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Items: 1 to 50 of 103

1.

Disruption of the SucT acyltransferase in Mycobacterium smegmatis abrogates succinylation of cell envelope polysaccharides.

Palčeková Z, Angala SK, Belardinelli JM, Eskandarian HA, Joe M, Brunton R, Rithner C, Jones V, Nigou J, Lowary TL, Gilleron M, McNeil M, Jackson M.

J Biol Chem. 2019 Jun 28;294(26):10325-10335. doi: 10.1074/jbc.RA119.008585. Epub 2019 May 20.

PMID:
31110045
2.

The flip-flap puzzle flap: Another recycling option.

Gandolfi S, Carloni R, Gilleron M, Bonmarchand A, Auquit-Auckbur I.

Arch Plast Surg. 2019 Mar;46(2):176-180. doi: 10.5999/aps.2018.00983. Epub 2019 Mar 31.

3.

Interactions of domain antibody (dAbκ11) with Mycobacterium tuberculosis Ac2SGL in complex with CD1b.

Law CT, Camacho F, Garcia-Alles LF, Gilleron M, Sarmiento ME, Norazmi MN, Acosta A, Choong YS.

Tuberculosis (Edinb). 2019 Jan;114:9-16. doi: 10.1016/j.tube.2018.11.002. Epub 2018 Nov 4.

PMID:
30711162
4.

Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells.

Gharun K, Senges J, Seidl M, Lösslein A, Kolter J, Lohrmann F, Fliegauf M, Elgizouli M, Alber M, Vavra M, Schachtrup K, Illert AL, Gilleron M, Kirschning CJ, Triantafyllopoulou A, Henneke P.

EMBO Rep. 2018 Dec;19(12). pii: e47190. doi: 10.15252/embr.201847190. No abstract available.

5.

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2.

Decout A, Silva-Gomes S, Drocourt D, Blattes E, Rivière M, Prandi J, Larrouy-Maumus G, Caminade AM, Hamasur B, Källenius G, Kaur D, Dobos KM, Lucas M, Sutcliffe IC, Besra GS, Appelmelk BJ, Gilleron M, Jackson M, Vercellone A, Tiraby G, Nigou J.

Sci Rep. 2018 Nov 15;8(1):16840. doi: 10.1038/s41598-018-35393-5.

6.

CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis.

James CA, Yu KKQ, Gilleron M, Prandi J, Yedulla VR, Moleda ZZ, Diamanti E, Khan M, Aggarwal VK, Reijneveld JF, Reinink P, Lenz S, Emerson RO, Scriba TJ, Souter MNT, Godfrey DI, Pellicci DG, Moody DB, Minnaard AJ, Seshadri C, Van Rhijn I.

Cell Chem Biol. 2018 Apr 19;25(4):392-402.e14. doi: 10.1016/j.chembiol.2018.01.006. Epub 2018 Feb 1.

7.

The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria.

Tersa M, Raich L, Albesa-Jové D, Trastoy B, Prandi J, Gilleron M, Rovira C, Guerin ME.

ACS Chem Biol. 2018 Jan 19;13(1):131-140. doi: 10.1021/acschembio.7b00578. Epub 2017 Dec 11.

PMID:
29185694
8.

Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells.

Gharun K, Senges J, Seidl M, Lösslein A, Kolter J, Lohrmann F, Fliegauf M, Elgizouli M, Alber M, Vavra M, Schachtrup K, Illert AL, Gilleron M, Kirschning CJ, Triantafyllopoulou A, Henneke P.

EMBO Rep. 2017 Dec;18(12):2144-2159. doi: 10.15252/embr.201744121. Epub 2017 Nov 2. Erratum in: EMBO Rep. 2018 Dec;19(12):.

9.

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids.

Blanc L, Gilleron M, Prandi J, Song OR, Jang MS, Gicquel B, Drocourt D, Neyrolles O, Brodin P, Tiraby G, Vercellone A, Nigou J.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11205-11210. doi: 10.1073/pnas.1707840114. Epub 2017 Oct 2.

10.

Rational design of adjuvants targeting the C-type lectin Mincle.

Decout A, Silva-Gomes S, Drocourt D, Barbe S, André I, Cueto FJ, Lioux T, Sancho D, Pérouzel E, Vercellone A, Prandi J, Gilleron M, Tiraby G, Nigou J.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2675-2680. doi: 10.1073/pnas.1612421114. Epub 2017 Feb 21.

11.

Protective efficacy of a lipid antigen vaccine in a guinea pig model of tuberculosis.

Larrouy-Maumus G, Layre E, Clark S, Prandi J, Rayner E, Lepore M, de Libero G, Williams A, Puzo G, Gilleron M.

Vaccine. 2017 Mar 7;35(10):1395-1402. doi: 10.1016/j.vaccine.2017.01.079. Epub 2017 Feb 9.

PMID:
28190740
12.

Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in Mycobacterium tuberculosis.

Angala SK, McNeil MR, Shi L, Joe M, Pham H, Zuberogoitia S, Nigou J, Boot CM, Lowary TL, Gilleron M, Jackson M.

ACS Chem Biol. 2017 Mar 17;12(3):682-691. doi: 10.1021/acschembio.6b01071. Epub 2017 Jan 20.

13.

Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens.

Gilleron M, Lepore M, Layre E, Cala-De Paepe D, Mebarek N, Shayman JA, Canaan S, Mori L, Carrière F, Puzo G, De Libero G.

Cell Chem Biol. 2016 Sep 22;23(9):1147-1156. doi: 10.1016/j.chembiol.2016.07.021.

14.

QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease.

Guarani V, Jardel C, Chrétien D, Lombès A, Bénit P, Labasse C, Lacène E, Bourillon A, Imbard A, Benoist JF, Dorboz I, Gilleron M, Goetzman ES, Gaignard P, Slama A, Elmaleh-Bergès M, Romero NB, Rustin P, Ogier de Baulny H, Paulo JA, Harper JW, Schiff M.

Elife. 2016 Sep 13;5. pii: e17163. doi: 10.7554/eLife.17163.

15.

Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization.

Barthe P, Veyron-Churlet R, de Visch A, Gilleron M, Saliou JM, Tomavo S, Nigou J, Brodin P, Cohen-Gonsaud M.

Structure. 2016 Oct 4;24(10):1788-1794. doi: 10.1016/j.str.2016.07.009. Epub 2016 Aug 25.

16.

Selection of phage-displayed human antibody fragments specific for CD1b presenting the Mycobacterium tuberculosis glycolipid Ac2SGL.

Camacho F, Sarmiento ME, Reyes F, Kim L, Huggett J, Lepore M, Otero O, Gilleron M, Puzo G, Norazmi MN, Rook G, Mori L, De Libero G, Acosta A.

Int J Mycobacteriol. 2016 Jun;5(2):120-7. doi: 10.1016/j.ijmyco.2015.12.002. Epub 2016 Feb 17.

17.

Severe respiratory complex III defect prevents liver adaptation to prolonged fasting.

Kremer LS, L'hermitte-Stead C, Lesimple P, Gilleron M, Filaut S, Jardel C, Haack TB, Strom TM, Meitinger T, Azzouz H, Tebib N, Ogier de Baulny H, Touati G, Prokisch H, Lombès A.

J Hepatol. 2016 Aug;65(2):377-85. doi: 10.1016/j.jhep.2016.04.017. Epub 2016 May 2.

18.

BCG Vaccination Induces Robust CD4+ T Cell Responses to Mycobacterium tuberculosis Complex-Specific Lipopeptides in Guinea Pigs.

Kaufmann E, Spohr C, Battenfeld S, De Paepe D, Holzhauser T, Balks E, Homolka S, Reiling N, Gilleron M, Bastian M.

J Immunol. 2016 Mar 15;196(6):2723-32. doi: 10.4049/jimmunol.1502307. Epub 2016 Feb 17.

19.

T Cell Responses against Mycobacterial Lipids and Proteins Are Poorly Correlated in South African Adolescents.

Seshadri C, Lin L, Scriba TJ, Peterson G, Freidrich D, Frahm N, DeRosa SC, Moody DB, Prandi J, Gilleron M, Mahomed H, Jiang W, Finak G, Hanekom WA, Gottardo R, McElrath MJ, Hawn TR.

J Immunol. 2015 Nov 15;195(10):4595-603. doi: 10.4049/jimmunol.1501285. Epub 2015 Oct 14.

20.

Ac2PIM-responsive miR-150 and miR-143 target receptor-interacting protein kinase 2 and transforming growth factor beta-activated kinase 1 to suppress NOD2-induced immunomodulators.

Prakhar P, Holla S, Ghorpade DS, Gilleron M, Puzo G, Udupa V, Balaji KN.

J Biol Chem. 2015 Oct 30;290(44):26576-86. doi: 10.1074/jbc.M115.662817. Epub 2015 Sep 21.

21.

A glycomic approach reveals a new mycobacterial polysaccharide.

Larrouy-Maumus G, Gilleron M, Skovierová H, Zuberogoitia S, Brennan PJ, Puzo G, Jackson M, Nigou J.

Glycobiology. 2015 Nov;25(11):1163-71. doi: 10.1093/glycob/cwv061. Epub 2015 Aug 10.

22.

Manipulation of the endocytic pathway and phagocyte functions by Mycobacterium tuberculosis lipoarabinomannan.

Vergne I, Gilleron M, Nigou J.

Front Cell Infect Microbiol. 2015 Jan 12;4:187. doi: 10.3389/fcimb.2014.00187. eCollection 2014. Review.

23.

A diagnostic flow chart for POLG-related diseases based on signs sensitivity and specificity.

Tchikviladzé M, Gilleron M, Maisonobe T, Galanaud D, Laforêt P, Durr A, Eymard B, Mochel F, Ogier H, Béhin A, Stojkovic T, Degos B, Gourfinkel-An I, Sedel F, Anheim M, Elbaz A, Viala K, Vidailhet M, Brice A, Jardel C, Lombès A.

J Neurol Neurosurg Psychiatry. 2015 Jun;86(6):646-54. doi: 10.1136/jnnp-2013-306799. Epub 2014 Aug 11.

PMID:
25118206
24.

Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues: chain length is essential for high antigenicity.

Gau B, Lemétais A, Lepore M, Garcia-Alles LF, Bourdreux Y, Mori L, Gilleron M, De Libero G, Puzo G, Beau JM, Prandi J.

Chembiochem. 2013 Dec 16;14(18):2413-7. doi: 10.1002/cbic.201300482. Epub 2013 Oct 31. No abstract available.

PMID:
24174158
25.

Unsolved issues related to human mitochondrial diseases.

Lombès A, Auré K, Bellanné-Chantelot C, Gilleron M, Jardel C.

Biochimie. 2014 May;100:171-6. doi: 10.1016/j.biochi.2013.08.012. Epub 2013 Aug 20. Review.

26.

Mutations in CYC1, encoding cytochrome c1 subunit of respiratory chain complex III, cause insulin-responsive hyperglycemia.

Gaignard P, Menezes M, Schiff M, Bayot A, Rak M, Ogier de Baulny H, Su CH, Gilleron M, Lombes A, Abida H, Tzagoloff A, Riley L, Cooper ST, Mina K, Sivadorai P, Davis MR, Allcock RJ, Kresoje N, Laing NG, Thorburn DR, Slama A, Christodoulou J, Rustin P.

Am J Hum Genet. 2013 Aug 8;93(2):384-9. doi: 10.1016/j.ajhg.2013.06.015. Epub 2013 Aug 1.

27.

Prevalence of rare mitochondrial DNA mutations in mitochondrial disorders.

Bannwarth S, Procaccio V, Lebre AS, Jardel C, Chaussenot A, Hoarau C, Maoulida H, Charrier N, Gai X, Xie HM, Ferre M, Fragaki K, Hardy G, Mousson de Camaret B, Marlin S, Dhaenens CM, Slama A, Rocher C, Paul Bonnefont J, Rötig A, Aoutil N, Gilleron M, Desquiret-Dumas V, Reynier P, Ceresuela J, Jonard L, Devos A, Espil-Taris C, Martinez D, Gaignard P, Le Quan Sang KH, Amati-Bonneau P, Falk MJ, Florentz C, Chabrol B, Durand-Zaleski I, Paquis-Flucklinger V.

J Med Genet. 2013 Oct;50(10):704-14. doi: 10.1136/jmedgenet-2013-101604. Epub 2013 Jul 11.

28.

Tuberculosis 2012: biology, pathogenesis and intervention strategies; an update from the city of light.

Gouzy A, Nigou J, Gilleron M, Neyrolles O, Tailleux L, Gordon SV.

Res Microbiol. 2013 Apr;164(3):270-80. doi: 10.1016/j.resmic.2012.12.006. Epub 2012 Dec 20.

PMID:
23266372
29.

Analysis of the chromosome X exome in patients with autism spectrum disorders identified novel candidate genes, including TMLHE.

Nava C, Lamari F, Héron D, Mignot C, Rastetter A, Keren B, Cohen D, Faudet A, Bouteiller D, Gilleron M, Jacquette A, Whalen S, Afenjar A, Périsse D, Laurent C, Dupuits C, Gautier C, Gérard M, Huguet G, Caillet S, Leheup B, Leboyer M, Gillberg C, Delorme R, Bourgeron T, Brice A, Depienne C.

Transl Psychiatry. 2012 Oct 23;2:e179. doi: 10.1038/tp.2012.102.

30.

A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria.

Larrouy-Maumus G, Škovierová H, Dhouib R, Angala SK, Zuberogoitia S, Pham H, Villela AD, Mikušová K, Noguera A, Gilleron M, Valentínová L, Korduláková J, Brennan PJ, Puzo G, Nigou J, Jackson M.

J Biol Chem. 2012 Nov 16;287(47):39933-41. doi: 10.1074/jbc.M112.400986. Epub 2012 Oct 4.

31.

Deciphering the role of CD1e protein in mycobacterial phosphatidyl-myo-inositol mannosides (PIM) processing for presentation by CD1b to T lymphocytes.

Cala-De Paepe D, Layre E, Giacometti G, Garcia-Alles LF, Mori L, Hanau D, de Libero G, de la Salle H, Puzo G, Gilleron M.

J Biol Chem. 2012 Sep 7;287(37):31494-502. doi: 10.1074/jbc.M112.386300. Epub 2012 Jul 10.

32.

Bacterial cell wall macroamphiphiles: pathogen-/microbe-associated molecular patterns detected by mammalian innate immune system.

Ray A, Cot M, Puzo G, Gilleron M, Nigou J.

Biochimie. 2013 Jan;95(1):33-42. doi: 10.1016/j.biochi.2012.06.007. Epub 2012 Jun 15. Review.

PMID:
22706280
33.

Lipoglycans contribute to innate immune detection of mycobacteria.

Krishna S, Ray A, Dubey SK, Larrouy-Maumus G, Chalut C, Castanier R, Noguera A, Gilleron M, Puzo G, Vercellone A, Nampoothiri KM, Nigou J.

PLoS One. 2011;6(12):e28476. doi: 10.1371/journal.pone.0028476. Epub 2011 Dec 2.

34.

Lipoteichoic acid in Streptomyces hygroscopicus: structural model and immunomodulatory activities.

Cot M, Ray A, Gilleron M, Vercellone A, Larrouy-Maumus G, Armau E, Gauthier S, Tiraby G, Puzo G, Nigou J.

PLoS One. 2011;6(10):e26316. doi: 10.1371/journal.pone.0026316. Epub 2011 Oct 18.

35.

Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids.

Garcia-Alles LF, Collmann A, Versluis C, Lindner B, Guiard J, Maveyraud L, Huc E, Im JS, Sansano S, Brando T, Julien S, Prandi J, Gilleron M, Porcelli SA, de la Salle H, Heck AJ, Mori L, Puzo G, Mourey L, De Libero G.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17755-60. doi: 10.1073/pnas.1110118108. Epub 2011 Oct 17.

36.

Fine tuning by human CD1e of lipid-specific immune responses.

Facciotti F, Cavallari M, Angénieux C, Garcia-Alles LF, Signorino-Gelo F, Angman L, Gilleron M, Prandi J, Puzo G, Panza L, Xia C, Wang PG, Dellabona P, Casorati G, Porcelli SA, de la Salle H, Mori L, De Libero G.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14228-33. doi: 10.1073/pnas.1108809108. Epub 2011 Aug 15.

37.

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes.

Garcia-Alles LF, Giacometti G, Versluis C, Maveyraud L, de Paepe D, Guiard J, Tranier S, Gilleron M, Prandi J, Hanau D, Heck AJ, Mori L, De Libero G, Puzo G, Mourey L, de la Salle H.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13230-5. doi: 10.1073/pnas.1105627108. Epub 2011 Jul 25.

38.

Membrane-associated DegP in Bordetella chaperones a repeat-rich secretory protein.

Baud C, Gutsche I, Willery E, de Paepe D, Drobecq H, Gilleron M, Locht C, Jamin M, Jacob-Dubuisson F.

Mol Microbiol. 2011 Jun;80(6):1625-36. doi: 10.1111/j.1365-2958.2011.07672.x. Epub 2011 May 12.

39.

Deciphering sulfoglycolipids of Mycobacterium tuberculosis.

Layre E, Paepe DC, Larrouy-Maumus G, Vaubourgeix J, Mundayoor S, Lindner B, Puzo G, Gilleron M.

J Lipid Res. 2011 Jun;52(6):1098-110. doi: 10.1194/jlr.M013482. Epub 2011 Apr 11.

40.

Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis.

Skovierová H, Larrouy-Maumus G, Pham H, Belanová M, Barilone N, Dasgupta A, Mikusová K, Gicquel B, Gilleron M, Brennan PJ, Puzo G, Nigou J, Jackson M.

J Biol Chem. 2010 Dec 31;285(53):41348-55. doi: 10.1074/jbc.M110.188110. Epub 2010 Oct 28.

41.

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling.

Brodin P, Poquet Y, Levillain F, Peguillet I, Larrouy-Maumus G, Gilleron M, Ewann F, Christophe T, Fenistein D, Jang J, Jang MS, Park SJ, Rauzier J, Carralot JP, Shrimpton R, Genovesio A, Gonzalo-Asensio JA, Puzo G, Martin C, Brosch R, Stewart GR, Gicquel B, Neyrolles O.

PLoS Pathog. 2010 Sep 9;6(9):e1001100. doi: 10.1371/journal.ppat.1001100.

42.

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan.

Driessen NN, Stoop EJ, Ummels R, Gurcha SS, Mishra AK, Larrouy-Maumus G, Nigou J, Gilleron M, Puzo G, Maaskant JJ, Sparrius M, Besra GS, Bitter W, Vandenbroucke-Grauls CM, Appelmelk BJ.

Microbiology. 2010 Nov;156(Pt 11):3492-502. doi: 10.1099/mic.0.037507-0. Epub 2010 Aug 5.

43.

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ.

Jang J, Stella A, Boudou F, Levillain F, Darthuy E, Vaubourgeix J, Wang C, Bardou F, Puzo G, Gilleron M, Burlet-Schiltz O, Monsarrat B, Brodin P, Gicquel B, Neyrolles O.

Microbiology. 2010 Jun;156(Pt 6):1619-31. doi: 10.1099/mic.0.038133-0. Epub 2010 Feb 25.

PMID:
20185505
44.

Mini-invasive nail versus DHS to fix pertrochanteric fractures: a case-control study.

Foulongne E, Gilleron M, Roussignol X, Lenoble E, Dujardin F.

Orthop Traumatol Surg Res. 2009 Dec;95(8):592-8. doi: 10.1016/j.otsr.2009.08.007.

45.

NADPH oxidases participate to doxorubicin-induced cardiac myocyte apoptosis.

Gilleron M, Marechal X, Montaigne D, Franczak J, Neviere R, Lancel S.

Biochem Biophys Res Commun. 2009 Oct 30;388(4):727-31. doi: 10.1016/j.bbrc.2009.08.085. Epub 2009 Aug 20.

PMID:
19699179
46.

AftD, a novel essential arabinofuranosyltransferase from mycobacteria.

Skovierová H, Larrouy-Maumus G, Zhang J, Kaur D, Barilone N, Korduláková J, Gilleron M, Guadagnini S, Belanová M, Prevost MC, Gicquel B, Puzo G, Chatterjee D, Brennan PJ, Nigou J, Jackson M.

Glycobiology. 2009 Nov;19(11):1235-47. doi: 10.1093/glycob/cwp116. Epub 2009 Aug 4.

47.

SOCS3 expression induced by PIM2 requires PKC and PI3K signaling.

Narayana Y, Bansal K, Sinha AY, Kapoor N, Puzo G, Gilleron M, Balaji KN.

Mol Immunol. 2009 Sep;46(15):2947-54. doi: 10.1016/j.molimm.2009.06.019. Epub 2009 Jul 15.

PMID:
19608279
48.

Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression.

Doz E, Rose S, Court N, Front S, Vasseur V, Charron S, Gilleron M, Puzo G, Fremaux I, Delneste Y, Erard F, Ryffel B, Martin OR, Quesniaux VF.

J Biol Chem. 2009 Aug 28;284(35):23187-96. doi: 10.1074/jbc.M109.037846. Epub 2009 Jun 26.

49.

Fatty acyl structures of mycobacterium tuberculosis sulfoglycolipid govern T cell response.

Guiard J, Collmann A, Garcia-Alles LF, Mourey L, Brando T, Mori L, Gilleron M, Prandi J, De Libero G, Puzo G.

J Immunol. 2009 Jun 1;182(11):7030-7. doi: 10.4049/jimmunol.0804044.

50.

PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signaling.

Bansal K, Kapoor N, Narayana Y, Puzo G, Gilleron M, Balaji KN.

PLoS One. 2009;4(3):e4911. doi: 10.1371/journal.pone.0004911. Epub 2009 Mar 17.

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