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Items: 1 to 50 of 68

1.

MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance.

Sale MJ, Balmanno K, Saxena J, Ozono E, Wojdyla K, McIntyre RE, Gilley R, Woroniuk A, Howarth KD, Hughes G, Dry JR, Arends MJ, Caro P, Oxley D, Ashton S, Adams DJ, Saez-Rodriguez J, Smith PD, Cook SJ.

Nat Commun. 2019 May 2;10(1):2030. doi: 10.1038/s41467-019-09438-w.

2.

House dust mite exposure attenuates influenza A infection in a mouse model of pulmonary allergic inflammation.

Hu Q, Gilley RP, Dube PH.

Microb Pathog. 2019 Apr;129:242-249. doi: 10.1016/j.micpath.2019.02.019. Epub 2019 Feb 15.

PMID:
30776411
3.

Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1.

Guo H, Gilley RP, Fisher A, Lane R, Landsteiner VJ, Ragan KB, Dovey CM, Carette JE, Upton JW, Mocarski ES, Kaiser WJ.

Cell Death Dis. 2018 Jul 26;9(8):816. doi: 10.1038/s41419-018-0868-3.

4.

Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing.

Shenoy AT, Brissac T, Gilley RP, Kumar N, Wang Y, Gonzalez-Juarbe N, Hinkle WS, Daugherty SC, Shetty AC, Ott S, Tallon LJ, Deshane J, Tettelin H, Orihuela CJ.

PLoS Pathog. 2017 Aug 25;13(8):e1006582. doi: 10.1371/journal.ppat.1006582. eCollection 2017 Aug.

5.

Murine cytomegalovirus IE3-dependent transcription is required for DAI/ZBP1-mediated necroptosis.

Sridharan H, Ragan KB, Guo H, Gilley RP, Landsteiner VJ, Kaiser WJ, Upton JW.

EMBO Rep. 2017 Aug;18(8):1429-1441. doi: 10.15252/embr.201743947. Epub 2017 Jun 12.

6.

Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling.

Cook SJ, Stuart K, Gilley R, Sale MJ.

FEBS J. 2017 Dec;284(24):4177-4195. doi: 10.1111/febs.14122. Epub 2017 Jun 18. Review.

7.

Visualization of Endogenous ERK1/2 in Cells with a Bioorthogonal Covalent Probe.

Sipthorp J, Lebraud H, Gilley R, Kidger AM, Okkenhaug H, Saba-El-Leil M, Meloche S, Caunt CJ, Cook SJ, Heightman TD.

Bioconjug Chem. 2017 Jun 21;28(6):1677-1683. doi: 10.1021/acs.bioconjchem.7b00152. Epub 2017 May 12.

PMID:
28449575
8.

Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties.

Lizcano A, Akula Suresh Babu R, Shenoy AT, Saville AM, Kumar N, D'Mello A, Hinojosa CA, Gilley RP, Segovia J, Mitchell TJ, Tettelin H, Orihuela CJ.

Microbes Infect. 2017 Jun;19(6):323-333. doi: 10.1016/j.micinf.2017.04.001. Epub 2017 Apr 10.

9.

A RIPtide Protects Neurons from Infection.

Gilley RP, Kaiser WJ.

Cell Host Microbe. 2017 Apr 12;21(4):415-416. doi: 10.1016/j.chom.2017.03.014.

10.

Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia.

González-Juarbe N, Bradley KM, Shenoy AT, Gilley RP, Reyes LF, Hinojosa CA, Restrepo MI, Dube PH, Bergman MA, Orihuela CJ.

Cell Death Differ. 2017 May;24(5):917-928. doi: 10.1038/cdd.2017.49. Epub 2017 Apr 7.

11.

Long-term Formation of Aggressive Bony Lesions in Dogs with Mid-Diaphyseal Fractures Stabilized with Metallic Plates: Incidence in a Tertiary Referral Hospital Population.

Gilley RS, Hiebert E, Clapp K, Bartl-Wilson L, Nappier M, Werre S, Barnes K.

Front Vet Sci. 2017 Jan 31;4:3. doi: 10.3389/fvets.2017.00003. eCollection 2017.

12.

A Non-Human Primate Model of Severe Pneumococcal Pneumonia.

Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Shenoy AT, Gilley RP, Gonzalez-Juarbe N, Noda JR, Winter VT, de la Garza MA, Shade RE, Coalson JJ, Giavedoni LD, Anzueto A, Orihuela CJ.

PLoS One. 2016 Nov 17;11(11):e0166092. doi: 10.1371/journal.pone.0166092. eCollection 2016.

13.

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis.

Amalakuhan B, Habib SA, Mangat M, Reyes LF, Rodriguez AH, Hinojosa CA, Soni NJ, Gilley RP, Bustamante CA, Anzueto A, Levine SM, Peters JI, Aliberti S, Sibila O, Chalmers JD, Torres A, Waterer GW, Martin-Loeches I, Bordon J, Blanquer J, Sanz F, Marcos PJ, Rello J, Ramirez J, Solé-Violán J, Luna CM, Feldman C, Witzenrath M, Wunderink RG, Stolz D, Wiemken TL, Shindo Y, Dela Cruz CS, Orihuela CJ, Restrepo MI.

Cytokine. 2016 Dec;88:267-273. doi: 10.1016/j.cyto.2016.08.028. Epub 2016 Oct 1.

14.

Neuraminidase A-Exposed Galactose Promotes Streptococcus pneumoniae Biofilm Formation during Colonization.

Blanchette KA, Shenoy AT, Milner J 2nd, Gilley RP, McClure E, Hinojosa CA, Kumar N, Daugherty SC, Tallon LJ, Ott S, King SJ, Ferreira DM, Gordon SB, Tettelin H, Orihuela CJ.

Infect Immun. 2016 Sep 19;84(10):2922-32. doi: 10.1128/IAI.00277-16. Print 2016 Oct.

15.

Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.

Lochhead PA, Clark J, Wang LZ, Gilmour L, Squires M, Gilley R, Foxton C, Newell DR, Wedge SR, Cook SJ.

Cell Cycle. 2016;15(4):506-18. doi: 10.1080/15384101.2015.1120915.

16.

Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion.

Gilley RP, González-Juarbe N, Shenoy AT, Reyes LF, Dube PH, Restrepo MI, Orihuela CJ.

Infect Immun. 2016 Apr 22;84(5):1457-69. doi: 10.1128/IAI.00007-16. Print 2016 May.

17.

Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia.

González-Juarbe N, Gilley RP, Hinojosa CA, Bradley KM, Kamei A, Gao G, Dube PH, Bergman MA, Orihuela CJ.

PLoS Pathog. 2015 Dec 11;11(12):e1005337. doi: 10.1371/journal.ppat.1005337. eCollection 2015 Dec.

18.

Comparison of autogenous cancellous bone grafting and extracorporeal shock wave therapy on osteotomy healing in the tibial tuberosity advancement procedure in dogs. Radiographic densitometric evaluation.

Barnes K, Lanz O, Werre S, Clapp K, Gilley R.

Vet Comp Orthop Traumatol. 2015;28(3):207-14. doi: 10.3415/VCOT-14-10-0156. Epub 2015 Apr 22.

PMID:
25899991
19.

Pneumococci in biofilms are non-invasive: implications on nasopharyngeal colonization.

Gilley RP, Orihuela CJ.

Front Cell Infect Microbiol. 2014 Nov 6;4:163. doi: 10.3389/fcimb.2014.00163. eCollection 2014. Review.

20.

Lipidation of the FPI protein IglE contributes to Francisella tularensis ssp. novicida intramacrophage replication and virulence.

Nguyen JQ, Gilley RP, Zogaj X, Rodriguez SA, Klose KE.

Pathog Dis. 2014 Oct;72(1):10-8. doi: 10.1111/2049-632X.12167. Epub 2014 May 8.

21.

Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation.

Cope CL, Gilley R, Balmanno K, Sale MJ, Howarth KD, Hampson M, Smith PD, Guichard SM, Cook SJ.

J Cell Sci. 2014 Feb 15;127(Pt 4):788-800. doi: 10.1242/jcs.137588. Epub 2013 Dec 20.

22.

Adaptation to chronic mTOR inhibition in cancer and in aging.

Gilley R, Balmanno K, Cope CL, Cook SJ.

Biochem Soc Trans. 2013 Aug;41(4):956-61. doi: 10.1042/BST20130080. Review.

PMID:
23863163
23.

Estrogen prevents cardiac and vascular failure in the 'listless' zebrafish (Danio rerio) developmental model.

Allgood OE Jr, Hamad A, Fox J, Defrank A, Gilley R, Dawson F, Sykes B, Underwood TJ, Naylor RC, Briggs AA, Lassiter CS, Bell WE, Turner JE.

Gen Comp Endocrinol. 2013 Aug 1;189:33-42. doi: 10.1016/j.ygcen.2013.04.016. Epub 2013 Apr 28.

PMID:
23631900
24.

ERK5 and its role in tumour development.

Lochhead PA, Gilley R, Cook SJ.

Biochem Soc Trans. 2012 Feb;40(1):251-6. doi: 10.1042/BST20110663. Review.

PMID:
22260700
25.

CDK1, not ERK1/2 or ERK5, is required for mitotic phosphorylation of BIMEL.

Gilley R, Lochhead PA, Balmanno K, Oxley D, Clark J, Cook SJ.

Cell Signal. 2012 Jan;24(1):170-80. doi: 10.1016/j.cellsig.2011.08.018. Epub 2011 Sep 8.

PMID:
21924351
26.

Structural and functional effects of acoustic exposure in goldfish: evidence for tonotopy in the teleost saccule.

Smith ME, Schuck JB, Gilley RR, Rogers BD.

BMC Neurosci. 2011 Feb 15;12:19. doi: 10.1186/1471-2202-12-19.

27.

Meniscal injury in dogs with cranial cruciate ligament rupture.

Franklin SP, Gilley RS, Palmer RH.

Compend Contin Educ Vet. 2010 Oct;32(10):E1-10; quiz E11. Review.

PMID:
21308661
28.

Surgical stabilization of an occipitoatlantoaxial malformation in an adult dog.

Galban EM, Gilley RS, Long SN.

Vet Surg. 2010 Dec;39(8):1001-4. doi: 10.1111/j.1532-950X.2010.00734.x. Epub 2010 Sep 29.

PMID:
20880141
29.

Incidence of and risk factors for postoperative pneumonia in dogs anesthetized for diagnosis or treatment of intervertebral disk disease.

Java MA, Drobatz KJ, Gilley RS, Long SN, Kushner LI, King LG.

J Am Vet Med Assoc. 2009 Aug 1;235(3):281-7. doi: 10.2460/javma.235.3.281.

PMID:
19650699
30.

External fixator clamp reuse degrades clamp mechanical performance.

Gilley RS, Beason DP, Snyder DM, Boston RC, Radin A, Kapatkin AS, Smith GK, Soslowsky LJ.

Vet Surg. 2009 Jun;38(4):530-6. doi: 10.1111/j.1532-950X.2009.00521.x.

PMID:
19538676
31.

OP-1 augments glucocorticoid-inhibited fracture healing in a rat fracture model.

Gilley RS, Wallace LJ, Bourgeault CA, Kidder LS, Bechtold JE.

Clin Orthop Relat Res. 2009 Dec;467(12):3104-12. doi: 10.1007/s11999-009-0782-1. Epub 2009 Mar 20.

32.

ERK1/2, but not ERK5, is necessary and sufficient for phosphorylation and activation of c-Fos.

Gilley R, March HN, Cook SJ.

Cell Signal. 2009 Jun;21(6):969-77. doi: 10.1016/j.cellsig.2009.02.006. Epub 2009 Feb 25.

PMID:
19249353
33.

Mandibular reconstruction after gunshot trauma in a dog by use of recombinant human bone morphogenetic protein-2.

Lewis JR, Boudrieau RJ, Reiter AM, Seeherman HJ, Gilley RS.

J Am Vet Med Assoc. 2008 Nov 15;233(10):1598-604. doi: 10.2460/javma.233.10.1598.

PMID:
19014295
34.

Kinetic gait analysis of healthy dogs on two different surfaces.

Kapatkin AS, Arbittier G, Kass PH, Gilley RS, Smith GK.

Vet Surg. 2007 Aug;36(6):605-8.

PMID:
17686136
35.

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL.

Ewings KE, Hadfield-Moorhouse K, Wiggins CM, Wickenden JA, Balmanno K, Gilley R, Degenhardt K, White E, Cook SJ.

EMBO J. 2007 Jun 20;26(12):2856-67. Epub 2007 May 24.

36.

The duration of ERK1/2 activity determines the activation of c-Fos and Fra-1 and the composition and quantitative transcriptional output of AP-1.

Chalmers CJ, Gilley R, March HN, Balmanno K, Cook SJ.

Cell Signal. 2007 Apr;19(4):695-704. Epub 2006 Sep 15.

PMID:
17052890
37.

Complications and radiographic findings following cemented total hip replacement: a retrospective evaluation of 97 dogs.

Bergh MS, Gilley RS, Shofer FS, Kapatkin AS.

Vet Comp Orthop Traumatol. 2006;19(3):172-9.

PMID:
16972000
38.

Absolute and relative cell counts for synovial fluid from clinically normal shoulder and stifle joints in cats.

Pacchiana PD, Gilley RS, Wallace LJ, Hayden DW, Feeney DA, Jessen CR, Aird B.

J Am Vet Med Assoc. 2004 Dec 15;225(12):1866-70.

PMID:
15643835
39.

Treatment with a combined cystopexy-colopexy for dysuria and rectal prolapse after bilateral perineal herniorrhaphy in a dog.

Gilley RS, Caywood DD, Lulich JP, Bowersox TS.

J Am Vet Med Assoc. 2003 Jun 15;222(12):1717-21, 1706.

PMID:
12830864
40.

Clinical and pathologic analyses of bicipital tenosynovitis in dogs.

Gilley RS, Wallace LJ, Hayden DW.

Am J Vet Res. 2002 Mar;63(3):402-7.

PMID:
11911575
41.

A comparative mechanical study of 3 external fixator clamps.

Gilley RS, Bourgeault CA, Wallace LJ, Bechtold JE.

Vet Surg. 2001 Jul-Aug;30(4):341-50.

PMID:
11443595
42.

Induction of mucosal and systemic antibody specific for SeMF3 of Streptococcus equi by intranasal vaccination using a sucrose acetate isobutyrate based delivery system.

Nally JE, Artiushin S, Sheoran AS, Burns PJ, Simon B, Gilley RM, Gibson J, Sullivan S, Timoney JF.

Vaccine. 2000 Oct 15;19(4-5):492-7.

PMID:
11027813
43.

Combined systemic and mucosal immunization with microsphere-encapsulated inactivated simian immunodeficiency virus elicits serum, vaginal, and tracheal antibody responses in female rhesus macaques.

Israel ZR, Gettie A, Ishizaka ST, Mishkin EM, Staas J, Gilley R, Montefiori D, Marx PA, Eldridge JH.

AIDS Res Hum Retroviruses. 1999 Aug 10;15(12):1121-36.

PMID:
10461832
44.

Induction of mucosal antibody responses by microsphere-encapsulated formalin-inactivated simian immunodeficiency virus in a male urethral challenge model.

Ishizaka ST, Israel ZR, Gettie A, Mishkin EM, Staas JK, Gilley RM, Dailey PJ, Montefiori DC, Marx PA, Eldridge JH.

Vaccine. 1999 Jul 16;17(22):2817-25.

PMID:
10438051
45.
46.

Induction of protective immune responses against Venezuelan equine encephalitis (VEE) virus aerosol challenge with microencapsulated VEE virus vaccine.

Greenway TE, Eldridge JH, Ludwig G, Staas JK, Smith JF, Gilley RM, Michalek SM.

Vaccine. 1998 Aug;16(13):1314-23.

PMID:
9682396
47.
48.
49.

Enhancement of protective immune responses to Venezuelan equine encephalitis (VEE) virus with microencapsulated vaccine.

Greenway TE, Eldridge JH, Ludwig G, Staas JK, Smith JF, Gilley RM, Michalek SM.

Vaccine. 1995;13(15):1411-20.

PMID:
8578818
50.

Oral vaccine models: multiple delivery systems employing tetanus toxoid.

Jackson RJ, Staats HF, Xu-Amano J, Takahashi I, Kiyono H, Hudson ME, Gilley RM, Chatfield SN, McGhee JR.

Ann N Y Acad Sci. 1994 Aug 15;730:217-34.

PMID:
8080173

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