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Items: 1 to 50 of 161

1.

Damage accrual and mortality over long-term follow-up in 300 patients with systemic lupus erythematosus in a multi-ethnic British cohort.

Segura BT, Bernstein BS, McDonnell T, Wincup C, M Ripoll V, Giles I, Isenberg D, Rahman A.

Rheumatology (Oxford). 2019 Oct 19. pii: kez516. doi: 10.1093/rheumatology/kez516. [Epub ahead of print] No abstract available.

PMID:
31630173
2.

The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS.

McDonnell T, Wincup C, Buchholz I, Pericleous C, Giles I, Ripoll V, Cohen H, Delcea M, Rahman A.

Blood Rev. 2019 Aug 16:100610. doi: 10.1016/j.blre.2019.100610. [Epub ahead of print] Review.

3.

Damage accrual and mortality over long-term follow-up in 300 patients with systemic lupus erythematosus in a multi-ethnic British cohort.

Segura BT, Bernstein BS, McDonnell T, Wincup C, Ripoll V, Giles I, Isenberg D, Rahman A.

Rheumatology (Oxford). 2019 Aug 3. pii: kez292. doi: 10.1093/rheumatology/kez292. [Epub ahead of print]

PMID:
31377781
4.

Antiphospholipid antibody levels in early systemic lupus erythematosus: are they associated with subsequent mortality and vascular events?

Pericleous C, D'Souza A, McDonnell T, Ripoll VM, Leach O, Isenberg D, Giles I, Rahman A.

Rheumatology (Oxford). 2020 Jan 1;59(1):146-152. doi: 10.1093/rheumatology/kez239.

5.

Stratifying management of rheumatic disease for pregnancy and breastfeeding.

Giles I, Yee CS, Gordon C.

Nat Rev Rheumatol. 2019 Jul;15(7):391-402. doi: 10.1038/s41584-019-0240-8. Epub 2019 Jun 11. Review.

PMID:
31186540
6.

Pain and depression are associated with both physical and mental fatigue independently of comorbidities and medications in primary Sjögren's syndrome.

Hackett KL, Davies K, Tarn J, Bragg R, Hargreaves B, Miyamoto S, McMeekin P, Mitchell S, Bowman S, Price EJ, Pease C, Emery P, Andrews J, Lanyon P, Hunter J, Gupta M, Bombardieri M, Sutcliffe N, Pitzalis C, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Vadivelu S, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Griffiths B, Lendrem DW, Ng WF.

RMD Open. 2019 Apr 24;5(1):e000885. doi: 10.1136/rmdopen-2018-000885. eCollection 2019.

7.

Domain I of β2GPI is capable of blocking serum IgA antiphospholipid antibodies binding in vitro: an effect enhanced by PEGylation.

Albay A, Artim-Esen B, Pericleous C, Wincup C, Giles I, Rahman A, McDonnell T.

Lupus. 2019 Jun;28(7):893-897. doi: 10.1177/0961203319851571. Epub 2019 May 24.

8.

Real benefits of ultrasound evaluation of hand and foot synovitis for better characterisation of the disease activity in rheumatoid arthritis.

Ciurtin C, Jones A, Brown G, Sin FE, Raine C, Manson J, Giles I.

Eur Radiol. 2019 Nov;29(11):6345-6354. doi: 10.1007/s00330-019-06187-8. Epub 2019 Apr 26.

9.

Autoimmune rheumatic disease IgG has differential effects upon neutrophil integrin activation that is modulated by the endothelium.

Khawaja AA, Pericleous C, Ripoll VM, Porter JC, Giles IP.

Sci Rep. 2019 Feb 4;9(1):1283. doi: 10.1038/s41598-018-37852-5.

10.

Performance enhancement of free-space optical communications under atmospheric turbulence using modes diversity coherent receipt.

Zheng D, Li Y, Zhou H, Bian Y, Yang C, Li W, Qiu J, Guo H, Hong X, Zuo Y, Giles IP, Tong W, Wu J.

Opt Express. 2018 Oct 29;26(22):28879-28890. doi: 10.1364/OE.26.028879.

PMID:
30470058
11.

PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome.

McDonnell TCR, Willis R, Pericleous C, Ripoll VM, Giles IP, Isenberg DA, Brasier AR, Gonzalez EB, Papalardo E, Romay-Penabad Z, Jamaluddin M, Ioannou Y, Rahman A.

Front Immunol. 2018 Oct 22;9:2413. doi: 10.3389/fimmu.2018.02413. eCollection 2018.

12.

Does Rheumatoid Arthritis Really Improve During Pregnancy? A Systematic Review and Metaanalysis.

Jethwa H, Lam S, Smith C, Giles I.

J Rheumatol. 2019 Mar;46(3):245-250. doi: 10.3899/jrheum.180226. Epub 2018 Nov 1.

PMID:
30385703
13.

Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I.

McDonnell T, Artim-Esen B, Wincup C, Ripoll VM, Isenberg D, Giles IP, Rahman A, Pericleous C.

Front Immunol. 2018 Sep 28;9:2244. doi: 10.3389/fimmu.2018.02244. eCollection 2018.

14.

Safety of anti-rheumatic drugs in men trying to conceive: A systematic review and analysis of published evidence.

Mouyis M, Flint JD, Giles IP.

Semin Arthritis Rheum. 2019 Apr;48(5):911-920. doi: 10.1016/j.semarthrit.2018.07.011. Epub 2018 Aug 17.

PMID:
30220537
15.

Gene expression profiling identifies distinct molecular signatures in thrombotic and obstetric antiphospholipid syndrome.

Ripoll VM, Pregnolato F, Mazza S, Bodio C, Grossi C, McDonnell T, Pericleous C, Meroni PL, Isenberg DA, Rahman A, Giles IP.

J Autoimmun. 2018 Sep;93:114-123. doi: 10.1016/j.jaut.2018.07.002. Epub 2018 Jul 19.

16.

Effect of counter-ion on packing and crystal density of 5,5'-(3,3'-bi[1,2,4-oxa-diazole]-5,5'-di-yl)bis-(1H-tetra-zol-1-olate) with five different cations.

Giles ID, DeHope AJ, Zuckerman NB, Parrish DA, Pagoria PF.

Acta Crystallogr E Crystallogr Commun. 2018 Mar 9;74(Pt 4):505-513. doi: 10.1107/S205698901800364X. eCollection 2018 Apr 1.

17.

Two CuII complexes of 3,4,5-tri-methyl-1H-pyrazole.

Vincent CJ, Giles ID, Deschamps JR.

Acta Crystallogr E Crystallogr Commun. 2018 Feb 16;74(Pt 3):357-362. doi: 10.1107/S2056989018002359. eCollection 2018 Mar 1.

18.

Continuously tunable orbital angular momentum generation controlled by input linear polarization.

Wu S, Li Y, Feng L, Zeng X, Li W, Qiu J, Zuo Y, Hong X, Yu H, Chen R, Giles IP, Wu J.

Opt Lett. 2018 May 1;43(9):2130-2133. doi: 10.1364/OL.43.002130.

PMID:
29714763
19.

Comparison of ESSDAI and ClinESSDAI in potential optimisation of trial outcomes in primary Sjögren's syndrome: examination of data from the UK Primary Sjögren's Syndrome Registry.

Dumusc A, Ng WF, James K, Griffiths B, Price E, Pease C, Emery P, Lanyon P, Jones A, Bombardieri M, Sutcliffe N, Pitzalis C, Gupta M, McLaren J, Cooper A, Giles I, Isenberg D, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Barone F, Fisher B, Rauz S, Richards A, Bowman S.

Swiss Med Wkly. 2018 Feb 7;148:w14588. doi: 10.4414/smw.2018.14588. eCollection 2018.

20.

Going viral in rheumatology: using social media to show that mechanistic research is relevant to patients with lupus and antiphospholipid syndrome.

McDonnell TCR, Wincup C, Rahman A, Giles I.

Rheumatol Adv Pract. 2018;2(1):rky003. doi: 10.1093/rap/rky003. Epub 2018 Mar 5.

21.

Nitrated nucleosome levels and neuropsychiatric events in systemic lupus erythematosus; a multi-center retrospective case-control study.

Ferreira I, Croca S, Raimondo MG, Matharu M, Miller S, Giles I, Isenberg D, Ioannou Y, Hanly JG, Urowitz MB, Anderson N, Aranow C, Askanase A, Bae SC, Bernatsky S, Bruce IN, Buyon J, Clarke AE, Dooley MA, Fortin P, Ginzler E, Gladman D, Gordon C, Inanc M, Jacobsen S, Kalunian K, Kamen D, Khamashta M, Lim S, Manzi S, Merrill J, Nived O, Peschken C, Petri M, Ramsey-Goldman R, Ruiz-Irastorza G, Sanchez-Guerrero J, Steinson K, Sturfelt GK, van Vollenhoven R, Wallace DJ, Zoma A, Rahman A.

Arthritis Res Ther. 2017 Dec 22;19(1):287. doi: 10.1186/s13075-017-1495-6.

22.

Association between Systemic Lupus Erythematosus and Periodontitis: A Systematic Review and Meta-analysis.

Rutter-Locher Z, Smith TO, Giles I, Sofat N.

Front Immunol. 2017 Oct 17;8:1295. doi: 10.3389/fimmu.2017.01295. eCollection 2017.

23.

Oxidation of β2-glycoprotein I associates with IgG antibodies to domain I in patients with antiphospholipid syndrome.

Raimondo MG, Pericleous C, Radziszewska A, Borghi MO, Pierangeli S, Meroni PL, Giles I, Rahman A, Ioannou Y.

PLoS One. 2017 Oct 19;12(10):e0186513. doi: 10.1371/journal.pone.0186513. eCollection 2017.

24.

Eligibility for clinical trials in primary Sjögren's syndrome: lessons from the UK Primary Sjögren's Syndrome Registry.

Oni C, Mitchell S, James K, Ng WF, Griffiths B, Hindmarsh V, Price E, Pease CT, Emery P, Lanyon P, Jones A, Bombardieri M, Sutcliffe N, Pitzalis C, Hunter J, Gupta M, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Barone F, Fisher B, Rauz S, Richards A, Bowman SJ.

Rheumatology (Oxford). 2017 Dec 1;56(12):2255. doi: 10.1093/rheumatology/kex331. No abstract available.

25.

Large-bandwidth, low-loss, efficient mode mixing using long-period mechanical gratings.

Huang B, Chen H, Fontaine NK, Ryf R, Giles I, Li G.

Opt Lett. 2017 Sep 15;42(18):3594-3597. doi: 10.1364/OL.42.003594.

PMID:
28914910
26.

Factor Xa Mediates Calcium Flux in Endothelial Cells and is Potentiated by Igg From Patients With Lupus and/or Antiphospholipid Syndrome.

Artim-Esen B, Smoktunowicz N, McDonnell T, Ripoll VM, Pericleous C, Mackie I, Robinson E, Isenberg D, Rahman A, Ioannou Y, Chambers RC, Giles I.

Sci Rep. 2017 Sep 7;7(1):10788. doi: 10.1038/s41598-017-11315-9.

27.

Randomized Controlled Trial of Rituximab and Cost-Effectiveness Analysis in Treating Fatigue and Oral Dryness in Primary Sjögren's Syndrome.

Bowman SJ, Everett CC, O'Dwyer JL, Emery P, Pitzalis C, Ng WF, Pease CT, Price EJ, Sutcliffe N, Gendi NST, Hall FC, Ruddock SP, Fernandez C, Reynolds C, Hulme CT, Davies KA, Edwards CJ, Lanyon PC, Moots RJ, Roussou E, Giles IP, Sharples LD, Bombardieri M.

Arthritis Rheumatol. 2017 Jul;69(7):1440-1450. doi: 10.1002/art.40093. Epub 2017 Jun 5.

28.

Antiphospholipid antibodies enhance rat neonatal cardiomyocyte apoptosis in an in vitro hypoxia/reoxygenation injury model via p38 MAPK.

Bourke LT, McDonnell T, McCormick J, Pericleous C, Ripoll VM, Giles I, Rahman A, Stephanou A, Ioannou Y.

Cell Death Dis. 2017 Jan 12;8(1):e2549. doi: 10.1038/cddis.2016.235.

29.

Pregnancy Outcomes in Patients with Psoriatic Arthritis.

Mouyis MA, Thornton CC, Williams D, Giles IP.

J Rheumatol. 2017 Jan;44(1):128-129. doi: 10.3899/jrheum.160929. No abstract available.

PMID:
28042130
30.

Physical activity but not sedentary activity is reduced in primary Sjögren's syndrome.

Ng WF, Miller A, Bowman SJ, Price EJ, Kitas GD, Pease C, Emery P, Lanyon P, Hunter J, Gupta M, Giles I, Isenberg D, McLaren J, Regan M, Cooper A, Young-Min SA, McHugh N, Vadivelu S, Moots RJ, Coady D, MacKay K, Dasgupta B, Sutcliffe N, Bombardieri M, Pitzalis C, Griffiths B, Mitchell S, Miyamoto ST, Trenell M; UK Primary Sjögren’s Syndrome Registry.

Rheumatol Int. 2017 Apr;37(4):623-631. doi: 10.1007/s00296-016-3637-6. Epub 2016 Dec 24.

31.

Subjective and Objective Measures of Dryness Symptoms in Primary Sjögren's Syndrome: Capturing the Discrepancy.

Bezzina OM, Gallagher P, Mitchell S, Bowman SJ, Griffiths B, Hindmarsh V, Hargreaves B, Price EJ, Pease CT, Emery P, Lanyon P, Bombardieri M, Sutcliffe N, Pitzalis C, Hunter J, Gupta M, McLaren J, Cooper AM, Regan M, Giles IP, Isenberg DA, Saravanan V, Coady D, Dasgupta B, McHugh NJ, Young-Min SA, Moots RJ, Gendi N, Akil M, MacKay K, Ng WF, Robinson LJ; UK Primary Sjögren's Syndrome Registry.

Arthritis Care Res (Hoboken). 2017 Nov;69(11):1714-1723. doi: 10.1002/acr.23165. Epub 2017 Oct 9.

32.

Fatigue in primary Sjögren's syndrome is associated with lower levels of proinflammatory cytokines.

Howard Tripp N, Tarn J, Natasari A, Gillespie C, Mitchell S, Hackett KL, Bowman SJ, Price E, Pease CT, Emery P, Lanyon P, Hunter J, Gupta M, Bombardieri M, Sutcliffe N, Pitzalis C, McLaren J, Cooper A, Regan M, Giles I, Isenberg DA, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Griffiths B, Lendrem DW, Ng WF.

RMD Open. 2016 Jul 19;2(2):e000282. doi: 10.1136/rmdopen-2016-000282. eCollection 2016.

33.

Characterization of Rayleigh backscattering arising in various two-mode fibers.

Yu D, Fu S, Cao Z, Tang M, Deng L, Liu D, Giles I, Koonen T, Okonkwo C.

Opt Express. 2016 May 30;24(11):12192-201. doi: 10.1364/OE.24.012192.

PMID:
27410137
34.

The association between IgG and IgM antibodies against cardiolipin, β2-glycoprotein I and Domain I of β2-glycoprotein I with disease profile in patients with multiple sclerosis.

Filippidou N, Krashias G, Pericleous C, Rahman A, Ioannou Y, Giles I, Demetriou C, Anatolitou A, Christodoulou C, Pantzaris M, Lambrianides A.

Mol Immunol. 2016 Jul;75:161-7. doi: 10.1016/j.molimm.2016.05.022. Epub 2016 Jun 9.

PMID:
27289032
35.

Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome.

Pericleous C, Ferreira I, Borghi O, Pregnolato F, McDonnell T, Garza-Garcia A, Driscoll P, Pierangeli S, Isenberg D, Ioannou Y, Giles I, Meroni PL, Rahman A.

PLoS One. 2016 Jun 2;11(6):e0156407. doi: 10.1371/journal.pone.0156407. eCollection 2016.

36.

Mode-dependent characterization of photonic lanterns.

Yu D, Fu S, Cao Z, Tang M, Liu D, Giles I, Koonen T, Okonkwo C.

Opt Lett. 2016 May 15;41(10):2302-5. doi: 10.1364/OL.41.002302.

PMID:
27176988
37.

BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding-Part II: analgesics and other drugs used in rheumatology practice.

Flint J, Panchal S, Hurrell A, van de Venne M, Gayed M, Schreiber K, Arthanari S, Cunningham J, Flanders L, Moore L, Crossley A, Purushotham N, Desai A, Piper M, Nisar M, Khamashta M, Williams D, Gordon C, Giles I; BSR and BHPR Standards, Guidelines and Audit Working Group.

Rheumatology (Oxford). 2016 Sep;55(9):1698-702. doi: 10.1093/rheumatology/kev405. Epub 2016 Jan 10. No abstract available.

PMID:
26750125
38.

BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding-Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids.

Flint J, Panchal S, Hurrell A, van de Venne M, Gayed M, Schreiber K, Arthanari S, Cunningham J, Flanders L, Moore L, Crossley A, Purushotham N, Desai A, Piper M, Nisar M, Khamashta M, Williams D, Gordon C, Giles I; BSR and BHPR Standards, Guidelines and Audit Working Group.

Rheumatology (Oxford). 2016 Sep;55(9):1693-7. doi: 10.1093/rheumatology/kev404. Epub 2016 Jan 10. No abstract available.

PMID:
26750124
39.

A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome.

James K, Al-Ali S, Tarn J, Cockell SJ, Gillespie CS, Hindmarsh V, Locke J, Mitchell S, Lendrem D, Bowman S, Price E, Pease CT, Emery P, Lanyon P, Hunter JA, Gupta M, Bombardieri M, Sutcliffe N, Pitzalis C, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Griffiths B; UK Primary Sjögren’s Syndrome registry, Wipat A, Newton J, Jones DE, Isaacs J, Hallinan J, Ng WF.

PLoS One. 2015 Dec 22;10(12):e0143970. doi: 10.1371/journal.pone.0143970. eCollection 2015.

40.

Development of a high yield expression and purification system for Domain I of Beta-2-glycoprotein I for the treatment of APS.

McDonnell T, Pericleous C, Laurine E, Tommasi R, Garza-Garcia A, Giles I, Ioannou Y, Rahman A.

BMC Biotechnol. 2015 Nov 14;15:104. doi: 10.1186/s12896-015-0222-0.

41.

Eligibility for clinical trials in primary Sjögren's syndrome: lessons from the UK Primary Sjögren's Syndrome Registry.

Oni C, Mitchell S, James K, Ng WF, Griffiths B, Hindmarsh V, Price E, Pease CT, Emery P, Lanyon P, Jones A, Bombardieri M, Sutcliffe N, Pitzalis C, Hunter J, Gupta M, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Barone F, Fisher B, Rauz S, Richards A, Bowman SJ; UK Primary Sjögren’s Syndrome Registry.

Rheumatology (Oxford). 2016 Mar;55(3):544-52. doi: 10.1093/rheumatology/kev373. Epub 2015 Oct 27. Erratum in: Rheumatology (Oxford). 2017 Dec 1;56(12 ):2255.

42.

Examining the prevalence of non-criteria anti-phospholipid antibodies in patients with anti-phospholipid syndrome: a systematic review.

Rodríguez-García V, Ioannou Y, Fernández-Nebro A, Isenberg DA, Giles IP.

Rheumatology (Oxford). 2015 Nov;54(11):2042-50. doi: 10.1093/rheumatology/kev226. Epub 2015 Jul 7. Review.

PMID:
26152548
43.

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study.

Croca S, Bassett P, Chambers S, Davari M, Alber KF, Leach O, Ioannou Y, Giles I, Isenberg D, Rahman A.

Arthritis Res Ther. 2015 Feb 9;17:26. doi: 10.1186/s13075-015-0539-z.

44.

Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays.

Artim-Esen B, Pericleous C, Mackie I, Ripoll VM, Latchman D, Isenberg D, Rahman A, Ioannou Y, Giles I.

Arthritis Res Ther. 2015 Mar 7;17:47. doi: 10.1186/s13075-015-0568-7.

45.

Poor adherence to guidelines on early management of acute hot swollen joint(s): an evaluation of clinical practice and implications for training.

Farah Z, Reddy V, Matthews W, Giles I.

Int J Clin Pract. 2015 May;69(5):618-22. doi: 10.1111/ijcp.12580. Epub 2015 Feb 4.

PMID:
25650874
46.

Purified IgG from patients with obstetric but not IgG from non-obstetric antiphospholipid syndrome inhibit trophoblast invasion.

Poulton K, Ripoll VM, Pericleous C, Meroni PL, Gerosa M, Ioannou Y, Rahman A, Giles IP.

Am J Reprod Immunol. 2015 May;73(5):390-401. doi: 10.1111/aji.12341. Epub 2014 Dec 2.

47.

Brain abnormalities in newly diagnosed neuropsychiatric lupus: systematic MRI approach and correlation with clinical and laboratory data in a large multicenter cohort.

Sarbu N, Alobeidi F, Toledano P, Espinosa G, Giles I, Rahman A, Yousry T, Capurro S, Jäger R, Cervera R, Bargalló N.

Autoimmun Rev. 2015 Feb;14(2):153-9. doi: 10.1016/j.autrev.2014.11.001. Epub 2014 Nov 8. Review.

PMID:
25461835
48.

Antibodies to domain I of β-2-glycoprotein I and IgA antiphospholipid antibodies in patients with 'seronegative' antiphospholipid syndrome.

Cousins L, Pericleous C, Khamashta M, Bertolaccini ML, Ioannou Y, Giles I, Rahman A.

Ann Rheum Dis. 2015 Jan;74(1):317-9. doi: 10.1136/annrheumdis-2014-206483. Epub 2014 Oct 30. No abstract available.

49.

Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome.

Ripoll VM, Lambrianides A, Pierangeli SS, Poulton K, Ioannou Y, Heywood WE, Mills K, Latchman DS, Isenberg DA, Rahman A, Giles IP.

Blood. 2014 Dec 11;124(25):3808-16. doi: 10.1182/blood-2014-05-577569. Epub 2014 Oct 9.

50.

Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis.

Pericleous C, Ruiz-Limón P, Romay-Penabad Z, Marín AC, Garza-Garcia A, Murfitt L, Driscoll PC, Latchman DS, Isenberg DA, Giles I, Ioannou Y, Rahman A, Pierangeli SS.

Rheumatology (Oxford). 2015 Apr;54(4):722-7. doi: 10.1093/rheumatology/keu360. Epub 2014 Sep 30.

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