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Items: 47


Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance.

Gilleron J, Bouget G, Ivanov S, Meziat C, Ceppo F, Vergoni B, Djedaini M, Soprani A, Dumas K, Jacquel A, Yvan-Charvet L, Venteclef N, Tanti JF, Cormont M.

Cell Rep. 2018 Dec 18;25(12):3329-3341.e5. doi: 10.1016/j.celrep.2018.11.083.


A common African variant of human connexin 37 is associated with Caucasian primary ovarian insufficiency and has a deleterious effect in vitro.

Bachelot A, Gilleron J, Meduri G, Guberto M, Dulon J, Boucherie S, Touraine P, Misrahi M.

Int J Mol Med. 2018 Feb;41(2):640-648. doi: 10.3892/ijmm.2017.3257. Epub 2017 Nov 16.


Essential and selective role of SNX12 in transport of endocytic and retrograde cargo.

Priya A, Sugatha J, Parveen S, Lacas-Gervais S, Raj P, Gilleron J, Datta S.

J Cell Sci. 2017 Aug 15;130(16):2707-2721. doi: 10.1242/jcs.201905. Epub 2017 Jul 13.


The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells.

Loubiere C, Clavel S, Gilleron J, Harisseh R, Fauconnier J, Ben-Sahra I, Kaminski L, Laurent K, Herkenne S, Lacas-Gervais S, Ambrosetti D, Alcor D, Rocchi S, Cormont M, Michiels JF, Mari B, Mazure NM, Scorrano L, Lacampagne A, Gharib A, Tanti JF, Bost F.

Sci Rep. 2017 Jul 11;7(1):5040. doi: 10.1038/s41598-017-05052-2.


Multiple and complex influences of connexins and pannexins on cell death.

Gilleron J, Carette D, Segretain D, Pointis G.

Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):182-191. doi: 10.1016/j.bbamem.2017.06.004. Epub 2017 Jun 15. Review.


Effects of low doses of carbendazim or iprodione either separately or in mixture on the pubertal rat seminiferous epithelium: An ex vivo study.

Durand P, Martin G, Blondet A, Gilleron J, Carette D, Janczarski S, Christin E, Pointis G, Perrard MH.

Toxicol In Vitro. 2017 Dec;45(Pt 3):366-373. doi: 10.1016/j.tiv.2017.05.022. Epub 2017 May 30.


Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism.

Nicolas S, Blasco-Baque V, Fournel A, Gilleron J, Klopp P, Waget A, Ceppo F, Marlin A, Padmanabhan R, Iacovoni JS, Tercé F, Cani PD, Tanti JF, Burcelin R, Knauf C, Cormont M, Serino M.

Mol Syst Biol. 2017 Mar 16;13(3):921. doi: 10.15252/msb.20167356.


BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice.

Hamouda MA, Jacquel A, Robert G, Puissant A, Richez V, Cassel R, Fenouille N, Roulland S, Gilleron J, Griessinger E, Dubois A, Bailly-Maitre B, Goncalves D, Mallavialle A, Colosetti P, Marchetti S, Amiot M, Gomez-Bougie P, Rochet N, Deckert M, Avet-Loiseau H, Hofman P, Karsenti JM, Jeandel PY, Blin-Wakkach C, Nadel B, Cluzeau T, Anderson KC, Fuzibet JG, Auberger P, Luciano F.

J Exp Med. 2016 Aug 22;213(9):1705-22. doi: 10.1084/jem.20150983. Epub 2016 Jul 25.


DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes.

Vergoni B, Cornejo PJ, Gilleron J, Djedaini M, Ceppo F, Jacquel A, Bouget G, Ginet C, Gonzalez T, Maillet J, Dhennin V, Verbanck M, Auberger P, Froguel P, Tanti JF, Cormont M.

Diabetes. 2016 Oct;65(10):3062-74. doi: 10.2337/db16-0014. Epub 2016 Jul 7.


Ultrastructural localization and distribution of Nardilysin in mammalian male germ cells.

Segretain D, Gilleron J, Bacro JN, Di Marco M, Carette D, Pointis G.

Basic Clin Androl. 2016 Apr 5;26:5. doi: 10.1186/s12610-016-0032-9. eCollection 2016.


Identification of siRNA delivery enhancers by a chemical library screen.

Gilleron J, Paramasivam P, Zeigerer A, Querbes W, Marsico G, Andree C, Seifert S, Amaya P, Stöter M, Koteliansky V, Waldmann H, Fitzgerald K, Kalaidzidis Y, Akinc A, Maier MA, Manoharan M, Bickle M, Zerial M.

Nucleic Acids Res. 2015 Sep 18;43(16):7984-8001. doi: 10.1093/nar/gkv762. Epub 2015 Jul 28.


Physiological roles of connexins and pannexins in reproductive organs.

Kibschull M, Gellhaus A, Carette D, Segretain D, Pointis G, Gilleron J.

Cell Mol Life Sci. 2015 Aug;72(15):2879-98. doi: 10.1007/s00018-015-1965-4. Epub 2015 Jun 23. Review.


Regulation of liver metabolism by the endosomal GTPase Rab5.

Zeigerer A, Bogorad RL, Sharma K, Gilleron J, Seifert S, Sales S, Berndt N, Bulik S, Marsico G, D'Souza RCJ, Lakshmanaperumal N, Meganathan K, Natarajan K, Sachinidis A, Dahl A, Holzhütter HG, Shevchenko A, Mann M, Koteliansky V, Zerial M.

Cell Rep. 2015 May 12;11(6):884-892. doi: 10.1016/j.celrep.2015.04.018. Epub 2015 Apr 30.


New cellular mechanisms of gap junction degradation and recycling.

Carette D, Gilleron J, Denizot JP, Grant K, Pointis G, Segretain D.

Biol Cell. 2015 Jul;107(7):218-31. doi: 10.1111/boc.201400048. Epub 2015 May 6.


Connexin a check-point component of cell apoptosis in normal and physiopathological conditions.

Carette D, Gilleron J, Chevallier D, Segretain D, Pointis G.

Biochimie. 2014 Jun;101:1-9. doi: 10.1016/j.biochi.2013.11.015. Epub 2013 Dec 1. Review.


Rab4b controls an early endosome sorting event by interacting with the γ-subunit of the clathrin adaptor complex 1.

Perrin L, Lacas-Gervais S, Gilleron J, Ceppo F, Prodon F, Benmerah A, Tanti JF, Cormont M.

J Cell Sci. 2013 Nov 1;126(Pt 21):4950-62. doi: 10.1242/jcs.130575. Epub 2013 Sep 4. Erratum in: J Cell Sci. 2014 Jan 1;127(Pt 1):258. Laura, Perrin [corrected to Perrin, Laura]; Sandra, Lacas-Gervais [corrected to Lacas-Gervais, Sandra]; Jérôme, Gilleron [corrected to Gilleron, Jérôme]; Franck, Ceppo [corrected to Ceppo, Franck]; François, Prodon [corrected to Prodon, François]; Al.


The emerging role of connexin 43 in testis pathogenesis.

Chevallier D, Carette D, Gilleron J, Segretain D, Pointis G.

Curr Mol Med. 2013 Sep;13(8):1331-44. Review.


Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape.

Gilleron J, Querbes W, Zeigerer A, Borodovsky A, Marsico G, Schubert U, Manygoats K, Seifert S, Andree C, Stöter M, Epstein-Barash H, Zhang L, Koteliansky V, Fitzgerald K, Fava E, Bickle M, Kalaidzidis Y, Akinc A, Maier M, Zerial M.

Nat Biotechnol. 2013 Jul;31(7):638-46. doi: 10.1038/nbt.2612. Epub 2013 Jun 23.


Integration of chemical and RNAi multiparametric profiles identifies triggers of intracellular mycobacterial killing.

Sundaramurthy V, Barsacchi R, Samusik N, Marsico G, Gilleron J, Kalaidzidis I, Meyenhofer F, Bickle M, Kalaidzidis Y, Zerial M.

Cell Host Microbe. 2013 Feb 13;13(2):129-42. doi: 10.1016/j.chom.2013.01.008.


Hexavalent chromium at low concentration alters Sertoli cell barrier and connexin 43 gap junction but not claudin-11 and N-cadherin in the rat seminiferous tubule culture model.

Carette D, Perrard MH, Prisant N, Gilleron J, Pointis G, Segretain D, Durand P.

Toxicol Appl Pharmacol. 2013 Apr 1;268(1):27-36. doi: 10.1016/j.taap.2013.01.016. Epub 2013 Jan 26.


The anti-mitotic drug griseofulvin induces apoptosis of human germ cell tumor cells through a connexin 43-dependent molecular mechanism.

Mauro V, Carette D, Pontier-Bres R, Dompierre J, Czerucka D, Segretain D, Gilleron J, Pointis G.

Apoptosis. 2013 Apr;18(4):480-91. doi: 10.1007/s10495-012-0800-8.


[Key role of Rab5: from endosome biogenesis to liver metabolism].

Gilleron J, Zeigerer A, Marsico G, Galvez T, Zerial M.

Med Sci (Paris). 2012 Dec;28(12):1041-4. doi: 10.1051/medsci/20122812007. Epub 2012 Dec 21. French. No abstract available.


SnapShot: Mammalian Rab proteins in endocytic trafficking.

Galvez T, Gilleron J, Zerial M, O'Sullivan GA.

Cell. 2012 Sep 28;151(1):234-234.e2. doi: 10.1016/j.cell.2012.09.013. No abstract available.


Connexin 43 a check-point component of cell proliferation implicated in a wide range of human testis diseases.

Chevallier D, Carette D, Segretain D, Gilleron J, Pointis G.

Cell Mol Life Sci. 2013 Apr;70(7):1207-20. doi: 10.1007/s00018-012-1121-3. Epub 2012 Aug 24. Review.


Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.

Zeigerer A, Gilleron J, Bogorad RL, Marsico G, Nonaka H, Seifert S, Epstein-Barash H, Kuchimanchi S, Peng CG, Ruda VM, Del Conte-Zerial P, Hengstler JG, Kalaidzidis Y, Koteliansky V, Zerial M.

Nature. 2012 May 23;485(7399):465-70. doi: 10.1038/nature11133.


Molecular connexin partner remodeling orchestrates connexin traffic: from physiology to pathophysiology.

Gilleron J, Carette D, Chevallier D, Segretain D, Pointis G.

Crit Rev Biochem Mol Biol. 2012 Sep;47(5):407-23. doi: 10.3109/10409238.2012.683482. Epub 2012 May 3. Review.


Testicular connexin 43, a precocious molecular target for the effect of environmental toxicants on male fertility.

Pointis G, Gilleron J, Carette D, Segretain D.

Spermatogenesis. 2011 Oct;1(4):303-317. Epub 2011 Oct 1.


Chemical connexin impairment in the developing gonad associated with offspring infertility.

Gilleron J, Malassiné A, Carette D, Segretain D, Pointis G.

Curr Med Chem. 2011;18(33):5145-58. Review.


The large GTPase dynamin2: a new player in connexin 43 gap junction endocytosis, recycling and degradation.

Gilleron J, Carette D, Fiorini C, Dompierre J, Macia E, Denizot JP, Segretain D, Pointis G.

Int J Biochem Cell Biol. 2011 Aug;43(8):1208-17. doi: 10.1016/j.biocel.2011.04.014. Epub 2011 Apr 27.


Major involvement of connexin 43 in seminiferous epithelial junction dynamics and male fertility.

Carette D, Weider K, Gilleron J, Giese S, Dompierre J, Bergmann M, Brehm R, Denizot JP, Segretain D, Pointis G.

Dev Biol. 2010 Oct 1;346(1):54-67. doi: 10.1016/j.ydbio.2010.07.014. Epub 2010 Jul 22.


Physiological and physiopathological aspects of connexins and communicating gap junctions in spermatogenesis.

Pointis G, Gilleron J, Carette D, Segretain D.

Philos Trans R Soc Lond B Biol Sci. 2010 May 27;365(1546):1607-20. doi: 10.1098/rstb.2009.0114. Review.


Differential time course of FSH/FSH receptor complex endocytosis within sertoli and germ cells during rat testis development.

Segretain D, Gilleron J, Carette D, Denizot JP, Pointis G.

Dev Dyn. 2010 Apr;239(4):1113-23. doi: 10.1002/dvdy.22261.


Heteromeric connexin 43/connexin 33 complex endocytosis: a connexin phosphorylation independent mechanism.

Carette D, Gilleron J, Segretain D, Pointis G.

Biochimie. 2010 May;92(5):555-9. doi: 10.1016/j.biochi.2010.02.003. Epub 2010 Feb 10.


Nonstructural NSs protein of rift valley fever virus interacts with pericentromeric DNA sequences of the host cell, inducing chromosome cohesion and segregation defects.

Mansuroglu Z, Josse T, Gilleron J, Billecocq A, Leger P, Bouloy M, Bonnefoy E.

J Virol. 2010 Jan;84(2):928-39. doi: 10.1128/JVI.01165-09. Epub 2009 Nov 4.


Contraceptive steroids from pharmaceutical waste perturbate junctional communication in Sertoli cells.

Tramoni M, Gilleron J, Tahiri K, Carette D, Corvol MT, Segretain D, Pointis G, Savouret JF.

Biochimie. 2009 Nov-Dec;91(11-12):1366-75. doi: 10.1016/j.biochi.2009.09.008. Epub 2009 Sep 22.


Connexin 43 gap junction plaque endocytosis implies molecular remodelling of ZO-1 and c-Src partners.

Gilleron J, Carette D, Fiorini C, Benkdane M, Segretain D, Pointis G.

Commun Integr Biol. 2009;2(2):104-6.


Connexin 33 impairs gap junction functionality by accelerating connexin 43 gap junction plaque endocytosis.

Carette D, Gilleron J, Decrouy X, Fiorini C, Diry M, Segretain D, Pointis G.

Traffic. 2009 Sep;10(9):1272-85. doi: 10.1111/j.1600-0854.2009.00949.x. Epub 2009 May 27.


Three-dimensional analysis of connexin 43 gap junction in the ex vivo rat seminiferous tubules: short-term effects of hormonal effectors.

Gilleron J, Carette D, Carpentier F, Segretain D, Pointis G.

Microsc Res Tech. 2009 Nov;72(11):845-55. doi: 10.1002/jemt.20731.


Connexin 43 a potential regulator of cell proliferation and apoptosis within the seminiferous epithelium.

Gilleron J, Carette D, Durand P, Pointis G, Segretain D.

Int J Biochem Cell Biol. 2009 Jun;41(6):1381-90. doi: 10.1016/j.biocel.2008.12.008. Epub 2008 Dec 24.


Molecular reorganization of Cx43, Zo-1 and Src complexes during the endocytosis of gap junction plaques in response to a non-genomic carcinogen.

Gilleron J, Fiorini C, Carette D, Avondet C, Falk MM, Segretain D, Pointis G.

J Cell Sci. 2008 Dec 15;121(Pt 24):4069-78. doi: 10.1242/jcs.033373. Epub 2008 Nov 25.


Cyclosporine triggers endoplasmic reticulum stress in endothelial cells: a role for endothelial phenotypic changes and death.

Bouvier N, Flinois JP, Gilleron J, Sauvage FL, Legendre C, Beaune P, Thervet E, Anglicheau D, Pallet N.

Am J Physiol Renal Physiol. 2009 Jan;296(1):F160-9. doi: 10.1152/ajprenal.90567.2008. Epub 2008 Nov 5.


Autophagy protects renal tubular cells against cyclosporine toxicity.

Pallet N, Bouvier N, Legendre C, Gilleron J, Codogno P, Beaune P, Thervet E, Anglicheau D.

Autophagy. 2008 Aug;4(6):783-91. Epub 2008 Jun 20.


Meiotic progression of rat spermatocytes requires mitogen-activated protein kinases of Sertoli cells and close contacts between the germ cells and the Sertoli cells.

Godet M, Sabido O, Gilleron J, Durand P.

Dev Biol. 2008 Mar 1;315(1):173-88. doi: 10.1016/j.ydbio.2007.12.019. Epub 2008 Jan 29.


Accelerated internalization of junctional membrane proteins (connexin 43, N-cadherin and ZO-1) within endocytic vacuoles: an early event of DDT carcinogenicity.

Fiorini C, Gilleron J, Carette D, Valette A, Tilloy A, Chevalier S, Segretain D, Pointis G.

Biochim Biophys Acta. 2008 Jan;1778(1):56-67. Epub 2007 Sep 14.


Connexins as precocious markers and molecular targets for chemical and pharmacological agents in carcinogenesis.

Pointis G, Fiorini C, Gilleron J, Carette D, Segretain D.

Curr Med Chem. 2007;14(21):2288-303. Review.


A potential novel mechanism involving connexin 43 gap junction for control of sertoli cell proliferation by thyroid hormones.

Gilleron J, Nebout M, Scarabelli L, Senegas-Balas F, Palmero S, Segretain D, Pointis G.

J Cell Physiol. 2006 Oct;209(1):153-61.


[Private duty nursing in oncology].

Gilleron JP.

Soins. 1991 Jul-Aug;(550-551):31-4. French. No abstract available.


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