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Items: 16


TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures.

Tu AA, Gierahn TM, Monian B, Morgan DM, Mehta NK, Ruiter B, Shreffler WG, Shalek AK, Love JC.

Nat Immunol. 2019 Dec;20(12):1692-1699. doi: 10.1038/s41590-019-0544-5. Epub 2019 Nov 19.


Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen specific memory B cell repertoires.

Jia B, McNeil LK, Dupont CD, Tsioris K, Barry RM, Scully IL, Ogunniyi AO, Gonzalez C, Pride MW, Gierahn TM, Liberator PA, Jansen KU, Love JC.

PLoS One. 2017 Sep 14;12(9):e0183738. doi: 10.1371/journal.pone.0183738. eCollection 2017.


Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput.

Gierahn TM, Wadsworth MH 2nd, Hughes TK, Bryson BD, Butler A, Satija R, Fortune S, Love JC, Shalek AK.

Nat Methods. 2017 Apr;14(4):395-398. doi: 10.1038/nmeth.4179. Epub 2017 Feb 13.


Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity.

Donius LR, Cheng Y, Choi J, Sun ZY, Hanson M, Zhang M, Gierahn TM, Marquez S, Uduman M, Kleinstein SH, Irvine D, Love JC, Reinherz EL, Kim M.

J Virol. 2016 Sep 12;90(19):8875-90. doi: 10.1128/JVI.01089-16. Print 2016 Oct 1.


Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes.

Liao MC, Muratore CR, Gierahn TM, Sullivan SE, Srikanth P, De Jager PL, Love JC, Young-Pearse TL.

J Neurosci. 2016 Feb 3;36(5):1730-46. doi: 10.1523/JNEUROSCI.2735-15.2016.


Resolution of Chlamydia trachomatis Infection Is Associated with a Distinct T Cell Response Profile.

Picard MD, Bodmer JL, Gierahn TM, Lee A, Price J, Cohane K, Clemens V, DeVault VL, Gurok G, Kohberger R, Higgins DE, Siber GR, Flechtner JB, Geisler WM.

Clin Vaccine Immunol. 2015 Nov;22(11):1206-18. doi: 10.1128/CVI.00247-15. Epub 2015 Oct 7.


Identification of novel virus-specific antigens by CD4⁺ and CD8⁺ T cells from asymptomatic HSV-2 seropositive and seronegative donors.

Long D, Skoberne M, Gierahn TM, Larson S, Price JA, Clemens V, Baccari AE, Cohane KP, Garvie D, Siber GR, Flechtner JB.

Virology. 2014 Sep;464-465:296-311. doi: 10.1016/j.virol.2014.07.018. Epub 2014 Aug 9.


Functional analysis of single cells identifies a rare subset of circulating tumor cells with malignant traits.

Yao X, Choudhury AD, Yamanaka YJ, Adalsteinsson VA, Gierahn TM, Williamson CA, Lamb CR, Taplin ME, Nakabayashi M, Chabot MS, Li T, Lee GS, Boehm JS, Kantoff PW, Hahn WC, Wittrup KD, Love JC.

Integr Biol (Camb). 2014 Apr;6(4):388-98. doi: 10.1039/c3ib40264a. Epub 2014 Feb 13.


Single-cell technologies for monitoring immune systems.

Chattopadhyay PK, Gierahn TM, Roederer M, Love JC.

Nat Immunol. 2014 Feb;15(2):128-35. doi: 10.1038/ni.2796. Review.


Crossword: a fully automated algorithm for the segmentation and quality control of protein microarray images.

Gierahn TM, Loginov D, Love JC.

J Proteome Res. 2014 Feb 7;13(2):362-71. doi: 10.1021/pr401167h. Epub 2014 Jan 24.


Cellular barcodes for efficiently profiling single-cell secretory responses by microengraving.

Yamanaka YJ, Szeto GL, Gierahn TM, Forcier TL, Benedict KF, Brefo MS, Lauffenburger DA, Irvine DJ, Love JC.

Anal Chem. 2012 Dec 18;84(24):10531-6. doi: 10.1021/ac302264q. Epub 2012 Dec 3.


The dynamic lives of T cells: new approaches and themes.

Yamanaka YJ, Gierahn TM, Love JC.

Trends Immunol. 2013 Feb;34(2):59-66. doi: 10.1016/ Epub 2012 Nov 28. Review.


High-throughput proteomic screening identifies Chlamydia trachomatis antigens that are capable of eliciting T cell and antibody responses that provide protection against vaginal challenge.

Picard MD, Cohane KP, Gierahn TM, Higgins DE, Flechtner JB.

Vaccine. 2012 Jun 19;30(29):4387-93. doi: 10.1016/j.vaccine.2012.01.017.


Immuno-hybridization chain reaction for enhancing detection of individual cytokine-secreting human peripheral mononuclear cells.

Choi J, Love KR, Gong Y, Gierahn TM, Love JC.

Anal Chem. 2011 Sep 1;83(17):6890-5. doi: 10.1021/ac2013916. Epub 2011 Aug 15.


T(H)17-based vaccine design for prevention of Streptococcus pneumoniae colonization.

Moffitt KL, Gierahn TM, Lu YJ, Gouveia P, Alderson M, Flechtner JB, Higgins DE, Malley R.

Cell Host Microbe. 2011 Feb 17;9(2):158-65. doi: 10.1016/j.chom.2011.01.007.


Monitoring the T cell response to genital tract infection.

Roan NR, Gierahn TM, Higgins DE, Starnbach MN.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12069-74. Epub 2006 Jul 31.

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