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Revisiting the clinical and biologic relevance of partial PTEN loss in melanoma.

Giles KM, Rosenbaum BE, Berger M, Izsak A, Li Y, Illa Bochaca I, Vega-Saenz de Miera E, Wang J, Darvishian F, Zhong H, Osman I.

J Invest Dermatol. 2018 Aug 24. pii: S0022-202X(18)32503-X. doi: 10.1016/j.jid.2018.07.031. [Epub ahead of print]


Evaluation of cross-platform and interlaboratory concordance via consensus modelling of genomic measurements.

Peters TJ, French HJ, Bradford ST, Pidsley R, Stirzaker C, Varinli H, Nair S, Qu W, Song J, Giles KA, Statham AL, Speirs H, Speed TP, Clark SJ.

Bioinformatics. 2018 Aug 1. doi: 10.1093/bioinformatics/bty675. [Epub ahead of print]


Financial implications of coding inaccuracies in patients undergoing elective endovascular abdominal aortic aneurysm repair.

Ayub S, Scali ST, Richter J, Huber TS, Beck AW, Fatima J, Berceli SA, Upchurch GR, Arnaoutakis D, Back MR, Giles KA.

J Vasc Surg. 2018 Jun 21. pii: S0741-5214(18)30982-0. doi: 10.1016/j.jvs.2018.04.027. [Epub ahead of print]


Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer.

Yang Z, Shah K, Busby T, Giles K, Khodadadi-Jamayran A, Li W, Jiang H.

J Clin Invest. 2018 Aug 1;128(8):3605-3618. doi: 10.1172/JCI97072. Epub 2018 Jul 23.


Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation.

Knight JM, Kerswill SA, Hari P, Cole SW, Logan BR, D'Souza A, Shah NN, Horowitz MM, Stolley MR, Sloan EK, Giles KE, Costanzo ES, Hamadani M, Chhabra S, Dhakal B, Rizzo JD.

BMC Cancer. 2018 May 24;18(1):593. doi: 10.1186/s12885-018-4509-0.


Identifying key membrane protein lipid interactions using mass spectrometry.

Gupta K, Li J, Liko I, Gault J, Bechara C, Wu D, Hopper JTS, Giles K, Benesch JLP, Robinson CV.

Nat Protoc. 2018 May;13(5):1106-1120. doi: 10.1038/nprot.2018.014. Epub 2018 Apr 26.


The Weekend Effect in AAA Repair.

O'Donnell TFX, Li C, Swerdlow NJ, Liang P, Pothof AB, Patel VI, Giles KA, Malas MB, Schermerhorn ML.

Ann Surg. 2018 Apr 18. doi: 10.1097/SLA.0000000000002773. [Epub ahead of print]


Landscape Context Affects Aphid Parasitism by Lysiphlebus testaceipes (Hymenoptera: Aphidiinae) in Wheat Fields.

Elliott NC, Brewer MJ, Giles KL.

Environ Entomol. 2018 Aug 11;47(4):803-811. doi: 10.1093/ee/nvy035.


Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors.

Gowen MF, Giles KM, Simpson D, Tchack J, Zhou H, Moran U, Dawood Z, Pavlick AC, Hu S, Wilson MA, Zhong H, Krogsgaard M, Kirchhoff T, Osman I.

J Transl Med. 2018 Apr 2;16(1):82. doi: 10.1186/s12967-018-1452-4.


Outcomes of Thoracic Endovascular Aortic Repair for Acute Type B Dissection in Patients With Intractable Pain or Refractory Hypertension.

Laquian L, Scali ST, Beaver TM, Kubilis P, Beck AW, Giles K, Huber TS, Feezor RJ.

J Endovasc Ther. 2018 Apr;25(2):220-229. doi: 10.1177/1526602818759339.


Postoperative Complications Associated with External Skeletal Fixators in Dogs.

Beever LJ, Giles K, Meeson RL.

Vet Comp Orthop Traumatol. 2018 Feb;31(2):137-143. doi: 10.1055/s-0038-1627477. Epub 2018 Mar 13. Review.


Regional variation in racial disparities among patients with peripheral artery disease.

O'Donnell TFX, Powell C, Deery SE, Darling JD, Hughes K, Giles KA, Wang GJ, Schermerhorn ML.

J Vasc Surg. 2018 Aug;68(2):519-526. doi: 10.1016/j.jvs.2017.10.090. Epub 2018 Feb 16.


Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease.

Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, Giles K, DeGrado WF, Prusiner SB.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E782-E791. doi: 10.1073/pnas.1714966115. Epub 2018 Jan 8.


Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.

Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E11029-E11036. doi: 10.1073/pnas.1717193114. Epub 2017 Dec 4.


A novel vector for transgenesis in the rat CNS.

Lopez TP, Giles K, Dugger BN, Oehler A, Condello C, Krejciova Z, Castaneda JA, Carlson GA, Prusiner SB.

Acta Neuropathol Commun. 2017 Nov 21;5(1):84. doi: 10.1186/s40478-017-0484-y.


Locus of control, optimism, and recollections of depression and self-reported cognitive functioning following treatment for colorectal cancer.

Wilson C, Giles K, Nettelbeck T, Hutchinson A.

Psychooncology. 2018 Feb;27(2):676-682. doi: 10.1002/pon.4567. Epub 2017 Nov 7.


Implementation of a bundled protocol significantly reduces risk of spinal cord ischemia after branched or fenestrated endovascular aortic repair.

Scali ST, Kim M, Kubilis P, Feezor RJ, Giles KA, Miller B, Fatima J, Huber TS, Berceli SA, Back M, Beck AW.

J Vasc Surg. 2018 Feb;67(2):409-423.e4. doi: 10.1016/j.jvs.2017.05.136. Epub 2017 Oct 7.


Outcomes of thoracic endovascular aortic repair in adult coarctation patients.

Lala S, Scali ST, Feezor RJ, Chandrekashar S, Giles KA, Fatima J, Berceli SA, Back MR, Huber TS, Beaver TM, Beck AW.

J Vasc Surg. 2018 Feb;67(2):369-381.e2. doi: 10.1016/j.jvs.2017.06.103. Epub 2017 Sep 22.


miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression.

Epis MR, Giles KM, Beveridge DJ, Richardson KL, Candy PA, Stuart LM, Bentel J, Cohen RJ, Leedman PJ.

Oncotarget. 2017 Jun 27;8(33):55116-55134. doi: 10.18632/oncotarget.18664. eCollection 2017 Aug 15.


Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing.

Zhang Z, Jones AE, Wu W, Kim J, Kang Y, Bi X, Gu Y, Popov IK, Renfrow MB, Vassylyeva MN, Vassylyev DG, Giles KE, Chen D, Kumar A, Fan Y, Tong Y, Liu CF, An W, Chang C, Luo J, Chow LT, Wang H.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7949-E7958. doi: 10.1073/pnas.1711158114. Epub 2017 Aug 30.


Fish oil mitigates myosteatosis and improves chemotherapy efficacy in a preclinical model of colon cancer.

Almasud AA, Giles KH, Miklavcic JJ, Martins KJB, Baracos VE, Putman CT, Guan LL, Mazurak VC.

PLoS One. 2017 Aug 23;12(8):e0183576. doi: 10.1371/journal.pone.0183576. eCollection 2017.


Conjunctival Flora of Human Immunodeficiency Virus Patients on Antiretroviral Treatment.

Giles K, Bilong Y, Dohvoma AV, Ebana SR, Gonsu H.

Ophthalmol Eye Dis. 2017 Aug 3;9:1179172117724760. doi: 10.1177/1179172117724760. eCollection 2017.


Multiple Gas-Phase Conformations of a Synthetic Linear Poly(acrylamide) Polymer Observed Using Ion Mobility-Mass Spectrometry.

Haler JRN, Far J, Aqil A, Claereboudt J, Tomczyk N, Giles K, Jérôme C, De Pauw E.

J Am Soc Mass Spectrom. 2017 Nov;28(11):2492-2499. doi: 10.1007/s13361-017-1769-x. Epub 2017 Aug 14.


Incorporating biological control into IPM decision making.

Giles KL, McCornack BP, Royer TA, Elliott NC.

Curr Opin Insect Sci. 2017 Apr;20:84-89. doi: 10.1016/j.cois.2017.03.009. Epub 2017 May 11. Review.


Mixed methods study on the use of and attitudes towards safety checklists in interventional radiology.

Munn Z, Giles K, Aromataris E, Deakin A, Schultz T, Mandel C, Peters MD, Maddern G, Pearson A, Runciman W.

J Med Imaging Radiat Oncol. 2018 Feb;62(1):32-38. doi: 10.1111/1754-9485.12633. Epub 2017 Jun 10.


Postoperative complications associated with external skeletal fixators in cats.

Beever L, Giles K, Meeson R.

J Feline Med Surg. 2017 Jul;19(7):727-736. doi: 10.1177/1098612X17699466.


Ozone-induced dissociation on a traveling wave high-resolution mass spectrometer for determination of double-bond position in lipids.

Vu N, Brown J, Giles K, Zhang Q.

Rapid Commun Mass Spectrom. 2017 Sep 15;31(17):1415-1423. doi: 10.1002/rcm.7920.


Simultaneous Bilateral Cataract Surgery in Outreach Surgical Camps.

Giles K, Robert ES, Come EM, Wiedemann P.

Ophthalmol Eye Dis. 2017 Apr 20;9:1179172117701738. doi: 10.1177/1179172117701738. eCollection 2017.


Application of Pheromone Traps for Managing Hessian Fly (Diptera: Cecidomyiidae) in the Southern Great Plains.

Knutson AE, Giles KL, Royer TA, Elliott NC, Bradford N.

J Econ Entomol. 2017 Jun 1;110(3):1052-1061. doi: 10.1093/jee/tox088.


Female sex independently predicts mortality after thoracic endovascular aortic repair for intact descending thoracic aortic aneurysms.

Deery SE, Shean KE, Wang GJ, Black JH 3rd, Upchurch GR Jr, Giles KA, Patel VI, Schermerhorn ML; Society for Vascular Surgery Vascular Quality Initiative.

J Vasc Surg. 2017 Jul;66(1):2-8. doi: 10.1016/j.jvs.2016.12.103. Epub 2017 Mar 1.


Bioassays and Inactivation of Prions.

Giles K, Woerman AL, Berry DB, Prusiner SB.

Cold Spring Harb Perspect Biol. 2017 Aug 1;9(8). pii: a023499. doi: 10.1101/cshperspect.a023499. Review.


Outcomes of thoracic endovascular aortic repair using aortic arch chimney stents in high-risk patients.

Voskresensky I, Scali ST, Feezor RJ, Fatima J, Giles KA, Tricarico R, Berceli SA, Beck AW.

J Vasc Surg. 2017 Jul;66(1):9-20.e3. doi: 10.1016/j.jvs.2016.11.063.


α-Synuclein: Multiple System Atrophy Prions.

Woerman AL, Watts JC, Aoyagi A, Giles K, Middleton LT, Prusiner SB.

Cold Spring Harb Perspect Med. 2018 Jul 2;8(7). pii: a024588. doi: 10.1101/cshperspect.a024588. Review.


Developing Therapeutics for PrP Prion Diseases.

Giles K, Olson SH, Prusiner SB.

Cold Spring Harb Perspect Med. 2017 Apr 3;7(4). pii: a023747. doi: 10.1101/cshperspect.a023747. Review.


Structure of a glycoside hydrolase family 50 enzyme from a subfamily that is enriched in human gut microbiome bacteroidetes.

Giles K, Pluvinage B, Boraston AB.

Proteins. 2017 Jan;85(1):182-187. doi: 10.1002/prot.25189. Epub 2016 Nov 4.


Orbital exenteration in immunodeficiency virus-infected patients.

Giles K, Bilong Y, Arlette N, Chantal N, Lucienne BA.

Clin Ophthalmol. 2016 Oct 20;10:2055-2059. eCollection 2016.


Uveal coloboma: about 3 cases at the University Teaching Hospital, Yaounde, Cameroon.

Giles K, Raoul C, Yannick B, Peter W.

Pan Afr Med J. 2016 Jul 8;24:201. eCollection 2016.


Cataract surgery with intraocular lens implantation in children aged 5-15 in local anaesthesia: visual outcomes and complications.

Giles K, Christelle D, Yannick B, Fricke OH, Wiedemann P.

Pan Afr Med J. 2016 Jul 7;24:200. eCollection 2016.


Outcomes after endovascular aneurysm repair conversion and primary aortic repair for urgent and emergency indications in the Society for Vascular Surgery Vascular Quality Initiative.

Scali ST, Runge SJ, Feezor RJ, Giles KA, Fatima J, Berceli SA, Huber TS, Beck AW.

J Vasc Surg. 2016 Aug;64(2):338-347. doi: 10.1016/j.jvs.2016.02.028. Epub 2016 Jun 7.


New High Resolution Ion Mobility Mass Spectrometer Capable of Measurements of Collision Cross Sections from 150 to 520 K.

Ujma J, Giles K, Morris M, Barran PE.

Anal Chem. 2016 Oct 4;88(19):9469-9478. Epub 2016 Sep 15.


Diet composition as a source of variation in experimental animal models of cancer cachexia.

Giles K, Guan C, Jagoe TR, Mazurak V.

J Cachexia Sarcopenia Muscle. 2016 May;7(2):110-25. doi: 10.1002/jcsm.12058. Epub 2015 Oct 15. Review.


Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.

Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB.

J Virol. 2016 Oct 14;90(21):9558-9569. Print 2016 Nov 1.


Towards authentic transgenic mouse models of heritable PrP prion diseases.

Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB.

Acta Neuropathol. 2016 Oct;132(4):593-610. doi: 10.1007/s00401-016-1585-6. Epub 2016 Jun 28.


Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.

Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB.

J Pharmacol Exp Ther. 2016 Sep;358(3):537-47. doi: 10.1124/jpet.116.235556. Epub 2016 Jun 17.


The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells.

Woolnough JL, Atwood BL, Liu Z, Zhao R, Giles KE.

PLoS One. 2016 Jun 14;11(6):e0157276. doi: 10.1371/journal.pone.0157276. eCollection 2016.


Human Argonaute 2 Is Tethered to Ribosomal RNA through MicroRNA Interactions.

Atwood BL, Woolnough JL, Lefevre GM, Saint Just Ribeiro M, Felsenfeld G, Giles KE.

J Biol Chem. 2016 Aug 19;291(34):17919-28. doi: 10.1074/jbc.M116.725051. Epub 2016 Jun 10.


Combining density functional theory (DFT) and collision cross-section (CCS) calculations to analyze the gas-phase behaviour of small molecules and their protonation site isomers.

Boschmans J, Jacobs S, Williams JP, Palmer M, Richardson K, Giles K, Lapthorn C, Herrebout WA, Lemière F, Sobott F.

Analyst. 2016 Jun 20;141(13):4044-54. doi: 10.1039/c5an02456k.


Use of surgical safety checklists in Australian operating theatres: an observational study.

Giles K, Munn Z, Aromataris E, Deakin A, Schultz T, Mandel C, Maddern G, Pearson A, Runciman W.

ANZ J Surg. 2017 Dec;87(12):971-975. doi: 10.1111/ans.13638. Epub 2016 May 25.


microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB.

Giles KM, Brown RA, Ganda C, Podgorny MJ, Candy PA, Wintle LC, Richardson KL, Kalinowski FC, Stuart LM, Epis MR, Haass NK, Herlyn M, Leedman PJ.

Oncotarget. 2016 May 31;7(22):31663-80. doi: 10.18632/oncotarget.9421.


Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations.

Taberlay PC, Achinger-Kawecka J, Lun AT, Buske FA, Sabir K, Gould CM, Zotenko E, Bert SA, Giles KA, Bauer DC, Smyth GK, Stirzaker C, O'Donoghue SI, Clark SJ.

Genome Res. 2016 Jun;26(6):719-31. doi: 10.1101/gr.201517.115. Epub 2016 Apr 6.

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