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Items: 29

1.

Mass spectrometry for small molecule pharmaceutical product development: a review.

Gillespie TA, Winger BE.

Mass Spectrom Rev. 2011 May-Jun;30(3):479-90. doi: 10.1002/mas.20289. Epub 2010 Dec 22. Review.

PMID:
21500245
2.

Identification and counting of carbonyl and hydroxyl functionalities in protonated bifunctional analytes by using solution derivatization prior to mass spectrometric analysis via ion-molecule reactions.

Somuramasami J, Winger BE, Gillespie TA, Kenttämaa HI.

J Am Soc Mass Spectrom. 2010 May;21(5):773-84. doi: 10.1016/j.jasms.2009.11.008. Epub 2009 Dec 4.

3.

Identification of aliphatic and aromatic tertiary N-oxide functionalities in protonated analytes via ion/molecule and dissociation reactions in an FT-ICR mass spectrometer.

Duan P, Fu M, Gillespie TA, Winger BE, Kenttämaa HI.

J Org Chem. 2009 Feb 6;74(3):1114-23. doi: 10.1021/jo802001e.

PMID:
19133762
4.

Identification of the aromatic tertiary N-oxide functionality in protonated analytes via ion/molecule reactions in mass spectrometers.

Duan P, Gillespie TA, Winger BE, Kenttämaa HI.

J Org Chem. 2008 Jul 4;73(13):4888-94. doi: 10.1021/jo800309u. Epub 2008 Jun 4.

PMID:
18522416
5.

Disposition and metabolic fate of prasugrel in mice, rats, and dogs.

Smith RL, Gillespie TA, Rash TJ, Kurihara A, Farid NA.

Xenobiotica. 2007 Aug;37(8):884-901.

PMID:
17701835
6.

The disposition of prasugrel, a novel thienopyridine, in humans.

Farid NA, Smith RL, Gillespie TA, Rash TJ, Blair PE, Kurihara A, Goldberg MJ.

Drug Metab Dispos. 2007 Jul;35(7):1096-104. Epub 2007 Apr 2.

PMID:
17403916
7.

A review of nanoelectrospray ionization applications for drug metabolism and pharmacokinetics.

Wickremsinhe ER, Singh G, Ackermann BL, Gillespie TA, Chaudhary AK.

Curr Drug Metab. 2006 Dec;7(8):913-28. Review.

PMID:
17168691
8.

The disposition and metabolism of naveglitazar, a peroxisome proliferator-activated receptor alpha-gamma dual, gamma-dominant agonist in mice, rats, and monkeys.

Yi P, Hadden CE, Annes WF, Jackson DA, Peterson BC, Gillespie TA, Johnson JT.

Drug Metab Dispos. 2007 Jan;35(1):51-61. Epub 2006 Sep 29.

PMID:
17012539
9.

Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry.

Khatib-Shahidi S, Andersson M, Herman JL, Gillespie TA, Caprioli RM.

Anal Chem. 2006 Sep 15;78(18):6448-56.

PMID:
16970320
10.
11.

Pergolide: multiple-dose pharmacokinetics in patients with mild to moderate Parkinson disease.

Thalamas C, Rajman I, Kulisevsky J, Lledó A, Mackie AE, Blin O, Gillespie TA, Seger M, Rascol O.

Clin Neuropharmacol. 2005 May-Jun;28(3):120-5. Erratum in: Clin Neuropharmacol. 2005 Sep-Oct;28(5):254.

PMID:
15965310
12.

Synthesis and biological activity of some known and putative duloxetine metabolites.

Kuo F, Gillespie TA, Kulanthaivel P, Lantz RJ, Ma TW, Nelson DL, Threlkeld PG, Wheeler WJ, Yi P, Zmijewski M.

Bioorg Med Chem Lett. 2004 Jul 5;14(13):3481-6. Erratum in: Bioorg Med Chem Lett. 2004 Oct 18;14(20):5233.

PMID:
15177457
13.

Metabolism, excretion, and pharmacokinetics of duloxetine in healthy human subjects.

Lantz RJ, Gillespie TA, Rash TJ, Kuo F, Skinner M, Kuan HY, Knadler MP.

Drug Metab Dispos. 2003 Sep;31(9):1142-50.

PMID:
12920170
14.

Eradication of a resistant Pseudomonas aeruginosa strain after a cluster of infections in a hematology/oncology unit.

Gillespie TA, Johnson PR, Notman AW, Coia JE, Hanson MF.

Clin Microbiol Infect. 2000 Mar;6(3):125-30.

15.

Bacterial contamination of children's toys used in a general practitioner's surgery.

McKay I, Gillespie TA.

Scott Med J. 2000 Feb;45(1):12-3.

PMID:
10765527
16.

Characterization of olanzapine (LY170053) in human liver slices by liquid chromatography/tandem mass spectrometry.

Murphy AT, Lake BG, Bernstein JR, Franklin RB, Gillespie TA.

J Mass Spectrom. 1998 Dec;33(12):1237-45.

PMID:
9875525
17.

Three-dimensional quantitative structure activity relationship analyses of substrates for CYP2B6.

Ekins S, Bravi G, Ring BJ, Gillespie TA, Gillespie JS, Vandenbranden M, Wrighton SA, Wikel JH.

J Pharmacol Exp Ther. 1999 Jan;288(1):21-9.

PMID:
9862748
18.

Development of an instrument to measure cardiac illness dependency.

Riegel B, Glaser D, Thomas V, Gocka I, Gillespie TA.

Heart Lung. 1997 Nov-Dec;26(6):448-57.

PMID:
9431491
19.
21.
22.

Analysis of olanzapine in human plasma utilizing reversed-phase high-performance liquid chromatography with electrochemical detection.

Catlow JT, Barton RD, Clemens M, Gillespie TA, Goodwin M, Swanson SP.

J Chromatogr B Biomed Appl. 1995 Jun 9;668(1):85-90.

PMID:
7550985
23.

Determination of xanomeline in human plasma by ion-spray tandem mass spectrometry.

Murphy AT, Bonate PL, Kasper SC, Gillespie TA, DeLong AF.

Biol Mass Spectrom. 1994 Oct;23(10):621-5.

PMID:
7986832
24.

Determination of dolasetron and its reduced metabolite in human plasma by GC-MS and LC.

Gillespie TA, Eckstein JA, Nardella P, Coutant JE.

J Pharm Biomed Anal. 1993 Oct;11(10):955-62.

PMID:
8305600
25.

Differences in the low-energy collision-activated dissociation of carboxylate anions from structurally similar prostaglandins: E2, F 2α, D 2, and DHKF 2α.

Gillespie TA, Yost RA.

J Am Soc Mass Spectrom. 1990 Sep;1(5):389-96. doi: 10.1016/1044-0305(90)85019-I.

PMID:
24248901
26.

Purification and quantification of arachidonate metabolites: critical evaluation of methods and interpretation of results.

Wu-Wang CY, Neu J, Gillespie TA, Yost RA.

Semin Perinatol. 1986 Oct;10(4):255-69. No abstract available.

PMID:
3105065
27.

Effects of external counterpulsation on enzymatically estimated infarct size and ventricular arrhythmia.

Gowda SK, Gillespie TA, Byrne JD, Ambos HD, Sobel BE, Roberts R.

Br Heart J. 1978 Mar;40(3):308-14. No abstract available.

28.

Effects of dobutamine in patients with acute myocardial infarction.

Gillespie TA, Ambos HD, Sobel BE, Roberts R.

Am J Cardiol. 1977 Apr;39(4):588-94.

PMID:
848445
29.

A rationale for therapy of acute myocardial infarction: limitation of infarct size.

Gillespie TA, Sobel BE.

Adv Intern Med. 1977;22:319-53. Review. No abstract available.

PMID:
14484

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