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Items: 1 to 50 of 395

1.

Donald Seldin: A Transformative Leader in Medicine and Nephrology.

Alpern R, Giebisch G.

J Am Soc Nephrol. 2018 Aug;29(8):2029-2030. doi: 10.1681/ASN.2018060603. Epub 2018 Jul 9. No abstract available.

2.

Potassium Channelopathies and Gastrointestinal Ulceration.

Han J, Lee SH, Giebisch G, Wang T.

Gut Liver. 2016 Nov 15;10(6):881-889. doi: 10.5009/gnl15414. Review.

3.

Romk1 Knockout Mice Do Not Produce Bartter Phenotype but Exhibit Impaired K Excretion.

Dong K, Yan Q, Lu M, Wan L, Hu H, Guo J, Boulpaep E, Wang W, Giebisch G, Hebert SC, Wang T.

J Biol Chem. 2016 Mar 4;291(10):5259-69. doi: 10.1074/jbc.M115.707877. Epub 2016 Jan 4.

4.

Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).

Lin DH, Yue P, Yarborough O 3rd, Scholl UI, Giebisch G, Lifton RP, Rinehart J, Wang WH.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4495-500. doi: 10.1073/pnas.1503437112. Epub 2015 Mar 24.

5.

KCNJ10 determines the expression of the apical Na-Cl cotransporter (NCC) in the early distal convoluted tubule (DCT1).

Zhang C, Wang L, Zhang J, Su XT, Lin DH, Scholl UI, Giebisch G, Lifton RP, Wang WH.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11864-9. doi: 10.1073/pnas.1411705111. Epub 2014 Jul 28.

6.

Renal potassium homeostasis: a short historical perspective.

Giebisch GH, Wingo CS.

Semin Nephrol. 2013 May;33(3):209-14. doi: 10.1016/j.semnephrol.2013.05.001.

PMID:
23953798
7.

Angiotensin II stimulates H⁺-ATPase activity in intercalated cells from isolated mouse connecting tubules and cortical collecting ducts.

Wagner CA, Mohebbi N, Uhlig U, Giebisch GH, Breton S, Brown D, Geibel JP.

Cell Physiol Biochem. 2011;28(3):513-20. doi: 10.1159/000335112. Epub 2011 Nov 18.

8.

Effects of pH on potassium: new explanations for old observations.

Aronson PS, Giebisch G.

J Am Soc Nephrol. 2011 Nov;22(11):1981-9. doi: 10.1681/ASN.2011040414. Epub 2011 Oct 6.

9.

Potassium transport--an update.

Giebisch GH, Wang WH.

J Nephrol. 2010 Nov-Dec;23 Suppl 16:S97-104. Review.

PMID:
21170894
10.

A long affair with renal tubules.

Giebisch GH.

Annu Rev Physiol. 2011;73:1-28. doi: 10.1146/annurev-physiol-012110-142241.

PMID:
20690822
11.

Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct.

Lu M, Dong K, Egan ME, Giebisch GH, Boulpaep EL, Hebert SC.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6082-7. doi: 10.1073/pnas.0902661107. Epub 2010 Mar 15.

12.

POSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels.

Lin DH, Yue P, Pan CY, Sun P, Zhang X, Han Z, Roos M, Caplan M, Giebisch G, Wang WH.

J Biol Chem. 2009 Oct 23;284(43):29614-24. doi: 10.1074/jbc.M109.041582. Epub 2009 Aug 26.

13.

Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels.

Yue P, Lin DH, Pan CY, Leng Q, Giebisch G, Lifton RP, Wang WH.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):15061-6. doi: 10.1073/pnas.0907855106. Epub 2009 Aug 18.

14.

Torasemide significantly reduces thiazide-induced potassium and magnesium loss despite supra-additive natriuresis.

Knauf H, Mutschler E, Velazquez H, Giebisch G.

Eur J Clin Pharmacol. 2009 May;65(5):465-72. doi: 10.1007/s00228-009-0626-7. Epub 2009 Feb 20.

PMID:
19229529
15.

Regulation of potassium (K) handling in the renal collecting duct.

Wang WH, Giebisch G.

Pflugers Arch. 2009 May;458(1):157-68. doi: 10.1007/s00424-008-0593-3. Epub 2008 Oct 7. Review.

16.

Basolateral Na+/H+ exchange maintains potassium secretion during diminished sodium transport in the rabbit cortical collecting duct.

Muto S, Tsuruoka S, Miyata Y, Fujimura A, Kusano E, Wang W, Seldin D, Giebisch G.

Kidney Int. 2009 Jan;75(1):25-30. doi: 10.1038/ki.2008.447. Epub 2008 Sep 3.

17.

Female ROMK null mice manifest more severe Bartter II phenotype on renal function and higher PGE2 production.

Yan Q, Yang X, Cantone A, Giebisch G, Hebert S, Wang T.

Am J Physiol Regul Integr Comp Physiol. 2008 Sep;295(3):R997-R1004. doi: 10.1152/ajpregu.00051.2007. Epub 2008 Jun 25.

18.

Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity.

Cantone A, Yang X, Yan Q, Giebisch G, Hebert SC, Wang T.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1366-72. doi: 10.1152/ajprenal.00608.2007. Epub 2008 Apr 2.

19.

Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins.

Wagner CA, Loffing-Cueni D, Yan Q, Schulz N, Fakitsas P, Carrel M, Wang T, Verrey F, Geibel JP, Giebisch G, Hebert SC, Loffing J.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1373-80. doi: 10.1152/ajprenal.00613.2007. Epub 2008 Mar 5.

20.

A novel protein kinase signaling pathway essential for blood pressure regulation in humans.

Kahle KT, Rinehart J, Giebisch G, Gamba G, Hebert SC, Lifton RP.

Trends Endocrinol Metab. 2008 Apr;19(3):91-5. doi: 10.1016/j.tem.2008.01.001. Epub 2008 Feb 14. Review.

PMID:
18280177
21.

Renal and extrarenal regulation of potassium.

Giebisch G, Krapf R, Wagner C.

Kidney Int. 2007 Aug;72(4):397-410. Epub 2007 Jun 13.

22.

Inhibitor of growth 4 (ING4) is up-regulated by a low K intake and suppresses renal outer medullary K channels (ROMK) by MAPK stimulation.

Zhang X, Lin DH, Jin Y, Wang KS, Zhang Y, Babilonia E, Wang Z, Wang Z, Giebisch G, Han ZG, Wang WH.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9517-22. Epub 2007 May 17.

23.

Inhibition of MAPK stimulates the Ca2+ -dependent big-conductance K channels in cortical collecting duct.

Li D, Wang Z, Sun P, Jin Y, Lin DH, Hebert SC, Giebisch G, Wang WH.

Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19569-74. Epub 2006 Dec 6.

24.

Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of Type II Bartter's syndrome and in adaptation to a high-K diet.

Bailey MA, Cantone A, Yan Q, MacGregor GG, Leng Q, Amorim JB, Wang T, Hebert SC, Giebisch G, Malnic G.

Kidney Int. 2006 Jul;70(1):51-9. Epub 2006 May 17.

25.

CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney.

Lu M, Leng Q, Egan ME, Caplan MJ, Boulpaep EL, Giebisch GH, Hebert SC.

J Clin Invest. 2006 Mar;116(3):797-807. Epub 2006 Feb 9.

26.

Subunit-subunit interactions are critical for proton sensitivity of ROMK: evidence in support of an intermolecular gating mechanism.

Leng Q, MacGregor GG, Dong K, Giebisch G, Hebert SC.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1982-7. Epub 2006 Jan 30.

27.

The B1-subunit of the H(+) ATPase is required for maximal urinary acidification.

Finberg KE, Wagner CA, Bailey MA, Paunescu TG, Breton S, Brown D, Giebisch G, Geibel JP, Lifton RP.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13616-21. Epub 2005 Sep 8.

28.

Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK).

O'Connell AD, Leng Q, Dong K, MacGregor GG, Giebisch G, Hebert SC.

Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9954-9. Epub 2005 Jun 29.

29.

ROMK1 channel activity is regulated by monoubiquitination.

Lin DH, Sterling H, Wang Z, Babilonia E, Yang B, Dong K, Hebert SC, Giebisch G, Wang WH.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4306-11. Epub 2005 Mar 14.

30.

Molecular diversity and regulation of renal potassium channels.

Hebert SC, Desir G, Giebisch G, Wang W.

Physiol Rev. 2005 Jan;85(1):319-71. Review.

31.

NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice.

Bailey MA, Giebisch G, Abbiati T, Aronson PS, Gawenis LR, Shull GE, Wang T.

J Physiol. 2004 Dec 15;561(Pt 3):765-75. Epub 2004 Oct 7.

32.
33.

Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension.

Kahle KT, Macgregor GG, Wilson FH, Van Hoek AN, Brown D, Ardito T, Kashgarian M, Giebisch G, Hebert SC, Boulpaep EL, Lifton RP.

Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14877-82. Epub 2004 Oct 1.

34.

Heini Murer: congratulations on his 60th birthday.

Giebisch G.

Pflugers Arch. 2004 Sep;448(6):557-60. Epub 2004 Aug 13. No abstract available.

PMID:
15316782
35.

Challenges to potassium metabolism: internal distribution and external balance.

Giebisch G.

Wien Klin Wochenschr. 2004 Jun 30;116(11-12):353-66. Review.

PMID:
15291287
36.

Homer W. Smith's contribution to renal physiology.

Giebisch G.

J Nephrol. 2004 Jan-Feb;17(1):159-65.

PMID:
15151273
37.

Protein tyrosine kinase is expressed and regulates ROMK1 location in the cortical collecting duct.

Lin DH, Sterling H, Yang B, Hebert SC, Giebisch G, Wang WH.

Am J Physiol Renal Physiol. 2004 May;286(5):F881-92.

38.

Roderick MacKinnon, MD, honored by 2003 Nobel Prize in Chemistry for work on elucidating the structure of ion channels.

Hebert SC, Giebisch G.

J Am Soc Nephrol. 2004 Apr;15(4):1096-7. No abstract available.

39.

Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosterone.

Winter C, Schulz N, Giebisch G, Geibel JP, Wagner CA.

Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2636-41.

40.

Localization and regulation of the ATP6V0A4 (a4) vacuolar H+-ATPase subunit defective in an inherited form of distal renal tubular acidosis.

Stehberger PA, Schulz N, Finberg KE, Karet FE, Giebisch G, Lifton RP, Geibel JP, Wagner CA.

J Am Soc Nephrol. 2003 Dec;14(12):3027-38.

41.

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion.

Kahle KT, Wilson FH, Leng Q, Lalioti MD, O'Connell AD, Dong K, Rapson AK, MacGregor GG, Giebisch G, Hebert SC, Lifton RP.

Nat Genet. 2003 Dec;35(4):372-6. Epub 2003 Nov 9.

PMID:
14608358
42.

ROMK is required for expression of the 70-pS K channel in the thick ascending limb.

Lu M, Wang T, Yan Q, Wang W, Giebisch G, Hebert SC.

Am J Physiol Renal Physiol. 2004 Mar;286(3):F490-5. Epub 2003 Nov 4.

43.

Activity of the basolateral K+ channels is coupled to the Na+-K+-ATPase in the cortical collecting duct.

Muto S, Asano Y, Wang W, Seldin D, Giebisch G.

Am J Physiol Renal Physiol. 2003 Nov;285(5):F945-54.

44.

Inhibition of heme oxygenase decreases sodium and fluid absorption in the loop of Henle.

Wang T, Sterling H, Shao WA, Yan Q, Bailey MA, Giebisch G, Wang WH.

Am J Physiol Renal Physiol. 2003 Sep;285(3):F484-90.

45.

Presentation of the 2001 A.N. Richards Award to Eberhard Frömter.

Giebisch G.

Kidney Int. 2003 Jun;63(6):2331-3. No abstract available.

46.

A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse.

Wagner CA, Lükewille U, Valles P, Breton S, Brown D, Giebisch GH, Geibel JP.

Pflugers Arch. 2003 Aug;446(5):623-32. Epub 2003 May 13.

PMID:
12748863
47.

Intracellular Na concentration and Rb uptake in proximal convoluted tubule cells and abundance of Na/K-ATPase alpha1-subunit in NHE3-/- mice.

Beck FX, Neuhofer W, Dörge A, Giebisch G, Wang T.

Pflugers Arch. 2003 Apr;446(1):100-5. Epub 2003 Feb 8.

PMID:
12690468
48.

New aspects of renal potassium transport.

Giebisch G, Hebert SC, Wang WH.

Pflugers Arch. 2003 Jun;446(3):289-97. Epub 2003 Apr 9. Review.

PMID:
12684792
49.

Role of luminal anion and pH in distal tubule potassium secretion.

Amorim JB, Bailey MA, Musa-Aziz R, Giebisch G, Malnic G.

Am J Physiol Renal Physiol. 2003 Feb;284(2):F381-8. Epub 2002 Oct 22.

50.

Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status.

Wagner CA, Finberg KE, Stehberger PA, Lifton RP, Giebisch GH, Aronson PS, Geibel JP.

Kidney Int. 2002 Dec;62(6):2109-17.

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