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Items: 1 to 50 of 65

1.

Sunitinib Prior to Planned Nephrectomy in Metastatic Renal Cell Carcinoma: Angiogenesis Biomarkers Predict Clinical Outcome in the Prospective Phase II PREINSUT Trial.

Mauge L, Mejean A, Fournier L, Pereira H, Etienne-Grimaldi MC, Levionnois E, Caty A, Abadie-Lacourtoisie S, Culine S, Le Moulec S, Linassier C, Théodore C, Ravaud A, Albiges L, Grine A, Tartour E, Milano G, Gille AS, Verkarre V, Helley D, Oudard S; PREINSUT study group.

Clin Cancer Res. 2018 Jul 30. doi: 10.1158/1078-0432.CCR-18-1045. [Epub ahead of print]

PMID:
30061359
2.

Bioavailability and Safety of Nutrients from the Microalgae Chlorella vulgaris, Nannochloropsis oceanica and Phaeodactylum tricornutum in C57BL/6 Mice.

Neumann U, Derwenskus F, Gille A, Louis S, Schmid-Staiger U, Briviba K, Bischoff SC.

Nutrients. 2018 Jul 26;10(8). pii: E965. doi: 10.3390/nu10080965.

3.

CSL112 (Apolipoprotein A-I [Human]) Enhances Cholesterol Efflux Similarly in Healthy Individuals and Stable Atherosclerotic Disease Patients.

Gille A, D'Andrea D, Tortorici MA, Hartel G, Wright SD.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):953-963. doi: 10.1161/ATVBAHA.118.310538. Epub 2018 Feb 8.

4.

High beat-to-beat blood pressure variability in atrial fibrillation compared to sinus rhythm.

Olbers J, Gille A, Ljungman P, Rosenqvist M, Östergren J, Witt N.

Blood Press. 2018 Oct;27(5):249-255. doi: 10.1080/08037051.2018.1436400. Epub 2018 Feb 7.

PMID:
29415571
5.

Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1.

Morland C, Andersson KA, Haugen ØP, Hadzic A, Kleppa L, Gille A, Rinholm JE, Palibrk V, Diget EH, Kennedy LH, Stølen T, Hennestad E, Moldestad O, Cai Y, Puchades M, Offermanns S, Vervaeke K, Bjørås M, Wisløff U, Storm-Mathisen J, Bergersen LH.

Nat Commun. 2017 May 23;8:15557. doi: 10.1038/ncomms15557.

6.

Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112: Effects on Cholesterol Efflux, Anti-Inflammatory and Antioxidative Activity.

Didichenko SA, Navdaev AV, Cukier AM, Gille A, Schuetz P, Spycher MO, Thérond P, Chapman MJ, Kontush A, Wright SD.

Circ Res. 2016 Sep 2;119(6):751-63. doi: 10.1161/CIRCRESAHA.116.308685. Epub 2016 Jul 19.

7.

Bioaccessibility of carotenoids from Chlorella vulgaris and Chlamydomonas reinhardtii.

Gille A, Trautmann A, Posten C, Briviba K.

Int J Food Sci Nutr. 2015 Aug;67(5):507-13. doi: 10.1080/09637486.2016.1181158. Epub 2016 May 5.

PMID:
27146695
8.

Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component.

Herzog E, Pragst I, Waelchli M, Gille A, Schenk S, Mueller-Cohrs J, Diditchenko S, Zanoni P, Cuchel M, Seubert A, Rader DJ, Wright SD.

J Appl Toxicol. 2016 Aug;36(8):1038-47. doi: 10.1002/jat.3264. Epub 2015 Dec 9.

PMID:
26651060
9.

Rural-Urban Differences in Chronic Disease and Drug Utilization in Older Oregonians.

Goeres LM, Gille A, Furuno JP, Erten-Lyons D, Hartung DM, Calvert JF, Ahmed SM, Lee DS.

J Rural Health. 2016 Jun;32(3):269-79. doi: 10.1111/jrh.12153. Epub 2015 Oct 30.

10.

Modulation of cellular thiol status affects FoxO activity and life span.

Urban N, Tsitsipatis D, Gille A, Hamann I, Hou X, Klotz LO.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S53. doi: 10.1016/j.freeradbiomed.2014.10.826. Epub 2014 Dec 10.

PMID:
26461409
11.

Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial.

Tricoci P, D'Andrea DM, Gurbel PA, Yao Z, Cuchel M, Winston B, Schott R, Weiss R, Blazing MA, Cannon L, Bailey A, Angiolillo DJ, Gille A, Shear CL, Wright SD, Alexander JH.

J Am Heart Assoc. 2015 Aug 25;4(8):e002171. doi: 10.1161/JAHA.115.002171.

12.

Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.

Nøhr MK, Egerod KL, Christiansen SH, Gille A, Offermanns S, Schwartz TW, Møller M.

Neuroscience. 2015 Apr 2;290:126-37. doi: 10.1016/j.neuroscience.2015.01.040. Epub 2015 Jan 28.

PMID:
25637492
13.

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.

Tang C, Ahmed K, Gille A, Lu S, Gröne HJ, Tunaru S, Offermanns S.

Nat Med. 2015 Feb;21(2):173-7. doi: 10.1038/nm.3779. Epub 2015 Jan 12.

PMID:
25581519
14.
15.

CSL112 enhances biomarkers of reverse cholesterol transport after single and multiple infusions in healthy subjects.

Gille A, Easton R, D'Andrea D, Wright SD, Shear CL.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2106-14. doi: 10.1161/ATVBAHA.114.303720. Epub 2014 Jun 26.

PMID:
24969776
16.

Alignment-Annotator web server: rendering and annotating sequence alignments.

Gille C, Fähling M, Weyand B, Wieland T, Gille A.

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W3-6. doi: 10.1093/nar/gku400. Epub 2014 May 9.

17.

Sequence alignment visualization in HTML5 without Java.

Gille C, Birgit W, Gille A.

Bioinformatics. 2014 Jan 1;30(1):121-2. doi: 10.1093/bioinformatics/btt614. Epub 2013 Nov 21.

PMID:
24273246
18.

A multiple ascending dose study of CSL112, an infused formulation of ApoA-I.

Easton R, Gille A, D'Andrea D, Davis R, Wright SD, Shear C.

J Clin Pharmacol. 2014 Mar;54(3):301-10. doi: 10.1002/jcph.194. Epub 2013 Oct 22.

PMID:
24122814
19.

A Case of Mild Hypertension what can we Learn from over 900 Days of Data Records?

Gille K, Heinze C, Gille A, Trutschel U.

Biomed Tech (Berl). 2013 Sep 7. pii: /j/bmte.2013.58.issue-s1-I/bmt-2013-4226/bmt-2013-4226.xml. doi: 10.1515/bmt-2013-4226. [Epub ahead of print] No abstract available.

PMID:
24042876
20.

GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes.

Nøhr MK, Pedersen MH, Gille A, Egerod KL, Engelstoft MS, Husted AS, Sichlau RM, Grunddal KV, Poulsen SS, Han S, Jones RM, Offermanns S, Schwartz TW.

Endocrinology. 2013 Oct;154(10):3552-64. doi: 10.1210/en.2013-1142. Epub 2013 Jul 24.

PMID:
23885020
21.

Novel formulation of a reconstituted high-density lipoprotein (CSL112) dramatically enhances ABCA1-dependent cholesterol efflux.

Diditchenko S, Gille A, Pragst I, Stadler D, Waelchli M, Hamilton R, Leis A, Wright SD.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2202-11. doi: 10.1161/ATVBAHA.113.301981. Epub 2013 Jul 18.

PMID:
23868939
22.

Role of HCA₂ (GPR109A) in nicotinic acid and fumaric acid ester-induced effects on the skin.

Hanson J, Gille A, Offermanns S.

Pharmacol Ther. 2012 Oct;136(1):1-7. doi: 10.1016/j.pharmthera.2012.06.003. Epub 2012 Jun 26. Review.

PMID:
22743741
23.

Inhibitors of membranous adenylyl cyclases.

Seifert R, Lushington GH, Mou TC, Gille A, Sprang SR.

Trends Pharmacol Sci. 2012 Feb;33(2):64-78. doi: 10.1016/j.tips.2011.10.006. Epub 2011 Nov 17. Review.

24.

Structure-activity relationships for the interactions of 2'- and 3'-(O)-(N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases.

Pinto C, Lushington GH, Richter M, Gille A, Geduhn J, König B, Mou TC, Sprang SR, Seifert R.

Biochem Pharmacol. 2011 Aug 15;82(4):358-70. doi: 10.1016/j.bcp.2011.05.010. Epub 2011 May 18.

25.

Structural basis for the high-affinity inhibition of mammalian membranous adenylyl cyclase by 2',3'-o-(N-methylanthraniloyl)-inosine 5'-triphosphate.

Hübner M, Dixit A, Mou TC, Lushington GH, Pinto C, Gille A, Geduhn J, König B, Sprang SR, Seifert R.

Mol Pharmacol. 2011 Jul;80(1):87-96. doi: 10.1124/mol.111.071894. Epub 2011 Apr 15.

26.

Gosteli-Claisen rearrangement of propargyl vinyl ethers: cascading molecular rearrangements.

Gille A, Rehbein J, Hiersemann M.

Org Lett. 2011 Apr 15;13(8):2122-5. doi: 10.1021/ol200558j. Epub 2011 Mar 23.

PMID:
21428300
27.

Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells.

Lukasova M, Malaval C, Gille A, Kero J, Offermanns S.

J Clin Invest. 2011 Mar;121(3):1163-73. doi: 10.1172/JCI41651. Epub 2011 Feb 7.

28.

(-)-Lytophilippine A: synthesis of a C1-C18 building block.

Gille A, Hiersemann M.

Org Lett. 2010 Nov 19;12(22):5258-61. doi: 10.1021/ol1023008. Epub 2010 Oct 25.

PMID:
20973508
29.

Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice.

Hanson J, Gille A, Zwykiel S, Lukasova M, Clausen BE, Ahmed K, Tunaru S, Wirth A, Offermanns S.

J Clin Invest. 2010 Aug;120(8):2910-9. doi: 10.1172/JCI42273. Epub 2010 Jul 26.

30.

Frustrated Lewis pairs derived from N-heterocyclic carbenes and Lewis acids.

Chase PA, Gille AL, Gilbert TM, Stephan DW.

Dalton Trans. 2009 Sep 21;(35):7179-88. doi: 10.1039/b908737k. Epub 2009 Jul 23.

PMID:
20449161
31.

An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81.

Ahmed K, Tunaru S, Tang C, Müller M, Gille A, Sassmann A, Hanson J, Offermanns S.

Cell Metab. 2010 Apr 7;11(4):311-9. doi: 10.1016/j.cmet.2010.02.012.

32.

From classical adducts to frustrated Lewis pairs: steric effects in the interactions of pyridines and B(C6F5)3.

Geier SJ, Gille AL, Gilbert TM, Stephan DW.

Inorg Chem. 2009 Nov 2;48(21):10466-74. doi: 10.1021/ic901726b.

PMID:
19810714
33.

Differential inhibition of various adenylyl cyclase isoforms and soluble guanylyl cyclase by 2',3'-O-(2,4,6-trinitrophenyl)-substituted nucleoside 5'-triphosphates.

Suryanarayana S, Göttle M, Hübner M, Gille A, Mou TC, Sprang SR, Richter M, Seifert R.

J Pharmacol Exp Ther. 2009 Sep;330(3):687-95. doi: 10.1124/jpet.109.155432. Epub 2009 Jun 3.

34.

Differential interactions of the catalytic subunits of adenylyl cyclase with forskolin analogs.

Pinto C, Hübner M, Gille A, Richter M, Mou TC, Sprang SR, Seifert R.

Biochem Pharmacol. 2009 Jul 1;78(1):62-9. doi: 10.1016/j.bcp.2009.03.023. Epub 2009 Apr 2.

35.

LASIK for myopia using the Zeiss VisuMax femtosecond laser and MEL 80 excimer laser.

Blum M, Kunert K, Gille A, Sekundo W.

J Refract Surg. 2009 Apr;25(4):350-6.

PMID:
19431925
36.

Characterization of mouse heart adenylyl cyclase.

Göttle M, Geduhn J, König B, Gille A, Höcherl K, Seifert R.

J Pharmacol Exp Ther. 2009 Jun;329(3):1156-65. doi: 10.1124/jpet.109.150953. Epub 2009 Mar 23.

37.

(±)-syn-Isopropyl 4-(1,1,1,3,3,3-hexa-fluoro-propan-2-yl-oxy)-1-hydr-oxy-3-methyl-2-(prop-1-yn-yl)cyclo-pent-2-ene-carboxyl-ate.

Gille A, Schürmann M, Preut H, Hiersemann M.

Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 20;65(Pt 7):o1660. doi: 10.1107/S1600536809023162.

38.

(3R,4R,5S)-4-Hydr-oxy-3-methyl-5-[(2S,3R)-3-methyl-pent-4-en-2-yl]-4,5-dihydro-furan-2(3H)-one.

Gille A, Schürmann M, Preut H, Hiersemann M.

Acta Crystallogr Sect E Struct Rep Online. 2009 Nov 28;65(Pt 12):o3274. doi: 10.1107/S1600536809050399.

39.

Molecular analysis of the interaction of anthrax adenylyl cyclase toxin, edema factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-substituted purine and pyrimidine nucleotides.

Taha HM, Schmidt J, Göttle M, Suryanarayana S, Shen Y, Tang WJ, Gille A, Geduhn J, König B, Dove S, Seifert R.

Mol Pharmacol. 2009 Mar;75(3):693-703. doi: 10.1124/mol.108.052340. Epub 2008 Dec 4.

41.

First efficacy and safety study of femtosecond lenticule extraction for the correction of myopia: six-month results.

Sekundo W, Kunert K, Russmann C, Gille A, Bissmann W, Stobrawa G, Sticker M, Bischoff M, Blum M.

J Cataract Refract Surg. 2008 Sep;34(9):1513-20. doi: 10.1016/j.jcrs.2008.05.033. Erratum in: J Cataract Refract Surg. 2008 Nov;34(11):1819.

PMID:
18721712
42.

Ca2+ signalling of kinins in cells expressing rat, mouse and human B1/B2-receptor.

Zubakova R, Gille A, Faussner A, Hilgenfeldt U.

Int Immunopharmacol. 2008 Feb;8(2):276-81. doi: 10.1016/j.intimp.2007.10.001. Epub 2007 Oct 25.

PMID:
18182240
43.

(3S,4S,5R)-4-Hydr-oxy-3-methyl-5-[(2S,3R)-3-methyl-pent-4-en-2-yl]-4,5-dihydro-furan-2(3H)-one.

Gille A, Bläser D, Boese R, Preut H, Hiersemann M.

Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 17;65(Pt 1):o154. doi: 10.1107/S1600536808042414.

44.

(3S,4S,5S)-4-Hydr-oxy-3-methyl-5-[(2S,3R)-3-methyl-pent-4-en-2-yl]-4,5-dihydro-furan-2(3H)-one.

Gille A, Schürmann M, Preut H, Hiersemann M.

Acta Crystallogr Sect E Struct Rep Online. 2008 Aug 30;64(Pt 9):o1835. doi: 10.1107/S1600536808026998.

45.

Nicotinic acid: pharmacological effects and mechanisms of action.

Gille A, Bodor ET, Ahmed K, Offermanns S.

Annu Rev Pharmacol Toxicol. 2008;48:79-106. Review.

PMID:
17705685
46.

Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells.

Benyó Z, Gille A, Bennett CL, Clausen BE, Offermanns S.

Mol Pharmacol. 2006 Dec;70(6):1844-9. Epub 2006 Sep 28.

47.

Broad specificity of mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors.

Mou TC, Gille A, Suryanarayana S, Richter M, Seifert R, Sprang SR.

Mol Pharmacol. 2006 Sep;70(3):878-86. Epub 2006 Jun 9.

48.

GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.

Benyó Z, Gille A, Kero J, Csiky M, Suchánková MC, Nüsing RM, Moers A, Pfeffer K, Offermanns S.

J Clin Invest. 2005 Dec;115(12):3634-40.

49.

Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.

Gille A, Guo J, Mou TC, Doughty MB, Lushington GH, Seifert R.

Biochem Pharmacol. 2005 Dec 19;71(1-2):89-97. Epub 2005 Nov 4.

PMID:
16271707
50.

Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate.

Mou TC, Gille A, Fancy DA, Seifert R, Sprang SR.

J Biol Chem. 2005 Feb 25;280(8):7253-61. Epub 2004 Dec 9.

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