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Items: 38

1.

Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.

Pfuhl C, Grittner U, Gieß RM, Scheel M, Behrens JR, Rasche L, Pache FC, Wenzel R, Brandt AU, Bellmann-Strobl J, Paul F, Ruprecht K, Oechtering J.

Neurology. 2019 Oct 8;93(15):e1439-e1451. doi: 10.1212/WNL.0000000000008237. Epub 2019 Sep 9.

PMID:
31501228
2.

MRI Markers and Functional Performance in Patients With CIS and MS: A Cross-Sectional Study.

Rasche L, Scheel M, Otte K, Althoff P, van Vuuren AB, Gieß RM, Kuchling J, Bellmann-Strobl J, Ruprecht K, Paul F, Brandt AU, Schmitz-Hübsch T.

Front Neurol. 2018 Aug 29;9:718. doi: 10.3389/fneur.2018.00718. eCollection 2018.

3.

7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions.

Behrens JR, Wanner J, Kuchling J, Ostendorf L, Harms L, Ruprecht K, Niendorf T, Jarius S, Wildemann B, Gieß RM, Scheel M, Bellmann-Strobl J, Wuerfel J, Paul F, Sinnecker T.

Ann Clin Transl Neurol. 2018 Jun 29;5(8):900-912. doi: 10.1002/acn3.572. eCollection 2018 Aug.

4.

Association of Retinal Ganglion Cell Layer Thickness With Future Disease Activity in Patients With Clinically Isolated Syndrome.

Zimmermann HG, Knier B, Oberwahrenbrock T, Behrens J, Pfuhl C, Aly L, Kaminski M, Hoshi MM, Specovius S, Giess RM, Scheel M, Mühlau M, Bellmann-Strobl J, Ruprecht K, Hemmer B, Korn T, Paul F, Brandt AU.

JAMA Neurol. 2018 Sep 1;75(9):1071-1079. doi: 10.1001/jamaneurol.2018.1011.

5.

Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis.

Gieß RM, Pfuhl C, Behrens JR, Rasche L, Freitag E, Khalighy N, Otto C, Wuerfel J, Brandt AU, Hofmann J, Eberspächer B, Bellmann-Strobl J, Paul F, Ruprecht K.

PLoS One. 2017 Apr 7;12(4):e0175279. doi: 10.1371/journal.pone.0175279. eCollection 2017.

6.

Retinal imaging and axonal degeneration in later onset multiple sclerosis.

Huhn K, Lämmer R, Zimmermann H, Lämmer A, Waschbisch A, Utz K, Gieß RM, Paul F, Linker RA, Lee DH.

J Neurol Sci. 2016 Nov 15;370:1-6. doi: 10.1016/j.jns.2016.09.009. Epub 2016 Sep 8.

PMID:
27772735
7.

Fine specificity of the antibody response to Epstein-Barr nuclear antigen-2 and other Epstein-Barr virus proteins in patients with clinically isolated syndrome: A peptide microarray-based case-control study.

Schlemm L, Giess RM, Rasche L, Pfuhl C, Wakonig K, Behrens JR, Scheibenbogen C, Bellmann-Strobl J, Paul F, Reimer U, Ruprecht K.

J Neuroimmunol. 2016 Aug 15;297:56-62. doi: 10.1016/j.jneuroim.2016.05.012. Epub 2016 May 13.

PMID:
27397076
8.

Analysis of Lymphocytic DNA Damage in Early Multiple Sclerosis by Automated Gamma-H2AX and 53BP1 Foci Detection: A Case Control Study.

Rasche L, Heiserich L, Behrens JR, Lenz K, Pfuhl C, Wakonig K, Gieß RM, Freitag E, Eberle C, Wuerfel J, Dörr J, Bauer P, Bellmann-Strobl J, Paul F, Roggenbuck D, Ruprecht K.

PLoS One. 2016 Jan 28;11(1):e0147968. doi: 10.1371/journal.pone.0147968. eCollection 2016.

9.

Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis.

Keller A, Leidinger P, Meese E, Haas J, Backes C, Rasche L, Behrens JR, Pfuhl C, Wakonig K, Gieß RM, Jarius S, Meder B, Bellmann-Strobl J, Paul F, Pache FC, Ruprecht K.

J Neuroinflammation. 2015 Oct 31;12:196. doi: 10.1186/s12974-015-0418-1.

10.

Low 25-hydroxyvitamin D, but not the bioavailable fraction of 25-hydroxyvitamin D, is a risk factor for multiple sclerosis.

Behrens JR, Rasche L, Gieß RM, Pfuhl C, Wakonig K, Freitag E, Deuschle K, Bellmann-Strobl J, Paul F, Ruprecht K, Dörr J.

Eur J Neurol. 2016 Jan;23(1):62-7. doi: 10.1111/ene.12788. Epub 2015 Jul 28.

PMID:
26220765
11.

Association of serum Epstein-Barr nuclear antigen-1 antibodies and intrathecal immunoglobulin synthesis in early multiple sclerosis.

Pfuhl C, Oechtering J, Rasche L, Gieß RM, Behrens JR, Wakonig K, Freitag E, Pache FC, Otto C, Hofmann J, Eberspächer B, Bellmann-Strobl J, Paul F, Ruprecht K.

J Neuroimmunol. 2015 Aug 15;285:156-60. doi: 10.1016/j.jneuroim.2015.06.012. Epub 2015 Jun 25.

PMID:
26198934
12.

Neuronal Na+/K+ ATPase is an autoantibody target in paraneoplastic neurologic syndrome.

Scharf M, Miske R, Heidenreich F, Giess R, Landwehr P, Blöcker IM, Begemann N, Denno Y, Tiede S, Dähnrich C, Schlumberger W, Unger M, Teegen B, Stöcker W, Probst C, Komorowski L.

Neurology. 2015 Apr 21;84(16):1673-9. doi: 10.1212/WNL.0000000000001493. Epub 2015 Mar 25.

PMID:
25809299
13.

Multiple sclerosis: the elevated antibody response to Epstein-Barr virus primarily targets, but is not confined to, the glycine-alanine repeat of Epstein-Barr nuclear antigen-1.

Ruprecht K, Wunderlich B, Gieß R, Meyer P, Loebel M, Lenz K, Hofmann J, Rosche B, Wengert O, Paul F, Reimer U, Scheibenbogen C.

J Neuroimmunol. 2014 Jul 15;272(1-2):56-61. doi: 10.1016/j.jneuroim.2014.04.005. Epub 2014 Apr 16.

PMID:
24798244
14.

Paraneoplastic autoimmune encephalitis associated with CV2/CRMP-5 IgG antineuronal antibodies in a patient with thymoma.

Werry C, Götz F, Wurster U, Stangel M, Giess R, Heidenreich F, Windhagen A.

J Neurol. 2009 Jan;256(1):129-31. doi: 10.1007/s00415-009-0826-1. Epub 2009 Feb 16. No abstract available.

PMID:
19267170
15.

Botulinum neurotoxin type A injections reduce spasticity in mild to moderate hereditary spastic paraplegia--report of 19 cases.

Hecht MJ, Stolze H, Auf dem Brinke M, Giess R, Treig T, Winterholler M, Wissel J; German Spasticity Education Group.

Mov Disord. 2008 Jan 30;23(2):228-33.

PMID:
17999430
16.

Autonomic dysfunction in ALS: a preliminary study on the effects of intrathecal BDNF.

Beck M, Flachenecker P, Magnus T, Giess R, Reiners K, Toyka KV, Naumann M.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2005 Jun;6(2):100-3.

PMID:
16036433
17.

Leukaemia inhibitory factor (LIF) gene mutations in women with unexplained infertility and recurrent failure of implantation after IVF and embryo transfer.

Steck T, Giess R, Suetterlin MW, Bolland M, Wiest S, Poehls UG, Dietl J.

Eur J Obstet Gynecol Reprod Biol. 2004 Jan 15;112(1):69-73.

PMID:
14687743
18.

MRI after thoracic epidural blood patch.

Giess R, Landwehr P, Heidenreich F.

Neurology. 2003 Nov 25;61(10):1449. No abstract available.

PMID:
14638978
19.

Impaired salivary gland function reveals autonomic dysfunction in amyotrophic lateral sclerosis.

Giess R, Werner E, Beck M, Reiners C, Toyka KV, Naumann M.

J Neurol. 2002 Sep;249(9):1246-9.

PMID:
12242548
20.

Progressive sudomotor dysfunction in amyotrophic lateral sclerosis.

Beck M, Giess R, Magnus T, Puls I, Reiners K, Toyka KV, Naumann M.

J Neurol Neurosurg Psychiatry. 2002 Jul;73(1):68-70.

21.

CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation.

Linker RA, Mäurer M, Gaupp S, Martini R, Holtmann B, Giess R, Rieckmann P, Lassmann H, Toyka KV, Sendtner M, Gold R.

Nat Med. 2002 Jun;8(6):620-4.

PMID:
12042814
22.

Disease progression in amyotrophic lateral sclerosis: predictors of survival.

Magnus T, Beck M, Giess R, Puls I, Naumann M, Toyka KV.

Muscle Nerve. 2002 May;25(5):709-14.

PMID:
11994965
23.

Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene.

Giess R, Holtmann B, Braga M, Grimm T, Müller-Myhsok B, Toyka KV, Sendtner M.

Am J Hum Genet. 2002 May;70(5):1277-86. Epub 2002 Apr 9.

24.

Association of a null mutation in the CNTF gene with early onset of multiple sclerosis.

Giess R, Mäurer M, Linker R, Gold R, Warmuth-Metz M, Toyka KV, Sendtner M, Rieckmann P.

Arch Neurol. 2002 Mar;59(3):407-9.

PMID:
11890844
25.

[Ciguatera: clinical relevance of a marine neurotoxin].

Ruprecht K, Rieckmann P, Giess R.

Dtsch Med Wochenschr. 2001 Jul 13;126(28-29):812-4. German.

PMID:
11499263
26.

A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis.

Ochs G, Penn RD, York M, Giess R, Beck M, Tonn J, Haigh J, Malta E, Traub M, Sendtner M, Toyka KV.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2000 Jun;1(3):201-6.

PMID:
11464953
27.

Injections of botulinum toxin A into the salivary glands improve sialorrhoea in amyotrophic lateral sclerosis.

Giess R, Naumann M, Werner E, Riemann R, Beck M, Puls I, Reiners C, Toyka KV.

J Neurol Neurosurg Psychiatry. 2000 Jul;69(1):121-3.

28.

Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis.

Giess R, Beck M, Goetz R, Nitsch RM, Toyka KV, Sendtner M.

Neurology. 2000 Feb 22;54(4):1003-5.

PMID:
10691006
29.

Genetic variation at position -1082 of the interleukin 10 (IL10) promotor and the outcome of multiple sclerosis.

Mäurer M, Kruse N, Giess R, Toyka KV, Rieckmann P.

J Neuroimmunol. 2000 Apr 3;104(1):98-100.

PMID:
10683520
30.

[Clenbuterol in amyotrophic lateral sclerosis. No indication for a positive effect].

Puls I, Beck M, Giess R, Magnus T, Ochs G, Toyka KV.

Nervenarzt. 1999 Dec;70(12):1112-5. Review. German.

PMID:
10637819
31.

[Unilateral mydriasis after cutting back angel trumpet].

Giess R, Müllges W.

Dtsch Med Wochenschr. 1999 Dec 3;124(48):1456. German. No abstract available.

PMID:
10615327
32.

Gene polymorphism at position -308 of the tumor necrosis factor alpha promotor is not associated with disease progression in multiple sclerosis patients.

Mäurer M, Kruse N, Giess R, Kyriallis K, Toyka KV, Rieckmann P.

J Neurol. 1999 Oct;246(10):949-54.

PMID:
10552245
33.

Epi-arachnoidal drug deposit: a rare complication of intrathecal drug therapy.

Ochs G, Giess R, Bendszus M, Krone A.

J Pain Symptom Manage. 1999 Sep;18(3):229-32.

PMID:
10517046
34.
35.

Leukaemia inhibitory factor gene mutations in infertile women.

Giess R, Tanasescu I, Steck T, Sendtner M.

Mol Hum Reprod. 1999 Jun;5(6):581-6.

PMID:
10341007
36.

[Juvenile cerebral ischaemia caused by designer drugs].

Giess R, Rieckmann P, Müllges W.

Dtsch Med Wochenschr. 1998 Oct 30;123(44):1308-12. German.

PMID:
9824966
37.

Potential implications of a ciliary neurotrophic factor gene mutation in a German population of patients with motor neuron disease.

Giess R, Goetz R, Schrank B, Ochs G, Sendtner M, Toyka K.

Muscle Nerve. 1998 Feb;21(2):236-8.

PMID:
9466600
38.

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