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Items: 1 to 50 of 96

1.

DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses.

Wu Y, Pons V, Noël R, Kali S, Shtanko O, Davey RA, Popoff MR, Tordo N, Gillet D, Cintrat JC, Barbier J.

ACS Med Chem Lett. 2019 Jul 2;10(8):1140-1147. doi: 10.1021/acsmedchemlett.9b00155. eCollection 2019 Aug 8.

PMID:
31413797
2.

Antiviral Effect of Retro-2.1 against Herpes Simplex Virus Type 2 In Vitro.

Dai W, Wu Y, Bi J, Wang J, Wang S, Kong W, Barbier J, Cintrat JC, Gao F, Jiang Z, Gillet D, Su W, Jiang C.

J Microbiol Biotechnol. 2018 Jun 28;28(6):849-859. doi: 10.4014/jmb.1712.12052.

3.

Ribosome Inactivating Proteins: From Plant Defense to Treatments against Human Misuse or Diseases.

Barbier J, Gillet D.

Toxins (Basel). 2018 Apr 18;10(4). pii: E160. doi: 10.3390/toxins10040160.

4.

Efficacy and safety of a T-type calcium channel blocker in patients with neuropathic pain: A proof-of-concept, randomized, double-blind and controlled trial.

Kerckhove N, Pereira B, Soriot-Thomas S, Alchaar H, Deleens R, Hieng VS, Serra E, Lanteri-Minet M, Arcagni P, Picard P, Lefebvre-Kuntz D, Maindet C, Mick G, Balp L, Lucas C, Creach C, Letellier M, Martinez V, Navez M, Delbrouck D, Kuhn E, Piquet E, Bozzolo E, Brosse C, Lietar B, Marcaillou F, Hamdani A, Leroux-Bromberg N, Perier Y, Vergne-Salle P, Gov C, Delage N, Gillet D, Romettino S, Richard D, Mallet C, Bernard L, Lambert C, Dubray C, Duale C, Eschalier A.

Eur J Pain. 2018 Aug;22(7):1321-1330. doi: 10.1002/ejp.1221. Epub 2018 Apr 18.

PMID:
29577519
5.

Antiviral Effects of ABMA against Herpes Simplex Virus Type 2 In Vitro and In Vivo.

Dai W, Wu Y, Bi J, Wang S, Li F, Kong W, Barbier J, Cintrat JC, Gao F, Gillet D, Su W, Jiang C.

Viruses. 2018 Mar 9;10(3). pii: E119. doi: 10.3390/v10030119.

6.

Screening of a Drug Library Identifies Inhibitors of Cell Intoxication by CNF1.

Mahtal N, Brewee C, Pichard S, Visvikis O, Cintrat JC, Barbier J, Lemichez E, Gillet D.

ChemMedChem. 2018 Apr 6;13(7):754-761. doi: 10.1002/cmdc.201700631. Epub 2018 Feb 27.

PMID:
29359495
7.

Retro-2 and its dihydroquinazolinone derivatives inhibit filovirus infection.

Shtanko O, Sakurai Y, Reyes AN, Noël R, Cintrat JC, Gillet D, Barbier J, Davey RA.

Antiviral Res. 2018 Jan;149:154-163. doi: 10.1016/j.antiviral.2017.11.016. Epub 2017 Nov 22.

8.

ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.

Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg JA, Kali S, Davey RA, Laporte J, Bouclier C, Yousfi R, Aubenque C, Merer G, Gobbo E, Lopez R, Gillet C, Cojean S, Popoff MR, Clayette P, Le Grand R, Boulogne C, Tordo N, Lemichez E, Loiseau PM, Rudel T, Sauvaire D, Cintrat JC, Gillet D, Barbier J.

Sci Rep. 2017 Nov 14;7(1):15567. doi: 10.1038/s41598-017-15466-7.

9.

Antiviral effects of Retro-2cycl and Retro-2.1 against Enterovirus 71 in vitro and in vivo.

Dai W, Wu Y, Bi J, Lu X, Hou A, Zhou Y, Sun B, Kong W, Barbier J, Cintrat JC, Gao F, Gillet D, Su W, Jiang C.

Antiviral Res. 2017 Aug;144:311-321. doi: 10.1016/j.antiviral.2017.07.001. Epub 2017 Jul 5.

PMID:
28688753
10.

[An educational tool for patients with chronic pain].

Gillet D.

Soins. 2017 May;62(815):49-50. doi: 10.1016/j.soin.2017.03.014. French.

11.

Editorial for the special issue of the 1st international conference CBRN Research and Innovation Antibes-Juan-les-Pins (France) March 16-19 2015.

Dorandeu F, Gillet D.

Chem Biol Interact. 2017 Apr 1;267:1. doi: 10.1016/j.cbi.2017.01.023. Epub 2017 Jan 31. No abstract available.

PMID:
28159580
12.

Retro-1 Analogues Differentially Affect Oligonucleotide Delivery and Toxin Trafficking.

Yang B, Ming X, Abdelkafi H, Pons V, Michau A, Gillet D, Cintrat JC, Barbier J, Juliano R.

ChemMedChem. 2016 Nov 21;11(22):2506-2510. doi: 10.1002/cmdc.201600463. Epub 2016 Oct 25.

PMID:
27778487
13.

Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales.

Gupta N, Noël R, Goudet A, Hinsinger K, Michau A, Pons V, Abdelkafi H, Secher T, Shima A, Shtanko O, Sakurai Y, Cojean S, Pomel S, Liévin-Le Moal V, Leignel V, Herweg JA, Fischer A, Johannes L, Harrison K, Beard PM, Clayette P, Le Grand R, Rayner JO, Rudel T, Vacus J, Loiseau PM, Davey RA, Oswald E, Cintrat JC, Barbier J, Gillet D.

Chem Biol Interact. 2017 Apr 1;267:96-103. doi: 10.1016/j.cbi.2016.10.005. Epub 2016 Oct 3.

PMID:
27712998
14.

Vaccinia Virus Uses Retromer-Independent Cellular Retrograde Transport Pathways To Facilitate the Wrapping of Intracellular Mature Virions during Virus Morphogenesis.

Harrison K, Haga IR, Pechenick Jowers T, Jasim S, Cintrat JC, Gillet D, Schmitt-John T, Digard P, Beard PM.

J Virol. 2016 Oct 28;90(22):10120-10132. doi: 10.1128/JVI.01464-16. Print 2016 Nov 15.

15.

Correction: The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH.

Araye A, Goudet A, Barbier J, Pichard S, Baron B, England P, Pérez J, Zinn-Justin S, Chenal A, Gillet D.

PLoS One. 2016 Aug 18;11(8):e0161743. doi: 10.1371/journal.pone.0161743. eCollection 2016.

16.

Immunoadjuvant Properties of the Rho Activating Factor CNF1 in Prophylactic and Curative Vaccination against Leishmania infantum.

Michel G, Ferrua B, Munro P, Boyer L, Mathal N, Gillet D, Marty P, Lemichez E.

PLoS One. 2016 Jun 3;11(6):e0156363. doi: 10.1371/journal.pone.0156363. eCollection 2016.

17.

The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH.

Araye A, Goudet A, Barbier J, Pichard S, Baron B, England P, Pérez J, Zinn-Justin S, Chenal A, Gillet D.

PLoS One. 2016 Apr 12;11(4):e0153401. doi: 10.1371/journal.pone.0153401. eCollection 2016. Erratum in: PLoS One. 2016;11(8):e0161743.

18.

Laboratory Studies of Nonlinear Optical Signals for Caries Detection.

Terrer E, Panayotov IV, Slimani A, Tardivo D, Gillet D, Levallois B, Fejerskov O, Gergely C, Cuisinier FJ, Tassery H, Cloitre T.

J Dent Res. 2016 May;95(5):574-9. doi: 10.1177/0022034516629400. Epub 2016 Jan 29.

PMID:
26826107
19.

Intracellular pathogens convert macrophages from death traps into hospitable homes.

Barbier J, Cintrat JC, Gillet D.

FEBS J. 2016 Feb;283(4):595-7. doi: 10.1111/febs.13657. Epub 2016 Feb 2.

20.

A High Diversity in Chitinolytic and Chitosanolytic Species and Enzymes and Their Oligomeric Products Exist in Soil with a History of Chitin and Chitosan Exposure.

Nampally M, Rajulu MB, Gillet D, Suryanarayanan TS, Moerschbacher BB.

Biomed Res Int. 2015;2015:857639. doi: 10.1155/2015/857639. Epub 2015 Jul 26.

21.

Bee venom phospholipase A2 as a membrane-binding vector for cell surface display or internalization of soluble proteins.

Babon A, Wurceldorf T, Almunia C, Pichard S, Chenal A, Buhot C, Beaumelle B, Gillet D.

Toxicon. 2016 Jun 15;116:56-62. doi: 10.1016/j.toxicon.2015.07.338. Epub 2015 Aug 4.

PMID:
26253725
22.

A versatile in vitro ELISA test for quantification and quality testing of infectious, inactivated and formulated rabies virus used in veterinary monovalent or combination vaccine.

Sigoillot-Claude C, Battaglio M, Fiorucci M, Gillet D, Vimort AS, Giraud Y, Laurent S, Vaganay A, Poulet H.

Vaccine. 2015 Jul 31;33(32):3843-9. doi: 10.1016/j.vaccine.2015.06.091. Epub 2015 Jul 2.

PMID:
26144898
23.

Synthesis, Chiral Separation, Absolute Configuration Assignment, and Biological Activity of Enantiomers of Retro-1 as Potent Inhibitors of Shiga Toxin.

Abdelkafi H, Michau A, Clerget A, Buisson DA, Johannes L, Gillet D, Barbier J, Cintrat JC.

ChemMedChem. 2015 Jul;10(7):1153-6. doi: 10.1002/cmdc.201500139. Epub 2015 Jun 1.

PMID:
26033849
24.

Retrograde Trafficking Inhibitor of Shiga Toxins Reduces Morbidity and Mortality of Mice Infected with Enterohemorrhagic Escherichia coli.

Secher T, Shima A, Hinsinger K, Cintrat JC, Johannes L, Barbier J, Gillet D, Oswald E.

Antimicrob Agents Chemother. 2015 Aug;59(8):5010-3. doi: 10.1128/AAC.00455-15. Epub 2015 May 18.

25.

A therapy parameter-based model for predicting blood glucose concentrations in patients with type 1 diabetes.

Bock A, François G, Gillet D.

Comput Methods Programs Biomed. 2015 Feb;118(2):107-23. doi: 10.1016/j.cmpb.2014.12.002. Epub 2014 Dec 12.

PMID:
25577673
26.

Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction.

Nonnenmacher ME, Cintrat JC, Gillet D, Weber T.

J Virol. 2015 Feb;89(3):1673-87. doi: 10.1128/JVI.02520-14. Epub 2014 Nov 19.

27.

(S)-N-Methyldihydroquinazolinones are the Active Enantiomers of Retro-2 Derived Compounds against Toxins.

Gupta N, Pons V, Noël R, Buisson DA, Michau A, Johannes L, Gillet D, Barbier J, Cintrat JC.

ACS Med Chem Lett. 2013 Dec 4;5(1):94-7. doi: 10.1021/ml400457j. eCollection 2014 Jan 9.

28.

High discordance rates between sub-areolar and peri-tumoural breast lymphoscintigraphy.

Noushi F, Spillane AJ, Uren RF, Cooper R, Allwright S, Snook KL, Gillet D, Pearce AM, Gebski V.

Eur J Surg Oncol. 2013 Oct;39(10):1053-60. doi: 10.1016/j.ejso.2013.06.006. Epub 2013 Jul 18. Erratum in: Eur J Surg Oncol. 2014 Feb;40(2):246.

PMID:
23871572
29.

Bee Venom Phospholipase A2, a Good "Chauffeur" for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1.

Almunia C, Bretaudeau M, Held G, Babon A, Marchetti C, Castelli FA, Ménez A, Maillere B, Gillet D.

PLoS One. 2013 Jun 18;8(6):e67645. doi: 10.1371/journal.pone.0067645. Print 2013.

30.

N-methyldihydroquinazolinone derivatives of Retro-2 with enhanced efficacy against Shiga toxin.

Noel R, Gupta N, Pons V, Goudet A, Garcia-Castillo MD, Michau A, Martinez J, Buisson DA, Johannes L, Gillet D, Barbier J, Cintrat JC.

J Med Chem. 2013 Apr 25;56(8):3404-13. doi: 10.1021/jm4002346. Epub 2013 Apr 5.

PMID:
23517565
31.

The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides.

Ming X, Carver K, Fisher M, Noel R, Cintrat JC, Gillet D, Barbier J, Cao C, Bauman J, Juliano RL.

Nucleic Acids Res. 2013 Apr 1;41(6):3673-87. doi: 10.1093/nar/gkt066. Epub 2013 Feb 8.

32.

Measuring the international spreading of the knowledge produced by French dental master theses.

Gillet D, Bérard A, Faivre O, Sarrazy B.

Eur J Dent Educ. 2013 Feb;17(1):26-9. doi: 10.1111/eje.12003. Epub 2012 Sep 24.

PMID:
23279389
33.

Inhibitors of the cellular trafficking of ricin.

Barbier J, Bouclier C, Johannes L, Gillet D.

Toxins (Basel). 2012 Jan;4(1):15-27. doi: 10.3390/toxins4010015. Epub 2012 Jan 6. Review.

34.

Amyloid fibrils formed by the programmed cell death regulator Bcl-xL.

Chenal A, Vendrely C, Vitrac H, Karst JC, Gonneaud A, Blanchet CE, Pichard S, Garcia E, Salin B, Catty P, Gillet D, Hussy N, Marquette C, Almunia C, Forge V.

J Mol Biol. 2012 Jan 20;415(3):584-99. doi: 10.1016/j.jmb.2011.11.024. Epub 2011 Nov 19.

PMID:
22119486
35.

Adaptation to statins restricts human tumour growth in Nude mice.

Follet J, Rémy L, Hesry V, Simon B, Gillet D, Auvray P, Corcos L, Le Jossic-Corcos C.

BMC Cancer. 2011 Nov 22;11:491. doi: 10.1186/1471-2407-11-491.

36.

Accessibility changes within diphtheria toxin T domain upon membrane penetration probed by hydrogen exchange and mass spectrometry.

Man P, Montagner C, Vitrac H, Kavan D, Pichard S, Gillet D, Forest E, Forge V.

J Mol Biol. 2011 Nov 18;414(1):123-34. doi: 10.1016/j.jmb.2011.09.042. Epub 2011 Oct 1.

PMID:
21986198
37.

Cystic fibrosis transmembrane conductance regulator protein expression in the male excretory duct system during development.

Marcorelles P, Gillet D, Friocourt G, Ledé F, Samaison L, Huguen G, Ferec C.

Hum Pathol. 2012 Mar;43(3):390-7. doi: 10.1016/j.humpath.2011.04.031. Epub 2011 Aug 15.

PMID:
21840567
38.

Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain.

Chassaing A, Pichard S, Araye-Guet A, Barbier J, Forge V, Gillet D.

FEBS J. 2011 Dec;278(23):4516-25. doi: 10.1111/j.1742-4658.2011.08053.x. Epub 2011 Mar 9.

39.

A musculoskeletal shoulder model based on pseudo-inverse and null-space optimization.

Terrier A, Aeberhard M, Michellod Y, Mullhaupt P, Gillet D, Farron A, Pioletti DP.

Med Eng Phys. 2010 Nov;32(9):1050-6. doi: 10.1016/j.medengphy.2010.07.006. Epub 2010 Aug 14.

PMID:
20709589
40.

Inhibition of retrograde transport protects mice from lethal ricin challenge.

Stechmann B, Bai SK, Gobbo E, Lopez R, Merer G, Pinchard S, Panigai L, Tenza D, Raposo G, Beaumelle B, Sauvaire D, Gillet D, Johannes L, Barbier J.

Cell. 2010 Apr 16;141(2):231-42. doi: 10.1016/j.cell.2010.01.043.

41.

Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen/deuterium exchange measurements.

Man P, Montagner C, Vitrac H, Kavan D, Pichard S, Gillet D, Forest E, Forge V.

FEBS J. 2010 Feb;277(3):653-62. doi: 10.1111/j.1742-4658.2009.07511.x. Epub 2009 Dec 29.

42.

Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy.

Chenal A, Prongidi-Fix L, Perier A, Aisenbrey C, Vernier G, Lambotte S, Haertlein M, Dauvergne MT, Fragneto G, Bechinger B, Gillet D, Forge V, Ferrand M.

J Mol Biol. 2009 Sep 4;391(5):872-83. doi: 10.1016/j.jmb.2009.06.061. Epub 2009 Jul 1. Erratum in: J Mol Biol. 2009 Dec 4;394(3):587. Haertlein, Michael [added]; Dauvergne, Marie-Thérèse].

PMID:
19576225
43.

Side chain resonances in static oriented proton-decoupled 15N solid-state NMR spectra of membrane proteins.

Aisenbrey C, Prongidi-Fix L, Chenal A, Gillet D, Bechinger B.

J Am Chem Soc. 2009 May 13;131(18):6340-1. doi: 10.1021/ja900677b.

PMID:
19374351
44.

Membrane Interaction of botulinum neurotoxin A translocation (T) domain. The belt region is a regulatory loop for membrane interaction.

Galloux M, Vitrac H, Montagner C, Raffestin S, Popoff MR, Chenal A, Forge V, Gillet D.

J Biol Chem. 2008 Oct 10;283(41):27668-76. doi: 10.1074/jbc.M802557200. Epub 2008 Aug 7.

45.

Creation of intercellular bonds by anchoring protein ligands to membranes using the diphtheria toxin T domain.

Perier A, Gourier C, Pichard S, Husson J, Lajeunesse E, Babon A, Menez A, Gillet D.

FEBS Lett. 2007 Nov 27;581(28):5480-4. Epub 2007 Nov 6.

46.

Evolution of CFTR protein distribution in lung tissue from normal and CF human fetuses.

Marcorelles P, Montier T, Gillet D, Lagarde N, Ferec C.

Pediatr Pulmonol. 2007 Nov;42(11):1032-40.

PMID:
17902144
47.

Annexin V is directly involved in cystic fibrosis transmembrane conductance regulator's chloride channel function.

Trouvé P, Le Drévo MA, Kerbiriou M, Friocourt G, Fichou Y, Gillet D, Férec C.

Biochim Biophys Acta. 2007 Oct;1772(10):1121-33. Epub 2007 Aug 11.

48.
49.

Concerted protonation of key histidines triggers membrane interaction of the diphtheria toxin T domain.

Perier A, Chassaing A, Raffestin S, Pichard S, Masella M, Ménez A, Forge V, Chenal A, Gillet D.

J Biol Chem. 2007 Aug 17;282(33):24239-45. Epub 2007 Jun 21.

50.

Behavior of the N-terminal helices of the diphtheria toxin T domain during the successive steps of membrane interaction.

Montagner C, Perier A, Pichard S, Vernier G, Ménez A, Gillet D, Forge V, Chenal A.

Biochemistry. 2007 Feb 20;46(7):1878-87. Epub 2007 Jan 24.

PMID:
17249698

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