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Items: 40

1.

Inhalation of Bacterial Cellulose Nanofibrils Triggers an Inflammatory Response and Changes Lung Tissue Morphology of Mice.

Silva-Carvalho R, Silva JP, Ferreirinha P, Leitão AF, Andrade FK, Gil da Costa RM, Cristelo C, Rosa MF, Vilanova M, Gama FM.

Toxicol Res. 2019 Jan;35(1):45-63. doi: 10.5487/TR.2019.35.1.045. Epub 2018 Jan 15.

2.

Hallmarks of HPV carcinogenesis: The role of E6, E7 and E5 oncoproteins in cellular malignancy.

Estêvão D, Costa NR, Gil da Costa RM, Medeiros R.

Biochim Biophys Acta Gene Regul Mech. 2019 Feb;1862(2):153-162. doi: 10.1016/j.bbagrm.2019.01.001. Epub 2019 Jan 29. Review.

PMID:
30707946
3.

The Role of MicroRNAs in the Metastatic Process of High-Risk HPV-Induced Cancers.

Santos JMO, Peixoto da Silva S, Costa NR, Gil da Costa RM, Medeiros R.

Cancers (Basel). 2018 Dec 5;10(12). pii: E493. doi: 10.3390/cancers10120493. Review.

4.

The Aged Microenvironment Influences the Tumorigenic Potential of Malignant Prostate Epithelial Cells.

Bianchi-Frias D, Damodarasamy M, Hernandez SA, Gil da Costa RM, Vakar-Lopez F, Coleman IM, Reed MJ, Nelson PS.

Mol Cancer Res. 2019 Jan;17(1):321-331. doi: 10.1158/1541-7786.MCR-18-0522. Epub 2018 Sep 17.

PMID:
30224545
5.

Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice.

Medeiros-Fonseca B, Mestre VF, Colaço B, Pires MJ, Martins T, Gil da Costa RM, Neuparth MJ, Medeiros R, Moutinho MSS, Dias MI, Barros L, Bastos MMSM, Félix L, Venâncio C, Ferreira ICFR, Antunes LM, Oliveira PA.

Food Funct. 2018 Aug 15;9(8):4419-4428. doi: 10.1039/c8fo00783g.

PMID:
30066000
6.

Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis.

Peirone C, Mestre VF, Medeiros-Fonseca B, Colaço B, Pires MJ, Martins T, Gil da Costa RM, Neuparth MJ, Medeiros R, Bastos MMSM, Marques-Magallanes JA, Oliveira PA.

Biomed Pharmacother. 2018 Aug;104:275-279. doi: 10.1016/j.biopha.2018.05.018. Epub 2018 May 25.

PMID:
29775895
7.

A viral map of gastrointestinal cancers.

Costa NR, Gil da Costa RM, Medeiros R.

Life Sci. 2018 Apr 15;199:188-200. doi: 10.1016/j.lfs.2018.02.025. Epub 2018 Feb 21. Review.

PMID:
29476768
8.

Dysregulation of cellular microRNAs by human oncogenic viruses - Implications for tumorigenesis.

Santos JMO, Gil da Costa RM, Medeiros R.

Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):95-105. doi: 10.1016/j.bbagrm.2018.01.017. Epub 2018 Jan 31. Review.

PMID:
29378330
9.

Carcinocythemia: First report in a cat and literature review.

Sá E Lemos E, Lima de Carvalho H, Gil da Costa RM, Pinto da Cunha N.

Vet Clin Pathol. 2018 Mar;47(1):142-145. doi: 10.1111/vcp.12565. Epub 2018 Jan 23. Review.

PMID:
29360147
10.

Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice.

Araújo R, Santos JMO, Fernandes M, Dias F, Sousa H, Ribeiro J, Bastos MMSM, Oliveira PA, Carmo D, Casaca F, Silva S, Medeiros R, Gil da Costa RM.

J Cancer Res Clin Oncol. 2018 Feb;144(2):241-248. doi: 10.1007/s00432-017-2549-5. Epub 2017 Nov 27.

PMID:
29181576
11.

The N-butyl-N-4-hydroxybutyl Nitrosamine Mouse Urinary Bladder Cancer Model.

Oliveira PA, Vasconcelos-Nóbrega C, Gil da Costa RM, Arantes-Rodrigues R.

Methods Mol Biol. 2018;1655:155-167. doi: 10.1007/978-1-4939-7234-0_13. Review.

PMID:
28889385
12.

Effects of exercise training on breast cancer metastasis in a rat model.

Alvarado A, Gil da Costa RM, Faustino-Rocha AI, Ferreira R, Lopes C, Oliveira PA, Colaço B.

Int J Exp Pathol. 2017 Feb;98(1):40-46. doi: 10.1111/iep.12225.

13.

HPV-transgenic mouse models: Tools for studying the cancer-associated immune response.

Santos C, Vilanova M, Medeiros R, Gil da Costa RM.

Virus Res. 2017 May 2;235:49-57. doi: 10.1016/j.virusres.2017.04.001. Epub 2017 Apr 3. Review.

PMID:
28385491
14.

Dysregulated expression of microRNA-150 in human papillomavirus-induced lesions of K14-HPV16 transgenic mice.

Santos JMO, Fernandes M, Araújo R, Sousa H, Ribeiro J, Bastos MMSM, Oliveira PA, Carmo D, Casaca F, Silva S, Teixeira AL, Gil da Costa RM, Medeiros R.

Life Sci. 2017 Apr 15;175:31-36. doi: 10.1016/j.lfs.2017.03.008. Epub 2017 Mar 14.

PMID:
28302562
15.

HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-κB inhibition.

Gil da Costa RM, Aragão S, Moutinho M, Alvarado A, Carmo D, Casaca F, Silva S, Ribeiro J, Sousa H, Ferreira R, Nogueira-Ferreira R, Pires MJ, Colaço B, Medeiros R, Venâncio C, Oliveira MM, Bastos MM, Lopes C, Oliveira PA.

Life Sci. 2017 Jan 15;169:11-19. doi: 10.1016/j.lfs.2016.10.031. Epub 2016 Nov 22.

PMID:
27888116
16.

Ptaquiloside from bracken (Pteridium spp.) inhibits tumour-infiltrating CD8+ T cells in HPV-16 transgenic mice.

Santos C, Ferreirinha P, Sousa H, Ribeiro J, Bastos MM, Neto T, Oliveira PA, Medeiros R, Vilanova M, Gil da Costa RM.

Food Chem Toxicol. 2016 Nov;97:277-285. doi: 10.1016/j.fct.2016.09.019. Epub 2016 Sep 15.

PMID:
27640346
17.

An Update on Canine, Feline and Bovine Papillomaviruses.

Gil da Costa RM, Peleteiro MC, Pires MA, DiMaio D.

Transbound Emerg Dis. 2017 Oct;64(5):1371-1379. doi: 10.1111/tbed.12555. Epub 2016 Sep 11. Review.

PMID:
27615361
18.

Long-term exercise training as a modulator of mammary cancer vascularization.

Faustino-Rocha AI, Silva A, Gabriel J, Gil da Costa RM, Moutinho M, Oliveira PA, Gama A, Ferreira R, Ginja M.

Biomed Pharmacother. 2016 Jul;81:273-280. doi: 10.1016/j.biopha.2016.04.030. Epub 2016 Apr 22.

PMID:
27261604
19.

Challenges with in vitro and in vivo experimental models of urinary bladder cancer for novel drug discovery.

Oliveira PA, Gil da Costa RM, Vasconcelos-Nóbrega C, Arantes-Rodrigues R, Pinto-Leite R.

Expert Opin Drug Discov. 2016 Jun;11(6):599-607. doi: 10.1080/17460441.2016.1174690. Epub 2016 Apr 28. Review.

PMID:
27077499
20.

Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics.

Costa C, Pereira S, Lima L, Peixoto A, Fernandes E, Neves D, Neves M, Gaiteiro C, Tavares A, Gil da Costa RM, Cruz R, Amaro T, Oliveira PA, Ferreira JA, Santos LL.

PLoS One. 2015 Nov 16;10(11):e0141253. doi: 10.1371/journal.pone.0141253. eCollection 2015.

21.

Altered expression of CKs 14/20 is an early event in a rat model of multistep bladder carcinogenesis.

Gil da Costa RM, Oliveira PA, Vasconcelos-Nóbrega C, Arantes-Rodrigues R, Pinto-Leite R, Colaço AA, de la Cruz LF, Lopes C.

Int J Exp Pathol. 2015 Oct;96(5):319-25. doi: 10.1111/iep.12145. Epub 2015 Oct 30.

22.

C-kit as a prognostic and therapeutic marker in canine cutaneous mast cell tumours: From laboratory to clinic.

Gil da Costa RM.

Vet J. 2015 Jul;205(1):5-10. doi: 10.1016/j.tvjl.2015.05.002. Epub 2015 May 6. Review.

PMID:
26021891
23.

MicroRNA-21 expression and susceptibility to HPV-induced carcinogenesis - role of microenvironment in K14-HPV16 mice model.

Paiva I, Gil da Costa RM, Ribeiro J, Sousa H, Bastos MM, Faustino-Rocha A, Lopes C, Oliveira PA, Medeiros R.

Life Sci. 2015 May 1;128:8-14. doi: 10.1016/j.lfs.2015.02.020. Epub 2015 Mar 12. No abstract available.

PMID:
25771247
24.

A role for microRNA-155 expression in microenvironment associated to HPV-induced carcinogenesis in K14-HPV16 transgenic mice.

Paiva I, Gil da Costa RM, Ribeiro J, Sousa H, Bastos M, Faustino-Rocha A, Lopes C, Oliveira PA, Medeiros R.

PLoS One. 2015 Jan 27;10(1):e0116868. doi: 10.1371/journal.pone.0116868. eCollection 2015. Erratum in: PLoS One. 2015;10(7):e0134159. Rocha, Ana Faustino Carlos [corrected to Faustino-Rocha, Ana]; [corrected to Lopes, Carlos].

25.

N-diethylnitrosamine mouse hepatotoxicity: time-related effects on histology and oxidative stress.

Paula Santos N, Colaço A, Gil da Costa RM, Manuel Oliveira M, Peixoto F, Alexandra Oliveira P.

Exp Toxicol Pathol. 2014 Dec;66(9-10):429-36. doi: 10.1016/j.etp.2014.07.002. Epub 2014 Aug 2.

PMID:
25097018
26.

Cytokeratin 7/19 expression in N-diethylnitrosamine-induced mouse hepatocellular lesions: implications for histogenesis.

Santos NP, Oliveira PA, Arantes-Rodrigues R, Faustino-Rocha AI, Colaço A, Lopes C, Gil da Costa RM.

Int J Exp Pathol. 2014 Jun;95(3):191-8. doi: 10.1111/iep.12082. Epub 2014 Apr 15.

27.

Bovine papillomavirus: opening new trends for comparative pathology.

Gil da Costa RM, Medeiros R.

Arch Virol. 2014 Feb;159(2):191-8. doi: 10.1007/s00705-013-1801-9. Epub 2013 Aug 9. Review.

PMID:
23929231
28.

Sesquiterpene lactones: adverse health effects and toxicity mechanisms.

Amorim MH, Gil da Costa RM, Lopes C, Bastos MM.

Crit Rev Toxicol. 2013 Aug;43(7):559-79. doi: 10.3109/10408444.2013.813905. Review.

PMID:
23875764
29.

Ptaquiloside-induced early-stage urothelial lesions show increased cell proliferation and intact β-catenin and E-cadherin expression.

Gil da Costa RM, Oliveira PA, Bastos MM, Lopes CC, Lopes C.

Environ Toxicol. 2014 May;29(7):763-9. doi: 10.1002/tox.21803. Epub 2012 Aug 1.

PMID:
22859263
30.

Multiple genotoxic activities of ptaquiloside in human lymphocytes: aneugenesis, clastogenesis and induction of sister chromatid exchange.

Gil da Costa RM, Coelho P, Sousa R, Bastos MM, Porto B, Teixeira JP, Malheiro I, Lopes C.

Mutat Res. 2012 Aug 30;747(1):77-81. doi: 10.1016/j.mrgentox.2012.04.010. Epub 2012 Apr 28.

PMID:
22565221
31.

Bracken-associated human and animal health hazards: chemical, biological and pathological evidence.

Gil da Costa RM, Bastos MM, Oliveira PA, Lopes C.

J Hazard Mater. 2012 Feb 15;203-204:1-12. doi: 10.1016/j.jhazmat.2011.12.046. Epub 2011 Dec 24. Review.

PMID:
22226718
32.

Ptaquiloside-induced, B-cell lymphoproliferative and early-stage urothelial lesions in mice.

Gil da Costa RM, Oliveira PA, Vilanova M, Bastos MM, Lopes CC, Lopes C.

Toxicon. 2011 Nov;58(6-7):543-9. doi: 10.1016/j.toxicon.2011.08.016. Epub 2011 Sep 1.

PMID:
21907228
33.

Bacterial cellulose: long-term biocompatibility studies.

Pértile RA, Moreira S, Gil da Costa RM, Correia A, Guãrdao L, Gartner F, Vilanova M, Gama M.

J Biomater Sci Polym Ed. 2012;23(10):1339-54. doi: 10.1163/092050611X581516. Epub 2012 May 8.

PMID:
21722421
34.

In vitro and in vivo chitosan membranes testing for peripheral nerve reconstruction.

Simões MJ, Gärtner A, Shirosaki Y, Gil da Costa RM, Cortez PP, Gartnër F, Santos JD, Lopes MA, Geuna S, Varejão AS, Maurício AC.

Acta Med Port. 2011 Jan-Feb;24(1):43-52. Epub 2011 Feb 28.

35.

Immunohistochemical characterization of 13 canine renal cell carcinomas.

Gil da Costa RM, Oliveira JP, Saraiva AL, Seixas F, Faria F, Gärtner F, Pires MA, Lopes C.

Vet Pathol. 2011 Mar;48(2):427-32. doi: 10.1177/0300985810381909. Epub 2010 Sep 22.

PMID:
20861495
36.

Two canine Merkel cell tumours: immunoexpression of c-KIT, E-cadherin, beta-catenin and S100 protein.

Gil da Costa RM, Rema A, Pires MA, Gärtner F.

Vet Dermatol. 2010 Apr;21(2):198-201. doi: 10.1111/j.1365-3164.2009.00768.x. Epub 2009 Aug 4.

PMID:
19706008
37.

Leukocyte populations and cytokine expression in the mammary gland in a mouse model of Streptococcus agalactiae mastitis.

Trigo G, Dinis M, França A, Bonifácio Andrade E, Gil da Costa RM, Ferreira P, Tavares D.

J Med Microbiol. 2009 Jul;58(Pt 7):951-8. doi: 10.1099/jmm.0.007385-0. Epub 2009 Jun 4.

PMID:
19498204
38.

An immunohistochemical study of feline endometrial adenocarcinoma.

Gil da Costa RM, Santos M, Amorim I, Lopes C, Pereira PD, Faustino AM.

J Comp Pathol. 2009 May;140(4):254-9. doi: 10.1016/j.jcpa.2008.12.006. Epub 2009 Feb 7.

PMID:
19201419
39.

CD117 immunoexpression in canine mast cell tumours: correlations with pathological variables and proliferation markers.

Gil da Costa RM, Matos E, Rema A, Lopes C, Pires MA, Gärtner F.

BMC Vet Res. 2007 Aug 21;3:19.

40.

Immunohistochemical characterization of a sebaceous gland carcinoma in a gerbil (Meriones unguiculatus).

Gil da Costa RM, Rema A, Payo-Puente P, Gärtner F.

J Comp Pathol. 2007 Aug-Oct;137(2-3):130-2. Epub 2007 Jul 23.

PMID:
17645891

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