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Items: 22

1.

A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice.

Gawenis LR, Hodges CA, McHugh DR, Valerio DM, Miron A, Cotton CU, Liu J, Walker NM, Strubberg AM, Gillen AE, Mutolo MJ, Kotzamanis G, Bosch J, Harris A, Drumm ML, Clarke LL.

Sci Rep. 2019 Aug 14;9(1):11828. doi: 10.1038/s41598-019-48105-4.

2.

Chronic Liver Disease in Humans Causes Expansion and Differentiation of Liver Lymphatic Endothelial Cells.

Tamburini BAJ, Finlon JM, Gillen AE, Kriss MS, Riemondy KA, Fu R, Schuyler RP, Hesselberth JR, Rosen HR, Burchill MA.

Front Immunol. 2019 May 15;10:1036. doi: 10.3389/fimmu.2019.01036. eCollection 2019.

3.

Single cell RNA sequencing identifies TGFβ as a key regenerative cue following LPS-induced lung injury.

Riemondy KA, Jansing NL, Jiang P, Redente EF, Gillen AE, Fu R, Miller AJ, Spence JR, Gerber AN, Hesselberth JR, Zemans RL.

JCI Insight. 2019 Mar 26;5. pii: 123637. doi: 10.1172/jci.insight.123637.

4.

Recovery and analysis of transcriptome subsets from pooled single-cell RNA-seq libraries.

Riemondy KA, Ransom M, Alderman C, Gillen AE, Fu R, Finlay-Schultz J, Kirkpatrick GD, Di Paola J, Kabos P, Sartorius CA, Hesselberth JR.

Nucleic Acids Res. 2019 Feb 28;47(4):e20. doi: 10.1093/nar/gky1204.

5.

Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.

Pollyea DA, Stevens BM, Jones CL, Winters A, Pei S, Minhajuddin M, D'Alessandro A, Culp-Hill R, Riemondy KA, Gillen AE, Hesselberth JR, Abbott D, Schatz D, Gutman JA, Purev E, Smith C, Jordan CT.

Nat Med. 2018 Dec;24(12):1859-1866. doi: 10.1038/s41591-018-0233-1. Epub 2018 Nov 12.

PMID:
30420752
6.

Dynamic temperature-sensitive A-to-I RNA editing in the brain of a heterothermic mammal during hibernation.

Riemondy KA, Gillen AE, White EA, Bogren LK, Hesselberth JR, Martin SL.

RNA. 2018 Nov;24(11):1481-1495. doi: 10.1261/rna.066522.118. Epub 2018 Jul 31.

PMID:
30065024
7.

FGFR1 underlies obesity-associated progression of estrogen receptor-positive breast cancer after estrogen deprivation.

Wellberg EA, Kabos P, Gillen AE, Jacobsen BM, Brechbuhl HM, Johnson SJ, Rudolph MC, Edgerton SM, Thor AD, Anderson SM, Elias A, Zhou XK, Iyengar NM, Morrow M, Falcone DJ, El-Hely O, Dannenberg AJ, Sartorius CA, MacLean PS.

JCI Insight. 2018 Jul 26;3(14). pii: 120594. doi: 10.1172/jci.insight.120594. eCollection 2018 Jul 26.

8.

Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells.

Gillen AE, Yang R, Cotton CU, Perez A, Randell SH, Leir SH, Harris A.

J Cyst Fibros. 2018 Jul;17(4):444-453. doi: 10.1016/j.jcf.2018.01.009. Epub 2018 Feb 17.

9.

Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases.

Contreras-Zárate MJ, Ormond DR, Gillen AE, Hanna C, Day NL, Serkova NJ, Jacobsen BM, Edgerton SM, Thor AD, Borges VF, Lillehei KO, Graner MW, Kabos P, Cittelly DM.

Front Oncol. 2017 Nov 2;7:252. doi: 10.3389/fonc.2017.00252. eCollection 2017.

10.

Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes.

Gillen AE, Brechbuhl HM, Yamamoto TM, Kline E, Pillai MM, Hesselberth JR, Kabos P.

Mol Cancer Res. 2017 Dec;15(12):1741-1751. doi: 10.1158/1541-7786.MCR-17-0010. Epub 2017 Sep 14.

11.

Breast Cancer Suppression by Progesterone Receptors Is Mediated by Their Modulation of Estrogen Receptors and RNA Polymerase III.

Finlay-Schultz J, Gillen AE, Brechbuhl HM, Ivie JJ, Matthews SB, Jacobsen BM, Bentley DL, Kabos P, Sartorius CA.

Cancer Res. 2017 Sep 15;77(18):4934-4946. doi: 10.1158/0008-5472.CAN-16-3541. Epub 2017 Jul 20.

12.

Fibroblast Subtypes Regulate Responsiveness of Luminal Breast Cancer to Estrogen.

Brechbuhl HM, Finlay-Schultz J, Yamamoto TM, Gillen AE, Cittelly DM, Tan AC, Sams SB, Pillai MM, Elias AD, Robinson WA, Sartorius CA, Kabos P.

Clin Cancer Res. 2017 Apr 1;23(7):1710-1721. doi: 10.1158/1078-0432.CCR-15-2851. Epub 2016 Oct 4.

13.

Improvements to the HITS-CLIP protocol eliminate widespread mispriming artifacts.

Gillen AE, Yamamoto TM, Kline E, Hesselberth JR, Kabos P.

BMC Genomics. 2016 May 5;17:338. doi: 10.1186/s12864-016-2675-5.

14.

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.

Towers CG, Guarnieri AL, Micalizzi DS, Harrell JC, Gillen AE, Kim J, Wang CA, Oliphant MUJ, Drasin DJ, Guney MA, Kabos P, Sartorius CA, Tan AC, Perou CM, Espinosa JM, Ford HL.

Nat Commun. 2015 Dec 21;6:10077. doi: 10.1038/ncomms10077.

15.

HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.

Pillai MM, Gillen AE, Yamamoto TM, Kline E, Brown J, Flory K, Hesselberth JR, Kabos P.

Breast Cancer Res Treat. 2014 Jul;146(1):85-97. doi: 10.1007/s10549-014-3004-9. Epub 2014 Jun 7.

16.

A genome-wide analysis of open chromatin in human epididymis epithelial cells reveals candidate regulatory elements for genes coordinating epididymal function.

Bischof JM, Gillen AE, Song L, Gosalia N, London D, Furey TS, Crawford GE, Harris A.

Biol Reprod. 2013 Oct 31;89(4):104. doi: 10.1095/biolreprod.113.110403. Print 2013 Oct.

17.

Characterization of a large human transgene following invasin-mediated delivery in a bacterial artificial chromosome.

Gillen AE, Lucas CA, Haussecker PL, Kosak ST, Harris A.

Chromosoma. 2013 Oct;122(5):351-61. doi: 10.1007/s00412-013-0418-9. Epub 2013 Jun 9.

18.

Transcriptional regulation of CFTR gene expression.

Gillen AE, Harris A.

Front Biosci (Elite Ed). 2012 Jan 1;4:587-92. Review.

PMID:
22201896
19.

Nucleosome occupancy reveals regulatory elements of the CFTR promoter.

Ott CJ, Bischof JM, Unti KM, Gillen AE, Leir SH, Harris A.

Nucleic Acids Res. 2012 Jan;40(2):625-37. doi: 10.1093/nar/gkr754. Epub 2011 Sep 24.

20.

The role of CTCF in coordinating the expression of single gene loci.

Gillen AE, Harris A.

Biochem Cell Biol. 2011 Oct;89(5):489-94. doi: 10.1139/o11-040. Epub 2011 Sep 14. Review.

PMID:
21916612
21.

MicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene.

Gillen AE, Gosalia N, Leir SH, Harris A.

Biochem J. 2011 Aug 15;438(1):25-32. doi: 10.1042/BJ20110672.

22.

An insulator element 3' to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells.

Blackledge NP, Ott CJ, Gillen AE, Harris A.

Nucleic Acids Res. 2009 Mar;37(4):1086-94. doi: 10.1093/nar/gkn1056. Epub 2009 Jan 7.

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