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Items: 37


CCNO mutations in NPH?

Núnez-Ollé M, Stracker TH, Gil-Gómez G.

Aging (Albany NY). 2018 Feb 3;10(2):158-159. doi: 10.18632/aging.101379. No abstract available.


Constitutive Cyclin O deficiency results in penetrant hydrocephalus, impaired growth and infertility.

Núnez-Ollé M, Jung C, Terré B, Balsiger NA, Plata C, Roset R, Pardo-Pastor C, Garrido M, Rojas S, Alameda F, Lloreta J, Martín-Caballero J, Flores JM, Stracker TH, Valverde MA, Muñoz FJ, Gil-Gómez G.

Oncotarget. 2017 Oct 12;8(59):99261-99273. doi: 10.18632/oncotarget.21818. eCollection 2017 Nov 21.


Defective Cyclin B1 Induction in Trastuzumab-emtansine (T-DM1) Acquired Resistance in HER2-positive Breast Cancer.

Sabbaghi M, Gil-Gómez G, Guardia C, Servitja S, Arpí O, García-Alonso S, Menendez S, Arumi-Uria M, Serrano L, Salido M, Muntasell A, Martínez-García M, Zazo S, Chamizo C, González-Alonso P, Madoz-Gúrpide J, Eroles P, Arribas J, Tusquets I, Lluch A, Pandiella A, Rojo F, Rovira A, Albanell J.

Clin Cancer Res. 2017 Nov 15;23(22):7006-7019. doi: 10.1158/1078-0432.CCR-17-0696. Epub 2017 Aug 18.


GEMC1 is a critical regulator of multiciliated cell differentiation.

Terré B, Piergiovanni G, Segura-Bayona S, Gil-Gómez G, Youssef SA, Attolini CS, Wilsch-Bräuninger M, Jung C, Rojas AM, Marjanović M, Knobel PA, Palenzuela L, López-Rovira T, Forrow S, Huttner WB, Valverde MA, de Bruin A, Costanzo V, Stracker TH.

EMBO J. 2016 May 2;35(9):942-60. doi: 10.15252/embj.201592821. Epub 2016 Mar 1.


Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death.

Ill-Raga G, Palomer E, Ramos-Fernández E, Guix FX, Bosch-Morató M, Guivernau B, Tajes M, Valls-Comamala V, Jiménez-Conde J, Ois A, Pérez-Asensio F, Reyes-Navarro M, Caballo C, Gil-Gómez G, Lopez-Vilchez I, Galan AM, Alameda F, Escolar G, Opazo C, Planas AM, Roquer J, Valverde MA, Muñoz FJ.

Biochim Biophys Acta. 2015 Mar;1852(3):421-8. doi: 10.1016/j.bbadis.2014.12.007. Epub 2014 Dec 12.


Methylglyoxal produced by amyloid-β peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in Alzheimer's disease.

Tajes M, Eraso-Pichot A, Rubio-Moscardó F, Guivernau B, Ramos-Fernández E, Bosch-Morató M, Guix FX, Clarimón J, Miscione GP, Boada M, Gil-Gómez G, Suzuki T, Molina H, Villà-Freixa J, Vicente R, Muñoz FJ.

J Alzheimers Dis. 2014;41(1):273-88. doi: 10.3233/JAD-131685.


Cooperative role between p21cip1/waf1 and p27kip1 in premature senescence in glandular proliferative lesions in mice.

García-Fernández RA, García-Palencia P, Suarez C, Sánchez MA, Gil-Gómez G, Sánchez B, Rollán E, Martín-Caballero J, Flores JM.

Histol Histopathol. 2014 Mar;29(3):397-406. doi: 10.14670/HH-29.397. Epub 2013 Sep 20.


Highly crosslinked polyethylene does not reduce the wear in total knee arthroplasty: in vivo study of particles in synovial fluid.

Hinarejos P, Piñol I, Torres A, Prats E, Gil-Gómez G, Puig-Verdie L.

J Arthroplasty. 2013 Sep;28(8):1333-7. doi: 10.1016/j.arth.2013.01.026. Epub 2013 Mar 16.


Combined loss of p21(waf1/cip1) and p27(kip1) enhances tumorigenesis in mice.

García-Fernández RA, García-Palencia P, Sánchez MÁ, Gil-Gómez G, Sánchez B, Rollán E, Martín-Caballero J, Flores JM.

Lab Invest. 2011 Nov;91(11):1634-42. doi: 10.1038/labinvest.2011.133. Epub 2011 Aug 29.


Measurement of changes in Cdk2 and cyclin o-associated kinase activity in apoptosis.

Roset R, Gil-Gómez G.

Methods Mol Biol. 2009;559:161-72. doi: 10.1007/978-1-60327-017-5_12.


Identification of a novel cyclin required for the intrinsic apoptosis pathway in lymphoid cells.

Roig MB, Roset R, Ortet L, Balsiger NA, Anfosso A, Cabellos L, Garrido M, Alameda F, Brady HJ, Gil-Gómez G.

Cell Death Differ. 2009 Feb;16(2):230-43. doi: 10.1038/cdd.2008.145. Epub 2008 Oct 17.


Role of Bcl-2 family members on apoptosis: what we have learned from knock-out mice.

Roset R, Ortet L, Gil-Gomez G.

Front Biosci. 2007 May 1;12:4722-30. Review.


Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis.

Clohessy JG, Zhuang J, de Boer J, Gil-Gómez G, Brady HJ.

J Biol Chem. 2006 Mar 3;281(9):5750-9. Epub 2005 Dec 27.


Cdk2 activation acts upstream of the mitochondrion during glucocorticoid induced thymocyte apoptosis.

Granés F, Roig MB, Brady HJ, Gil-Gómez G.

Eur J Immunol. 2004 Oct;34(10):2781-90.


Measurement of changes in apoptosis and cell cycle regulatory kinase Cdk2.

Gil-Gómez G.

Methods Mol Biol. 2004;282:131-44.


Transgenic mice in apoptosis research.

Gil-Gómez G, Brady HJ.

Apoptosis. 1998 Sep;3(4):215-28.


Vitamin E but not 17beta-estradiol protects against vascular toxicity induced by beta-amyloid wild type and the Dutch amyloid variant.

Muñoz FJ, Opazo C, Gil-Gómez G, Tapia G, Fernández V, Valverde MA, Inestrosa NC.

J Neurosci. 2002 Apr 15;22(8):3081-9.


Activation of Cdk2 is a requirement for antigen-mediated thymic negative selection.

Williams O, Gil-Gómez G, Norton T, Kioussis D, Brady HJ.

Eur J Immunol. 2000 Feb;30(2):709-13.


The role of the tumor suppressor p53 in spermatogenesis.

Beumer TL, Roepers-Gajadien HL, Gademan IS, van Buul PP, Gil-Gomez G, Rutgers DH, de Rooij DG.

Cell Death Differ. 1998 Aug;5(8):669-77.


The cell cycle and apoptosis.

Brady HJ, Gil-Gómez G.

Results Probl Cell Differ. 1999;23:127-44. Review. No abstract available.


Bad can act as a key regulator of T cell apoptosis and T cell development.

Mok CL, Gil-Gómez G, Williams O, Coles M, Taga S, Tolaini M, Norton T, Kioussis D, Brady HJ.

J Exp Med. 1999 Feb 1;189(3):575-86.


Bax. The pro-apoptotic Bcl-2 family member, Bax.

Brady HJ, Gil-Gómez G.

Int J Biochem Cell Biol. 1998 Jun;30(6):647-50. Review.


Bax alpha perturbs T cell development and affects cell cycle entry of T cells.

Brady HJ, Gil-Gómez G, Kirberg J, Berns AJ.

EMBO J. 1996 Dec 16;15(24):6991-7001.


Immunolocalization of mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase in rat liver.

Royo T, Pedragosa MJ, Ayté J, Gil-Gómez G, Vilaró S, Hegardt FG.

J Cell Physiol. 1995 Jan;162(1):103-9.


Transfection of the ketogenic mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase cDNA into Mev-1 cells corrects their auxotrophy for mevalonate.

Ortiz JA, Gil-Gómez G, Casaroli-Marano RP, Vilaró S, Hegardt FG, Haro D.

J Biol Chem. 1994 Nov 18;269(46):28523-6.


Gene expression of enzymes regulating ketogenesis and fatty acid metabolism in regenerating rat liver.

Asins G, Rosa JL, Serra D, Gil-Gómez G, Ayté J, Bartrons R, Tauler A, Hegardt FG.

Biochem J. 1994 Apr 1;299 ( Pt 1):65-9.


Testis and ovary express the gene for the ketogenic mitochondrial 3- hydroxy-3-methylglutaryl-CoA synthase.

Royo T, Pedragosa MJ, Ayté J, Gil-Gómez G, Vilaró S, Hegardt FG.

J Lipid Res. 1993 Sep;34(9):1636. No abstract available.


Testis and ovary express the gene for the ketogenic mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase.

Royo T, Pedragosa MJ, Ayté J, Gil-Gómez G, Vilaró S, Hegardt FG.

J Lipid Res. 1993 Jun;34(6):867-74. Erratum in: J Lipid Res. 1993 Sep;34(9):1636.


Regulation of the expression of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene. Its role in the control of ketogenesis.

Casals N, Roca N, Guerrero M, Gil-Gómez G, Ayté J, Ciudad CJ, Hegardt FG.

Biochem J. 1992 Apr 1;283 ( Pt 1):261-4.


Characterization of the gene encoding the 10 kDa polypeptide of photosystem II from Arabidopsis thaliana.

Gil-Gómez G, Marrero PF, Haro D, Ayté J, Hegardt FG.

Plant Mol Biol. 1991 Sep;17(3):517-22.


Nucleotide sequence of a rat liver cDNA encoding the cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase.

Ayté J, Gil-Gómez G, Hegardt FG.

Nucleic Acids Res. 1990 Jun 25;18(12):3642. No abstract available.


Rat mitochondrial and cytosolic 3-hydroxy-3-methylglutaryl-CoA synthases are encoded by two different genes.

Ayté J, Gil-Gómez G, Haro D, Marrero PF, Hegardt FG.

Proc Natl Acad Sci U S A. 1990 May;87(10):3874-8.

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