.2016.5384.


Superiority in Quality of Life Improvement of Biologics over Conventional Systemic Drugs in a Swiss Real-Life Psoriasis Registry.

Jungo P, Maul JT, Djamei V, von Felten S, Kolios AGA, Czernielewsk J, Yawalkar N, Odermatt O, Laffitte E, Anliker M, Streit M, Augustin M, Conrad C, Hafner J, Boehncke WH, Gilliet M, Itin P, French LE, Navarini AA, Häusermann P.

Dermatology. 2016;232(6):655-663. doi: 10.1159/000455042. Epub 2017 Jan 20.


Efficacy and Survival of Systemic Psoriasis Treatments: An Analysis of the Swiss Registry SDNTT.

Maul JT, Djamei V, Kolios AGA, Meier B, Czernielewski J, Jungo P, Yawalkar N, Mainetti C, Laffitte E, Spehr C, Anliker M, Streit M, Augustin M, Rustenbach S, Conrad C, Hafner J, Boehncke WH, Borradori L, Gilliet M, Itin P, French LE, Häusermann P, Navarini AA.

Dermatology. 2016;232(6):640-647. doi: 10.1159/000452740. Epub 2017 Jan 12.


Xenotransplantation Model of Psoriasis.

Di Domizio J, Conrad C, Gilliet M.

Methods Mol Biol. 2017;1559:83-90. doi: 10.1007/978-1-4939-6786-5_7.


Colonisation of basal cell carcinoma by lentigo maligna: a case report, review of the literature, and series follow-up.

Kuonen F, Aschwanden J, Dimaio DJ, Elston DM, Gilliet M, Hohl D, Gaide O.

Eur J Dermatol. 2016 Oct 1;26(5):465-469. Review.


Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

De Gassart A, Demaria O, Panes R, Zaffalon L, Ryazanov AG, Gilliet M, Martinon F.

EMBO Rep. 2016 Oct;17(10):1471-1484. Epub 2016 Aug 29.


Swiss S1 Guidelines on the Systemic Treatment of Psoriasis Vulgaris.

Kolios AG, Yawalkar N, Anliker M, Boehncke WH, Borradori L, Conrad C, Gilliet M, Häusermann P, Itin P, Laffitte E, Mainetti C, French LE, Navarini AA.

Dermatology. 2016;232(4):385-406. doi: 10.1159/000445681. Epub 2016 Jun 21.


[The skin microbiota: a colossus steps into the spotlight].

Di Domizio J, Pagnoni A, Huber M, Hohl D, Gilliet M.

Rev Med Suisse. 2016 Mar 30;12(512):660-4. Review. French.


Dermatologie: en route vers la médecine de precision.

Gilliet M, Wolf-Henning B.

Rev Med Suisse. 2016 Mar 30;12(512):627-8. French. No abstract available.


A review of immune amplification via ligand clustering by self-assembled liquid-crystalline DNA complexes.

Lee EY, Lee CK, Schmidt NW, Jin F, Lande R, Curk T, Frenkel D, Dobnikar J, Gilliet M, Wong GCL.

Adv Colloid Interface Sci. 2016 Jun;232:17-24. doi: 10.1016/j.cis.2016.02.003. Epub 2016 Feb 19. Review.


PASS Syndrome: An IL-1-Driven Autoinflammatory Disease.

Leuenberger M, Berner J, Di Lucca J, Fischer L, Kaparos N, Conrad C, Hohl D, So A, Gilliet M.

Dermatology. 2016;232(2):254-8. doi: 10.1159/000443648. Epub 2016 Feb 27.


CD28 Deficiency Enhances Type I IFN Production by Murine Plasmacytoid Dendritic Cells.

Macal M, Tam MA, Hesser C, Di Domizio J, Leger P, Gilliet M, Zuniga EI.

J Immunol. 2016 Feb 15;196(4):1900-9. doi: 10.4049/jimmunol.1501658. Epub 2016 Jan 15.


SYNTHETIC BIOLOGY. Designer cells finely tuned for therapy.

Di Domizio J, Gilliet M.

Science. 2015 Dec 18;350(6267):1478-9. doi: 10.1126/science.aad9464. No abstract available.


IL-17 receptor A and adenosine deaminase 2 deficiency in siblings with recurrent infections and chronic inflammation.

Fellmann F, Angelini F, Wassenberg J, Perreau M, Arenas Ramirez N, Simon G, Boyman O, Demaria O, Christen-Zaech S, Hohl D, Belfiore M, von Scheven-Gete A, Gilliet M, Bochud PY, Perrin Y, Beck Popovic M, Bart PA, Beckmann JS, Martinet D, Hofer M.

J Allergy Clin Immunol. 2016 Apr;137(4):1189-1196.e2. doi: 10.1016/j.jaci.2015.07.053. Epub 2015 Nov 20.


STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.

Demaria O, De Gassart A, Coso S, Gestermann N, Di Domizio J, Flatz L, Gaide O, Michielin O, Hwu P, Petrova TV, Martinon F, Modlin RL, Speiser DE, Gilliet M.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15408-13. doi: 10.1073/pnas.1512832112. Epub 2015 Nov 25.


T(H)17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26.

Meller S, Di Domizio J, Voo KS, Friedrich HC, Chamilos G, Ganguly D, Conrad C, Gregorio J, Le Roy D, Roger T, Ladbury JE, Homey B, Watowich S, Modlin RL, Kontoyiannis DP, Liu YJ, Arold ST, Gilliet M.

Nat Immunol. 2015 Sep;16(9):970-9. doi: 10.1038/ni.3211. Epub 2015 Jul 13.


Liquid-crystalline ordering of antimicrobial peptide-DNA complexes controls TLR9 activation.

Schmidt NW, Jin F, Lande R, Curk T, Xian W, Lee C, Frasca L, Frenkel D, Dobnikar J, Gilliet M, Wong GC.

Nat Mater. 2015 Jul;14(7):696-700. doi: 10.1038/nmat4298. Epub 2015 Jun 8.


[Psoriasis: advances and challenges in 2015].

Conrad C, Triboulet C, Gilliet M.

Rev Med Suisse. 2015 Apr 1;11(468):754, 756-8. French.


[Warning shot of the WHO].

Boehncke WH, Gilliet M.

Rev Med Suisse. 2015 Apr 1;11(468):751-2. French. No abstract available.


Corrigendum: the antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis.

Lande R, Botti E, Jandus C, Dojcinovic D, Fanelli G, Conrad C, Chamilos G, Feldmeyer L, Marinari B, Chon S, Vence L, Riccieri V, Guillaume P, Navarini AA, Romero P, Costanzo A, Piccolella E, Gilliet M, Frasca L.

Nat Commun. 2015 Mar 11;6:6595. doi: 10.1038/ncomms7595. No abstract available.


The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis.

Lande R, Botti E, Jandus C, Dojcinovic D, Fanelli G, Conrad C, Chamilos G, Feldmeyer L, Marinari B, Chon S, Vence L, Riccieri V, Guillaume P, Navarini AA, Romero P, Costanzo A, Piccolella E, Gilliet M, Frasca L.

Nat Commun. 2014 Dec 3;5:5621. doi: 10.1038/ncomms6621. Erratum in: Nat Commun. 2015;6:6595.


Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation.

Roychoudhuri R, Lefebvre F, Honda M, Pan L, Ji Y, Klebanoff CA, Nichols CN, Fourati S, Hegazy AN, Goulet JP, Gattinoni L, Nabel GJ, Gilliet M, Cameron M, Restifo NP, Sékaly RP, Flatz L.

Vaccine. 2015 Feb 11;33(7):914-23. doi: 10.1016/j.vaccine.2014.10.007. Epub 2014 Nov 1.


Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self-DNA.

Lande R, Chamilos G, Ganguly D, Demaria O, Frasca L, Durr S, Conrad C, Schröder J, Gilliet M.

Eur J Immunol. 2015 Jan;45(1):203-13. doi: 10.1002/eji.201344277. Epub 2014 Nov 13.


Immune sensing of nucleic acids in inflammatory skin diseases.

Demaria O, Di Domizio J, Gilliet M.

Semin Immunopathol. 2014 Sep;36(5):519-29. doi: 10.1007/s00281-014-0445-5. Epub 2014 Sep 16. Review.


Comparison of molecular signatures from multiple skin diseases identifies mechanisms of immunopathogenesis.

Inkeles MS, Scumpia PO, Swindell WR, Lopez D, Teles RMB, Graeber TG, Meller S, Homey B, Elder JT, Gilliet M, Modlin RL, Pellegrini M.

J Invest Dermatol. 2015 Jan;135(1):151-159. doi: 10.1038/jid.2014.352. Epub 2014 Aug 11.


Plasmacytoid dendritic cells in melanoma: can we revert bad into good?

Di Domizio J, Demaria O, Gilliet M.

J Invest Dermatol. 2014 Jul;134(7):1797-1800. doi: 10.1038/jid.2014.155.


Prurigo nodularis: retrospective study of 13 cases managed with methotrexate.

Spring P, Gschwind I, Gilliet M.

Clin Exp Dermatol. 2014 Jun;39(4):468-73. doi: 10.1111/ced.12365.


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