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Combined Reconstruction of the Anterolateral Ligament in Patients With Anterior Cruciate Ligament Injury and Ligamentous Hyperlaxity Leads to Better Clinical Stability and a Lower Failure Rate Than Isolated Anterior Cruciate Ligament Reconstruction.

Helito CP, Sobrado MF, Giglio PN, Bonadio MB, Pécora JR, Camanho GL, Demange MK.

Arthroscopy. 2019 Sep;35(9):2648-2654. doi: 10.1016/j.arthro.2019.03.059. Epub 2019 Aug 14.


Clinical Outcomes of Posterolateral Complex Reconstruction Performed with a Single Femoral Tunnel.

Helito CP, Sobrado MF, Giglio PN, Bonadio MB, Pécora JR, Gobbi RG, Camanho GL, Angelini FJ.

J Knee Surg. 2019 Jul 9. doi: 10.1055/s-0039-1693003. [Epub ahead of print]


Early assessment of recurrent glioblastoma response to bevacizumab treatment by diffusional kurtosis imaging: a preliminary report.

Lee CY, Kalra A, Spampinato MV, Tabesh A, Jensen JH, Helpern JA, de Fatima Falangola M, Van Horn MH, Giglio P.

Neuroradiol J. 2019 Oct;32(5):317-327. doi: 10.1177/1971400919861409. Epub 2019 Jul 8.


Spinal Cord Toxicity from Intrathecal Chemotherapy: A Case with Clinicopathologic Correlation.

Dornbos D 3rd, Elder JB, Otero JJ, Baiocchi RA, Slone HW, Puduvalli VK, Giglio P.

World Neurosurg. 2019 May 22. pii: S1878-8750(19)31400-7. doi: 10.1016/j.wneu.2019.05.123. [Epub ahead of print]


Changing paradigms for targeted therapies against diffuse infiltrative gliomas: tackling a moving target.

Carpenter CD, Alnahhas I, Gonzalez J, Giglio P, Puduvalli VK.

Expert Rev Neurother. 2019 Jul;19(7):663-677. doi: 10.1080/14737175.2019.1621169. Epub 2019 May 27.


Treatment of Glioblastoma (GBM) with the Addition of Tumor-Treating Fields (TTF): A Review.

Fabian D, Guillermo Prieto Eibl MDP, Alnahhas I, Sebastian N, Giglio P, Puduvalli V, Gonzalez J, Palmer JD.

Cancers (Basel). 2019 Feb 2;11(2). pii: E174. doi: 10.3390/cancers11020174. Review.


Posterolateral reconstruction combined with one-stage tibial valgus osteotomy: Technical considerations and functional results.

Helito CP, Sobrado MF, Giglio PN, Bonadio MB, Demange MK, Pécora JR, Camanho GL, Angelini FJ.

Knee. 2019 Mar;26(2):500-507. doi: 10.1016/j.knee.2018.12.001. Epub 2019 Jan 8.


Ecto-Calreticulin is essential for an efficient immunogenic cell death stimulation in mouse melanoma.

Giglio P, Gagliardi M, Bernardini R, Mattei M, Cotella D, Santoro C, Piacentini M, Corazzari M.

Genes Immun. 2019 Jul;20(6):509-513. doi: 10.1038/s41435-018-0047-7. Epub 2018 Oct 4.


PKR and GCN2 stress kinases promote an ER stress-independent eIF2α phosphorylation responsible for calreticulin exposure in melanoma cells.

Giglio P, Gagliardi M, Tumino N, Antunes F, Smaili S, Cotella D, Santoro C, Bernardini R, Mattei M, Piacentini M, Corazzari M.

Oncoimmunology. 2018 May 31;7(8):e1466765. doi: 10.1080/2162402X.2018.1466765. eCollection 2018.


Single agent efficacy of the HDAC inhibitor DATS in preclinical models of glioblastoma.

Das A, Henderson F Jr, Lowe S, Wallace GC 4th, Vandergrift WA 3rd, Lindhorst SM, Varma AK, Infinger LK, Giglio P, Banik NL, Patel SJ, Cachia D.

Cancer Chemother Pharmacol. 2018 Dec;82(6):945-952. doi: 10.1007/s00280-018-3684-7. Epub 2018 Sep 12.


Epidemiology of Upper Extremity Soccer Injuries Among High School- and College-Aged Players in the United States: An Analysis of the 1999-2016 NEISS Database.

Durand WM, Goodman AD, Giglio P, Etzel C, Owens BD.

Sports Health. 2018 Nov/Dec;10(6):552-557. doi: 10.1177/1941738118795483. Epub 2018 Sep 5.


Perilesional apparent diffusion coefficient in the preoperative evaluation of glioma grade.

Yazdani M, Rumboldt Z, Tabesh A, Giglio P, Schiarelli C, Morgan PS, Spampinato MV.

Clin Imaging. 2018 Nov - Dec;52:88-94. doi: 10.1016/j.clinimag.2018.07.005. Epub 2018 Jul 7.


Knee arthroplasty with rotating-hinge implant: an option for complex primary cases and revisions.

Helito CP, Giglio PN, Cavalheiro CM, Gobbi RG, Demange MK, Camanho GL.

Rev Bras Ortop. 2018 Feb 21;53(2):151-157. doi: 10.1016/j.rboe.2017.01.010. eCollection 2018 Mar-Apr.


Combined reconstruction of the anterolateral ligament in chronic ACL injuries leads to better clinical outcomes than isolated ACL reconstruction.

Helito CP, Camargo DB, Sobrado MF, Bonadio MB, Giglio PN, Pécora JR, Camanho GL, Demange MK.

Knee Surg Sports Traumatol Arthrosc. 2018 Dec;26(12):3652-3659. doi: 10.1007/s00167-018-4934-2. Epub 2018 Apr 2.


Increased cytokine levels and histological changes in cartilage, synovial cells and synovial fluid after malleolar fractures.

Godoy-Santos AL, Ranzoni L, Teodoro WR, Capelozzi V, Giglio P, Fernandes TD, Rammelt S.

Injury. 2017 Oct;48 Suppl 4:S27-S33. doi: 10.1016/S0020-1383(17)30772-6.


Subchondroplasty for treating bone marrow lesions in the knee - initial experience.

Bonadio MB, Giglio PN, Helito CP, Pécora JR, Camanho GL, Demange MK.

Rev Bras Ortop. 2017 Apr 28;52(3):325-330. doi: 10.1016/j.rboe.2017.04.003. eCollection 2017 May-Jun.



Helito CP, Bueno DK, Giglio PN, Bonadio MB, Pécora JR, Demange MK.

Acta Ortop Bras. 2017 Mar-Apr;25(2):85-88. doi: 10.1590/1413-785220172502169053.


Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus.

Liu J, Ghneim K, Sok D, Bosche WJ, Li Y, Chipriano E, Berkemeier B, Oswald K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, Jimenez J, Mondesir J, Lee B, Giglio P, Chandrashekar A, Abbink P, Colantonio A, Gittens C, Baker C, Wagner W, Lewis MG, Li W, Sekaly RP, Lifson JD, Burton DR, Barouch DH.

Science. 2016 Sep 2;353(6303):1045-1049. Epub 2016 Aug 18.


Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys.

Abbink P, Larocca RA, De La Barrera RA, Bricault CA, Moseley ET, Boyd M, Kirilova M, Li Z, Ng'ang'a D, Nanayakkara O, Nityanandam R, Mercado NB, Borducchi EN, Agarwal A, Brinkman AL, Cabral C, Chandrashekar A, Giglio PB, Jetton D, Jimenez J, Lee BC, Mojta S, Molloy K, Shetty M, Neubauer GH, Stephenson KE, Peron JP, Zanotto PM, Misamore J, Finneyfrock B, Lewis MG, Alter G, Modjarrad K, Jarman RG, Eckels KH, Michael NL, Thomas SJ, Barouch DH.

Science. 2016 Sep 9;353(6304):1129-32. doi: 10.1126/science.aah6157. Epub 2016 Aug 4.


Vaccine protection against Zika virus from Brazil.

Larocca RA, Abbink P, Peron JP, Zanotto PM, Iampietro MJ, Badamchi-Zadeh A, Boyd M, Ng'ang'a D, Kirilova M, Nityanandam R, Mercado NB, Li Z, Moseley ET, Bricault CA, Borducchi EN, Giglio PB, Jetton D, Neubauer G, Nkolola JP, Maxfield LF, De La Barrera RA, Jarman RG, Eckels KH, Michael NL, Thomas SJ, Barouch DH.

Nature. 2016 Aug 25;536(7617):474-8. Epub 2016 Jun 28.


Fateful music from a talented orchestra with a wicked conductor: Connection between oncogenic BRAF, ER stress, and autophagy in human melanoma.

Giglio P, Fimia GM, Lovat PE, Piacentini M, Corazzari M.

Mol Cell Oncol. 2015 Jan 26;2(3):e995016. doi: 10.4161/23723556.2014.995016. eCollection 2015 Jul-Sep.


RIP1 and RIP3 complex regulates radiation-induced programmed necrosis in glioblastoma.

Das A, McDonald DG, Dixon-Mah YN, Jacqmin DJ, Samant VN, Vandergrift WA 3rd, Lindhorst SM, Cachia D, Varma AK, Vanek KN, Banik NL, Jenrette JM 3rd, Raizer JJ, Giglio P, Patel SJ.

Tumour Biol. 2016 Jun;37(6):7525-34. doi: 10.1007/s13277-015-4621-6. Epub 2015 Dec 18.


Synergistic Effects of Crizotinib and Temozolomide in Experimental FIG-ROS1 Fusion-Positive Glioblastoma.

Das A, Cheng RR, Hilbert ML, Dixon-Moh YN, Decandio M, Vandergrift WA 3rd, Banik NL, Lindhorst SM, Cachia D, Varma AK, Patel SJ, Giglio P.

Cancer Growth Metastasis. 2015 Dec 1;8:51-60. doi: 10.4137/CGM.S32801. eCollection 2015.


Clinical and economic impact of antimicrobial stewardship interventions with the FilmArray blood culture identification panel.

Pardo J, Klinker KP, Borgert SJ, Butler BM, Giglio PG, Rand KH.

Diagn Microbiol Infect Dis. 2016 Feb;84(2):159-64. doi: 10.1016/j.diagmicrobio.2015.10.023. Epub 2015 Nov 11.


Mucocutaneous manifestations of helminth infections: Trematodes and cestodes.

Lupi O, Downing C, Lee M, Bravo F, Giglio P, Woc-Colburn L, Tyring SK.

J Am Acad Dermatol. 2015 Dec;73(6):947-57; quiz 957-8. doi: 10.1016/j.jaad.2014.11.035. Review.


Mucocutaneous manifestations of helminth infections: Nematodes.

Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK.

J Am Acad Dermatol. 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. Review.


A phase II study of bevacizumab and erlotinib after radiation and temozolomide in MGMT unmethylated GBM patients.

Raizer JJ, Giglio P, Hu J, Groves M, Merrell R, Conrad C, Phuphanich S, Puduvalli VK, Loghin M, Paleologos N, Yuan Y, Liu D, Rademaker A, Yung WK, Vaillant B, Rudnick J, Chamberlain M, Vick N, Grimm S, Tremont-Lukats IW, De Groot J, Aldape K, Gilbert MR; Brain Tumor Trials Collaborative.

J Neurooncol. 2016 Jan;126(1):185-192. doi: 10.1007/s11060-015-1958-z.


Cartilage lesions and ankle osteoarthrosis: review of the literature and treatment algorithm.

Santos AL, Demange MK, Prado MP, Fernandes TD, Giglio PN, Hintermann B.

Rev Bras Ortop. 2014 Nov 11;49(6):565-72. doi: 10.1016/j.rboe.2014.11.003. eCollection 2014 Nov-Dec.


A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway.

Das A, Miller R, Lee P, Holden CA, Lindhorst SM, Jaboin J, Vandergrift WA 3rd, Banik NL, Giglio P, Varma AK, Raizer JJ, Patel SJ.

Tumour Biol. 2015 Sep;36(9):7027-34. doi: 10.1007/s13277-015-3388-0. Epub 2015 Apr 12.


Mechanisms and clinical significance of histone deacetylase inhibitors: epigenetic glioblastoma therapy.

Lee P, Murphy B, Miller R, Menon V, Banik NL, Giglio P, Lindhorst SM, Varma AK, Vandergrift WA 3rd, Patel SJ, Das A.

Anticancer Res. 2015 Feb;35(2):615-25. Review.


Downregulation of E2F1 during ER stress is required to induce apoptosis.

Pagliarini V, Giglio P, Bernardoni P, De Zio D, Fimia GM, Piacentini M, Corazzari M.

J Cell Sci. 2015 Mar 15;128(6):1166-79. doi: 10.1242/jcs.164103. Epub 2015 Jan 22.


Molecular Targets and Treatment of Meningioma.

Miller R Jr, DeCandio ML, Dixon-Mah Y, Giglio P, Vandergrift WA 3rd, Banik NL, Patel SJ, Varma AK, Das A.

J Neurol Neurosurg. 2014;1(1). pii: 1000101.


Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma.

Corazzari M, Rapino F, Ciccosanti F, Giglio P, Antonioli M, Conti B, Fimia GM, Lovat PE, Piacentini M.

Cell Death Differ. 2015 Jun;22(6):946-58. doi: 10.1038/cdd.2014.183. Epub 2014 Nov 7.


Current Studies of Immunotherapy on Glioblastoma.

Agrawal NS, Miller R Jr, Lal R, Mahanti H, Dixon-Mah YN, DeCandio ML, Vandergrift WA 3rd, Varma AK, Patel SJ, Banik NL, Lindhorst SM, Giglio P, Das A.

J Neurol Neurosurg. 2014 Apr 5;1(1). pii: 21000104.


Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma.

Penas-Prado M, Hess KR, Fisch MJ, Lagrone LW, Groves MD, Levin VA, De Groot JF, Puduvalli VK, Colman H, Volas-Redd G, Giglio P, Conrad CA, Salacz ME, Floyd JD, Loghin ME, Hsu SH, Gonzalez J, Chang EL, Woo SY, Mahajan A, Aldape KD, Yung WK, Gilbert MR; MD Anderson Community Clinical Oncology Program; Brain Tumor Trials Collaborative.

Neuro Oncol. 2015 Feb;17(2):266-73. doi: 10.1093/neuonc/nou155. Epub 2014 Sep 19.


Correlation between cerebral blood volume measurements by perfusion-weighted magnetic resonance imaging and two-year progression-free survival in gliomas.

Spampinato MV, Schiarelli C, Cianfoni A, Giglio P, Welsh CT, Bisdas S, Rumboldt Z.

Neuroradiol J. 2013 Aug;26(4):385-95. Epub 2013 Aug 27.


Obesity is a risk factor for significant carotid atherosclerosis in patients aged 39 to 55 years.

Silva ES, Giglio PN, Waisberg DR, Filho RG, Casella IB, Puech-Leão P.

Angiology. 2014 Aug;65(7):602-6. doi: 10.1177/0003319713494753. Epub 2013 Jul 11.


Multi-targeted DATS prevents tumor progression and promotes apoptosis in ectopic glioblastoma xenografts in SCID mice via HDAC inhibition.

Wallace GC 4th, Haar CP, Vandergrift WA 3rd, Giglio P, Dixon-Mah YN, Varma AK, Ray SK, Patel SJ, Banik NL, Das A.

J Neurooncol. 2013 Aug;114(1):43-50. doi: 10.1007/s11060-013-1165-8. Epub 2013 Jun 11.


Targeting oncogenic ALK and MET: a promising therapeutic strategy for glioblastoma.

Wallace GC 4th, Dixon-Mah YN, Vandergrift WA 3rd, Ray SK, Haar CP, Mittendorf AM, Patel SJ, Banik NL, Giglio P, Das A.

Metab Brain Dis. 2013 Sep;28(3):355-66. doi: 10.1007/s11011-013-9401-7. Epub 2013 Apr 2. Review.


Depression and Anxiety Symptoms Relate to Distinct Components of Pain Experience among Patients with Breast Cancer.

Galloway SK, Baker M, Giglio P, Chin S, Madan A, Malcolm R, Serber ER, Wedin S, Balliet W, Borckardt J.

Pain Res Treat. 2012;2012:851276. doi: 10.1155/2012/851276. Epub 2012 Nov 21.


Predicting trends in HIV-1 sexual transmission in sub-Saharan Africa through the Drug Resource Enhancement Against AIDS and Malnutrition model: antiretrovirals for 5 reduction of population infectivity, incidence and prevalence at the district level.

Palombi L, Bernava GM, Nucita A, Giglio P, Liotta G, Nielsen-Saines K, Orlando S, Mancinelli S, Buonomo E, Scarcella P, Altan AM, Guidotti G, Ceffa S, Haswell J, Zimba I, Magid NA, Marazzi MC.

Clin Infect Dis. 2012 Jul;55(2):268-75. doi: 10.1093/cid/cis380. Epub 2012 Apr 5.


Drug resistance in glioblastoma: a mini review.

Haar CP, Hebbar P, Wallace GC 4th, Das A, Vandergrift WA 3rd, Smith JA, Giglio P, Patel SJ, Ray SK, Banik NL.

Neurochem Res. 2012 Jun;37(6):1192-200. doi: 10.1007/s11064-011-0701-1. Epub 2012 Jan 10. Review.


Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma.

Giglio P, Dhamne M, Hess KR, Gilbert MR, Groves MD, Levin VA, Kang SL, Ictech SE, Liu V, Colman H, Conrad CA, Loghin M, de Groot J, Yung WK, Puduvalli VK.

Cancer. 2012 Jul 15;118(14):3599-606. doi: 10.1002/cncr.26663. Epub 2011 Nov 15.


Hippocampal plasticity in rats submitted to a gastric restrictive procedure.

Sonoda EY, Gomes da Silva S, Arida RM, Giglio PN, Margarido NF, Martinez CA, Pansani AP, Maciel Rde S, Cavalheiro EA, Scorza FA.

Nutr Neurosci. 2011 Sep;14(5):181-5. doi: 10.1179/1476830511Y.0000000009.


Cost-effectiveness of using HAART in prevention of mother-to-child transmission in the DREAM-Project Malawi.

Orlando S, Marazzi MC, Mancinelli S, Liotta G, Ceffa S, Giglio P, Alumando E, Ziegler I, Shawa M, Palombi L.

J Acquir Immune Defic Syndr. 2010 Dec 15;55(5):631-4. doi: 10.1097/QAI.0b013e3181f9f9f5.


Neurological deficits during treatment with tumor necrosis factor-alpha antagonists.

Nozaki K, Silver RM, Stickler DE, Abou-Fayssal NG, Giglio P, Kamen DL, Daniel R, Judson MA.

Am J Med Sci. 2011 Nov;342(5):352-5. doi: 10.1097/MAJ.0b013e31822b7bb8. Review.


Glioneuronal tumor with neuropil-like islands of the spinal cord with diffuse leptomeningeal neuraxis dissemination.

Ruppert B, Welsh CT, Hannah J, Giglio P, Rumboldt Z, Johnson I, Fortney J, Jenrette JM, Patel S, Scheithauer BW.

J Neurooncol. 2011 Sep;104(2):529-33. doi: 10.1007/s11060-010-0505-1. Epub 2010 Dec 25.


Metastatic hepatocellular carcinoma with associated spinal cord compression.

Vargas J, Gowans M, Vandergrift WA, Hope J, Giglio P.

Am J Med Sci. 2011 Feb;341(2):148-52. doi: 10.1097/MAJ.0b013e3181f7a49a. Review.


Newly diagnosed high-grade gliomas.

Giglio P, Villano JL.

Curr Treat Options Neurol. 2010 Jul;12(4):309-20. doi: 10.1007/s11940-010-0077-6.


Concomitant lymphoma and cryptococcosis in a patient with acquired immune deficiency syndrome.

Shukla BS, Giglio P, Couch JE, Hasija N, Krishna V, Frankel BM, Welsh CT.

Am J Med Sci. 2010 Oct;340(4):340-2. doi: 10.1097/MAJ.0b013e3181ef173f. No abstract available.


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